Family Medicine
Study: Testosterone Therapy Linked to Increased Risk of Venous Thromboembolism Among Men with and Without Hypogonadism
12 Nov, 2019 | 11:22h | UTCAssociation of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism – JAMA Internal Medicine (free for a limited period)
Related Commentary on Twitter
Using testosterone therapy in 6-month case period associated with doubling of VTE risk for men both with and without clinical hypogonadism. https://t.co/rosKWgWgBS
— JAMA Internal Medicine (@JAMAInternalMed) November 11, 2019
Meta-Analysis: Aspirin for Primary Prevention of Cardiovascular Disease with a Particular Focus on Subgroups
12 Nov, 2019 | 11:19h | UTCRelated: Acetylsalicylic acid for primary prevention of cardiovascular events – Canadian Family Physician (free) AND Evidence evolving on aspirin as prevention – ACP Internist (free) AND Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Disease – Annals of Internal Medicine (link to abstract and commentaries) AND Aspirin for Primary Prevention: Is This the End of the Road? (selection of resources on the subject)
Meta-Analysis: Nutrient Supplements Reduce Child Mortality in Low- and Middle-income Countries
12 Nov, 2019 | 11:17h | UTCCommentaries: Nutrient supplements significantly reduce child deaths – University of California (free) AND Children receiving small-quantity lipid-based nutrient supplementary foods have lower mortality rates – American Society for Nutrition (free)
Review: Sleep-Related Disorders in Neurology and Psychiatry
12 Nov, 2019 | 11:16h | UTCSleep-Related Disorders in Neurology and Psychiatry – Deutsches Ärzteblatt international (free)
#ACR19 – [Not Published Yet] Meta-Analysis: For People with Osteoarthritis, Opioids Offer Minor Pain Relief and Function Benefits, but No Quality of Life Benefit
12 Nov, 2019 | 10:48h | UTCAbstract: Is There Any Role for Opioids in the Management of OA? (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
#KidneyWk – Randomized Trial: Vitamin D and Omega-3 Fatty Acids Do Not Preserve Kidney Function in Patients with Type 2 Diabetes
10 Nov, 2019 | 14:36h | UTCEffect of Vitamin D and Omega-3 Fatty Acid Supplementation on Kidney Function in Patients With Type 2 Diabetes: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Vitamin D and Health Outcomes: Then Came the Randomized Clinical Trials – JAMA (free for a limited period)
Commentary: Supplements don’t preserve kidney health in Type 2 diabetes – University of Washington School of Medicine (free)
#KidneyWk – Just presented at the American Society of Nephrology Kidney Week 2019
Related Commentary on Twitter
Study findings do not support the use of #vitaminD or #omega3 fatty acid supplementation for preserving kidney function in adults with #type2diabetes https://t.co/ppUnvwMXRR #KidneyWk
— JAMA (@JAMA_current) November 9, 2019
#KidneyWk – Study: Development of a Risk Prediction Calculator for Incident Chronic Kidney Disease
10 Nov, 2019 | 14:39h | UTCDevelopment of Risk Prediction Equations for Incident Chronic Kidney Disease – JAMA (free for a limited period)
See Calculator: Risk of Developing Reduced Kidney Function (free tool)
Editorial: Predicting Risk of Kidney Disease: Is Risk-Based Kidney Care on the Horizon? – JAMA (free for a limited period)
Commentaries: New Tool Predicts Five-Year Risk of Chronic Kidney Disease With High Accuracy – Johns Hopkins Bloomberg School of Public Health (free) AND Researchers Develop Tool to Identify Those at Risk of Future CKD – AJMC (free)
#KidneyWk – Just presented at the American Society of Nephrology Kidney Week 2019
Related Commentary on Twitter
Equations for predicting risk of incident #CKD were developed from more than 5 million individuals from 34 multinational cohorts and demonstrated high discrimination and variable calibration in diverse populations https://t.co/7uNRpv4m3Y #KidneyWk
— JAMA (@JAMA_current) November 8, 2019
Updated Cardiovascular Prevention Guideline of the Brazilian Society of Cardiology – 2019
10 Nov, 2019 | 13:59h | UTCRelated Guidelines: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free guideline and resources) AND Cardiovascular disease: risk assessment and reduction, including lipid modification – National Institute for Health and Care Excellence (free) AND Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2018 update – Canadian Medical Association Journal (free)
Podcast: Management of Multimorbidity
10 Nov, 2019 | 13:55h | UTC#181 The Multimorbidity Games with Josh Uy MD – The Curbsiders Internal Medicine Podcast (free text and audio)
See also: Episode List
Related: Multimorbidity: clinical assessment and management – NICE Guideline (free) AND Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology (free) AND Effectiveness of interventions for managing multiple high-burden chronic diseases in older adults: a systematic review and meta-analysis – Canadian Medical Association Journal (free) AND Multimorbidity: a priority for global health research – The Academy of Medical Sciences (free)
Guideline Summary: Obesity Hypoventilation Syndrome
10 Nov, 2019 | 13:11h | UTCNew guidelines on obesity hypoventilation syndrome released – PulmCCM (free)
Original Article: ATS Guideline: Evaluation and Management of Obesity Hypoventilation Syndrome (free article and news release)
Cardiovascular Risk of Electronic Cigarettes: A Review of Preclinical and Clinical Studies
8 Nov, 2019 | 08:22h | UTCCommentaries: Vaping not worth potential heart risk, researchers say – Ohio State University (free) AND Vaping risks significant, says new review – News Medical (free) AND E-cigs may damage the heart, study says – MedicalXpress (free)
Ann Robinson’s journal review—7 November 2019
8 Nov, 2019 | 07:15h | UTCAnn Robinson’s journal review, 7 November 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
Study: Association Between Gifts from Pharmaceutical Companies to Doctors and Their Drug Prescribing Patterns
7 Nov, 2019 | 08:07h | UTC
Related Commentary on Twitter
New study shows that gifts to GPs are common and associated with less rational drug prescriptions for patients and more expenses for the National Health Insurance https://t.co/Hvu6BqrHhi
— The BMJ (@bmj_latest) November 6, 2019
Cohort Study: Metformin Use Linked to Lower Risk of Hospitalization for Heart Failure in Patients with Type 2 Diabetes
7 Nov, 2019 | 07:40h | UTCCommentary: Metformin lowers risk of HF hospitalization in those with T2D – Cardiovascular Business (free)
Related Study: Metformin Use Linked to Reduced Risk for Cardiovascular Death and All-cause Mortality (link to abstract and commentaries)
Study: Screen Time Linked to Changes in Brain White Matter Integrity in Preschool-Aged Children
7 Nov, 2019 | 08:00h | UTCAssociations Between Screen-Based Media Use and Brain White Matter Integrity in Preschool-Aged Children – JAMA Pediatrics (free for a limited period)
Commentaries: Expert reaction to study on screen use and white brain matter in children – Science Media Centre (free) AND Preschoolers’ Screen Time Tied to Brain Structure Irregularities – MedPage Today (free registration required)
Related: Meta-Analysis: Association Between Screen Media Use and Academic Performance Among Children and Adolescents (link to abstract and commentaries)
Update on the Management of Constipation
7 Nov, 2019 | 07:35h | UTCUpdate on the Management of Constipation – JAMA (free for a limited period)
Related: Indian Consensus on Chronic Constipation in Adults (free guidelines and reviews on the subject)
Randomized Trial: Internet Based Vestibular Rehabilitation for Adults with a Chronic Vestibular Syndrome
6 Nov, 2019 | 08:35h | UTCCommentaries: Treat dizziness and vertigo with vestibular rehabilitation – The BMJ Opinion (free) AND Online Intervention Could Help Those with Chronic Vestibular Syndrome – NEJM Journal Watch (free)
Related Study: Internet-Based Vestibular Rehabilitation for Older Adults With Chronic Dizziness (free study and commentaries)
State of the Art Review: Benefits and Harms of Intensive Glycemic Control in Patients with Type 2 Diabetes
6 Nov, 2019 | 08:37h | UTCBenefits and harms of intensive glycemic control in patients with type 2 diabetes – The BMJ (free for a limited period)
Related Commentary on Twitter
Evidence over the past decade has shown that the aggressive efforts often needed to achieve low HbA1c levels can lead to worse clinical outcomes. This review provides a summary of the evidence on the benefits and harms of intensive glycemic control https://t.co/rghp5iVRfX
— The BMJ (@bmj_latest) November 5, 2019
Meta-Analysis: Mind-Body Therapies for Opioid-Treated Pain
6 Nov, 2019 | 08:10h | UTCMind-Body Therapies for Opioid-Treated Pain: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentaries: Study highlights role of mind-body therapies in addressing opioid-treated pain – News Medical (free) AND Meditation, Mindfulness Hold Promise for Pain Treatment, Curbing Opioid Use – U.S. News (free)
ACP Guideline: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults
5 Nov, 2019 | 10:43h | UTCNews Release: ACP issues guidance for colorectal cancer screening – American College of Physicians (free)
Summaries for Patients: Colorectal Cancer Screening in Average-Risk Adults (free)
Commentaries: ACP issues new guidance on colorectal cancer screening – ACP Internist (free) AND Medical groups differ on when to start colon and rectal cancer screening. Here’s why – CNN (free)
Related: BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy (new guideline suggesting a more selective approach to screening) AND Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society (recent guideline with recommendation to start screening at 45 years, with links to guidelines from other organizations)
Choosing Wisely in Family Medicine: Thirteen Things Physicians and Patients Should Question
5 Nov, 2019 | 08:32h | UTCThirteen Things Physicians and Patients Should Question – Choosing Wisely Canada (free)
Related: American Academy of Family Physicians: Twenty Things Physicians and Patients Should Question (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
[Abstract Only] Meta-Analysis: Fish Oil Supplements Have no Effect on Anxiety and Depression
5 Nov, 2019 | 08:13h | UTCOmega-3 and polyunsaturated fat for prevention of depression and anxiety symptoms: systematic review and meta-analysis of randomised trials – British Journal of Psychiatry (link to abstract – $ for full-text)
News Release: Fish oil supplements have no effect on anxiety and depression – University of East Anglia (free)
Meta-Analysis: Which Modes of Exercise are Most Effective for Treating Low Back Pain?
4 Nov, 2019 | 01:19h | UTC
Related Commentary on Twitter
Hot off the press 🔥🔓🔥
Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis
👀👀👇👇https://t.co/MTLlPbew6Z pic.twitter.com/wiOK4ukyig
— Physio Meets Science (@PhysioMeScience) October 30, 2019
Randomized Trial: Naproxen vs. Colchicine for the Treatment of Gout Flares in Primary Care
4 Nov, 2019 | 01:13h | UTC
Related Commentary on Twitter
Our @NIHRSPCR funded research finds no diff in pain between people with a #goutflare randomised to either #naproxen or low-dose #colchicine, but #naproxen caused fewer #sideeffects, supporting its use as first-line treatment for #flares in #primarycare https://t.co/cKBDymlFjS
— Inflam Arthr Keele (@KeeleInflamArth) November 1, 2019
Alex Nowbar’s weekly review—1 November 2019
4 Nov, 2019 | 00:41h | UTCAlex Nowbar’s weekly review, 1 November 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.


