Endocrinology (all articles)
Cohort Study: Higher Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes
20 Sep, 2018 | 19:43h | UTCHigher Whole-Grain Intake Is Associated with Lower Risk of Type 2 Diabetes among Middle-Aged Men and Women: The Danish Diet, Cancer, and Health Cohort – The Journal of Nutrition (link to abstract – $ for full-text)
Commentary: What you need to know about claims that whole grains can prevent diabetes – Health News Review (free)
Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly
20 Sep, 2018 | 19:25h | UTCEffect of Aspirin on All-Cause Mortality in the Healthy Elderly – New England Journal of Medicine (free) (via @EricTopol)
Related Studies: Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly – New England Journal of Medicine (free) AND Effect of Aspirin on Disability-free Survival in the Healthy Elderly – New England Journal of Medicine (free)
Commentaries: Daily low-dose aspirin found to have no effect on healthy life span in older people- NIH News Releases (free) AND Low-Dose Aspirin Late in Life? Healthy People May Not Need It – The New York Times (10 articles per month are free)
Guideline for the Management of Graves’ Hyperthyroidism
14 Sep, 2018 | 01:35h | UTC2018 European Thyroid Association Guideline for the Management of Graves’ Hyperthyroidism – European Thyroid Journal (free) (via @CristobMorales and @Abraham_RMI)
Study: Statins for Primary Prevention in Old and Very Old Adults
14 Sep, 2018 | 01:26h | UTCEditorial: Primary prevention with statins for older adults (free)
Commentaries: Expert reaction to study on use of statins in older people – Science Media Centre (free) AND Widespread use of statins in healthy older people to prevent heart disease not recommended in new study – BMJ, via ScienceDaily (free)
“New research does not support widespread use of statins in healthy older people to prevent heart disease and stroke. Results found that any protective effect was limited to those with type 2 diabetes aged between 75 and 84” (via @bmj_latest see Tweet)
WHO Guideline: Medicines for the Treatment of Diabetes in Low-Resource Settings
6 Sep, 2018 | 02:42h | UTCOriginal Guideline: Guidelines on second-and third-line medicines and type of insulin for the control of blood glucose levels in non-pregnant adults with diabetes mellitus – World Health Organization (free PDF)
Review: Risk Stratification on Pheochromocytoma and Paraganglioma from Laboratory and Clinical Medicine
2 Sep, 2018 | 02:06h | UTC
Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes
31 Aug, 2018 | 03:07h | UTCEffects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus – New England Journal of Medicine (free for a limited period)
Commentaries: Bleeds and benefit with aspirin balanced in patients with diabetes and no effect on cancer – ESC Press Releases (free) AND ASCEND: Aspirin Doesn’t Look Good for Primary CV Prevention in Diabetic Patients – TCTMD (free)
Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease
31 Aug, 2018 | 03:06h | UTCUse of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Aspirin Fails to Prevent CV Events in People at ‘Moderate’ Risk of Disease: ARRIVE – TCTMD (free) AND ARRIVE: New Findings Contribute to Growing Body of Evidence Surrounding Aspirin Use – American College of Cardiology (free) AND Daily Aspirin Fails to Lower CV Risk in Long-term, Primary Prevention ARRIVE Trial – Medscape (free registration required) AND Jury still out on aspirin a day to prevent heart attack and stroke – ESC Press Releases (free)
Randomized Trial: Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus
31 Aug, 2018 | 02:58h | UTCEffects of n−3 Fatty Acid Supplements in Diabetes Mellitus – New England Journal of Medicine (free for a limited period)
Commentaries: Fish oils do not prevent heart attack or strokes in people with diabetes – ESC News Releases (free) AND Omega-3 Fatty Acids Fail to Reduce CVD Events in Diabetic Patients: ASCEND – TCTMD (free)
Related Cochrane Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (link to abstract and commentaries)
Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free study and commentary)
Study: Vitamin D Not Linked to Fracture Risk
31 Aug, 2018 | 02:43h | UTCCommentaries: Vitamin D: a pseudo-vitamin for a pseudo-disease – The Conversation (free) AND Fracture risk not linked to low vitamin D or calcium levels – OnMedica (free)
Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline)
Randomized Trial: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients
31 Aug, 2018 | 01:58h | UTCCardiovascular Safety of Lorcaserin in Overweight or Obese Patients – New England Journal of Medicine (free for a limited period)
Editorial: Lorcaserin — Elixir or Liability? (free for a limited period)
Commentaries: CAMELLIA-TIMI 61: Weight Loss Drug Lorcaserin Did Not Increase CV Events – American College of Cardiology (free) AND Weight-Loss Drug Lorcaserin Clears Cardiovascular Safety Hurdle: CAMELLIA-TIMI 61 – TCTMD (free) AND Weight loss drug lorcaserin found safe in large study – Reuters (free)
Guiding Principles for the Care of People with or at Risk for Diabetes
31 Aug, 2018 | 02:00h | UTCCommentaries: NIDDK Updates ‘Guiding Principles’ for Diabetes, Prediabetes – Medscape (free registration required) AND NDEP revises principles for managing diabetes, prediabetes – Cardiovascular Business (free)
Related Book: Diabetes in America, 3rd Edition – National Institutes of Health (free reference book, just released)
Cohort Study: Long-Term Association of LDL Cholesterol With Cardiovascular Mortality in Low-Risk Individuals
23 Aug, 2018 | 23:22h | UTCCommentaries: ‘Bad’ cholesterol can be deadly in otherwise healthy people – AHA News (free) AND LDL >160 Tied to Increased Mortality in Low-Risk Patients – Physician’s First Watch (free) AND Study: Elevated LDL, non-HDL increase CVD mortality risk in young, healthy individuals – Cardiovascular Business (free) AND Moderate ‘bad cholesterol’ levels tied to early death for healthy people – Reuters (free)
Perspective: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It
23 Aug, 2018 | 22:32h | UTCVitamin D, the Sunshine Supplement, Has Shadowy Money Behind It – The New York Times (10 articles per month are free) (via @CarlosdelRio7 see Tweet)
Related commentaries: Vitamin D Screening and Supplementation in Primary Care: Time to Curb Our Enthusiasm – American Family Physician (free) AND Your vitamin D tests and supplements are probably a waste of money – VOX (free) AND Why Are So Many People Popping Vitamin D? – The New York Times (10 articles per month are free)
Related Guideline: Vitamin D: supplement use in specific population groups – National Institute for Health and Care Excellence (free)
“Only test vitamin D status if someone has symptoms of deficiency or is at very high risk” (from NICE Guideline)
Study: Association of Body Mass Index With Blood Pressure
23 Aug, 2018 | 22:26h | UTCCommentary: As body mass index increases, blood pressure may as well – Yale University (free)
Cohort Studies: Smoking Cessation, Weight Change, Type 2 Diabetes, and Mortality
17 Aug, 2018 | 02:35h | UTCSmoking Cessation, Weight Change, Type 2 Diabetes, and Mortality – The New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Weight gain after smoking cessation linked with increased short-term diabetes risk – Harvard T.H. Chan School of Public Health (free) AND Weight gain temporarily hikes diabetes risk when smokers quit – Reuters (free) AND Smokers Are Better Off After They Quit Even if They Gain Weight – Physician’s First Watch (free)
Cohort Study: Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes
17 Aug, 2018 | 02:26h | UTCRisk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: In Type 2 Diabetes, Five Risk Factor Targets Keep MI, Stroke, and Death in Check – TCTMD (free) AND How People With Type 2 Diabetes Can Lower Their Risk of Health Problems – TIME (free) AND T2D, Without Other Risks, Not Tied to Excess Mortality – MedPage Today (free registration required)
Study: Polygenic Scores for Common Diseases Identify Individuals with Risk Equivalent to Monogenic Mutations
17 Aug, 2018 | 02:09h | UTCGenome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations – Nature Genetics (link to abstract – $ for full-text)
Commentaries: Researchers predict risk for common deadly diseases from millions of genetic variants – Broad Institute of MIT and Harvard, ScienceDaily (free) AND Clues to Your Health Are Hidden at 6.6 Million Spots in Your DNA – The New York Times (10 articles per month are free) AND Multi-gene test may find risk for heart disease and more – Associated Press (free) AND A Harvard Scientist Thinks He Has a Gene Test for Heart Attack Risk. He Wants to Give It Away Free – Forbes (free)
Book: Diabetes in America, 3rd Edition – National Institutes of Health
17 Aug, 2018 | 02:01h | UTCDiabetes in America, 3rd Edition – National Institutes of Health (free chapters)
News Release: New NIH reference book is one-stop resource for diabetes medical information – National Institutes of Health (free)
Systematic Reviews: Treatments for Women with Gestational Diabetes Mellitus
17 Aug, 2018 | 02:00h | UTCTreatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews – Cochrane Library (free)
Cohort Study: Excess Mortality and Cardiovascular Disease in Young Adults With Type 1 Diabetes in Relation to Age at Onset
17 Aug, 2018 | 01:44h | UTCExcess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study – The Lancet (link to abstract – $ for full-text)
Commentaries: Early type 1 diabetes shortens women’s lives by 18 years – University of Gothenburg, via ScienceDaily (free) AND Early age type 1 diabetes linked to shorter life expectancy than later age diagnosis – OnMedica (free)
Study: Nuts as a Replacement for Carbohydrates in the Diabetic Diet
16 Aug, 2018 | 23:10h | UTC
Study: Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes
16 Aug, 2018 | 23:09h | UTCSex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data – Diabetes Care (link to abstract – $ for full-text)
Commentary: Doctors should use gender and body mass to personalise diabetes care, study says – The Irish News (free)
Source: The BMJ Research News ($)
Guideline: Management of Adrenocortical Carcinoma in Adults
16 Aug, 2018 | 23:08h | UTCEuropean Society of Endocrinology Clinical Practice Guidelines on the Management of Adrenocortical Carcinoma in Adults, in collaboration with the European Network for the Study of Adrenal Tumors – European Journal of Endocrinology (free PDF)
AHA Scientific Statement: Approaches to the Prevention and Management of Childhood Obesity
11 Aug, 2018 | 02:25h | UTCNews release: New tools, old rules: limit screen-based recreational media at home – AHA/ASA Newsroom (free)