Family Medicine
Review: Vaccines for International Travel
4 Nov, 2019 | 00:28h | UTCVaccines for International Travel – Mayo Clinic Proceedings (free)
See also: Just Released. 2020 Edition of CDC Traveler’s Health Yellow Book (free resources)
AAP Policy Statement: The Use of Nonnutritive Sweeteners in Children
3 Nov, 2019 | 20:15h | UTCThe Use of Nonnutritive Sweeteners in Children – Pediatrics (free)
News Release: Nonnutritive sweetener use in children – American Academy of Pediatrics (free)
Commentary: AAP: Too Much Unknown About Sugar Substitutes’ Effects on Kids – MedPage Today (free registration required)
Pay for Relationship: A Novel Solution to the Primary Care Crisis
3 Nov, 2019 | 19:53h | UTCPay for Relationship: A Novel Solution to the Primary Care Crisis – NEJM Catalyst (free)
Randomized Trial: Severe Energy Restriction Associated with Increased Bone Loss when Compared with Moderate Energy Restriction
3 Nov, 2019 | 19:48h | UTCCommentary: Total Meal Replacement Diets Effective for Weight Loss, But Can Lead To Bone Loss – MedicalResearch.com (free)
Research: Measles Virus Infection Diminishes Preexisting Antibodies that Offer Protection from Other Pathogens
1 Nov, 2019 | 08:45h | UTCMeasles virus infection diminishes preexisting antibodies that offer protection from other pathogens – Science (free for a limited period)
Related Research: Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles – Science Immunology (free for a limited period)
Commentaries: How measles infections can wipe away immunity to other diseases – STAT (free) AND Measles wipe immune system’s memory of other illnesses, studies find – CNN (free) AND Measles Virus May Wipe Out Immune Protection For Other Diseases – NPR (free) AND Measles vaccines protect against more than just measles. Here’s how. – National Geographic (free) AND Measles Infection Could Leave Kids Vulnerable to Other Diseases – Scientific American (free)
Related Commentary on Twitter
The measles infection can cripple long-term immunity against viruses and bacteria, creating a kind of “immune amnesia” that leaves individuals more vulnerable to future infections by other pathogens, according to two studies:
▶ https://t.co/te7kr7N7Ju
▶ https://t.co/tiSTrvyQob pic.twitter.com/taaN3KIMPk— Science Magazine (@ScienceMagazine) October 31, 2019
Meta-Analysis: Calcium Supplementation May Increase the Risk of Myocardial Infarction
1 Nov, 2019 | 07:42h | UTCRelated Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)
See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)
Systematic Review: Antiplatelet Agents for Preventing Pre‐eclampsia and its Complications
1 Nov, 2019 | 07:54h | UTCAntiplatelet agents for preventing pre‐eclampsia and its complications – Cochrane Library (free)
Summary: Antiplatelet agents for preventing pre-eclampsia and its complications – Cochrane Library (free)
Related Randomized Trial: Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia – New England Journal of Medicine (free study and commentaries)
Study: Treatment of Subclinical Hypothyroidism Not Beneficial for Elderly Patients
31 Oct, 2019 | 08:42h | UTCAssociation Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism – JAMA (free for a limited period)
Editorial: The Thyrotropin Reference Range Should Be Changed in Older Patients (free for a limited period)
Related Review: Subclinical Hypothyroidism – JAMA (free for a limited period)
Related Randomized Trial: Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism – New England Journal of Medicine (free)
Related Commentary on Twitter
Important RCT data demonstrating that routine treatment with levothyroxine for subclinical hypothyroidism in adults aged 80 years and older was not associated with improved patient-reported quality of life outcome scores for hypothyroid symptoms https://t.co/KboKmMFcxm
— Joseph Ross (@jsross119) October 30, 2019
Study: In Utero Acetaminophen Exposure Linked to Increased Risk of ADHD and Autism Spectrum Disorder in Childhood
31 Oct, 2019 | 08:12h | UTCAssociation of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood – JAMA Psychiatry (free for a limited period)
Commentaries: NIH-funded study suggests acetaminophen exposure in pregnancy linked to higher risk of ADHD, autism – NIH News Releases (free) AND Babies at higher risk for ADHD, autism if pregnant moms took acetaminophen – Reuters (free) AND Expert reaction to study looking at paracetamol in pregnancy and autism, ADHD and other developmental disabilities in children – Science Media Centre (free)
Related Studies: Cohort Study: Associations Between Paracetamol Intake Between 18 and 32 Weeks Gestation and Neurocognitive Outcomes in the Child (free) AND Meta-Analysis: Prenatal Exposure to Acetaminophen and Risk for ADHD and Autistic Spectrum Disorder (free) AND Prenatal Exposure to Acetaminophen and Risk of ADHD (free)
[Abstract Only] Cohort Study: Mortality-related Health Metrics Associated with Mental Disorders
29 Oct, 2019 | 10:33h | UTCA comprehensive analysis of mortality-related health metrics associated with mental disorders: a nationwide, register-based cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Life expectancy mapped for people with mental disorders – The University of Queensland (free) AND Mentally ill die many years earlier than others – Aarhus University (free)
Related Commentary on Twitter (Thread – Click for More)
https://twitter.com/oleguerplana/status/1187497468105089024?s=03
[Abstract Only] Meta-Analysis: Insufficient Evidence for The Use of Cannabinoids for Treating Mental Disorders
29 Oct, 2019 | 10:24h | UTCCannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentaries: Marijuana Cannabinoids Don’t Help With Depression, Anxiety, ADHS, Tourettes, Psychosis, Or PTSD – Scientific Blogging (free) AND There is little evidence that cannabis helps mental health problems – NewScientist (free) AND There’s ‘Scarce Evidence’ to Suggest Cannabis Improves Mental Health Symptoms, a New Research Review Says – TIME (free) AND Medicinal cannabis not proven in mental health, study finds – Reuters (free) AND Risks of cannabis use for mental health treatment outweigh benefits – The Guardian (free)
Related Commentary on Twitter
NEW—Insufficient evidence that medicinal #cannabinoids improve #mentalhealth: finding from a systematic review and meta-analysis combining 83 studies including 3000 people @TheLancetPsych https://t.co/dD7czOHA7O pic.twitter.com/tvsDCqcnfa
— The Lancet (@TheLancet) October 28, 2019
AAP Policy Statement: Pediatric Metabolic and Bariatric Surgery
28 Oct, 2019 | 00:48h | UTCPediatric Metabolic and Bariatric Surgery: Evidence, Barriers, and Best Practices – Pediatrics (free)
Technical Report: Metabolic and Bariatric Surgery for Pediatric Patients With Severe Obesity – Pediatrics (free)
Commentary: More kids should get weight-loss surgery, even some preteens, pediatricians say – STAT / Associated Press (free)
Interest in Cannabidiol Products Keeps Soaring Despite Limited Evidence in Humans
27 Oct, 2019 | 19:29h | UTCTrends in Internet Searches for Cannabidiol (CBD) in the United States – JAMA Network Open (free)
Commentaries: Interest in CBD products keeps soaring, but health experts wary – HealthDay (free) AND Online Searches For CBD Skyrocket – MedicalResearch.com (free)
Related Commentary on Twitter
"Interest in CBD products keeps soaring, but health experts wary" https://t.co/TP50a31bbP via @medical_xpress
"At this time there are no known benefits for taking CBD over-the-counter. #CBD is this generation's snake oil…"
Studies "in humans are still limited…"#CBDHype.
— Timothy Caulfield (@CaulfieldTim) October 25, 2019
Report: Safe Ambulatory Care, Strategies for Patient Safety and Risk Reduction
27 Oct, 2019 | 23:33h | UTCNews Release: ECRI Institute: Diagnostic Tests, Medication Pose Biggest Risks to Patients in Ambulatory Care (free)
Commentaries: ECRI Institute: Top 4 Biggest Risks in Ambulatory Care to Watch – HIT Consultant Media (free) AND Top 5 Patient Safety Risks in Ambulatory Care – Medscape (free registration required)
[Abstract Only] Large Observational Analysis Suggests Thiazide Diuretics are Superior as First-Line Drugs for the Treatment of Hypertension
25 Oct, 2019 | 08:48h | UTCComprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis – The Lancet (link to abstract – $ for full-text)
Commentaries: Most Prescribed Blood Pressure Drugs May Be Less Effective than Others – Columbia University Irving Medical Center (free) AND Diuretics Better Than ACE Inhibitors as Initial Hypertension Treatment, Analysis Suggests – NEJM Journal Watch (free)
Related Cochrane Review: Thiazides best first choice for hypertension (free)
Perspective: The Silent Heart Attack You Didn’t Know You Had
25 Oct, 2019 | 08:38h | UTCThe Silent Heart Attack You Didn’t Know You Had – The New York Times (10 articles per month are free)
Related Studies: Silent Myocardial Infarction Often Precedes Sudden Cardiac Death (link to abstract and commentaries) AND Cohort Study: Long-term Outcomes of Unrecognized MI (link to abstract and commentaries)
A State-of-the-Art Review Highlighting Medical Overuse in Dermatology, 2017-2018
24 Oct, 2019 | 08:46h | UTCA State-of-the-Art Review Highlighting Medical Overuse in Dermatology, 2017-2018: A Systematic Review – JAMA Dermatology (free for a limited period)
Study: Prevalence and Factors Associated with Safe Infant Sleep Practices
24 Oct, 2019 | 08:45h | UTCPrevalence and Factors Associated with Safe Infant Sleep Practices – Pediatrics (free)
Commentaries: Doctors still need to tell parents about safe infant sleep practices – Reuters (free) AND Safe infant sleep practices remain underutilized – 2 Minute Medicine (free)
Review: Diagnosis and Management of Dementia
24 Oct, 2019 | 08:42h | UTCDiagnosis and Management of Dementia: Review – JAMA (free for a limited period)
The 2018 ESC/ESH Hypertension Guideline and the 2019 NICE Hypertension Guideline, How and Why they Differ
24 Oct, 2019 | 08:37h | UTCOriginal Guidelines: 2018 ESC/ESH Guidelines for the management of arterial hypertension – European Heart Journal (free) AND Hypertension in adults: diagnosis and management – National Institute for Health and Care Excellence (free)
[Abstract Only] Cohort Study: Eating Trans-fat May Increase the Risk of Dementia
24 Oct, 2019 | 07:41h | UTCSerum elaidic acid concentration and risk of dementia: The Hisayama study – Neurology (link to abstract – $ for full-text)
Commentaries: Alzheimer’s risk may be 75% higher for people who eat trans fats – CNN (free) AND Trans Fats, Bad for the Heart, May Be Bad for the Brain as Well – The New York Times (10 articles per month are free)
Study: Stress Related Disorders Linked to Subsequent Risk of Life-Threatening Infections
24 Oct, 2019 | 07:33h | UTCEditorial: Stress related disorders and physical health (free)
Commentary: Stress-related disorders linked to subsequent risk of severe infections – British Medical Journal (free)
Study: Heavier Social Media Use Associated with Poorer Sleep Patterns
24 Oct, 2019 | 07:22h | UTCCommentaries: More LOLs, Fewer Zzzs: Teens May Be Losing Sleep Over Social Media – NPR (free) AND High social media use linked to poor sleep in teens – OnMedica (free) AND Heavy social media use linked to poor sleep – BBC (free)
Ann Robinson’s journal review—23 October 2019
24 Oct, 2019 | 07:25h | UTCAnn Robinson’s journal review, 23 October 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
[Abstract Only] Practice Changing? – Bedtime Hypertension Treatment Improves Cardiovascular Risk Reduction in Randomized Trial
23 Oct, 2019 | 08:23h | UTCBedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial – European Heart Journal (link to abstract – $ for full-text)
Commentaries: Blood pressure pills ‘work better at bedtime’ – BBC (free) AND You might want to change the time of day you take your blood pressure medicine – CNN (free) AND Expert reaction to study looking at the time of day when blood pressure medication is taken and cardiovascular disease risk – Science Media Centre (free)


