Family Medicine
Alex Nowbar’s weekly review—29 November 2019
1 Dec, 2019 | 22:00h | UTCAlex Nowbar’s weekly review, 29 November 2019 – The BMJ Opinion (free)
Study: Association of Mild Hearing Loss with Behavioral Problems and School Performance in Children
1 Dec, 2019 | 21:58h | UTCAssociation of Slight to Mild Hearing Loss with Behavioral Problems and School Performance in Children – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
Commentaries: When Slight Degrees of Hearing Impairment in Children May Actually Matter – JAMA Otolaryngology-Head & Neck Surgery (free) AND Impact of Mild Hearing Loss on Childhood Behavior And School Performance – MedicalResearch.com (free)
Meta-Analysis: Prevalence of Problematic Smartphone Usage and Associated Mental Health Outcomes Amongst Children and Young People
1 Dec, 2019 | 21:56h | UTCCommentaries: An estimated 1 in 4 children and young people have problematic smartphone usage – King’s College London (free) AND Expert reaction to problematic smart phone use in young people – Science Media Centre (free) AND Teens aren’t addicted to their phones – but we like to think they are – NewScientist (free)
Painless Visible Hematuria in Adults: An Algorithmic Approach Guiding Management
1 Dec, 2019 | 21:48h | UTCPainless Visible Haematuria in Adults: An Algorithmic Approach Guiding Management – Cureus (free)
Related Review: The Investigation of Hematuria – Deutsches Ärzteblatt international (free)
Bridging Anticoagulation Therapy: A Teachable Moment
29 Nov, 2019 | 07:37h | UTCBridging Anticoagulation Therapy: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
Related: 2017 ACC Expert Consensus Decision Pathway for Periprocedural Management of Anticoagulation in Patients With Nonvalvular Atrial Fibrillation (free) AND Bridging Anticoagulation: Primum Non Nocere – Journal of the American College of Cardiology (free) AND Periprocedural heparin bridging in patients receiving oral anticoagulation: a systematic review and meta-analysis – BMC Cardiovascular Disorders (free) AND Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation – New England Journal of Medicine (free)
Study: Proton Pump Inhibitors May be Associated with Increased the Risk of Viral Gastroenteritis
29 Nov, 2019 | 07:46h | UTCCommentaries: Further Evidence to Monitor Long-term Proton Pump Inhibitor Use – JAMA Network Open (free) AND Prescription antacids may increase risk for stomach infections – UPI (free)
[Abstract Only] Randomized Trial: Supplemental MRI Screening vs. Usual Care with Mammography Only for Women with Extremely Dense Breast Tissue
28 Nov, 2019 | 10:39h | UTCSupplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)
“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)
Related Commentary on Twitter
In this randomized trial, women with extremely dense breast tissue were invited to undergo MRI screening or received only mammography during a 2-year screening period. https://t.co/tZmcappO00
— NEJM (@NEJM) November 27, 2019
WHO Consolidated Guidelines on HIV Testing Services for a Changing Epidemic
28 Nov, 2019 | 10:33h | UTCConsolidated guidelines on HIV testing services for a changing epidemic – World Health Organization (free)
Commentaries: WHO Releases New HIV Testing Guidelines To Help Expand Treatment Coverage, Reduce HIV Transmission – Health Policy Watch (free) AND WHO releases new HIV testing guidelines – Global ID News (free)
FDA Issues Safety Warning on Cannabidiol Products
28 Nov, 2019 | 10:29h | UTCCommentaries: FDA’s Warning On CBD: Cannabis Stocks Drop, Companies Object – Forbes (free) AND ‘CBD has the potential to harm you,’ FDA warns consumers – MarketWatch (free)
Related: Cannabidiol Products Are Everywhere, but Should People Be Using Them? – JAMA (free for a limited period) AND NICE Guideline: Cannabis-Based Medicinal Products (free Guideline and other resources)
Perspective: What Are the Benefits of Probiotics?
28 Nov, 2019 | 10:28h | UTCWhat Are the Benefits of Probiotics? – The New York Times (free)
Related: Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries) AND The Problem With Probiotics – The New York Times (free)
Cohort Study: Associations of Dairy Intake with Risk of Mortality in Women and Men
28 Nov, 2019 | 10:24h | UTCRelated meta-analysis: Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose–response meta-analysis of prospective cohort studies – European Journal of Epidemiology (free)
Breast Cancer Screening and Diagnosis: A Synopsis of the European Breast Guidelines
27 Nov, 2019 | 08:19h | UTCCommentary: European guidelines for breast cancer screening differ from U.S. recommendations – ACP Internist (free)
Related: ACP Guideline: Screening for Breast Cancer in Average-Risk Women (other guidelines and commentaries on the subject)
Podcast: Update in Sleep Medicine
27 Nov, 2019 | 08:08h | UTC#184 Update in Sleep Medicine: LIVE from CHEST 2019! – The Curbsiders Internal Medicine Podcast (free)
Viewpoint: Implementation Strategies for Cardiovascular Polypills
27 Nov, 2019 | 08:09h | UTCImplementation Strategies for Cardiovascular Polypills – JAMA (free for a limited period)
See also: Cardiovascular Disease Prevention at a Crossroads: Precision Medicine or Polypill? – JAMA (free)
Author Interview: Implementation Strategies for Cardiovascular Polypills (free)
Related: The Polypill Revisited: Why We Still Need Population-Based Approaches in the Precision Medicine Era (free for a limited period) AND Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population (randomized trials, commentaries and guideline on the subject)
Observational Study: Proton-pump Inhibitor Use is Associated with a Broad Spectrum of Neurological Adverse Events Including Impaired Hearing, Vision, and Memory
27 Nov, 2019 | 08:06h | UTCCommentary: PPIs linked to adverse neurological effects – Univadis (free registration required)
CDC Guidance: Tafenoquine for Prevention and Antirelapse Therapy for Malaria
27 Nov, 2019 | 07:44h | UTCCommentary: CDC Offers Guidance on Tafenoquine for Malaria Chemoprophylaxis – NEJM Journal Watch (free)
CDC Updates Guidance on Pneumococcal Vaccination
27 Nov, 2019 | 07:42h | UTCCommentary: PCV13 No Longer Recommended for All Seniors – NEJM Journal Watch (free)
Iron Deficiency Anemia Revisited
26 Nov, 2019 | 07:35h | UTCIron deficiency anaemia revisited – Journal of Internal Medicine (free)
Related: How we diagnose and treat iron deficiency anemia – American Journal of Hematology (free)
Alex Nowbar’s weekly review—22 November 2019
24 Nov, 2019 | 20:58h | UTCAlex Nowbar’s weekly review, 22 November 2019 – The BMJ Opinion (free)
Systematic Review: Comparisons of Exacerbations and Mortality Among Regular Inhaled Therapies for Patients with Stable COPD
24 Nov, 2019 | 20:55h | UTCRelated Guidelines: 2020 Global Strategy for Prevention, Diagnosis and Management of COPD – GOLD Reports 2020 (free PDF) AND Chronic obstructive pulmonary disease in over 16s: diagnosis and management – National Institute for Health and Care Excellence (free)
Randomized Trial: Injectable 17-α-hydroxyprogesterone Not Effective for the Prevention of Recurrent Preterm Birth
24 Nov, 2019 | 20:59h | UTCCommentary: Advice to pull a drug used to prevent premature birth sparks controversy – News Medical (free) AND Unexpected Findings in Confirmatory Trial of Preterm Birth Drug – MedPage Today (free registration required)
Related Study: A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine (free)
[Abstract Only] Cohort Study: Long-term Risk of Epilepsy, Psychiatric Disorders, and Mortality Among Children with Recurrent Febrile Seizures
24 Nov, 2019 | 20:52h | UTCEvaluation of Long-term Risk of Epilepsy, Psychiatric Disorders, and Mortality Among Children With Recurrent Febrile Seizures: A National Cohort Study in Denmark – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Risk of Epilepsy with Febrile Seizure – Journal Feed (free) AND Repeated febrile convulsions linked to epilepsy and psychiatric disorders – Aarhus University (free) AND Kids’ Fever-Related Convulsions Tied to Greater Risk of Epilepsy, Schizophrenia – PsychCentral (free)
Review: Bladder Pain Syndrome in Women
24 Nov, 2019 | 20:34h | UTCBladder Pain Syndrome in Women – JAMA (free for a limited period)
WHO Study: 81% of Adolescents Not Active Enough
22 Nov, 2019 | 08:40h | UTCNews Release: New WHO-led study says majority of adolescents worldwide are not sufficiently physically active, putting their current and future health at risk – World Health Organization (free)
Commentaries: Challenges in global surveillance of physical activity – The Lancet Child & Adolescent Health (free) AND Most Adolescents Around The World Are Insufficiently Active, Risking Current And Future Health – Health Policy Watch (free) AND A Majority of The World’s Teens Aren’t Getting Enough Physical Activity – TIME (free) AND More than 80% of adolescents not active enough, warns WHO – The Guardian (free) AND Sedentary teens risk health, hearts and minds: WHO study – Reuters (free)
Related Commentary on Twitter
NEW: Majority of adolescents worldwide are not sufficiently physically active, putting their current and future health at risk: findings from first ever global trends for girls and boys aged 11-17 years across 146 countries @WHO https://t.co/hGg1LpJuVr pic.twitter.com/CPDhikMXhi
— The Lancet Child & Adolescent Health (@LancetChildAdol) November 21, 2019
Study: Exposure to Tomographic Scans and Cancer Risks
22 Nov, 2019 | 08:30h | UTCExposure to Tomographic Scans and Cancer Risks – JNCI Cancer Spectrum (free)
Commentary: Radiation from CT scans associated with increased risk for cancer – Oxford University Press (free)
Related: Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea – JAMA Network Open (free) AND Retrospective Cohort: Radiation Exposure From Pediatric CT Scans and Subsequent Cancer Risk (link to abstract and commentary)


