Family Medicine
Review: Polypharmacy management in older patients
19 Jan, 2021 | 01:26h | UTCPolypharmacy Management in Older Patients – Mayo Clinic Proceedings
Systematic review: Little evidence of benefit from vitamin D supplementation on linear growth and other health outcomes among children under five years of age
19 Jan, 2021 | 01:11h | UTC
Returning to physical activity after Covid-19
17 Jan, 2021 | 22:19h | UTCReturning to physical activity after covid-19 – The BMJ
Commentary: Returning to physical activity after a Covid-19 infection – Medical Centre
Commentaries on Twitter
"Returning to #PhysicalActivity after #COVIDー19 should be gradual, individualised, and based on subjective tolerance of the activity.".#exercise #rehab
⛹️♀️🏃⚽🎾🏌️🏋️♂️🏊♀️🚴♂️🤸♀️🏸🤼
HT- @bmj_latesthttps://t.co/GnqwCBkZRN pic.twitter.com/k4nsDI6ApU
— Christopher Tuckett MCSP (@HealthPhysio) January 15, 2021
Professional experience suggests that after mild suspected covid-19 a proportion of people experience a prolonged recovery. What are the risks of physical activity after covid-19 and how to know if a patient can safely return to physical exercise?https://t.co/19Cfi4p5Ck
— The BMJ (@bmj_latest) January 11, 2021
Herd immunity by infection is not an option
17 Jan, 2021 | 22:16h | UTCHerd immunity by infection is not an option – Science
CDC Study: Performance of an antigen-based test for asymptomatic and symptomatic SARS-CoV-2
17 Jan, 2021 | 22:10h | UTC
Commentary on Twitter
New @CDCMMWR shows COVID-19 antigen tests can be fast and inexpensive but sometimes require a second test to confirm the result. Protect others until your test result is confirmed. Learn more: https://t.co/xu4buZMM0K. pic.twitter.com/GbRfrFscKI
— CDC (@CDCgov) December 31, 2020
Meta-analysis: Prophylactic macrolides beneficial for patients with COPD with frequent exacerbations
17 Jan, 2021 | 22:09h | UTCSummary: Prophylactic antibiotics for people with COPD – Cochrane Library
Meta-analysis of observational studies: Proton pump inhibitors linked to increased risk for recurrent Clostridioides difficile infection
17 Jan, 2021 | 22:00h | UTC
Consensus statement: Diagnosis, treatment, and follow-up of heart failure patients by general practitioners
17 Jan, 2021 | 21:48h | UTC
Review: Gastroesophageal reflux disease
17 Jan, 2021 | 21:52h | UTCGastroesophageal Reflux Disease: A Review – JAMA (free for a limited period)
[Preprint] Past COVID-19 infection provides some immunity but people may still carry and transmit virus
15 Jan, 2021 | 09:02h | UTCSee also: Covid-19: Past infection provides 83% protection for five months but may not stop transmission, study finds – The BMJ AND COVID reinfections are unusual — but could still help the virus to spread – Nature AND COVID-19 infection gives some immunity, but virus can still be spread, study finds – Reuters AND Expert reaction to a preprint from the SIREN study looking at SARS-CoV-2 infection rates in antibody positive healthcare workers – Science Media Centre
Perspective: Ivermectin for COVID-19 — Breakthrough Treatment or Hydroxychloroquine Redux?
15 Jan, 2021 | 08:51h | UTCRelated video: Ivermectin For COVID-19 | A Doctor Explains – ZDoggMD
NIH Guideline Statement: “there are insufficient data to recommend either for or against the use of ivermectin for the treatment of COVID-19”
15 Jan, 2021 | 08:53h | UTC
Progression of myopia in school-aged children after COVID-19 home confinement
15 Jan, 2021 | 08:55h | UTCProgression of Myopia in School-Aged Children After COVID-19 Home Confinement – JAMA Ophthalmology
Commentaries: 2020 as the Year of Quarantine Myopia – JAMA Ophthalmology AND How Does Home Confinement Impact Children’s Eyesight? – AJMC AND COVID-19: Home Quarantine Linked to Increase in Myopia Among Younger Children – NEJM Journal Watch AND Vision problems arise in young school kids in COVID-19 quarantine – CIDRAP
Interview: 2020 as the Year of Quarantine Myopia
Meta-analysis of randomized trials: patients adhering to a low carbohydrate diet for six months may experience remission of diabetes without adverse consequences
15 Jan, 2021 | 08:43h | UTCCommentary: Short term low carbohydrate diet linked to remission of type 2 diabetes – The BMJ
Short term low carbohydrate diet linked to remission of type 2 diabetes in new #BMJResearch. But further trials are needed to determine longer term effects, say researchers @methodsnerd et al.
Includes a #VisualAbstract by @will_s_t #BMJInfographichttps://t.co/qihKAib11U pic.twitter.com/3rPH0ZrSGL— The BMJ (@bmj_latest) January 14, 2021
Meta-analysis of randomized trials: SGLT-2 inhibitors and GLP-1 receptor agonists reduce cardiovascular and renal outcomes in type 2 diabetes
15 Jan, 2021 | 08:41h | UTCCalculator based on the results: interactive decision support tool for outcomes
Cohort study: Even small amounts of alcohol consumption linked to increased risk of atrial fibrillation
15 Jan, 2021 | 08:40h | UTCEditorial: Alcohol consumption, atrial fibrillation, and cardiovascular disease: finding the right balance
Clinical trial finds vitamin D does not ward off colds and flu
15 Jan, 2021 | 08:33h | UTC
Meta-analysis: Saliva vs. nasopharyngeal swabs equally sensitive for Covid-19 diagnosis
14 Jan, 2021 | 02:13h | UTCCommentary: Saliva, Nasopharyngeal Samples Equally Sensitive for SARS-CoV-2 – Physician’s Weekly
Commentary on Twitter
https://twitter.com/EricTopol/status/1348758183846703104
Study estimates 50% of new SARS-CoV-2 infections have originated from exposure to asymptomatic or pre-symptomatic individuals
14 Jan, 2021 | 02:08h | UTCSARS-CoV-2 Transmission From People Without COVID-19 Symptoms – JAMA Network Open
Commentary: At least 50% of COVID-19 cases spread from people without symptoms, a new study found – Business Insider AND More than half of Covid-19 infections acquired from asymptomatic carriers – MedicalResearch
Commentary on Twitter
https://twitter.com/TennantRuth/status/1348208811039985665
Study: Despite recommendations, less than 2 percent of patients with treatment-resistant hypertension were tested for primary aldosteronism in a large U.S. cohort
14 Jan, 2021 | 01:55h | UTCTesting for Primary Aldosteronism and Mineralocorticoid Receptor Antagonist Use Among U.S. Veterans: A Retrospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Primary Aldosteronism Testing Rare in Treatment-Resistant HTN – HealthDay AND Primary Aldosteronism Testing Rare for Patients with Resistant Hypertension – NEJM Journal Watch
Commentary from the author on Twitter (thread – click for more)
Our new study is out in @AnnalsofIM w/@BhallaResearch @thebyrdlab @johnleppert! 👇https://t.co/UCrAD4ed0w
We asked: Are patients w/treatment resistant HTN being appropriately tested for primary aldosteronism (PA) & managed w/mineralocorticoid receptor antagonists (MRAs)? 1/ pic.twitter.com/jO4cqA37sD
— Jordy Cohen, MD, MSCE (@jordy_bc) December 28, 2020
Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin
14 Jan, 2021 | 01:57h | UTCEditorial: Evolving Issues in the Use of Antibiotics for the Treatment of Uncomplicated Appendicitis
Commentary: More Support for Single-Drug Antibiotics for Uncomplicated Appendicitis – Physician’s Weekly
Commentary on Twitter
In this RCT comparing 7d oral moxifloxacin vs 2d IV ertapenam 5d oral levofloxacin metronidazole for adults w uncomplicated #appendicitis, Tx success was >65% for both, but oral #antibiotics did not meet noninferiority criteria vs IV PO https://t.co/SwcopsGZTm #VisualAbstract
— JAMA (@JAMA_current) January 12, 2021
Systematic review: Does behavioral support help people to stop smoking?
14 Jan, 2021 | 01:46h | UTCSummary: Does behavioural support help people to stop smoking? – Cochrane Library
Short review: How Dangerous are new COVID-19 strains?
13 Jan, 2021 | 02:31h | UTCHow Dangerous Are New COVID-19 Strains? – Council on Foreign Relations
Commentary on Twitter
How dangerous are the B.1.1.7 and 501Y.V2 hyper-transmissible strains?
by @AdamJKucharski @CFR_orghttps://t.co/aycWMN3b5h
h/t @Karl_Lauterbach pic.twitter.com/JlaFzzP06t— Eric Topol (@EricTopol) January 11, 2021
Masks and face coverings for the lay public: A narrative update
13 Jan, 2021 | 02:23h | UTCMasks and Face Coverings for the Lay Public: A Narrative Update – Annals of Internal Medicine
Commentary on Twitter (thread – click for more)
Masks work.
A new and comprehensive update from @trishgreenhalgh
et al."Evidence that the virus can be airborne (and therefore be inhaled) and that masking policies, when effectively delivered, save lives is now strong."https://t.co/Tl9VrmPNlW pic.twitter.com/zfuV774jyN
— Laura McCall #NoMassInfection (@equibotanica) December 29, 2020
Video (3 min): Which Covid vaccine is better? Pfizer v Oxford v Moderna
13 Jan, 2021 | 02:21h | UTCWhich Covid vaccine is better? Pfizer v Oxford v Moderna – BBC