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Endocrinology (all articles)

Consensus Statement | Comprehensive type 2 diabetes management algorithm – 2023 update

9 May, 2023 | 15:10h | UTC

American Association of Clinical Endocrinology Consensus Statement: Comprehensive Type 2 Diabetes Management Algorithm – 2023 Update – Endocrine Practice

Related: Guideline | ADA 2023 Standards of Medical Care in Diabetes

 


Consensus | Addressing stigma/bias in diagnosing, managing obesity-based chronic disease, and evaluating determinants of severity

9 May, 2023 | 15:08h | UTC

American Association of Clinical Endocrinology Consensus Statement: Addressing Stigma and Bias in the Diagnosis and Management of Patients with Obesity/Adiposity-Based Chronic Disease and Assessing Bias and Stigmatization as Determinants of Disease Severity – Endocrine Practice

 


RCT | Early treatment of gestational diabetes slightly lowers risk of adverse neonatal outcomes

9 May, 2023 | 14:55h | UTC

Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Early treatment of gestational diabetes for those at higher risk beneficial, study finds – Western Sidney University

 


Review | Syndrome of inappropriate antidiuresis: from pathophysiology to management

9 May, 2023 | 14:37h | UTC

Syndrome of Inappropriate Antidiuresis: From Pathophysiology to Management – Endocrine Reviews


Metformin: update on mechanisms of action and repurposing potential

8 May, 2023 | 13:05h | UTC

Metformin: update on mechanisms of action and repurposing potential – Nature Reviews Endocrinology (if the link is paywalled, try this one in PMC)

 

Commentary on Twitter

 


Evidence-based recommendations for the dietary management of diabetes

8 May, 2023 | 12:56h | UTC

Evidence-based European recommendations for the dietary management of diabetes – Diabetologia (if the link is paywalled, try this one)

 


Consensus Statement | Homozygous Familial Hypercholesterolemia: new treatments and clinical guidance

5 May, 2023 | 14:58h | UTC

2023 Update on European Atherosclerosis Society Consensus Statement on Homozygous Familial Hypercholesterolaemia: new treatments and clinical guidance – European Heart Journal

 


Cohort Study | Comparison of propylthiouracil vs. methimazole for thyroid storm in critically ill patients

4 May, 2023 | 13:47h | UTC

Comparison of Propylthiouracil vs Methimazole for Thyroid Storm in Critically Ill Patients – JAMA Network Open

News Release: Study: No significant differences in mortality, adverse events in patients taking thyroid medications – Boston University

 


SR | In people with prediabetes, Vitamin D may have a small benefit in decreasing the risk of diabetes

4 May, 2023 | 13:28h | UTC

Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes: A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries:

Expert reaction to study looking at vitamin D supplementation and reduction in diabetes risk – Science Media Centre

How Helpful Is Vitamin D in Prediabetes? – ConscienHealth

 


RCT | Best endovascular treatment first strategy yields better outcomes for chronic limb ischemia vs. vein bypass first strategy

3 May, 2023 | 15:39h | UTC

A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-popliteal, with or without an additional more proximal infra-inguinal revascularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial – The Lancet

Commentary: BASIL-2 Supports Endo-First Strategy for CLTI With Infrapopliteal Disease – TCTMD

 


M-A | Efficacy of osteoporosis interventions on fracture prevention in postmenopausal women

3 May, 2023 | 15:37h | UTC

Fracture risk reduction and safety by osteoporosis treatment compared with placebo or active comparator in postmenopausal women: systematic review, network meta-analysis, and meta-regression analysis of randomised clinical trials – The BMJ

 


Cohort Study | Beverage consumption and mortality among adults with type 2 diabetes

26 Apr, 2023 | 14:09h | UTC

Beverage consumption and mortality among adults with type 2 diabetes: prospective cohort study – The BMJ

Editorial: Beverages and health outcomes in adults with type 2 diabetes – The BMJ

Commentary: Healthy Beverage Choices May Lower Mortality Risk in Adults with Diabetes – HCP Live

 


Brief Review | Diagnosis and management of adrenal insufficiency

25 Apr, 2023 | 14:18h | UTC

Diagnosis and management of adrenal insufficiency – Clinical Medicine Journal

 


Brief Review | Diagnosis and management of neuroendocrine tumors

25 Apr, 2023 | 14:16h | UTC

Diagnosis and management of neuroendocrine tumours – Clinical Medicine Journal

 


Brief Review | Management of pituitary incidentalomas

25 Apr, 2023 | 14:14h | UTC

Management of pituitary incidentalomas – Clinical Medicine Journal

 


Brief Review | Investigation and assessment of adrenal incidentalomas

25 Apr, 2023 | 14:13h | UTC

Investigation and assessment of adrenal incidentalomas – Clinical Medicine Journal

 


Brief Review | Thyroid disease in pregnancy

25 Apr, 2023 | 14:15h | UTC

Thyroid disease in pregnancy – Clinical Medicine Journal

 


RCT | Bariatric–metabolic surgery is more effective than lifestyle intervention plus best medical care in non-alcoholic steatohepatitis

24 Apr, 2023 | 14:03h | UTC

Bariatric–metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial – The Lancet

News Release: Surgery most effective treatment of metabolic liver disease – King’s College London

 

Commentary on Twitter

 


RCT | Intermittent fasting plus early time-restricted eating vs. calorie restriction and standard care in adults at risk of type 2 DM

24 Apr, 2023 | 13:07h | UTC

Intermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial – Nature Medicine (if the link is paywalled, try this one)

News Release: Fasting diet reduces risk markers of type 2 diabetes – University of Adelaide

Related:

RCT | Time-restricted eating not more effective than daily calorie restriction for managing nonalcoholic fatty liver disease

Health effects of the time-restricted eating in adults with obesity: A systematic review and meta-analysis – Frontiers in Nutrition

Time-restricted eating and exercise training improve HbA1c and body composition in women with overweight/obesity: A randomized controlled trial – Cell Metabolism

Effectiveness of Early Time-Restricted Eating for Weight Loss, Fat Loss, and Cardiometabolic Health in Adults With Obesity: A Randomized Clinical Trial – JAMA Internal Medicine

Effects of Intermittent Fasting in Human Compared to a Non-intervention Diet and Caloric Restriction: A Meta-Analysis of Randomized Controlled Trials – Frontiers in Nutrition

Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition

Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine

Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open

 

Commentary on Twitter

 


Study estimates poor diet causes 70% of diabetes cases globally

21 Apr, 2023 | 13:06h | UTC

Incident type 2 diabetes attributable to suboptimal diet in 184 countries – Nature Medicine

News Release: Study links poor diet to 14 million cases of type 2 diabetes globally – Tufts University

 

Commentary on Twitter

 


M-A | Adverse events related to tirzepatide (a dual GIP/GLP-1 receptor agonist)

21 Apr, 2023 | 12:59h | UTC

Adverse Events Related to Tirzepatide – Journal of the Endocrine Society

Related:

RCT | Safety and efficacy of Tirzepatide as an add-on to single oral antihyperglycaemic medication in patients with type 2 diabetes in Japan.

Tirzepatide Once Weekly for the Treatment of Obesity – New England Journal of Medicine

Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis – Diabetologia

Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis – Nature Medicine

Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

 


Study shows that parathyroidectomy in adults with primary hyperparathyroidism probably has no effect on kidney function

21 Apr, 2023 | 12:57h | UTC

Estimated Effect of Parathyroidectomy on Long-Term Kidney Function in Adults With Primary Hyperparathyroidism – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Study: Parathyroidectomy shows no effect on kidney function in older adults with hyperparathyroidism – American College of Physicians

Commentary: Parathyroidectomy for primary hyperparathyroidism didn’t affect kidney function in older patients – ACP Internist

 

Commentary on Twitter

 


Cluster RCT | Salt substitute outperforms salt restriction in lowering blood pressure in older patients

18 Apr, 2023 | 13:30h | UTC

Salt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial – Nature Medicine (if the link is paywalled, try this one)

Commentary: Exploring effectiveness of salt substitutes in elderly care facilities – Medical Xpress

Related:

Salt substitutes vs. regular salt: a quick look.

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

#ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Commentary on Twitter

 


Review | Current practice in the perioperative management of patients with diabetes mellitus

18 Apr, 2023 | 13:19h | UTC

Current practice in the perioperative management of patients with diabetes mellitus: a narrative review – British Journal of Anaesthesia

Related:

Guideline Summary: New guidance on the perioperative management of diabetes.

Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings

Recent advances in diabetes treatments and their perioperative implications – Current Opinion in Anesthesiology

Perioperative Management of Oral Glucose-lowering Drugs in the Patient with Type 2 Diabetes – Anesthesiology

 


M-A | Positive end-expiratory pressure and postoperative complications in patients with obesity

18 Apr, 2023 | 13:11h | UTC

Positive end-expiratory pressure and postoperative complications in patients with obesity: a review and meta-analysis – Obesity

 


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