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A WHO expert explains why she believes the rush for Covid-19 boosters is premature.

10 Aug, 2021 | 09:56h | UTC

A WHO expert explains why she believes the rush for Covid-19 boosters is premature – STAT

Commentary on Twitter

Must read interview on rich nations rushing into booster doses

Dr @Kate_L_OBrien by @HelenBranswell @statnews

"We really have huge inequity right now in just getting primary doses to people. Does a third dose need to be given?"https://t.co/pRhYwINuKf pic.twitter.com/YQS6Nj0Hyi

— Madhu Pai, MD, PhD (@paimadhu) August 9, 2021

Covid-19: How effective are vaccines against the delta variant?

10 Aug, 2021 | 10:00h | UTC

Covid-19: How effective are vaccines against the delta variant? – The BMJ

Study ties COVID vaccines to lower transmission rates.

10 Aug, 2021 | 09:51h | UTC

Study ties COVID vaccines to lower transmission rates – CIDRAP

Original study: Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021 – Eurosurveillance

‘Breakthrough’ infections do not mean COVID vaccines are failing.

10 Aug, 2021 | 09:54h | UTC

‘Breakthrough’ Infections Do Not Mean COVID Vaccines Are Failing – Scientific American

Commentary on Twitter

https://twitter.com/laurahelmuth/status/1422897892797337609

NICE Guideline | Management of Acne Vulgaris.

10 Aug, 2021 | 09:00h | UTC

Acne vulgaris: management – National Institute for Health and Care Excellence

ACOG Guideline: Access to postabortion contraception.

10 Aug, 2021 | 08:57h | UTC

Access to Postabortion Contraception: ACOG Committee Opinion, Number 833 – Obstetrics & Gynecology

Guideline: Endoscopy in patients on antiplatelet or anticoagulant therapy.

10 Aug, 2021 | 08:59h | UTC

Endoscopy in patients on antiplatelet or anticoagulant therapy: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guideline update – Endoscopy

Systematic Review: Non-invasive ventilation used at night by people with COPD.

10 Aug, 2021 | 08:53h | UTC

Summary: Non-invasive ventilation (ventilators) used at night by people with chronic obstructive pulmonary disease (COPD) – Cochrane Library

Original review: Chronic non‐invasive ventilation for chronic obstructive pulmonary disease – Cochrane Library

Secondary analysis of RCT finds Dapagliflozin is safe for patients with stage 4 chronic kidney disease.

10 Aug, 2021 | 08:51h | UTC

Effects of Dapagliflozin in Stage 4 Chronic Kidney Disease – Journal of the American Society of Nephrology

Commentaries:

Dapagliflozin Found Effective and Safe in Adults with Advanced Kidney Disease – American Society of Nephrology

No Increase in Risk With Dapagliflozin in Patients With Stage 4 CKD – HealthDay

Review: Diseases and complications of the puerperium.

10 Aug, 2021 | 08:46h | UTC

Diseases and Complications of the Puerperium – Deutsches Ärzteblatt International

Plant-based diets protective against CVD in two cohort studies.

10 Aug, 2021 | 08:48h | UTC

Plant-Based Diets Protective Against CVD in Two Studies – TCTMD

Original study 1: Relationship Between a Plant‐Based Dietary Portfolio and Risk of Cardiovascular Disease: Findings From the Women’s Health Initiative Prospective Cohort Study – Journal of the American Heart Association

Original study 2: Plant‐Centered Diet and Risk of Incident Cardiovascular Disease During Young to Middle Adulthood – Journal of the American Heart Association

Evidence-based approach to nailbed injuries: ED presentations, evaluation, and management.

10 Aug, 2021 | 08:47h | UTC

Evidence-based Approach to Nailbed Injuries: ED Presentations, Evaluation, and management – emDocs

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

9 Aug, 2021 | 00:06h | UTC

Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial – The Lancet

Invited commentary: Optimising SARS-CoV-2 vaccination schedules – The Lancet

Related: Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (several articles on the subject)

Commentary on Twitter

Just published @TheLancet
A randomized mix and match trial of AZ and Pfizer vaccination in >800 people shows that mixing is safe and can engender at least as good, if not better, immune response https://t.co/V40Dy59Ia8 by @XinxueLiu and colleagues pic.twitter.com/tKl59LFz4i

— Eric Topol (@EricTopol) August 6, 2021

Bullous autoimmune dermatoses: clinical features, diagnostic evaluation, and treatment options.

10 Aug, 2021 | 08:44h | UTC

Bullous Autoimmune Dermatoses – Deutsches Ärzteblatt International

CDC study showed a reduced risk of reinfection with SARS-CoV-2 after covid-19 vaccination.

9 Aug, 2021 | 00:03h | UTC

Reduced Risk of Reinfection with SARS-CoV-2 After COVID-19 Vaccination — Kentucky, May–June 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries on Twitter

This is non randomized. The two biases are:

1. Behavior among those who got vaccinated likely different than those who don't

2. Likely those who didn't tested more aggressively

I would not cite this as many are doinghttps://t.co/rSkBC37uq0

— Vinay Prasad MD MPH (@VPrasadMDMPH) August 7, 2021

Study shows that full #COVIDVaccination ⬇️ likelihood of being re-infected with #COVID19 compared to those who were previously had COVID but were not vaccinated (risk ⬆️ 2.3 fold)#GetVaccinated even if you have had COVID previouslyhttps://t.co/3dF3XPxwYp

@fascinatorfun pic.twitter.com/ip6zTvNN86

— Prof Kamlesh Khunti (@kamleshkhunti) August 7, 2021

M-A: SARS-CoV-2 Setting-specific transmission rates – “Households showed the highest transmission rates, with a pooled secondary attack rates of 21.1%”.

8 Aug, 2021 | 23:57h | UTC

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Setting-specific Transmission Rates: A Systematic Review and Meta-analysis – Clinical Infectious Diseases

Commentary on Twitter

SARS-CoV-2 setting-specific transmission rates: a systematic review and meta-analysis

Households highest transmission rates, pooled SAR~21.1%. Contacts at social events~5.9%. Workplaces~1.9%. Age gradient for transmission potential in h/hold context. https://t.co/m27kkDrTgy

— Andrew Lee is heading to @andrewleedr.bsky.social (@andrewleedr) March 10, 2021

More data showing one dose of Pfizer vaccine may be enough for individuals who’ve had COVID.

8 Aug, 2021 | 23:50h | UTC

Commentary: One Dose of Pfizer Vaccine May Be Enough for Folks Who’ve Had COVID – HealthDay

Original Study: SARS-CoV-2 Antibody Responses in Infection-Naive or Previously Infected Individuals After 1 and 2 Doses of the BNT162b2 Vaccine – JAMA Network Open

Perspective | Is one vaccine dose enough if you’ve had COVID? What the science says.

Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19

Spain to give just one vaccine dose to under 55-year olds who had COVID-19

Perspective: Is one vaccine dose enough after COVID-19 infection?

France’s health authority recommends single vaccine shot for people who have had COVID-19

Covid-19: People who have had infection might only need one dose of mRNA vaccine

Commentary on Twitter

SARS-CoV-2 Antibody Responses After 1 and 2 Doses of the BNT162b2 Vaccine https://t.co/ARMdH8Yboo via @JAMANetworkOpen part of @JAMANetwork Small study but one that confirms the policy of many European countries in which one dose of vaccine is sufficient after having COVID.

— Carlos del Rio (@CarlosdelRio7) August 7, 2021

Pediatric asthma: The REGAP consensus.

8 Aug, 2021 | 23:45h | UTC

Pediatric asthma: The REGAP consensus – Anales de Pediatría

M-A: Effect of low glycemic index or load dietary patterns on glycemic control and cardiometabolic risk factors in diabetes.

8 Aug, 2021 | 23:42h | UTC

Effect of low glycaemic index or load dietary patterns on glycaemic control and cardiometabolic risk factors in diabetes: systematic review and meta-analysis of randomised controlled trials – The BMJ

Commentary: Low glycaemic diet shows meaningful improvements for people with diabetes – The British Medical Journal

Commentary on Twitter

New #BMJResearch finds that low glycaemic index/glycaemic load dietary patterns provide small important benefits for glycaemic control and other established cardiometabolic risk factors in adults with moderately controlled type 1 and type 2 diabeteshttps://t.co/EIMXUhICee

— The BMJ (@bmj_latest) August 7, 2021