Family Medicine
Alex Nowbar’s journal reviews—18 July 2019
19 Jul, 2019 | 09:40h | UTCAlex Nowbar’s journal reviews, 18 July 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
[Abstract Only] Observational Study Points to Increased Cardiovascular and Cerebrovascular Risk with Testosterone Replacement Therapy (TRT) in Aging Men
19 Jul, 2019 | 09:37h | UTCCardiovascular and Cerebrovascular Safety of Testosterone Replacement Therapy Among Aging Men with Low Testosterone Levels: A Cohort Study – American Journal of Medicine (link to abstract – $ for full-text)
Commentary: Testosterone replacement therapy (TRT) can increase men’s risk of stroke and heart attack – Elsevier (free)
Meta-Analysis: Menstrual Cup Use, Leakage, Acceptability, Safety, and Availability
18 Jul, 2019 | 10:05h | UTCCommentaries: Inserting informed choice into global menstrual product use and provision – The Lancet Public Health (free) AND Menstrual Cups: Study Finds They’re Safe To Use — And People Like Them – NPR (free) AND Menstrual cups ‘as reliable as tampons’ – BBC (free) AND A Better Way to Manage Your Period? Try the Menstrual Cup, Scientists Say – The New York Times (free)
Guidelines for Moderate Drinking Based on The Presence or Absence of Facial Flushing
17 Jul, 2019 | 09:04h | UTC“individuals with flushing reaction should maintain an alcohol consumption level half of that for non-flushers.”
“Not Initiating is Not the Same Thing as Discontinuing” – Update on Acetylsalicylic Acid for Primary Prevention of Cardiovascular Disease
17 Jul, 2019 | 08:40h | UTCSee also: Acetylsalicylic acid for primary prevention of cardiovascular events – Canadian Family Physician (free)
Related: A Practical Approach to Low-Dose Aspirin for Primary Prevention (free) AND Aspirin for Primary Prevention: Is This the End of the Road? (free) AND Evidence evolving on aspirin as prevention – ACP Internist (free)
Study: Health Lifestyle May Reduce the Incidence of Dementia Even in Patients with High Genetic Risk
16 Jul, 2019 | 09:42h | UTCAssociation of Lifestyle and Genetic Risk With Incidence of Dementia – JAMA (free for a limited period)
Commentaries: Healthy lifestyle reduces dementia risk even in those with genetic risk factors – NHS Choices (free) AND Healthy lifestyle may offset genetic risk of dementia – University of Exeter (free) AND Genes vs. lifestyle: Study ‘undermines fatalistic view of dementia’ – Medical News Today (free) AND Healthy living may help offset genetic risk of dementia: study – Reuters (free) AND Healthy lifestyle may cut risk of dementia regardless of genes – The Guardian (free)
Study: Association of Screen Time and Depression in Adolescence
16 Jul, 2019 | 09:27h | UTCAssociation of Screen Time and Depression in Adolescence – JAMA Pediatrics (free for a limited period)
Commentaries: Expert reaction to a study on screen time and depression in adolescents – Science Media Centre (free) AND Increasing social media use tied to rise in teens’ depressive symptoms, study says – CNN (free)
Clinical Practice: Measles
14 Jul, 2019 | 20:05h | UTCMeasles – New England Journal of Medicine (free)
[Abstract Only] Randomized Trial: Calorie Restriction Reduces Heart and Metabolic Risk Factors
14 Jul, 2019 | 19:55h | UTC2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Moderate calorie restriction in young and middle-aged adults significantly reduces heart and metabolic risk factors independent of weight loss – NIH News Releases (free) AND Cutting calories improves health markers even in slim adults, study reports – Diabetes.co.uk (free) AND Cutting Just 300 Calories Per Day May Keep Your Heart Healthy – NPR (free) AND Cutting about 300 calories a day might benefit your heart, study finds – CNN (free)
Related Commentary on Twitter
Online now: 2 years of #calorie restriction and #cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial https://t.co/RpLfyuNVzN #metabolic syndrome #cardiovascular #hypertension #diabetes #obesity #diet #CVD pic.twitter.com/Ft8YsmQkXj
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) July 12, 2019
Urinary Tract Infections Affect Millions. The Cures Are Faltering.
14 Jul, 2019 | 19:49h | UTCUrinary Tract Infections Affect Millions. The Cures Are Faltering. – The New York Times (10 articles per month are free)
“As the infections become increasingly resistant to antibiotics, some standard treatments no longer work for an ailment that was once easily cured.”
[Abstract Only] Randomized Trial: PPI, H2RA Equally Effective for Prevention of Recurrent Idiopathic Gastroduodenal Ulcer Bleeding
14 Jul, 2019 | 19:03h | UTCPrevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial – Gut (link to abstract – $ for full-text)
Commentary: PPI, H2RA Equally Good at Preventing Bleeding Recurrence in H. Pylori-Negative Ulcers – Medscape (free registration required)
Study: Diagnosis Errors Account for One-third of Severe Harm Malpractice Claims
12 Jul, 2019 | 08:05h | UTCSerious misdiagnosis-related harms in malpractice claims: The “Big Three” – vascular events, infections, and cancers – Diagnosis (free)
Commentary: Diagnosis errors account for one-third of severe harm malpractice claims – Modern Healthcare (free) AND Study: 100k patients injured, die each year after misdiagnosis – UPI (free)
Related Report: Improving Diagnosis in Health Care – The National Academies of Sciences Engineering and Medicine (free)
Interventions to Treat Erectile Dysfunction and Premature Ejaculation: An Overview of Systematic Reviews
12 Jul, 2019 | 07:54h | UTCRelated Guidelines: Erectile Dysfunction: AUA Guideline (free) AND An Update of the International Society of Sexual Medicine’s Guidelines for the Diagnosis and Treatment of Premature Ejaculation – Sexual Medicine (free)
Viewpoint: Preclinical Alzheimer Disease—Early Diagnosis or Overdiagnosis?
12 Jul, 2019 | 07:52h | UTCPreclinical Alzheimer Disease—Early Diagnosis or Overdiagnosis? – JAMA Internal Medicine (free for a limited period)
Related Commentary on Twitter
Preclinical #AlzheimerDisease: may identify high-risk group to target new preventive medications, but may also lead to overdiagnosis and high costs https://t.co/GK3soETwd1
— JAMA Internal Medicine (@JAMAInternalMed) July 9, 2019
Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers
12 Jul, 2019 | 07:44h | UTCCommentaries: No link between flu vaccine in pregnancy and later health problems in children – The BMJ (free) AND Swine flu jab in pregnancy safe for children as well as mothers – OnMedica (free)
[Abstract Only] Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations
11 Jul, 2019 | 11:18h | UTCC-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: CRP Testing Can Safely Reduce Antibiotic Use for COPD Exacerbations – NEJM Journal Watch (free) AND Fingerprick Biomarker Test Can Reduce Use of Antibiotics in COPD Flares – MedicalResearch.com (free)
Drug-induced Endocrinopathies and Diabetes
11 Jul, 2019 | 10:27h | UTC
Ann Robinson’s journal review—10 July 2019
11 Jul, 2019 | 09:59h | UTCAnn Robinson’s journal review, 10 July 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
AAP Clinical Report: Management of Infants at Risk for Group B Streptococcal Disease
10 Jul, 2019 | 10:06h | UTCManagement of Infants at Risk for Group B Streptococcal Disease – Pediatrics (free)
News Releases: AAP Updates Guidance on Preventing, Managing Infants with Group B Strep Disease – American Academy of Pediatrics (free) AND Early-onset group B strep: New guidance includes changes in dosing, assessment – AAP News (free)
Related: ACOG Guideline: Prevention of Early-Onset Group B Streptococcal Disease in Newborns (free)
Review: Subclinical Hypothyroidism
10 Jul, 2019 | 02:36h | UTCSubclinical Hypothyroidism – A Review – JAMA (free link for a limited period)
Related: BMJ Guideline: Treatment of Subclinical Hypothyroidism (free guideline and commentaries)
[Abstract Only] Little Evidence for Nutritional Supplements to Improve Cardiovascular Outcomes
9 Jul, 2019 | 10:19h | UTCEffects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Little evidence supports nutritional supplements for protection against cardiovascular disease, death – ACP Internist (free) AND Nutritional supplements and diets not always protective, WVU research suggests – West Virginia University (free) AND Supplements and Diets for Heart Health Show Limited Proof of Benefit – The New York Times (10 articles per month are free)
Related Study: Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free) AND Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)
Guideline for the Antibiotic Use in Acute Gastroenteritis
8 Jul, 2019 | 10:18h | UTCGuideline for the Antibiotic Use in Acute Gastroenteritis – Infection & Chemotherapy (free)
Related: ACG Clinical Guideline: Diagnosis, Treatment, and Prevention of Acute Diarrheal Infections in Adults – American Journal of Gastroenterology (free)
Viewpoint: Advances in Understanding the Pathophysiology of Chronic Fatigue Syndrome
8 Jul, 2019 | 10:17h | UTCAdvances in Understanding the Pathophysiology of Chronic Fatigue Syndrome – JAMA (free for a limited period)
[Abstract Only] Study: Directly Observed Therapy May Identify Nonadherence in Patients with Apparent Treatment-Resistant Hypertension
8 Jul, 2019 | 10:03h | UTCUse of Directly Observed Therapy to Assess Treatment Adherence in Patients With Apparent Treatment-Resistant Hypertension – JAMA Internal Medicine (free link for a limited period)
Commentaries: Directly Observed Therapy Effective for Treatment-Resistant Hypertension – Clinical Advisor (free) AND Think it’s treatment-resistant hypertension? Your eyes need to DOT (directly observe therapy) – Univadis (free registration required)
Related Commentary on Twitter
Nonadherence to BP-lowering drug regimens is high among referred patients with apparent treatment-resistant hypertension https://t.co/BTzKLTuYwi
— JAMA Internal Medicine (@JAMAInternalMed) June 22, 2019
[Abstract Only] Study: Exposure to Antidepressant Medication and the Risk of Incident Dementia
8 Jul, 2019 | 09:53h | UTCExposure to Antidepressant Medication and the Risk of Incident Dementia – The American Journal of Geriatric Psychiatry (link to abstract – $ for full-text)
Commentaries: Antidepressants in old age may increase risk of dementia, Israeli study finds – The Times of Israel (free) AND Antidepressant use in older age is linked to increased dementia risk – Univadis (free registration required)