Family Medicine
Randomized Trial: Efficacy of Fecal Microbiota Transplantation for Patients with Irritable Bowel Syndrome
7 Jan, 2020 | 01:40h | UTCRelated Articles: Faecal microbiota transplantation versus placebo for moderate-to-severe irritable bowel syndrome: a double-blind, randomised, placebo-controlled, parallel-group, single-centre trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text) AND The effect of fecal microbiota transplantation on IBS related quality of life and fatigue in moderate to severe non-constipated irritable bowel: Secondary endpoints of a double blind, randomized, placebo-controlled trial – EbioMedicine (free)
Podcast: GERD and Dyspepsia
6 Jan, 2020 | 23:22h | UTC#188 GERD and Dyspepsia with Dr. Amy Oxentenko MD – The Curbsiders Internal Medicine Podcast (free audio and text)
See also: Episode List
Podcast: Common Cases of Medical Overuse
6 Jan, 2020 | 23:23h | UTC#189 Medical Overuse: Common Cases – The Curbsiders Internal Medicine Podcast (free audio and text)
See also: Episode List
[Abstract Only] Open-Label Randomized Trial: Oseltamivir vs. Usual Care for Influenza-like Illness in Primary Care
6 Jan, 2020 | 23:21h | UTCOseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries (with conflicting opinions): Tamiflu, Cure-All – Emergency Literature of Note (free) AND Flu antiviral has bigger benefits for sicker, older patients – University of Oxford (free)
Related Systematic Reviews: Neuraminidase inhibitors for preventing and treating influenza in adults and children – Cochrane Library (free) AND Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments – The BMJ (free) AND Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials – The Lancet (free registration required) AND Effectiveness of oseltamivir in adults: a meta-analysis of published and unpublished clinical trials – Family Practice (free)
Related Commentary on Twitter
New paper published in the Lancet found a moderate improvement in symptoms in pts treated with open label oseltamivir compared to usual care. Any one else find it curious it worked equally well in pts with and without confirmed influenza? https://t.co/KpBM1xMOTu pic.twitter.com/GcGi4yFBVO
— Rory Spiegel (@EMNerd_) January 3, 2020
Guideline: ADA 2020 Standards of Medical Care in Diabetes
25 Dec, 2019 | 21:43h | UTCJust published! New ADA 2021 Guideline for the Management of Diabetes
Guideline Homepage: ADA 2020 Standards of Medical Care in Diabetes – American Diabetes Association (free supplement)
Commentaries: ADA 2020 Standards of Care Incorporate CVD Risk Stratification, New Medications – Endocrinology Advisor (free) AND ADA releases 2020 standards of medical care in diabetes – University of North Carolina at Chapel Hill School of Medicine (free)
See also: Standards of Medical Care in Diabetes—2020 Abridged for Primary Care Providers – American Diabetes Association (free PDF) AND 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) – Diabetologia (free)
See ADA 2020 Guideline topics below:
Introduction: Standards of Medical Care in Diabetes—2020
Summary of Revisions: Standards of Medical Care in Diabetes—2020
- Improving Care and Promoting Health in Populations: Standards of Medical Care in Diabetes—2020
- Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2020
- Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2020
- Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Medical Care in Diabetes—2020
- Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2020
- Glycemic Targets: Standards of Medical Care in Diabetes—2020
- Diabetes Technology: Standards of Medical Care in Diabetes—2020
- Obesity Management for the Treatment of Type 2 Diabetes: Standards of Medical Care in Diabetes—2020
- Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes—2020
- Cardiovascular Disease and Risk Management: Standards of Medical Care in Diabetes—2020
- Microvascular Complications and Foot Care: Standards of Medical Care in Diabetes−2020
- Older Adults: Standards of Medical Care in Diabetes—2020
- Children and Adolescents: Standards of Medical Care in Diabetes−2020
- Management of Diabetes in Pregnancy: Standards of Medical Care in Diabetes—2020
- Diabetes Care in the Hospital: Standards of Medical Care in Diabetes—2020
Related Commentary on Twitter
ADA's "Standards of Medical Care in Diabetes—2020" is finally here! Featuring American Diabetes Association's latest clinical practice recommendations, the global standard for diabetes care. #ADASOC2020
READ NOW (OPEN ACCESS): https://t.co/CCArNKXi9D pic.twitter.com/Yj9gExpVdG
— ADA Professional Publications (@ADA_Pubs) December 20, 2019
[Abstract Only] Randomized Trial: Alcohol Abstinence Reduces Recurrence of Atrial Fibrillation
5 Jan, 2020 | 14:20h | UTCAlcohol Abstinence in Drinkers with Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Cutting out alcohol may reduce atrial fibrillation episodes – Reuters (free) AND Atrial Fibrillation and Alcohol Abstinence – MedicalResearch.com (free) AND Alcohol Abstinence Linked to Lower Risk for Atrial Fibrillation Recurrence – NEJM Journal Watch (free)
Related Commentary on Twitter
Excessive alcohol consumption associated with AFib. Patients with paroxysmal or persistent AFib who were in sinus rhythm and who were consuming 10 or more drinks per week were randomly assigned to either alcohol abstinence or continued drinking for 6 mos. https://t.co/LXU274pwsi
— NEJM (@NEJM) January 1, 2020
Another Observational Study Suggests One Dose of HPV Vaccine may be Enough
5 Jan, 2020 | 13:25h | UTCCommentaries: One dose of HPV vaccine may prevent infection from cancer-causing virus, study reveals – News Medical (free) AND Just 1 dose of the HPV vaccine may protect against infection, new study suggests – CNN (free)
Related: Systematic Review: Comparison of Different HPV Vaccine Types and Dose Schedules for Prevention of HPV‐related Disease in Females and Males – Cochrane Library (free) AND Large Observational Study Suggests One Dose of HPV Vaccine May Be as Effective as Three (free)
Review: Vaccination of Adults in General Medical Practice
5 Jan, 2020 | 13:15h | UTCVaccination of Adults in General Medical Practice – Mayo Clinic Proceedings (free)
Related Immunization Tables: WHO recommendations for routine immunization – summary tables – World Health Organization (free) AND Recommended Adult Immunization Schedule for ages 19 years or older, United States, 2019 – Centers for Disease Control and Prevention (CDC) (free)
Review: Routine Childhood Vaccines Given in the First 11 Months After Birth
5 Jan, 2020 | 13:16h | UTCRoutine Childhood Vaccines Given in the First 11 Months After Birth – Mayo Clinic Proceedings (free)
Related Immunization Tables: WHO recommendations for routine immunization – summary tables – World Health Organization (free) AND Recommended Child and Adolescent Immunization Schedule for ages 18 years or younger, United States, 2019 – Centers for Disease Control and Prevention (CDC) (free)
Management of Type 2 Diabetes in Developing Countries: Balancing Optimal Glycemic Control and Outcomes with Affordability and Accessibility to Treatment
5 Jan, 2020 | 13:12h | UTC
Meta-Analysis: Effectiveness of Management Strategies for Uninvestigated Dyspepsia
12 Dec, 2019 | 08:15h | UTCCommentary: Managing Dyspepsia with “Test and Treat” Ranked Best Strategy – NEJM Journal Watch (free)
Related Commentary on Twitter
#BMJResearch on the effectiveness of management strategies for uninvestigated dyspepsia found that testing for H pylori and eradication treatment in those who test positive ranked first but was not superior to other strategies @alex_ford12399 https://t.co/tmpbSCfjpc
— The BMJ (@bmj_latest) December 11, 2019
USPSTF Recommendation Statement: Screening for Abdominal Aortic Aneurysm
11 Dec, 2019 | 08:29h | UTCRecommendation Statement: Screening for Abdominal Aortic Aneurysm – US Preventive Services Task Force (free)
Evidence Report: Primary Care Screening for Abdominal Aortic Aneurysm – JAMA (free)
JAMA Editorials: Updated Guidelines on Screening for Abdominal Aortic Aneurysms (free) AND Updated US Preventive Services Task Force Recommendations for Abdominal Aortic Aneurysm—Are We Really Up To Date? (free) AND Screening for Abdominal Aortic Aneurysm—A Call to Arms? (free)
Author Interview: USPSTF Recommendation: Screening for Abdominal Aortic Aneurysm (free audio)
AAP Policy Statement: Unique Needs of the Adolescent
11 Dec, 2019 | 08:26h | UTCUnique Needs of the Adolescent – Pediatrics (free)
News Releases: American Academy of Pediatrics Describes the Unique Needs of Adolescents With New Policy Statement – American Academy of Pediatrics (free) AND AAP policy: What doctors need to consider when caring for 11- to 21-year-olds – AAP News (free)
Study: Even Light Alcohol Consumption Linked to Increased Cancer Risk
10 Dec, 2019 | 08:28h | UTCLight to moderate amount of lifetime alcohol consumption and risk of cancer in Japan – Cancer (free)
Commentaries: Even light alcohol consumption linked to higher cancer risk in Japan – Wiley (free)
Related: Alcohol and Cancer: A Statement of the American Society of Clinical Oncology (free Statement and commentaries) AND Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies – The Lancet (free study and commentaries)
Cognitive Symptoms of Alzheimer’s Disease: Clinical Management and Prevention
9 Dec, 2019 | 01:28h | UTCState of the Art Review: Cognitive symptoms of Alzheimer’s disease: clinical management and prevention – The BMJ (free for a limited period)
NICE Guideline: Menopause
6 Dec, 2019 | 10:50h | UTCMenopause: diagnosis and management – National Institute for Health and Care Excellence (free)
Ann Robinson’s research reviews—5 December 2019
6 Dec, 2019 | 08:38h | UTCAnn Robinson’s research reviews, 5 December 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals
Cohort Study: Maternal Diabetes During Pregnancy Linked to Early Onset of Cardiovascular Disease in Offspring
5 Dec, 2019 | 10:45h | UTCCommentaries: Link between diabetes in mothers and heart disease in children – OnMedica (free) AND Preventing and treating diabetes in women of childbearing age could reduce heart disease risk in the next generation – The BMJ Opinion (free)
[Abstract Only] Cohort Study: Hair Dye and Chemical Straightener Associated with Increased Risk of Breast Cancer
5 Dec, 2019 | 07:49h | UTCHair dye and chemical straightener use and breast cancer risk in a large US population of black and white women – International Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Permanent hair dye and straighteners may increase breast cancer risk – NIH News Releases (free) AND Hair Dyes And Straighteners Linked To Higher Cancer Risk, Especially For Black Women – NPR (free)
Study: Early Introduction of Allergenic Foods Can Prevent Food Allergies in High Risk Infants
5 Dec, 2019 | 10:28h | UTCSee also: Factors influencing adherence in a trial of early introduction of allergenic food – The Journal of Allergy and Clinical Immunology (free) AND Challenges experienced with early introduction and sustained consumption of allergenic foods in the Enquiring About Tolerance (EAT) study: A qualitative analysis – The Journal of Allergy and Clinical Immunology (free)
Original EAT Study: Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants – New England Journal of Medicine (free)
Commentaries: Introducing peanuts and eggs early can prevent food allergies in high risk infants – King’s College London (free) AND Expert reaction to three studies looking at early introduction of allergenic foods to infants – Science Media Centre (free)
Related Guidelines: AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease (free guidance and commentaries) AND Timing of introduction of allergenic solids for infants at high risk – Canadian Paediatric Society (free)
Systematic Review: Metformin for Prevention or Delay of Type 2 Diabetes Mellitus and Its Associated Complications
4 Dec, 2019 | 08:24h | UTCMetformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus – Cochrane Library (free)
Review: Celiac Disease
4 Dec, 2019 | 08:20h | UTCCeliac Disease – Mayo Clinic Proceedings (free)
Related Guidelines: European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders (free) AND ACG Clinical Guidelines: Diagnosis and Management of Celiac Disease (free) AND Coeliac Disease: Recognition, Assessment and Management – NICE Guideline (free) AND European Society for Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2019 – Journal of Pediatric Gastroenterology and Nutrition (free PDF)
AAP Policy Statement: Emergency Contraception
3 Dec, 2019 | 08:15h | UTCEmergency Contraception – Pediatrics (free)
Related: Committee Opinion No 707: Access to Emergency Contraception – American College of Obstetricians and Gynecologists (free) AND Interventions for emergency contraception – Cochrane Library (free)
Podcast: Managing Sarcopenia in Primary Care
3 Dec, 2019 | 01:32h | UTC#186 Sarcopenia: Raising the Bar in Primary Care – The Curbsiders Internal Medicine Podcast (free)
See also: Episode List
Perspective: The Case for Mandatory Vaccination
1 Dec, 2019 | 22:01h | UTCThe case for mandatory vaccination – Nature (free)
Related Opinion: Mandate Vaccination with Care (free commentaries)
“When immunization rates dip, legislation is often strengthened. But does the evidence stack up?”


