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Family Medicine

COVID-19: Undocumented Infections are the Infection Source for 79% of Documented Cases

17 Mar, 2020 | 08:51h | UTC

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) – Science (free)

Commentaries: 80% of COVID-19 spreads from people who don’t know they are sick – UPI (free) AND Coronavirus Is Hiding in Plain Sight – The New York Times (10 articles per month are free)

Related: COVID-19: Who Is Infectious? – Forbes (free) AND Infected people without symptoms might be driving the spread of coronavirus more than we realized – CNN (free)

 


Clinical Update: Tinnitus

17 Mar, 2020 | 08:38h | UTC

Tinnitus – JAMA (free for a limited period)

Related Guideline: Tinnitus: assessment and management – National Institute for Health and Care Excellence (free)

 


Observational Study Suggests Antibiotic Use Does Not Improve Outcomes in Children in the Emergency Department with Suspected Pneumonia

17 Mar, 2020 | 08:43h | UTC

Antibiotic Use and Outcomes in Children in the Emergency Department with Suspected Pneumonia – Pediatrics (free)

Commentary: Study questions role of antibiotics in kids’ pneumonia – CIDRAP (free)

 


Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

17 Mar, 2020 | 08:37h | UTC

Development and Validation of a Penicillin Allergy Clinical Decision Rule – JAMA Internal Medicine (free for a limited period)

 


Study: Characteristics of Pediatric SARS-CoV-2 Infection and Potential Evidence for Persistent Fecal Viral Shedding

16 Mar, 2020 | 07:50h | UTC

Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding – Nature Medicine (free)

Commentaries: How Does The Coronavirus Affect Kids? What We Know So Far About COVID-19 In Children – Forbes (free) AND Coronavirus study finds children with COVID-19 show milder symptom pattern – Reuters (free)

“Children infected with the #COVID19 outbreak coronavirus, SARS-CoV-2, show mild symptoms but prolonged shedding of viral RNA in feces, suggesting that the fecal–oral route might play a role in virus transmission #CORONAVIRUS” (via @NatureMedicine see Tweet)

 


WHO Guidance: Mental Health and Psychosocial Considerations During COVID-19 Outbreak

16 Mar, 2020 | 07:57h | UTC

Mental Health and Psychosocial Considerations During COVID-19 Outbreak – World Health Organization (free PDF)

Related: The psychological impact of quarantine and how to reduce it: rapid review of the evidence – The Lancet (free) AND Behavioural scientists form new front in battle against coronavirus – The Guardian (free)

“Minimize watching, reading or listening to news that causes you to feel anxious or distressed; seek information only from trusted sources and mainly to take practical steps to prepare your plans and protect yourself and loved ones.”

 


Review: Coronavirus Infections in Children Including COVID-19

16 Mar, 2020 | 07:52h | UTC

Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children – The Pediatric Infectious Diseases Journal (free PDF)

Commentary: COVID-19 appears less severe in children – Wolters Kluwer Health (free)

Related: A Review of Coronavirus Disease-2019 (COVID-19) – Indian Journal of Pediatrics (free) AND Detection of Covid-19 in Children in Early January 2020 in Wuhan, China – New England Journal of Medicine (free) AND Coronavirus with a baby: what you need to know to prepare and respond – The Conversation (free)

 


When Guidelines Recommend Shared Decision-making

16 Mar, 2020 | 07:45h | UTC

When Guidelines Recommend Shared Decision-making – JAMA (free)

Author Interview: When Guidelines Recommend Shared Decision-making (free audio)

 


Guideline: The Palliative Care of Patients with Incurable Cancer

16 Mar, 2020 | 07:42h | UTC

The Palliative Care of Patients with Incurable Cancer – Deutsches Ärzteblatt international (free)

 


Systematic Review: Causes of the Transmission and Control Measures of Outbreaks in Long-term Care Facilities

13 Mar, 2020 | 07:55h | UTC

A systematic review on the causes of the transmission and control measures of outbreaks in long-term care facilities: Back to basics of infection control – PLOS One (free)

 


Meta-Analysis of Randomized Trials: Little Benefit from Omega-3 Intake to Reduce Cardiovascular Disease Risk

13 Mar, 2020 | 07:52h | UTC

Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (free)

Summary: Omega-3 intake for cardiovascular disease – Cochrane Library (free)

Author Interview: Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease – Cochrane Library (free)

Commentary: Omega-3s Show No Overall Benefits for Heart Health or Cancer Prevention – The New York Times (free)

 


[Abstract Only] Meta-analysis of Randomized trials: Omega-3 Fats do not Protect Against Cancer

13 Mar, 2020 | 07:51h | UTC

Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials – British Journal of Cancer (link to abstract – $ for full-text)

Commentary: Omega-3 fats do not protect against cancer – University of East Anglia (free)

 


Systematic Review: Alcoholics Anonymous Very Effective for Alcohol Use Disorder

12 Mar, 2020 | 08:10h | UTC

Alcoholics Anonymous and other 12‐step programs for alcohol use disorder – Cochrane Library (free)

Author Interview: Alcoholics Anonymous and other 12-step programs for alcohol use disorder (free)

News Release: New Cochrane Review finds Alcoholics Anonymous and 12-Step Facilitation programs help people to recover from alcohol problems (free)

Commentaries: A new, big review of the evidence found that Alcoholics Anonymous works — for some – Vox (free) AND Alcoholics Anonymous validated by meta-analysis: ‘It absolutely does work’ – Stanford Medicine (free)

 


WHO Guideline: Key Messages and Actions for COVID-19 Prevention and Control in Schools

11 Mar, 2020 | 08:26h | UTC

Key messages and actions for COVID-19 prevention and control in schools – World Health Organization (free PDF)

News Release: COVID-19: IFRC, UNICEF and WHO issue guidance to protect children and support safe school operations – World Health Organization (free)

See also: Latest articles, guidelines and updates on the COVID-19 Outbreak (several free resources – updated daily)

 


Meta-Analysis: Dietary Fiber and Whole Grains in Diabetes Management

11 Mar, 2020 | 08:22h | UTC

Dietary fibre and whole grains in diabetes management: Systematic review and meta-analyses – PLOS Medicine (free)

 


NICE Guideline: Tinnitus Assessment and Management

11 Mar, 2020 | 08:24h | UTC

Tinnitus: assessment and management – National Institute for Health and Care Excellence (free)

 


Guideline: Coronavirus (COVID-19) Infection and Pregnancy

10 Mar, 2020 | 08:40h | UTC

Coronavirus (COVID-19) infection and pregnancy – Royal College of Obstetricians & Gynaecologists (free)

Related: Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow? – Acta Obstetricia et Gynecologica Scandinavica (free) AND Novel coronavirus infection and pregnancy – Ultrasound in Obstetrics and Gynecology (free) AND Preprint: CORONAVIRUS IN PREGNANCY AND DELIVERY: RAPID REVIEW AND EXPERT CONSENSUS – medRxiv (free PDF) AND Guidelines for pregnant women with suspected SARS-CoV-2 infection – The Lancet Infectious Diseases (free) AND Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know – American Journal of Obstetrics and Gynecology (free PDF) AND In the race for coronavirus vaccines, don’t leave pregnant women behind – STAT (free)

See also: Latest developments on the COVID-19/ SARS-CoV-2 Outbreak (several resources – updated daily)

 


Podcast: Polycystic Ovary Syndrome

10 Mar, 2020 | 08:35h | UTC

#198 PCOS: Polycystic Ovary Syndrome with Katherine Sherif MD – The Curbsiders Internal Medicine Podcast (free)

See also: Episode List

 


Doctors Working While Sick is Bad Enough in Ordinary Times. During the Covid-19 Outbreak it Could be Catastrophic

10 Mar, 2020 | 08:37h | UTC

Doctors working while sick is bad enough in ordinary times. During the Covid-19 outbreak it could be catastrophic – STAT (free)

Related Systematic Review: Working While Sick: A Systematic Review of Infectious Illness Presenteeism (free)

Related Study: Which healthcare workers work with acute respiratory illness? Evidence from Canadian acute-care hospitals during 4 influenza seasons: 2010–2011 to 2013–2014 – Infection Control & Hospital Epidemiology (free) AND Commentary: Sick hospital workers often expose patients to contagious illness – Reuters (free)

 


Observational Study Suggests Continuing ACE-I/ARBs in Patients with Declining kidney Function May Reduce Cardiovascular Risk Without Increased Risk of Progression to End-stage Kidney Disease

10 Mar, 2020 | 08:28h | UTC

Association Between Renin-Angiotensin System Blockade Discontinuation and All-Cause Mortality Among Persons With Low Estimated Glomerular Filtration Rate – JAMA Internal Medicine (free for a limited period)

Editorial: Continuation of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers in the Face of Kidney Disease Progression—Safe and Possibly Life Saving (free for a limited period)

 

Related Commentary on Twitter

 


Clinical Update: Diagnosis and Treatment of Clostridioides (Clostridium) difficile Infection in Adults in 2020

10 Mar, 2020 | 08:32h | UTC

Diagnosis and Treatment of Clostridioides (Clostridium) Difficile Infection in Adults in 2020 – JAMA (free for a limited period)

Related: Clostridioides Difficile: Diagnosis and Treatments (free BMJ review and guidelines on the subject) AND Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement – Intensive Care Medicine (free)

 


Review: Medical Reversals in Family Practice

8 Mar, 2020 | 20:40h | UTC

Medical Reversals in Family Practice: A Review – Current Therapeutic Research (free PDF)

Related: Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals (free)

 


Choosing Wisely in Rhinology: Five Things Physicians and Patients Should Question

8 Mar, 2020 | 20:38h | UTC

Choosing Wisely Canada rhinology recommendations – Journal of Otolaryngology – Head & Neck Surgery (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


[Abstract Only] Cohort Study: Sleep Irregularity Linked to Increased Risk of Cardiovascular Events

8 Mar, 2020 | 20:33h | UTC

Sleep Irregularity and Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Sleep Irregularity and Risk of Cardiovascular Events – American College of Cardiology (free) AND Better Sleep Linked With Reduced Risk of CVD, Improved Weight Loss – AJMC (free) AND Poor Sleepers at Higher Risk of CVD, MESA Data Suggest – TCTMD (free) AND Irregular sleep may increase risk of cardiovascular events – Brigham and Women’s Hospital (free) AND Irregular sleep may increase risk of cardiovascular problems – Medical News Today (free)

 


[Abstract Only] Cohort Study: Substituting Margarine, Butter, Mayonnaise, and Dairy Fat with Olive Oil Could Lead to Lower Risk of Cardiovascular Disease

8 Mar, 2020 | 20:31h | UTC

Olive Oil Consumption and Cardiovascular Risk in U.S. Adults – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Olive Oil Consumption and Cardiovascular Risk – American College of Cardiology (free) AND Higher Olive Oil Consumption Tied to Lower CVD Risk in U.S. Adults – NEJM Journal Watch (free) AND Use Olive Oil Instead of Saturated Fats for Heart Health, Study Suggests – CardioSmart (free)

 


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