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Family Medicine

NICE Guideline: Hypertension in Pregnancy

26 Jun, 2019 | 07:54h | UTC

Hypertension in pregnancy: diagnosis and management – National Institute for Health and Care Excellence (free)

Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)

Related Reviews: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free) AND Hypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)

 


Did This Patient Have Cardiac Syncope? The Rational Clinical Examination Systematic Review

26 Jun, 2019 | 01:48h | UTC

Did This Patient Have Cardiac Syncope? The Rational Clinical Examination Systematic Review – JAMA (free for a limited period)

Related Guidelines: 2018 ESC Guidelines for the diagnosis and management of syncope – European Heart Journal (free) AND 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (free)

 


Study: Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality

26 Jun, 2019 | 02:24h | UTC

Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality – JAMA (free for a limited period)

Editorial: Accuracy of Airflow Obstruction Thresholds for Predicting COPD-Related Hospitalization and Mortality: Can Simple Diagnostic Thresholds Be Used for a Complex Disease? (free)

Commentary: Study funded by NIH supports optimal threshold for diagnosing COPD – NIH News Releases (free)

“These results support the use of FEV1:FVC less than 0.70 to identify individuals at risk of clinically significant COPD.”

 


Choosing Wisely – Case Studies from the Top 10 Recommendations Across Campaigns

26 Jun, 2019 | 01:24h | UTC

Choosing Wisely: Case Studies from the Top 10 Recommendations Across Campaigns – The Commonwealth Fund (free case studies)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

Related Commentary on Twitter


Alex Nowbar’s journal reviews – 25 June 2019

26 Jun, 2019 | 00:42h | UTC

Alex Nowbar’s journal reviews, 25 June 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


AAP Policy Statement: Alcohol Use by Youth

25 Jun, 2019 | 07:09h | UTC

Alcohol Use by Youth – Pediatrics (free)

Technical Report: Alcohol Use by Youth – Pediatrics (free)

News Release: American Academy of Pediatrics Emphasizes Dangers of Alcohol to Children, Teens and Young Adults – American Academy of Pediatrics (free)

 


Study: Anticholinergic Drug Exposure and the Risk of Dementia

25 Jun, 2019 | 07:03h | UTC

Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study – JAMA Internal Medicine (free)

Commentaries: Preventing Alzheimer Disease by Deprescribing Anticholinergic Medications – JAMA Internal Medicine (free for a limited period) AND Commonly prescribed anticholinergic drugs linked to dementia risk – UPI (free) AND Expert reaction to anticholinergic drug exposure and risk of dementia – Science Media Centre (free) Commonly prescribed drugs are tied to nearly 50% higher dementia risk in older adults, study says – CNN (free)

 


[Abstract Only] Meta-Analysis: Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess

25 Jun, 2019 | 06:33h | UTC

Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Incidentally discovered adrenal tumors rarely grow or affect hormonal function, review finds – ACP Internist (free) AND Healthcare guidelines should be updated for patients with certain adrenal tumors – University of Birmingham (free)

Related Guideline: Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors – European Journal of Endocrinology (free)

 


[Abstract Only] Randomized Trial: Effect of a Home-Based Exercise Program on Subsequent Falls Among High-Risk Older Adults

24 Jun, 2019 | 00:56h | UTC

Effect of a Home-Based Exercise Program on Subsequent Falls Among Community-Dwelling High-Risk Older Adults After a Fall: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Home exercise program reduces rate of falling in at-risk seniors – University of British Columbia (free) AND Home Based Physical Therapy Can Help Prevent Falls in the Elderly – MedicalResearch.com (free)

 


Study: Prevalence of Chronic Pain in Cancer Survivors

21 Jun, 2019 | 08:28h | UTC

Prevalence of Chronic Pain and High-Impact Chronic Pain in Cancer Survivors in the United States – JAMA Oncology (free for a limited period)

Commentaries: Nearly 5.4 million cancer survivors suffer chronic pain – American Cancer Society (free) AND One-third of cancer survivors experiences chronic pain, study says – UPI (free)

 


Alex Nowbar’s journal reviews—20 May 2019

21 Jun, 2019 | 08:01h | UTC

Alex Nowbar’s journal reviews, 20 May 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


CDC Study: Rotavirus Vaccination Associated With a Significant Reduction in Detected Cases

21 Jun, 2019 | 08:22h | UTC

Trends in the Laboratory Detection of Rotavirus Before and After Implementation of Routine Rotavirus Vaccination — United States, 2000–2018 – Centers for Disease Control and Prevention (free)

Commentary: Rotavirus Vaccination Tied to Large Drop in Infections – NEJM Journal Watch (free)

 


Opinion – “Debating Whether Checkups Are Time Wasted or Time Misused”

20 Jun, 2019 | 06:38h | UTC

Debating Whether Checkups Are Time Wasted or Time Misused – JAMA (free for a limited period)

Related Cochrane Review: General Health Checks for Reducing Illness and Mortality (free)

 


Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention

20 Jun, 2019 | 06:17h | UTC

Vitamin D Supplementation and Cardiovascular Disease Risks in More Than 83 000 Individuals in 21 Randomized Clinical Trials: A Meta-analysis – JAMA Cardiology (free for a limited period)

Commentaries: The Demise of Vitamin D for Cardiovascular Prevention – JAMA Cardiology (free for a limited period) AND Does Vitamin D Supplementation Provide Cardiovascular Protection? – MPR (free)

 

Related Commentary on Twitter

 

 


[Abstract Only] Randomized Trial: Septoplasty May Improve Quality of Life for Patients with Nasal Obstruction and a Deviated Septum

20 Jun, 2019 | 06:03h | UTC

Septoplasty with or without concurrent turbinate surgery versus non-surgical management for nasal obstruction in adults with a deviated septum: a pragmatic, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Surgery for Deviated Septum Linked to Better Quality of Life – NEJM Journal Watch (free)

 


USPSTF Draft Statement: Screening for Abdominal Aortic Aneurism

19 Jun, 2019 | 08:26h | UTC

Screening for Abdominal Aortic Aneurism – U.S. Preventive Services Task Force (free)

Commentary: USPSTF Reaffirms Recommendations on AAA Screening in Draft Statement – NEJM Journal Watch (free)

 


State of The Art Review: Advances in Rehabilitation for Chronic Diseases

18 Jun, 2019 | 06:59h | UTC

Advances in rehabilitation for chronic diseases: improving health outcomes and function – The BMJ (free)

 


Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors

18 Jun, 2019 | 06:42h | UTC

Association of Conventional Cardiovascular Risk Factors With Cardiovascular Disease After Hypertensive Disorders of Pregnancy: Analysis of the Nord-Trøndelag Health Study – JAMA Cardiology (free)

Commentary: Hypertension During Pregnancy Increases Later CVD Risk by More Than 50% – TCTMD (free)

Related: All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease (free) AND Hypertensive Disorders in Pregnancy and the Risk of Subsequent Cardiovascular Disease (free) AND Gestational Hypertension and Future Risk of Cardiovascular Disease (free) Research: Conjoint Associations of Gestational Diabetes and Hypertension With Diabetes, Hypertension, and Cardiovascular Disease in Parents (free) AND Cohort Study: Hypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease (link to abstract and commentaries)

 


Meta-Analysis: Safety and Efficacy of Aspirin for Primary Prevention of Cancer

17 Jun, 2019 | 01:44h | UTC

Safety and efficacy of aspirin for primary prevention of cancer: a meta-analysis of randomized controlled trials – Journal of Cancer Research and Clinical Oncology (free)

“Our study did not find any significant reductions in cancer-related mortality or cancer incidence when compared aspirin use with placebo or no aspirin.”

 


[Abstract Only] Randomized Trial: SGLT2 Inhibitor Reduces Adverse Renal Events in Patients with Type 2 Diabetes and Nephropathy

14 Jun, 2019 | 06:49h | UTC

Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation – CREDENCE – American College of Cardiology (free)

 


Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology

14 Jun, 2019 | 06:53h | UTC

Updated Geriatric Cardiology Guidelines of the Brazilian Society of Cardiology – 2019 – Arquivos Brasileiros de Cardiologia (free PDF)

 


Higher Doses of Antidepressants “Not Optimal”, According to New Review

14 Jun, 2019 | 02:32h | UTC

Higher doses of antidepressants “not optimal”, according to new review – The Mental Elf (free)

Original Article: Meta-analysis: Optimal Dose of Antidepressants in Major Depression (free study and commentaries)

 


[Abstract Only] Risks of 23 Specific Malformations Associated with Prenatal Exposure to 10 Antiepileptic Drugs

14 Jun, 2019 | 02:33h | UTC

Risks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs – Neurology (link to abstract – $ for full-text)

Commentaries: Epilepsy drugs linked to higher risk of birth defects, study says – CNN (free) AND Study Confirms Teratogenicity of Valproic Acid, Topiramate – MPR (free)

Related: Guideline: Valproate Use in Women and Girls Of Childbearing Years (free) AND Research: Topiramate Use Early in Pregnancy and the Risk of Oral Clefts (free)

 


Cohort Study: Gabapentinoids linked to Increased Risk of Suicidal Behavior

14 Jun, 2019 | 02:26h | UTC

Associations between gabapentinoids and suicidal behaviour, unintentional overdoses, injuries, road traffic incidents, and violent crime: population based cohort study in Sweden – The BMJ (free)

Editorial: Gabapentinoids linked to new risks, including suicidal behavior (free)

Commentaries: Epilepsy drugs linked to increased risk of suicidal behavior, particularly in young people – The BMJ (free) AND Expert reaction to study on gabapentinoids and risk of suicidal behavior – Science Media Centre (free)

 


Review of Current Guidelines on the Management of Gestational Diabetes Mellitus

14 Jun, 2019 | 02:29h | UTC

Current guidelines on the management of gestational diabetes mellitus: a content analysis and appraisal – BMC Pregnancy and Childbirth (free)

 


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