Family Medicine
AHA Scientific Statement: Measurement of Blood Pressure in Humans
5 Mar, 2019 | 03:13h | UTCNews Release: New scientific statement on blood pressure measurement in people – American Heart Association (free) AND Heart Group Updates Statement on Blood Pressure Measurement – NEJM Journal Watch (free) AND AHA Details Accurate BP Measurement in Updated Scientific Statement – TCTMD (free)
Study: Doctors are Prescribing Antibiotics for Longer than Guidelines Recommend
5 Mar, 2019 | 03:08h | UTCCommentaries: Doctors may be prescribing antibotics for longer than needed – The Conversation (free) AND UK primary care study finds overly long antibiotic courses – CIDRAP (free) AND Antibiotics courses often longer than guidelines – OnMedica (free)
Observational Study Suggests Delaying Antibiotics is Associated with Worse Outcomes in Elderly Patients with UTI
1 Mar, 2019 | 07:17h | UTCCommentaries: Early use of antibiotics in elderly patients with UTIs associated with reduced risk of sepsis – Imperial College London (free) AND Delaying antibiotics in elderly with UTI linked to higher sepsis, death rates – MDedge (free) AND Withholding antibiotics from over-65s may increases cases of deadly sepsis, study shows – The Telegraph (free)
Cochrane Review: Paracetamol Not Much Better Than Placebo for Knee and Hip Osteoarthritis
28 Feb, 2019 | 06:02h | UTCParacetamol versus placebo for knee and hip osteoarthritis – Cochrane Library (free)
Summary: Paracetamol for treating people with hip or knee osteoarthritis – Cochrane Library (free)
Related: Paracetamol: widely used and largely ineffective (free)
Related Commentary on Twitter
New Cochrane Review – 'Paracetamol (acetaminophen) versus placebo for knee and hip osteoarthritis' https://t.co/gGQs23456x @CochraneMSK High‐quality evidence indicated that paracetamol provided only minimal improvements in pain and function for people with hip/knee osteoarthritis
— The Cochrane Library (@CochraneLibrary) February 25, 2019
Alex Nowbar’s Weekly Research Reviews, 26 February 2019
27 Feb, 2019 | 00:55h | UTCAlex Nowbar’s weekly research reviews, 26 February 2019 – The BMJ Opinion (free)
Study: Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults with Nonremitting Depression
27 Feb, 2019 | 00:56h | UTCBenefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Patients Not Fully Responsive to Antidepressants, CBT Alone Found to Improve With Combined Therapies – Psychiatric News Alert (free) AND What to Do When Depression Doesn’t Remit with Monotherapy – NEJM Journal Watch (free for a limited period)
Study: Association of Adolescent Hypertension with Future End-Stage Renal Disease
27 Feb, 2019 | 00:47h | UTCAssociation of Adolescent Hypertension with Future End-Stage Renal Disease – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Adolescent Hypertension Linked to Later End-Stage Renal Disease – NEJM Journal Watch (free)
2018 Update on Pediatric Medical Overuse
27 Feb, 2019 | 00:43h | UTC2018 Update on Pediatric Medical Overuse: A Review – JAMA Pediatrics (free for a limited period)
Related Commentary on Twitter (Thread)
Update on Pediatric Medical Overuse: Top 9 Recent Findings
1. For children with uncomplicated appendicitis, nonoperative treatment with antibiotics could be considered as an initial treatment strategy.https://t.co/qhpWozLMi2 @JAMASurgery @aaronecarroll— JAMA Pediatrics (@JAMAPediatrics) February 18, 2019
Clinical Guidelines on Chronic Rhinosinusitis in Children
26 Feb, 2019 | 02:23h | UTCClinical Guidelines on Chronic Rhinosinusitis in Children – Current Allergy and Asthma Reports (free for a limited period)
Note: if the above link is paywalled, try this one
Related Guideline: Clinical Consensus Statement: Pediatric Chronic Rhinosinusitis – Otolaryngology–Head and Neck Surgery (free)
Meta-analysis: Performance of Fecal Immunochemical Tests for Colorectal Cancer Screening
26 Feb, 2019 | 02:15h | UTCPerformance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Annual noninvasive stool test effective for colon cancer screening – Regenstrief Institute (free) AND Annual FIT home stool test effective for CRC screening rates – American College of Physicians (free) AND Meta-Analysis Adds Support for FIT for Colorectal Cancer Screening – NEJM Journal Watch (free) AND One-Time FIT Adequately Detects CRC but Not Advanced Adenomas – MedPage Today (free registration required)
Consensus Statement: Physical Activity and Ageing
25 Feb, 2019 | 01:19h | UTC
FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Febuxostat
25 Feb, 2019 | 01:15h | UTCCommentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)
Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)
Meta-Analysis: Pharmacological Treatments for Generalized Anxiety Disorder
25 Feb, 2019 | 01:11h | UTCPharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)
Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)
Report: Pharmacotherapy in Older Adults with Cardiovascular Disease
22 Feb, 2019 | 01:38h | UTC
Study: Preventing Misdiagnosis of Diabetes in the Elderly Through Age-dependent HbA1c Reference Intervals
22 Feb, 2019 | 01:36h | UTCCommentary: Should HbA1c cutoffs for DM diagnosis be higher in older adults? – Univadis (free registration required)
Related Commentary on Twitter
HbA1c increases with age in people without diabetes–should there be different cut-points for diagnosis of diabetes in elderly?https://t.co/5FvRXrMBvS@ABCDiab @IntDiabetesFed @DiabetesUK @ADA_DiabetesPro @DiabetesCanada @AmDiabetesAssn @AmarPut @parthaskar @drpatrickholmes
— Kamlesh Khunti (@kamleshkhunti) February 16, 2019
Study: 2-Question Alcohol Screen Can Accurately Characterize Adolescent Risk for Future Alcohol Use Disorders
22 Feb, 2019 | 01:23h | UTCPredictive Validity of a 2-Question Alcohol Screen at 1-, 2-, and 3-Year Follow-up – Pediatrics (free)
Commentaries: Alcohol Use Disorder: A Pediatric-Onset Condition Needing Early Detection and Intervention – Pediatrics (free) AND 2-Question Screen Identifies Adolescents at Risk for Future Alcohol Use Disorders – 2 Minute Medicine (free)
What’s New in the ESC 2018 Guidelines for Arterial hypertension: The Ten Most Important Messages
21 Feb, 2019 | 04:08h | UTCRelated Summaries: Ten Commandments of the 2018 ESC/ESH Hypertension Guidelines (free) AND 2018 ESC/ESH Guidelines for Management of Arterial Hypertension – American College of Cardiology (free)
Original Guideline: ESC/ESH Guidelines for the Management of Arterial Hypertension (free)
Observational Study Suggests Greater Primary Care Physician Supply is Associated with Reduced Mortality
21 Feb, 2019 | 04:04h | UTCAssociation of Primary Care Physician Supply With Population Mortality in the United States, 2005-2015 – JAMA Internal Medicine (free for a limited period)
Commentaries: Primary care physicians associated with longevity, new research finds – Stanford Medicine (free) AND Greater primary care physician supply associated with longer life spans – News Medical (free)
Perspective: Understanding Lung Cancer Screening
21 Feb, 2019 | 03:54h | UTCUnderstanding Lung Cancer Screening – BMJ EBM Spotlight (free)
Consensus: Decision Tree for Diagnosis of Osteoarthritis in Primary Care
21 Feb, 2019 | 03:56h | UTC
USPSTF Draft Statement: BRCA-Related Cancer Risk Assessment, Genetic Counseling, and Genetic Testing
21 Feb, 2019 | 03:59h | UTCDraft Recommendation Statement: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing – U.S. Preventive Services Task Force (free)
Commentaries: USPSTF Issues Draft Recommendation on BRCA Risk Assessment and Testing – NEJM Journal Watch (free) AND New recommendations say not all women need genetic testing for cancer. Critics say it could cost lives – CNN (free)
Ann Robinson’s research reviews – 19 February 2019
20 Feb, 2019 | 03:06h | UTCAnn Robinson’s research reviews, 19 February 2019 – The BMJ Opinion (free)
Study: Fluconazole Linked to Increased Risk of Spontaneous Abortion
20 Feb, 2019 | 02:52h | UTCCommentaries: Risk of Spontaneous Abortion & Birth Defects with Oral Yeast Drug During Pregnancy – MedicalResearch.com (free) AND Common yeast infection pill tied to miscarriages – Reuters (free) AND Oral antifungal drug used to treat yeast infections linked to higher rates of miscarriage – CMAJ (free)
Meta-Analysis: Proton Pump Inhibitors use and Risk of Chronic Kidney Disease
20 Feb, 2019 | 02:48h | UTCRelated Research (just published): Analysis of postmarketing safety data for proton-pump inhibitors reveals increased propensity for renal injury, electrolyte abnormalities, and nephrolithiasis – Scientific Reports (free) and Commentary: Common acid reflux medications linked to increased kidney disease risk – University of California (free)
See also: Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)
Podcast: Psychopharmacology 2.0, Antidepressant Master Class
18 Feb, 2019 | 23:39h | UTC#140 Psychopharmacology 2.0, Antidepressant Master Class – The Curbsiders Internal Medicine Podcast (free)