Evidence-based Medicine
Structured reporting to improve transparency of analyses in prognostic marker studies.
10 Jun, 2022 | 10:29h | UTCStructured reporting to improve transparency of analyses in prognostic marker studies – BMC Medicine
Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis.
9 Jun, 2022 | 10:36h | UTCSensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis – Eye
See Special Series: Research Methodology for the Ophthalmologist – Eye
‘Helicopter research’ comes under fire at Cape Town conference – statement presses for equity when scientists from wealthy nations do research in poorer ones.
8 Jun, 2022 | 11:11h | UTC‘Helicopter research’ comes under fire at Cape Town conference – Science
Do we need to reconsider how we design and conduct randomized controlled trials?
8 Jun, 2022 | 10:56h | UTC
#ADA2022 – RCT: Tirzepatide once weekly for the treatment of obesity.
6 Jun, 2022 | 11:59h | UTCTirzepatide Once Weekly for the Treatment of Obesity – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
SURMOUNT-1: In an RCT, adults with obesity treated with weekly tirzepatide had major weight loss over 72 weeks. #ADA2022 https://t.co/X2RrvYxzsV pic.twitter.com/X27bWp1Qod
— NEJM (@NEJM) June 4, 2022
Pivot into COVID-19 research eases as publishing surge starts to level off – Researchers who jumped into the field from distant disciplines published lower impact work, study finds.
27 May, 2022 | 12:18h | UTCPivot into COVID-19 research eases as publishing surge starts to level off – Science
Top studies of 2021 relevant to primary care.
26 May, 2022 | 10:55h | UTCTop studies of 2021 relevant to primary care: From the PEER team – Canadian Family Physician
Practical guidance to qualitative research. Part 6: Longitudinal qualitative and mixed-methods approaches for longitudinal and complex health themes in primary care research.
26 May, 2022 | 10:15h | UTCOther articles in the series:
Series: Practical guidance to qualitative research. Part 1: Introduction
Series: Practical guidance to qualitative research. Part 2: Context, research questions and designs
Series: Practical guidance to qualitative research. Part 3: Sampling, data collection and analysis
Series: Practical guidance to qualitative research. Part 4: Trustworthiness and publishing
Creating effective infographics and visual abstracts to disseminate research and facilitate medical education on social media.
24 May, 2022 | 10:46h | UTC
Commentary on Twitter
Creating Effective Infographics and Visual Abstracts to Disseminate Research and Facilitate Medical Education on Social Media
? Freely Available
? https://t.co/GpeoEQAWMP#IDTwitter
via @JenniferSpicer4 and @cg_coleman pic.twitter.com/DjiJbAyPVQ— Clinical Infectious Diseases (@CIDJournal) May 23, 2022
Opinion: How to pick a great scientific collaborator.
24 May, 2022 | 07:56h | UTCHow to pick a great scientific collaborator – Nature
Clinical trial registration patterns and changes in primary outcomes of randomized clinical trials from 2002 to 2017.
23 May, 2022 | 01:34h | UTCClinical Trial Registration Patterns and Changes in Primary Outcomes of Randomized Clinical Trials From 2002 to 2017 – JAMA Internal Medicine (free for a limited period)
Commentary on Twitter
This study of 146,462 full-text RCTs found that up to 32% of published trials reported a registry number, and almost 15% of these made substantial changes in primary outcome registration within study duration. Practices have improved over the years. https://t.co/JnXrEpp00J
— JAMA Internal Medicine (@JAMAInternalMed) May 17, 2022
Viewpoint: The imperative for diversity and inclusion in clinical trials and health research participation.
23 May, 2022 | 00:49h | UTC
Perspective: The need for increased pragmatism in cardiovascular clinical trials.
19 May, 2022 | 10:48h | UTCThe need for increased pragmatism in cardiovascular clinical trials – Nature Reviews Cardiology (if the link is paywalled, try this one)
Related: A roadmap of strategies to support cardiovascular researchers: from policy to practice – Nature Reviews Cardiology (if the link is paywalled, try this one)
Commentary on Twitter
In our latest Review, @ShahzebKhanMD and colleagues discuss the need for increased pragmatism in #cardiovascular clinical trials: https://t.co/LUlrPKusAk pic.twitter.com/cxAYmD2nyS
— Nature Reviews Cardiology (@NatRevCardiol) May 17, 2022
Reporting guideline for the early stage clinical evaluation of decision support systems driven by artificial intelligence: DECIDE-AI.
19 May, 2022 | 10:45h | UTC
Study designs for clinical trials applied to personalized medicine: a scoping review.
19 May, 2022 | 10:36h | UTCStudy designs for clinical trials applied to personalised medicine: a scoping review – BMJ Open
Perspective: One statistical analysis must not rule them all.
18 May, 2022 | 10:52h | UTCOne statistical analysis must not rule them all – Nature
Videos: The ROB-MEN tool to evaluate the risk of bias due to missing evidence in network meta-analysis.
18 May, 2022 | 10:43h | UTC
Commentary on Twitter
New videos from the #cochranelearninglive webinar series on The ROB-MEN tool to evaluate the risk of bias due to missing evidence in network meta-analysis. Resources freely available at https://t.co/Sfr6sq1Wmy@cochranecollab pic.twitter.com/FgPMasMLdG
— Cochrane Training (@cochranetrain) May 12, 2022
Visualizing harms in publications of randomized controlled trials: consensus and recommendations.
17 May, 2022 | 10:47h | UTCCommentary: Visualising harms: barely scratching the surface – The BMJ
A roadmap of strategies to support cardiovascular researchers: from policy to practice.
17 May, 2022 | 10:34h | UTCA roadmap of strategies to support cardiovascular researchers: from policy to practice – Nature Reviews Cardiology (if the link is paywalled, try this one)
Commentary on Twitter (thread – click for more)
Excited to share this major piece of work from the inaugural @OzCvA Emerging Leaders Committee:
A roadmap for developing a supportive & sustainable cardiovascular research sector published in @NatRevCardiol https://t.co/sjWahzkGD6
A ?
— ???A/Prof Francine Marques (@FZMarques) May 16, 2022
Review: Clinical trials in older people.
13 May, 2022 | 11:02h | UTCClinical trials in older people – Age and Ageing
Sci-Hub downloads show countries where pirate paper site is most used.
13 May, 2022 | 10:47h | UTCSci-Hub downloads show countries where pirate paper site is most used – Nature
Opinion: Why preprints are good for patients.
12 May, 2022 | 10:25h | UTCWhy preprints are good for patients – Nature Medicine
Commentary on Twitter
.@PeterHorby on how rapid communication saved lives. "In the month between the public announcement of the [RECOVERY dexamethasone] result and the publication of the peer-reviewed manuscript, over 700,000 [new] COVID-19 cases were reported globally."https://t.co/5m3VVxjBBX
— Natalie E. Dean, PhD (@nataliexdean) May 11, 2022
Nonregistration, discontinuation, and nonpublication of randomized trials: A repeated metaresearch analysis.
12 May, 2022 | 08:08h | UTC
Non-Inferiority Trials: Understanding the concepts.
1 May, 2022 | 23:33h | UTCNon-Inferiority Trials: Understanding the Concepts – Students 4 Best Evidence
Related:
Non-inferiority trials in cardiology: what clinicians need to know – Heart
Collider bias in observational studies: consequences for medical research.
1 May, 2022 | 23:12h | UTC