Family Medicine | Page 104 of 374 | Links Medicus Content Curation & Alerts in Medicine

The Paxlovid pill (Nirmatrelvir) randomized, placebo-controlled trial published @NEJM:
89% efficacy vs Covid hospitalizations or deaths, and quick reduction of viral load.
The active pills had less serious adverse events or discontinuations than placebohttps://t.co/HBMRZt4wBo pic.twitter.com/LDQv41O56c

— Eric Topol (@EricTopol) February 16, 2022

Meta-analysis finds the overall prevalence of statin intolerance is around 9% and identifies the most common risk factors.

17 Feb, 2022 | 10:07h | UTC

Prevalence of statin intolerance: a meta-analysis – European Heart Journal

Commentaries:

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10% – News Medical / European Society of Cardiology

Expert reaction to study looking at statin intolerance – Science Media Centre

Side effect patterns in a crossover trial of statin, placebo, and no treatment – This N-of-1 trial, now published in full, suggests the nocebo effect causes most of statins muscle adverse effects.

#AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo

Commentary on Twitter

Statin intolerance is “over-estimated and over-diagnosed”. World’s largest study shows less than 10% suffer side-effects caused by statins https://t.co/pcVk8YI3I3 @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes #CVD #Riskfactors pic.twitter.com/b3nFWsc74d

— European Society of Cardiology Journals (@ESC_Journals) February 16, 2022

England to offer Covid jab to five to 11-year-olds.

17 Feb, 2022 | 10:09h | UTC

England to offer Covid jab to five to 11-year-olds – BBC

Perspective | The hidden epidemic: Antibiotic resistance is approaching a crisis point, and the world needs to act.

17 Feb, 2022 | 08:39h | UTC

The Hidden Epidemic – Vox

Treatment options after a diagnosis of early miscarriage: expectant, medical, and surgical.

17 Feb, 2022 | 08:24h | UTC

Treatment Options After a Diagnosis of Early Miscarriage: Expectant, Medical, and Surgical – Deutsches Ärzteblatt International

Time for united action on depression: a Lancet–World Psychiatric Association Commission.

16 Feb, 2022 | 10:18h | UTC

Homepage: Time for united action on depression: a Lancet–World Psychiatric Association Commission – The Lancet

Editorial: Ensuring care for people with depression (free registration required)

Commission: Time for united action on depression: a Lancet–World Psychiatric Association Commission (free registration required)

News Release: Overlooked and underfunded—experts call for united action to reduce the global burden of depression – The Lancet

Commentary on Twitter

Depression is overlooked & underfunded.

New Lancet-@WPA_Psychiatry Commission calls for whole-of-society approach to alleviate one of the world's leading causes of avoidable suffering & premature deaths. #UniteAgainstDepression

➡️ https://t.co/0NxPbhGAlY pic.twitter.com/b4nG9YvbaH

— The Lancet (@TheLancet) February 15, 2022

Development of a metric to detect and decrease low-value prescribing in older adults.

16 Feb, 2022 | 09:58h | UTC

Development of a Metric to Detect and Decrease Low-Value Prescribing in Older Adults – JAMA Network Open

Invited Commentary: Considering Value in Prescribing and Deprescribing for Older Adults – JAMA

Commentary on Twitter

In this qualitative study, a scientifically valid and clinically useful low-value prescribing metric was built. EVOLV-Rx may enhance the detection of low-value prescribing practices, reduce polypharmacy, and enable older adults to receive high-value care. https://t.co/GtrsUboT9o

— JAMA Network Open (@JAMANetworkOpen) February 15, 2022

Seminar: Measles.

16 Feb, 2022 | 10:15h | UTC

Measles – The Lancet (free registration required)

WHO Questions and Answers: COVID-19 vaccines and pregnancy.

16 Feb, 2022 | 09:53h | UTC

Questions and Answers: COVID-19 vaccines and pregnancy – World Health Organization

COVID vaccines safely protect pregnant people: the data are in.

COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

Commentary on Twitter

🆕 Summary of WHO recommendations on #COVID19 vaccination in pregnancy https://t.co/XPVggBbSmj

If you’re pregnant, vaccination is one of the most important ways to protect yourself and your baby from severe illness from COVID-19. pic.twitter.com/dfSBVJLBG7

— World Health Organization (WHO) (@WHO) February 15, 2022

M-A: Global prevalence of meeting screen time guidelines among children 5 years and younger.

16 Feb, 2022 | 08:40h | UTC

Global Prevalence of Meeting Screen Time Guidelines Among Children 5 Years and Younger: A Systematic Review and Meta-analysis – JAMA Pediatrics

Commentary: Kids using screens more than recommended, new study finds – ABC News

Related Guidelines:

Media and Young Minds – American Academy of Pediatrics

Guidelines on Screen Time and Digital Wellness in Infants, Children and Adolescents – “children below 2 years age should not be exposed to any type of screen, whereas exposure should be limited to a maximum of one hour of supervised screen time per day for children 24-59 months age, and less than two hours per day for children 5-10 years age”.

Commentary on Twitter

A meta-analysis led by @BraeMcArthur and @sherimadigan found that globally, 24.7% of children under 2 met the guideline to avoid screen use and 35.6% of children 2-5 years meet the guideline of no more than 1hr/day. https://t.co/faJ5oWZ70k

— JAMA Pediatrics (@JAMAPediatrics) February 14, 2022

Podcast | Failure to Thrive – Growing into Focused Management.

16 Feb, 2022 | 08:34h | UTC

#39: Failure to Thrive – Growing into Focused Management – The Cribsiders

Podcast | Hypertension FAQ: Common Outpatient Cases.

16 Feb, 2022 | 08:36h | UTC

#321 Hypertension FAQ: Common Outpatient Cases with Dr. Jordy Cohen – The Curbsiders

ACR Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV-2 and Hyperinflammation in Pediatric COVID-19.

15 Feb, 2022 | 10:17h | UTC

American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS–CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 3 – Arthritis & Rheumatism

Commentary and summary: ACR Updates Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With COVID – RheumNow

Why don’t most people with COVID need to test for another 30 days, even if they’re re-exposed?

15 Feb, 2022 | 10:14h | UTC

Why don’t most people with COVID need to test for another 30 days, even if they’re re-exposed? – The Conversation

Retrospective Cohort: Association of SARS-CoV-2 infection with serious maternal morbidity and mortality from obstetric complications.

15 Feb, 2022 | 10:11h | UTC

Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications – JAMA

News Release: NIH-funded study suggests COVID-19 increases risk of pregnancy complications – NIH News Releases

Commentary on Twitter

In this study, among pregnant and postpartum individuals, #SARSCoV2 infection was associated with increased risk of a composite outcome of maternal mortality or serious morbidity from obstetric complications. https://t.co/51wcT8GhJq

— JAMA (@JAMA_current) February 7, 2022