Family Medicine
NICE Guideline: Management of Thyroid Disease
21 Nov, 2019 | 10:39h | UTCThyroid disease: assessment and management – National Institute for Health and Care Excellence (free)
Randomized Trial: Induction of Labor at 41 Weeks vs. Expectant Management and Induction of Labor at 42 Weeks
21 Nov, 2019 | 10:23h | UTCEditorial: When to induce late term pregnancies (free)
Related: Randomized Trial: Induction of Labor at 41 Weeks vs. Expectant Management Until 42 Weeks (free) AND WHO Recommendations: Induction of Labor at or Beyond Term (free) AND Cochrane Review: Induction of Labor for Improving Birth Outcomes for Women at or Beyond Term (free)
Related Commentary on Twitter
Inducing labour at 41 weeks in low risk pregnancies is associated with a lower risk of newborn death compared with expectant management (a “wait and see” approach) until 42 weeks, suggests a trial published by @bmj_latest this week https://t.co/SGSHRcMjy1 https://t.co/bInvNdMZdW pic.twitter.com/BScVqjMPnd
— BMJ Group (@bmj_company) November 21, 2019
High-protein Diet is Bad for Kidney Health: Unleashing the Taboo
21 Nov, 2019 | 08:29h | UTCRelated: Dietary protein intake and kidney function decline after myocardial infarction: the Alpha Omega Cohort – Nephrology Dialysis Transplantation (free) AND High-protein diet with renal hyperfiltration is associated with rapid decline rate of renal function: a community-based prospective cohort study – Nephrology Dialysis Transplantation (link to abstract – $ for full-text) AND Dietary Protein Intake and Chronic Kidney Disease – Current Opinion in Clinical Nutrition & Metabolic Care (free)
Perspective: Cannabidiol Products Are Everywhere, but Should People Be Using Them?
21 Nov, 2019 | 08:16h | UTCCannabidiol Products Are Everywhere, but Should People Be Using Them? – JAMA (free for a limited period)
Related: NICE Guideline: Cannabis-Based Medicinal Products (free Guideline and other resources)
NICE Guideline: Fever in Under 5s
20 Nov, 2019 | 10:49h | UTC
Study: Switching from Tobacco Cigarettes to Electronic Cigarettes May Improve Cardiovascular Health
20 Nov, 2019 | 10:31h | UTCCommentaries: Smokers who switch to vaping could soon ‘have healthier hearts’ – NHS Choices (free) AND Vaping less harmful than smoking for vascular health, major study finds – University of Dundee (free) AND Switching from cigarettes to vapes may be better for heart health, study says – CNN (free)
Canadian Task Force Recommendation: Don’t Screen Asymptomatic Patients for Thyroid Dysfunction
19 Nov, 2019 | 10:17h | UTCNews Release: Screening for thyroid dysfunction in people without symptoms: Don’t routinely check that box – Canadian Medical Association Journal (free)
See also: Asymptomatic Thyroid Dysfunction (2019): Summary of recommendations for clinicians and policy-makers – Canadian Task Force on Preventive Health Care (free resources) AND Infographic (free PDF)
Related Commentary on Twitter
Should asymptomatic patients be screened for thyroid disease? The Canadian Task Force on Preventive Health Care says no: https://t.co/RLjRQwHsUX @cantaskforce #primarycare pic.twitter.com/CsBDvUQ2Po
— CMAJ (@CMAJ) November 18, 2019
Guideline: Treatment of Drug-Resistant Tuberculosis
19 Nov, 2019 | 10:32h | UTCNews Release: New clinical guideline for the treatment and prevention of drug-resistant tuberculosis – American Thoracic Society (free)
Related: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free guideline and commentary) AND Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment (free article and commentaries) AND The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis (free registration required)
This Week is World Antibiotic Awareness Week! – See Practical Resources
19 Nov, 2019 | 09:55h | UTC– Using Antibiotics Wisely in Primary Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Long-Term Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Hospitals – Choosing Wisely Canada (free)
– NICE Antimicrobial prescribing guidelines (resource covering many common conditions)
– NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
Cohort Study: Association of Premature Natural and Surgical Menopause with Incident Cardiovascular Disease
19 Nov, 2019 | 08:01h | UTCAssociation of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease – JAMA (free for a limited period)
Review: Preoperative Evaluation Before Noncardiac Surgery
19 Nov, 2019 | 07:56h | UTCPreoperative Evaluation Before Noncardiac Surgery – Mayo Clinic Proceedings (free)
Related: Guideline: Preoperative Evaluation of Adult Patients Before Elective, Noncardiothoracic Surgery (free guidelines on the subject)
Review: Coronary Microvascular Dysfunction Causing Cardiac Ischemia in Women
19 Nov, 2019 | 07:41h | UTCCoronary Microvascular Dysfunction Causing Cardiac Ischemia in Women – JAMA (free for a limited period)
Related: Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries (study, guidelines, and reviews on the subject)
Related Commentary on Twitter
2/3 of women with symptoms and signs of ischemia have no evidence of obstructive coronary artery disease (#INOCA). Many have coronary microvascular dysfunction, diagnosed by finding reduced coronary flow reserve on pharmacologic stress testing https://t.co/yNIFDVwNOm #AHA19
— JAMA (@JAMA_current) November 19, 2019
Review: HIV Preexposure Prophylaxis—The Role of Primary Care Clinicians in Ending the HIV Epidemic
19 Nov, 2019 | 07:38h | UTCHIV Preexposure Prophylaxis—The Role of Primary Care Clinicians in Ending the HIV Epidemic – JAMA Internal Medicine (free for a limited period)
Related: USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection (free) AND British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject)
SEEDS for Success: Lifestyle Management in Migraine
18 Nov, 2019 | 00:25h | UTCSEEDS for success: Lifestyle management in migraine – Cleveland Clinic Journal of Medicine (free)
Position Statement: Vegetarian Diets in Childhood and Adolescence
15 Nov, 2019 | 10:44h | UTCVegetarian diets in childhood and adolescence – Molecular and Cellular Pediatrics (free)
Meta-Analysis: Comparative Efficacy and Safety of New Surgical Treatments for Benign Prostatic Hyperplasia
15 Nov, 2019 | 10:36h | UTC
Meta-Analysis: Outcomes at Follow-up of Negative Colonoscopy in Average Risk Population
15 Nov, 2019 | 10:25h | UTCRelated Guidelines: ACP Guideline: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults (free) AND BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy (new guideline suggesting a more selective approach to screening) AND Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society (recent guideline with recommendation to start screening at 45 years, with links to guidelines from other organizations)
“Our findings suggest that 10 year intervals for colonoscopy screening after a negative colonoscopy, as currently recommended, may be adequate”
Alex Nowbar’s weekly review—15 November 2019
15 Nov, 2019 | 10:11h | UTCAlex Nowbar’s weekly review, 15 November 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
[Abstract Only] Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation
14 Nov, 2019 | 10:37h | UTCLarge-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: What Can We Learn From The Apple Heart Study? – Cardiobrief (free)
“…nearly half a million people were required to identify a few hundred people with AF. (It should further be noted that we have no idea whether the patients identified in this group will even benefit from their diagnosis, since they may differ in important ways from AF patients identified by traditional means.)” (from Cardiobrief)
[Abstract Only] Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children
14 Nov, 2019 | 10:22h | UTCAntibiotic Treatment and Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children: A Systematic Review and Meta-analysis – Annals of Surgery (link to abstract – $ for full-text)
Related Meta-Analysis: Antibiotic therapy for acute uncomplicated appendicitis: a systematic review and meta-analysis – International Journal of Colorectal Disease (free) AND Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (link to abstract and commentaries) AND Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis (free study and commentaries)
Related Randomized Trials: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (free study and commentaries) AND Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis (link to abstract and commentaries)
Related Cohort Study: Study: Nonoperative Management of Uncomplicated Appendicitis (free study and commentary)
Cohort Study: Even Minor Surgical Procedures Are Associated with High Risk for Patients with Frailty
14 Nov, 2019 | 10:19h | UTCAssociation of Preoperative Patient Frailty and Operative Stress With Postoperative Mortality – JAMA Surgery (free for a limited period)
Commentaries: Looking Beyond Mortality Among Older Adults Who Are Frail and Considering Surgical Intervention – JAMA Surgery (free for a limited period) AND No such thing as a low-risk surgery for frail patients – Vanderbilt University Medical Center (free) AND Even low-stress surgery can be fatal for frail patients, study finds – University of Texas Health Center at San Antonio (free)
STI Update: Testing, Treatment, and Emerging Threats
13 Nov, 2019 | 10:42h | UTCSTI update: Testing, treatment, and emerging threats – Cleveland Clinic Journal of Medicine (free)
Guideline Summary: Drugs for Atrial Fibrillation
13 Nov, 2019 | 10:36h | UTCDrugs for Atrial Fibrillation – JAMA (free for a limited period)
Podcast: Review of Atrial Fibrillation Treatment – JAMA (free audio)
Original Guideline: 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation (free)
NICE Guideline: Cannabis-Based Medicinal Products
12 Nov, 2019 | 11:27h | UTCCannabis-based medicinal products – National Institute for Health and Care Excellence (free)
Commentaries: Drug experts on the new guidance for medicinal cannabis – The Conversation (free) AND Ian Hamilton: New guidelines for prescribing medicinal cannabis—another dashed hope for patients – The BMJ Opinion (free)
Related: Guideline for Prescribing Medical Cannabinoids in Primary Care – Canadian Family Physician (free) AND Cannabinoids for Chronic Pain – Therapeutics Initiative AND (free) Meta-Analysis: Insufficient Evidence for The Use of Cannabinoids for Treating Mental Disorders – The Lancet Psychiatry (link to abstract and commentaries) AND The Effects of Cannabis Among Adults With Chronic Pain – Annals of Internal Medicine (link to abstract and commentaries)
“In short, NICE has concluded that more research is needed before it can recommend the use of cannabis-based products for medicinal use.” (from The Conversation)
#ACR19 – Randomized Trial: Low-Dose Corticosteroids for Short Periods Effective and Safe for Hand Osteoarthritis
12 Nov, 2019 | 11:23h | UTCResults of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)
Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting