Endocrinology (all articles)
Cohort Study: Metformin Safe for Many Patients with Chronic Kidney Disease
7 Jun, 2018 | 02:49h | UTCAssociation of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Study Supports Metformin Use at eGFRs as Low as 30 – NEJM Physician’s First Watch (free) AND Metformin safe for most diabetics with kidney disease – UPI (free) AND Evidence Growing Metformin Safe in Many With Diabetes and CKD – Medscape (free registration required)
Related Studies: Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease (link to abstract and commentaries) AND Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF – ACP Diabetes Monthly (free)
Research: New Risk Calculator Estimates Millions are Being Overtreated with Statins
7 Jun, 2018 | 02:42h | UTCClinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: New risk calculator could change the aspirin, statins, and blood pressure medications some people take – STAT (free) AND Statin recommendations may change, especially for African-Americans – CNN (free) AND Millions could have incorrect statin, aspirin and blood pressure prescriptions – Stanford Medicine, via ScienceDaily (free) AND Current models overestimate CVD risk of 11.8M US adults – Cardiovascular Business (free)
Position Statement: Guidance for People with Types 1 and 2 Diabetes Who Fast During Ramadan
1 Jun, 2018 | 04:36h | UTC
Perspective: For Patients with Type 2 Diabetes, What’s the Best Target Hemoglobin A1C?
1 Jun, 2018 | 04:36h | UTCFor Patients With Type 2 Diabetes, What’s the Best Target Hemoglobin A1C? – JAMA (free for a limited period)
Related: A1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks – Diabetes Care (free) AND Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)
Guideline: Type 2 Diabetes Mellitus in Older People
1 Jun, 2018 | 03:48h | UTCCommentary: New guidance on treating diabetes in elderly and frail adults – University of Exeter, via EurekAlert (free)
Cohort Study: Association Between Food Insecurity and Incident Type 2 Diabetes
29 May, 2018 | 18:14h | UTCCommentary: Food insecurity linked to type 2 diabetes risk – Reuters (free)
“Canadians who cannot afford to eat regularly or to eat a healthy diet have more than double the average risk of developing type 2 diabetes” (from Reuters)
Editorial: A1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks
28 May, 2018 | 12:54h | UTCA1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks – Diabetes Care (free) (via @Abraham_RMI)
Related guideline: Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)
“Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with type 2 diabetes” (from ACP Guideline, prompting the Editorial)
Cohort Study: Weight Gain with Antidepressant Utilization
28 May, 2018 | 12:38h | UTCEditorial: Antidepressant induced weight gain (free)
Commentaries: Antidepressant therapy and risk of weight gain – The BMJ Opinion (free) AND Taking antidepressants could be linked to weight gain, according to a new study — and some drugs heighten the risk more than others – Business Insider (free) AND Antidepressants linked to risk of weight gain, study shows – OnMedica (free) AND Antidepressant use linked with weight gain – NHS Choices (free)
Review: Pitfalls on the Replacement Therapy for Hypothyroidism
24 May, 2018 | 23:13h | UTC
Meta-Analysis: Longitudinal Association Between Diabetes and Anxiety
24 May, 2018 | 22:57h | UTCInvestigating the longitudinal association between diabetes and anxiety: a systematic review and meta‐analysis – Diabetic Medicine (free) (via @kamleshkhunti)
Randomized Trial: Effectiveness of Text Message Based, Diabetes Self-management Support
24 May, 2018 | 22:19h | UTCCommentaries: The potential of mobile health—reaching those in need – The BMJ Opinion (free)
Cohort Study: Egg Consumption and Cardiovascular Disease
23 May, 2018 | 12:32h | UTCCommentaries: BMJ’s scrambled message on eggs and heart disease: a recipe for rotten news coverage – Health News Review (free) AND Expert reaction to eggs and CVD – Science Media Centre (free) AND No, Eating Eggs Will NOT Protect You From Cardiovascular Death – The Methods Man (free)
Guideline Summary: CVD and Risk Management Standards in Diabetes
21 May, 2018 | 13:20h | UTCSummary with Key Points: CVD and Risk Management Standards in Diabetes – American College of Cardiology (free)
Original Synopsis: Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018 – Annals of Internal Medicine (free)
Review: Pitfalls on the Replacement Therapy for Hypothyroidism
21 May, 2018 | 13:03h | UTC
Randomized Trial: Effectiveness of Text Message Based, Diabetes Self-Management Support Program
21 May, 2018 | 12:58h | UTCCommentary: The potential of mobile health—reaching those in need – The BMJ Opinion (free)
Consensus: Adverse Effects of Statin Therapy
18 May, 2018 | 02:34h | UTCCommentary: EAS Consensus Document Examines Safety of Statins Beyond Muscle Symptoms – TCTMD (free)
Position Paper: Some Calories More Harmful Than Others
16 May, 2018 | 01:20h | UTCCommentary: Some calories more harmful than others – University of California, via EurekAlert (free)
Retrospective Cohort: Achieved Systolic BP and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus
16 May, 2018 | 00:35h | UTCEffect of Achieved Systolic Blood Pressure on Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus: A Population-Based Retrospective Cohort Study – Diabetes Care (link to abstract – $ for full-text)
Commentaries: Diabetics with lower achieved SBP may be at greater risk for cardiovascular disease – Cardiovascular Business (free) AND No reduced CVD risk for SBP <120 mm hg in type 2 diabetes – MedicalXpress (free)
Cluster-Randomized, Crossover Study: Continuous Glucose Monitoring for Glycemic Control in ICU Patients
14 May, 2018 | 11:30h | UTCNear-Continuous Glucose Monitoring Makes Glycemic Control Safer in ICU Patients – Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Hypoglycemia reduced with continuous glucose monitoring in small trial of ICU patients – ACP Diabetes (free)
Randomized Controlled Trial: High-Dose vs. Low-Dose Statin in Stable Coronary Artery Disease
10 May, 2018 | 17:55h | UTCWith a median follow-up of 3.9 years, high-dose as compared with low-dose pitavastatin significantly reduced the risk of the primary end point (4.3% vs 5.4%; NNT = 90), a composite of cardiovascular death, nonfatal myocardial infarction, nonfatal ischemic stroke, or unstable angina requiring emergency hospitalization.
Observational Study: Management of Type 1 Diabetes With a Very Low–Carbohydrate Diet
10 May, 2018 | 17:39h | UTCManagement of Type 1 Diabetes With a Very Low–Carbohydrate Diet – Pediatrics (free)
Commentaries: How Low Can You Go? Does Lower Carb Translate to Lower Glucose? – Pediatrics (free) AND Very-low-carb diet shows promise in type 1 diabetes – Boston Children’s Hospital, via ScienceDaily (free) AND How a Low-Carb Diet Might Aid People With Type 1 Diabetes – The New York Times (10 articles per month are free) AND Is Exceptional Control of Type 1 Diabetes Possible with a Low-Carbohydrate Diet? – Dr. David Ludwig Blog (free)
*Randomized controlled trials are warranted.
Position Statement: Type 2 diabetes and Heart Failure
10 May, 2018 | 17:34h | UTC
Short Review: Managing Dyslipidemia in Primary Prevention
9 May, 2018 | 16:21h | UTCManaging Dyslipidemia in Primary Prevention – American College of Cardiology (free)
Review: Obesity Emergency Management
9 May, 2018 | 16:20h | UTCEM Cases: Obesity Emergency Management – emDocs (free)
Randomized Controlled Trial: Glyburide vs Insulin for the Treatment of Gestational Diabetes
3 May, 2018 | 20:04h | UTCEffect of Glyburide vs Subcutaneous Insulin on Perinatal Complications Among Women With Gestational Diabetes: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: Glyburide Should Not Be First-Line for Gestational Diabetes – Medscape (free registration required) AND Glyburide Compared With Insulin for First-Line Tx of Gestational Diabetes – MPR (free)