Family Medicine
FDA Recommendations for Conserving Medical Supplies
24 Mar, 2020 | 11:23h | UTC- Ventilator Supply Mitigation Strategies: Letter to Health Care Providers – U.S. Food & Drug Administration
- Medical Glove Conservation Strategies: Letter to Health Care Providers – U.S. Food & Drug Administration
- Surgical Mask and Gown Conservation Strategies – Letter to Healthcare Providers – U.S. Food & Drug Administration
See also: Strategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention (free)
CDC Guidance: Preparing Long-term Care Facilities and Nursing Homes for COVID-19
24 Mar, 2020 | 11:28h | UTCRelated Guideline: Infection Prevention and Control guidance for Long-Term Care Facilities in the context of COVID-19 – World Health Organization (PDF)
Related Article: COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020 – CDC Morbidity and Mortality Weekly Report
Related Perspective: The Coronavirus’s Rampage Through a Suburban Nursing – The New York Times
CEBM Estimates Infection Rate Fatality (IFR) of COVID-19 at 0,20%
23 Mar, 2020 | 01:16h | UTCGlobal Covid-19 Case Fatality Rates – Centre for Evidence-Based Medicine, University of Oxford (free)
[Preprint] Randomized Trial: Favipiravir vs. Arbidol for COVID-19
23 Mar, 2020 | 01:18h | UTCFavipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial – medRxiv
Infection Prevention and Control guidance for Long-Term Care Facilities in the context of COVID-19
23 Mar, 2020 | 01:34h | UTCRelated Study: COVID-19 in a Long-Term Care Facility — King County, Washington, February 27–March 9, 2020 – CDC Morbidity and Mortality Weekly Report (free)
“Introduction of COVID-19 into a long-term residential care facility in Washington resulted in cases among 81 residents, 34 staff members, and 14 visitors; 23 persons died” (from CDC)
Loss of Smell and Taste Could be a Sign of COVID-19
23 Mar, 2020 | 01:11h | UTCPosition Statement: Loss of sense of smell as marker of COVID-19 infection – ENT-UK
See also: There’s An Unexpected Loss Of Smell And Taste In Coronavirus Patients – Forbes AND If you’ve lost your sense of smell or taste, you could be a ‘hidden carrier’ of the coronavirus – Business Insider
IDSA Statement: COVID-19 Prioritization of Diagnostic Testing
20 Mar, 2020 | 11:01h | UTCCOVID-19 Prioritization of Diagnostic Testing – Infectious Diseases Society of America (free PDF)
Summary: IDSA Statement On COVID-19 Testing Recommendations – Infectious Diseases Society of America (free)
Editorial by John P.A. Ioannidis: COVID-19: The Harms of Exaggerated Information and Non‐evidence‐based Measures
23 Mar, 2020 | 01:08h | UTCRelated Opinion Piece: A fiasco in the making? As the coronavirus pandemic takes hold, we are making decisions without reliable data – STAT (free)
Rebuttal 1: We know enough now to act decisively against Covid-19. Social distancing is a good place to start – STAT (free)
Rebuttal 2: A Rebuttal to “A Fiasco in the Making?” – Hilda Bastian (Free)
New Preliminary Studies with Hydroxychloroquine:
20 Mar, 2020 | 10:57h | UTCThis was an open-label study with only 42 patients without patient-relevant endpoints. The 6 patients that received Hydroxychloroquine + Azithromycin achieved more efficient virus elimination than control patients.
New in Vitro Study: Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro – Cell Discovery (free)
Related Articles: In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) – Clinical Infectious Diseases (free PDF) AND New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? – International Journal of Antimicrobial Agents (free) AND A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 – Journal of Critical Care (free) AND Of chloroquine and COVID-19 – Antiviral Research (free)
CDC Guideline: Strategies for Optimizing the Supply of Facemasks
20 Mar, 2020 | 11:03h | UTCStrategies for Optimizing the Supply of Facemasks – Centers for Disease Control and Prevention (free)
Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the Coronavirus Disease 2019 (COVID-19) Pandemic
20 Mar, 2020 | 11:05h | UTCCommentary: CVD in the Setting of COVID-19: Considerations to Prepare Patients, Providers, Health Systems – American College of Cardiology (free)
Management of Kidney Stones in 2020
20 Mar, 2020 | 10:54h | UTCManagement of Kidney Stones in 2020 – JAMA (free for a limited period)
Related Guidelines: Renal and ureteric stones: assessment and management – National Institute for Health and Care Excellence (free) AND Dietary and Pharmacologic Management to Prevent Recurrent Nephrolithiasis in Adults: A Clinical Practice Guideline From the American College of Physicians (free) AND Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement – Journal of Nephrology (free) AND Medical Management of Kidney Stones: AUA Guideline (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I (free) AND Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART II (free) AND The Urological Association of Asia clinical guideline for urinary stone disease – International Journal of Urology (free)
FDA: Stop SGLT2 Inhibitors Before Scheduled Surgery
20 Mar, 2020 | 10:52h | UTCCommentary: FDA advises stopping SGLT2 inhibitor treatment prior to surgery – The Hospitalist (free)
“- Canagliflozin, dapagliflozin, and empagliflozin should each be discontinued at least three days before scheduled surgery.
– Ertugliflozin should be discontinued at least four days before scheduled surgery.
– Blood glucose levels should be carefully monitored after discontinuation of the SGLT2 inhibitor and appropriately managed before surgery.”
Video: Coronavirus Update with Anthony Fauci, MD
19 Mar, 2020 | 11:04h | UTCCoronavirus Update with Anthony Fauci, MD – March 18, 2020 – JAMA (free)
Study: SARS-CoV-2 Infection in Children
19 Mar, 2020 | 10:59h | UTCSARS-CoV-2 Infection in Children – New England Journal of Medicine (free)
Related Articles: Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China – Peditrics (free) Detection of Covid-19 in Children in Early January 2020 in Wuhan, China – New England Journal of Medicine (free) AND Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children – The Pediatric Infectious Diseases Journal (free PDF) AND Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding – Nature Medicine (free)
[Abstract Only] Randomized Trial: Surgery vs. Conservative Care for Persistent Sciatica Lasting 4 to 12 Months
19 Mar, 2020 | 11:03h | UTCSurgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: What Works Best to Ease the Pain of Sciatica? – HealthDay News (free)
Randomized Trial: No Benefit from Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
19 Mar, 2020 | 11:01h | UTCEditorial: Covid-19 — The Search for Effective Therapy (free)
See also: Interview with Dr. Eric Rubin and Dr. Lindsey Baden on new research on possible treatments for Covid-19 – New England Journal of Medicine (free)
Study: Diarrhea is a Prominent Symptom of COVID-19
19 Mar, 2020 | 10:56h | UTCCommentaries: Study from The American Journal of Gastroenterology Reveals Diarrhea is a Prominent Symptom of COVID-19 – American College of Gastroenterology (free) AND Diarrhea a key symptom in 1 of 4 COVID-19 patients, study finds – UPI (free)
Podcast: New Research on Possible Treatments for Covid-19
19 Mar, 2020 | 10:57h | UTC
Perspective: Confirmatory Trial for Drug to Prevent Preterm Birth Finds No Benefit, So Why Is It Still Prescribed?
19 Mar, 2020 | 10:52h | UTCConfirmatory Trial for Drug to Prevent Preterm Birth Finds No Benefit, So Why Is It Still Prescribed? – JAMA (free for a limited period)
Original Article: Randomized Trial: Injectable 17-α-hydroxyprogesterone Not Effective for the Prevention of Recurrent Preterm Birth (free study and commentaries)
Related Study: A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine (free)
Coronaviruses and the Cardiovascular System: Acute and Long-term Implications
19 Mar, 2020 | 10:43h | UTC
Meta-Analysis: Psychotherapy for Depression Across Different Age Groups
19 Mar, 2020 | 10:41h | UTCEditorial: The Age of Depression and Its Treatments (free)
Commentary: Psychotherapy not as effective for kids, adolescents with depression, study says – UPI (free)
[Abstract Only] Study: Consequences of Measles Undervaccination
18 Mar, 2020 | 09:49h | UTCConsequences of Undervaccination – Measles Outbreak, New York City, 2018-2019 – New England Journal of Medicine (link to abstract – $ for full-text)
Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China
17 Mar, 2020 | 08:45h | UTCCommentary: Children with COVID-19 Impacted Less Severely Than Adults: Study – American Academy of Pediatrics (free)
Podcast: Hyperkalemia, Diet, K+ Binders, Exercise
17 Mar, 2020 | 08:40h | UTCSee also: Episode List