Family Medicine
An evidence review of face masks against COVID-19
13 Jan, 2021 | 02:26h | UTCAn evidence review of face masks against COVID-19 – Proceedings of the National Academy of Sciences
Commentary on Twitter
https://mobile.twitter.com/jeremyphoward/status/1348771993949151232
Loss of smell in mild Covid-19 cases occurs 86% of the time, study says
13 Jan, 2021 | 02:20h | UTCLoss of smell in mild Covid-19 cases occurs 86% of the time, study says – CNN
Original study: Prevalence and 6‐month recovery of olfactory dysfunction: a multicentre study of 1363 COVID‐19 patients – Journal of Internal Medicine
Randomized trial: Stable supportive shoes improve knee osteoarthritis symptoms when compared to flat flexible shoes
13 Jan, 2021 | 02:08h | UTCThe Effect of Flat Flexible Versus Stable Supportive Shoes on Knee Osteoarthritis Symptoms: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Summary for Patients: The Effect of Flat Flexible Versus Stable Supportive Shoes on Knee Osteoarthritis Symptoms
Commentary: Stable, Supportive Shoes Better for Knee Osteoarthritis Pain – NEJM Journal Watch
Systematic review: Acute treatments for episodic migraine
13 Jan, 2021 | 01:56h | UTCAcute Treatments for Episodic Migraine – Agency for Healthcare Research and Quality
Full text: Acute Treatments for Episodic Migraine
Evidence summary: Acute Treatments for Episodic Migraine
Systematic review: Treatments for acute pain
13 Jan, 2021 | 01:55h | UTCTreatments for Acute Pain: A Systematic Review – Agency for Healthcare Research and Quality
Full text: Treatments for Acute Pain
Evidence summary: Treatments for Acute Pain
AASM Guideline: Behavioral and psychological treatments for chronic insomnia disorder in adults
13 Jan, 2021 | 01:58h | UTCCommentary: New guideline encourages use of cognitive behavioral therapy for insomnia in adults – ACP Internist
USPSTF recommends screening for Hepatitis B Virus infection in adolescents and adults
13 Jan, 2021 | 01:43h | UTCAuthor Interview: USPSTF Recommendation: Screening for Hepatitis B Virus Infection in Adolescents and Adults
Patient Page: Screening for Hepatitis B in Nonpregnant Adolescents and Adults – JAMA
CDC Study: Reducing quarantine to fewer than 14 days might be easier to comply with but carries some risk of spreading the virus
12 Jan, 2021 | 02:03h | UTCCommentaries: Shorter Quarantines Can Eliminate Most Contagion. Is Most Enough? New Data – Brief19 AND Some Transmission of SARS-CoV-2 Occurs After Seven, 10 Days – Physician’s Wekly
Related (guideline and commentary): Why the CDC changed its Covid-19 quarantine guidelines
Commentary on Twitter
An ongoing CDC study of household spread of COVID-19 published in MWMR finds reducing quarantine to fewer than 14 days might be easier to comply with but carries some risk of spreading the virus. Learn more: https://t.co/3HCtyxCLiO pic.twitter.com/Frepnp0QRQ
— MMWR (@CDCMMWR) January 1, 2021
CDC Study: Among young, healthy athletes exposed to Covid-19, the probability of receiving positive test results after day 10 of quarantine is low (less than 5%)
12 Jan, 2021 | 02:01h | UTC
Commentary on Twitter
A new @CDCMMWR looking at college athletes exposed to #COVID19 supports giving health departments options to potentially shorten quarantine periods to increase adherence. Learn more: https://t.co/WuPF7MWtOF. pic.twitter.com/irsA0Zn7d7
— CDC (@CDCgov) January 7, 2021
Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms
12 Jan, 2021 | 01:38h | UTCAssociation of Fluoroquinolone Use With Short-term Risk of Development of Aortic Aneurysm – JAMA Surgery (free for a limited period)
Commentaries: Fluoroquinolones and Aortic Disease—Is It Time to Broaden the Warning? – JAMA (free for a limited period) AND Study links fluoroquinolones to higher risk of aneurysm – CIDRAP AND Analysis Links Fluoroquinolones to Increased Aortic Aneurysm Risk – Physician’s Weekly
Systematic Review: “For the general population of persons with elevated blood pressure, the benefits of trying to achieve a lower blood pressure target rather than a standard target (140/90 mm Hg or less) do not outweigh the harms associated with that intervention.”
12 Jan, 2021 | 01:30h | UTCBlood pressure targets in adults with hypertension – Cochrane Library
Summary: The use of lower blood pressure targets for people with hypertension – Cochrane Library
Related systematic review: Blood pressure targets in people with cardiovascular disease – Cochrane Library
Commentary on Twitter
The use of lower #bloodpressure targets for people with #hypertension https://t.co/W1bF8W7CDD Updated @CochraneHTN systematic review includes 11 randomised controlled trials involving 38,688 adult participants.
— Cochrane (@cochranecollab) December 30, 2020
New SARS-CoV-2 variants: increased transmissibility likely to cause more deaths and possibly a new wave of the disease
10 Jan, 2021 | 20:54h | UTC- SARS-CoV-2 Variants – World Health Organization
- Why epidemiologists are so worried about the new Covid-19 variants, in 2 charts – Vox
- We lost to SARS-CoV-2 in 2020. We can defeat B-117 in 2021 – STAT
- Transmission of SARS-CoV-2 Lineage B.1.1.7 in England: insights from linking epidemiological and genetic data – Imperial College of London AND Commentary: New COVID-19 variant growing rapidly in England – Imperial College London
- Genetic Variants of SARS-CoV-2—What Do They Mean? – JAMA
- Podcast: Understanding SARS-CoV-2 Genetic Variants – JAMA
- Podcast: Understanding the New SARS-CoV-2 Mutation Found in England – JAMA
- Viral mutations may cause another ‘very, very bad’ COVID-19 wave, scientists warn – Science
- Mutant coronavirus in the United Kingdom sets off alarms, but its importance remains unclear – Science
- New variant of SARS-CoV-2 in UK causes surge of COVID-19 – The Lancet Respiratory Medicine
- Scientists are monitoring a coronavirus mutation that could affect the strength of vaccines – STAT
- Instead of debating ‘first-shot’ vs. ‘set-aside’ vaccine approaches, hospitals’ study should compare them – STAT
- The Mutated Virus Is a Ticking Time Bomb – Vox
- What We Know About The New U.K. Variant Of Coronavirus — And What We Need To Find Out – NPR
- The New Mutations – Science Translational Medicine
- New Virus Strain’s Transmissibility to Cause More Deaths: Study – Bloomberg
- U.K. variant puts spotlight on immunocompromised patients’ role in the COVID-19 pandemic – Science
- When unusually severe COVID is seen, rapid identification-and-virus-sequencing are needed world-wide – Science Speaks: Global ID News
- Covid-19: New coronavirus variant is identified in UK – The BMJ
- The looming questions scientists need to answer about the new variant of the coronavirus – STAT
- With limited surveillance of Covid-19 variant, it’s déjà vu all over again – STAT
- New coronavirus variant: What do we know? – BBC
- Covid-19 in South Africa: Scientists seek to understand new variant – BBC
- New coronavirus variant: what is the spike protein and why are mutations on it important? – The Conversation
Long Covid: 6-month consequences of COVID-19 in patients discharged from hospital
10 Jan, 2021 | 20:43h | UTC6-month consequences of COVID-19 in patients discharged from hospital: a cohort study – The Lancet
Commentaries: Most patients hospitalized for Covid-19 still have symptoms six months later, China study finds AND Long-term follow-up of recovered patients with COVID-19 – The Lancet
Commentary on Twitter
Largest #LongCovid cohort @TheLancet just published:
6 months post-hospital,
—76% still had ≥ 1 symptom
—63% fatigue/muscle weakness
—sleep, anxiety, depression common
—Sig % w/CT lung abnormalities
—13% had abnormal kidney function https://t.co/zfRf7MGdxB pic.twitter.com/LI4DaJPis8— Eric Topol (@EricTopol) January 8, 2021
[Preprint] Characterizing Long COVID in an International Cohort: 7 Months of Symptoms and Their Impact
10 Jan, 2021 | 20:41h | UTCRelated: Explanations for ‘long Covid’ remain elusive. For now, believing patients and treating symptoms is the best doctors can do – STAT AND Long COVID: who is at risk? – The Conversation
Commentary on Twitter
How long is #LongCovid?
The most extensive symptom assessment and longest duration (7 months) of nearly 3,800 individuals shows how debilitating this is in young, predominantly women, w/ most unable to return to full prior work https://t.co/o0YUNse1EA @ahandvanish @AthenaAkrami pic.twitter.com/3miXJFdVp0— Eric Topol (@EricTopol) December 29, 2020
Randomized trial: Proton pump inhibitors do not benefit patients with persistent throat symptoms
10 Jan, 2021 | 20:32h | UTC
Commentary on Twitter
Medicating random throat symptoms with proton pump inhibitors (for months) has, somehow, become routine care despite no gd evidence it actually helps.
So guess what happens if you compare 16 wk of double dose PPI with placebo in a proper trial?
…Yeah.https://t.co/mrnq4tcEUk pic.twitter.com/uZo630Sg9j
— Jussi Mustonen (@JusiMD) January 8, 2021
AAP Guideline: Identification and management of eating disorders in children and adolescents
10 Jan, 2021 | 20:30h | UTCIdentification and Management of Eating Disorders in Children and Adolescents – Pediatrics
Commentary: Pediatrics Group Offers Guidance on Managing Eating Disorders in Youth – NEJM Journal Watch
Observational study: Childhood growth hormone treatment linked to increased risks of cardiovascular events in early adulthood
10 Jan, 2021 | 20:27h | UTCAssociation of Childhood Growth Hormone Treatment With Long-term Cardiovascular Morbidity – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Childhood Tx with Growth Hormone May Up Cardiovascular Risks Later – Physician’s Weekly AND Growth Hormones in Childhood Tied to Heart Problems Later On – MedPage Today (free registration required)
Study suggests that 7 days of home blood pressure monitoring is likely better than 24h ambulatory monitoring or 3 office measurements
10 Jan, 2021 | 20:17h | UTCEditorial: Which Blood Pressure Measurement Best Predicts Cardiovascular Outcomes?
Commentary: Is Home BP Monitoring the Best Approach For Diagnosing HTN? – American College of Cardiology
NICE Guideline: Managing the long-term effects of COVID-19
18 Dec, 2020 | 10:27h | UTC
NICE Guideline: Do not use Vitamin D to prevent or treat COVID 19
18 Dec, 2020 | 10:03h | UTCCOVID-19 rapid guideline: vitamin D – National Institute for Health and Care Excellence
News release: NICE, PHE and SACN publish rapid COVID-19 guidance on vitamin D
Commentaries: Covid and vitamin D: ‘Not enough evidence’ for treatment – BBC AND Covid-19: Evidence is lacking to support vitamin D’s role in treatment and prevention – The BMJ
Commentary on Twitter
https://twitter.com/onisillos/status/1339485382501666816
Vaccines are here. We have to talk about side effects
18 Dec, 2020 | 09:59h | UTCVaccines Are Here. We Have to Talk About Side Effects – Wired
Commentary on Twitter
All vaccines have side effects and trust comes from freely discussing them. Nice piece by @marynmck https://t.co/eUISXTiFVP
— Madhu Pai, MD, PhD (@paimadhu) December 17, 2020
“Racial Bias in Pulse Oximetry Measurement”. In two large cohorts, Black patients had nearly three times the frequency of occult hypoxemia that was not detected by pulse oximetry as White patients
18 Dec, 2020 | 10:01h | UTCRacial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
Commentary: Devices Used In COVID-19 Treatment Can Give Errors For Patients With Dark Skin – NPR
Commentary on Twitter (thread – click for more)
1/ Our research letter on racial bias in pulse oximetry measurement, out today in NEJM https://t.co/6dLuNGosxp pic.twitter.com/XXsfWfc5dv
— Michael Sjoding (@msjoding) December 17, 2020
Studies reveal deadliness of COVID-19, even in young adults
18 Dec, 2020 | 09:57h | UTCData reveal deadliness of COVID-19, even in young adults – CIDRAP
Survey: Around 1 in 5 COVID-19 patients exhibit symptoms for a period of 5 weeks or longer; Around 1 in 10 COVID-19 patients exhibit symptoms for a period of 12 weeks or longer
18 Dec, 2020 | 09:49h | UTCThe prevalence of long COVID symptoms and COVID-19 complications – Office of National Statistics
Commentary on Twitter
The prevalence of long COVID symptoms & COVID-19 complications published by @ONS
10% of covid positive patients exhibit symptoms for a period of > 12 weeks
20% for > 5 weeksGreat work by @DanAyoubkhani @Vnafilyan https://t.co/8YgxkCG847
@martinmckee pic.twitter.com/Itizxkk8xC
— Prof Kamlesh Khunti (@kamleshkhunti) December 17, 2020
CDC Guidelines for Gonococcal Infection, 2020. CDC recommends a single 500 mg intramuscular dose of ceftriaxone for uncomplicated gonorrhea, with oral doxycycline for 7 days when chlamydial coinfection has not been excluded
18 Dec, 2020 | 09:40h | UTCCommentary: CDC Guidelines Recommend Ceftriaxone Monotherapy for Uncomplicated Gonorrhea – NEJM Journal Watch
Commentary on Twitter
https://twitter.com/GarrettHile/status/1339732944613720064