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Family Medicine

Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures

23 Oct, 2019 | 08:18h | UTC

Comparison of fracture risk using different supplemental doses of vitamin D, calcium or their combination: a network meta-analysis of randomised controlled trials – BMJ Open (free)

Commentary: Network meta-analysis nixes bone benefit from vitamin D, calcium – Univadis (free registration required)

Related Meta-Analysis: Calcium or Vitamin D Supplementation and Fracture Incidence in Older Adults – JAMA (free study and commentaries)

 


Meta-Analysis: Risk of Developing Parkinson Disease in Bipolar Disorder

23 Oct, 2019 | 08:03h | UTC

Risk of Developing Parkinson Disease in Bipolar Disorder: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)

Commentaries: Patients With Bipolar Disorder More Than 3 Times as Likely to Develop PD – AJMC (free) AND Looking for links between Parkinson’s and bipolar disorder – Medical News Today (free) AND Parkinson’s And Bipolar Disorder: Is There A Link Between The Two? – Medical Daily (free) AND Bipolar Disorder Raises Subsequent Risk of Parkinson’s – MedPage Today (free registration required)

 


Update on Management of Stable COPD

22 Oct, 2019 | 08:01h | UTC

Update on management of stable chronic obstructive pulmonary disease – Journal of Thoracic Disease (free)

Related Guidelines: 2019 Global Strategy for Prevention, Diagnosis and Management of COPD – GOLD Reports 2019 (free PDF) AND Chronic obstructive pulmonary disease in over 16s: diagnosis and management – National Institute for Health and Care Excellence (free)

 


NICE Guideline: Gastro-esophageal Reflux Disease and Dyspepsia in Adults

22 Oct, 2019 | 08:11h | UTC

Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management – National Institute for Health and Care Excellence (free)

 


Podcast: Tuberculosis Updates

22 Oct, 2019 | 08:05h | UTC

#178 Tuberculosis Updates with Laila Woc-Colburn MD – The Curbsiders Internal Medicine Podcast (free audio)

 


Systematic Review: Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD

20 Oct, 2019 | 23:11h | UTC

Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF)

Related: NICE Guideline: Acute Exacerbation of COPD (free)

 


Management of Irritable Bowel Syndrome with Diarrhea: A Review of Nonpharmacological and Pharmacological Interventions

22 Oct, 2019 | 07:23h | UTC

Management of irritable bowel syndrome with diarrhea: a review of nonpharmacological and pharmacological interventions – Therapeutic Advances in Gastroenterology (free)

Related Guidelines: Second Asian Consensus on Irritable Bowel Syndrome – Journal of Neurogastroenterology and Motility (free) AND Irritable bowel syndrome in adults: diagnosis and management – National Institute for Health and Care Excellence (NICE – UK) (free) AND AGA Guideline on the Laboratory Evaluation of Functional Diarrhea and Diarrhea-Predominant Irritable Bowel Syndrome in Adults (IBS-D) – Gastroenterology (free) AND Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 Revised Edition (free) AND Evidence-based clinical practice guidelines for irritable bowel syndrome – Journal of Gastroenterology (free) AND Canadian Association of Gastroenterology Clinical Practice Guideline for the Management of Irritable Bowel Syndrome (IBS) (free)

 


[Abstract Only] Randomized Trial: Metoprolol Not Effective for the Prevention of Acute Exacerbations of COPD

20 Oct, 2019 | 23:13h | UTC

Metoprolol for the Prevention of Acute Exacerbations of COPD – New England Journal of Medicine (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


Large Randomized Trial Findings Do Not Support Routine Ultrasonography in the Third Trimester for Low Risk Pregnancies

20 Oct, 2019 | 23:06h | UTC

Effectiveness of routine third trimester ultrasonography to reduce adverse perinatal outcomes in low risk pregnancy (the IRIS study): nationwide, pragmatic, multicentre, stepped wedge cluster randomised trial – The BMJ (free)

Commentary: Routine third trimester ultrasonography: Avoiding “too much too soon” – The BMJ Opinion (free)

 

Related Commentary on Twitter

 


US Physical Activity Guidelines: Current State, Impact and Future Directions

20 Oct, 2019 | 22:46h | UTC

US Physical Activity Guidelines: Current State, Impact and Future Directions – Trends in Cardiovascular Medicine (free)

Original Guideline: Physical Activity Guidelines for Americans (free resources)

See also: ACSM Scientific Pronouncements: Physical Activity Guidelines for Americans – American College of Sports Medicine (free articles)

 


Commentary on the New Pneumonia Guidelines Using GIFs & Some Mini-rants

20 Oct, 2019 | 23:03h | UTC

PulmCrit- Commentary on the new pneumonia guidelines using GIFs & some mini-rants (free)

Original Article: ATS/IDSA Guideline: Diagnosis and Treatment of Adults with Community-acquired Pneumonia (free resources)

 


Cohort Study: Weight Change Across Adulthood in Relation to all Cause and Cause Specific Mortality

20 Oct, 2019 | 22:40h | UTC

Weight change across adulthood in relation to all cause and cause specific mortality: prospective cohort study – The BMJ (free)

Commentaries: The timing of excess weight gain in our lifecycle matters – The BMJ Opinion (free) AND Weight gain in early adult life linked to increased risk of premature death – British Medical Journal (free) AND A new study says there could be a surprising consequence to losing weight later in life – CNN (free)

 


Meta-Analysis: Accelerometer- and Pedometer-Based Physical Activity Interventions Among Adults with Cardiometabolic Conditions

20 Oct, 2019 | 22:28h | UTC

Accelerometer- and Pedometer-Based Physical Activity Interventions Among Adults With Cardiometabolic Conditions: A Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentary: Walk and Talk: Step-Counting Devices Work Best When Paired With Doctor Consults – TCTMD (free)

 


Short Review: Using the 9-Item Patient Health Questionnaire to Screen for and Monitor Depression

20 Oct, 2019 | 22:24h | UTC

Using the 9-Item Patient Health Questionnaire to Screen for and Monitor Depression – JAMA (free for a limited period)

 


Short Review: Bisphosphonates for Postmenopausal Osteoporosis

20 Oct, 2019 | 22:23h | UTC

Bisphosphonates for Postmenopausal Osteoporosis – JAMA (free for a limited period)

 


Observational Study Suggests Angiotensin Receptor Blockers May Increase the Risk of Suicide

20 Oct, 2019 | 22:21h | UTC

Association Between Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, and Suicide – JAMA Network Open (free)

Commentaries: Concerns Raised by a Study of Suicide as an Adverse Drug Effect—Replicating Findings From Real-World Data – JAMA Network Open (free) AND Expert reaction to study looking at ACE inhibitor blood pressure drugs, angiotensin receptor blockers (ARBs) blood pressure drugs, and risk of suicide – Science Media Centre (free) AND Certain Blood Pressure Meds Tied to Suicide Risk in Study – HealthDay News (free)

 


Study: Cascades of Care After Incidental Findings

18 Oct, 2019 | 08:25h | UTC

Cascades of Care After Incidental Findings in a US National Survey of Physicians – JAMA Network Open (free)

Commentaries: The Important but Rarely Studied Cascade of Care – JAMA Network Open (free) AND Incidental Test Findings and the Burden They Create – MedPage Today (free registration required)

Related: Umbrella Review: Prevalence and Outcomes of Incidental Imaging Findings (free)

 

Related Commentary on Twitter

 


Urinary Tract Infections in Children: An Overview of Diagnosis and Management

18 Oct, 2019 | 08:19h | UTC

Urinary tract infections in children: an overview of diagnosis and management – BMJ Paediatrics Open (free)

 


Alex Nowbar’s weekly review—17 October 2019

18 Oct, 2019 | 08:08h | UTC

Alex Nowbar’s weekly review—17 October 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


NICE Guideline: End of Life Care for Adults

17 Oct, 2019 | 08:35h | UTC

End of life care for adults: service delivery – National Institute for Health and Care Excellence (free)

Related: Clinical Practice Guidelines for Quality Palliative Care, 4th Edition – National Consensus Project’s (free)

 


Exercise is Medicine in Oncology: Engaging Clinicians to Help Patients Move Through Cancer

17 Oct, 2019 | 08:37h | UTC

Exercise is medicine in oncology: Engaging clinicians to help patients move through cancer – CA: A Cancer Journal for Clinicians (free) AND

See also: Exercise Guidelines for Cancer Survivors: Consensus Statement from International Multidisciplinary Roundtable – Medicine & Science in Sports & Exercise (free) AND American College of Sports Medicine Roundtable Report on Physical Activity, Sedentary Behavior, and Cancer Prevention and Control – Medicine & Science in Sports & Exercise (free)

Commentaries: Exercise can now be prescribed like medicine for people with and beyond cancer – Penn State College of Medicine (free) AND Expert Panel: Cancer Treatment Plans Should Include Tailored Exercise Prescriptions – American College of Sports Medicine (ACSM) (free) AND Panel Finds Exercise May Lower Cancer Risk, Improve Outcomes – NIH Director’s Blog (free) AND Exercise Advice for Surviving Cancer, and Maybe Avoiding It – The New York Times (10 articles per month are free)

 


[Abstract Only] Study: 20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia

17 Oct, 2019 | 08:27h | UTC

20-Year Follow-up of Statins in Children with Familial Hypercholesterolemia – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: For Kids With Genetic Condition, Statins May Be Lifesavers – U.S. News (free) AND Starting Statin in Childhood Protects FH Hearts – MedPage Today (free registration required) AND Making the Case for Early Statins in Familial Hypercholesterolemia – Medscape (free registration required)

 


[Abstract Only] Randomized Trial: Medical vs. Surgical Treatment for Refractory Heartburn

17 Oct, 2019 | 08:28h | UTC

Randomized Trial of Medical versus Surgical Treatment for Refractory Heartburn – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Surgery for Refractory GERD Works for Small Subset of Patients – NEJM Journal Watch (free) AND Surgery Beats Meds for True Refractory Heartburn – MedPage Today (free registration required)

 


Analysis Suggests Statins for Primary Prevention has Marginal Benefits for Most People

17 Oct, 2019 | 08:26h | UTC

Statins for primary prevention of cardiovascular disease – The BMJ (free)

Commentaries: For most healthy people, benefits of statins ‘may be marginal at best’ – The BMJ (free) AND Expert reaction to benefits of statins for low risk patients – Science Media Centre (free) AND Statin Guidelines Continue to Perplex – NEJM Journal Watch (free)

 


Sodium-glucose Cotransporter Inhibitors in Type 2 Diabetes: Thinking Beyond Glucose Lowering

17 Oct, 2019 | 08:23h | UTC

Sodium-glucose cotransporter inhibitors in type 2 diabetes: thinking beyond glucose lowering – Canadian Medical Association Journal (free)

 


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