Endocrinology (all articles)
Study shows that parathyroidectomy in adults with primary hyperparathyroidism probably has no effect on kidney function
21 Apr, 2023 | 12:57h | UTCEstimated Effect of Parathyroidectomy on Long-Term Kidney Function in Adults With Primary Hyperparathyroidism – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
New: #parathyroidectomy had no effect on long term #KidneyFunction in older adults w/ primary #hyperparathyroidism, but may preserve function in patients under 60. https://t.co/B456rPwGem pic.twitter.com/V8hLmrYiUX
— Annals of Int Med (@AnnalsofIM) April 17, 2023
Cluster RCT | Salt substitute outperforms salt restriction in lowering blood pressure in older patients
18 Apr, 2023 | 13:30h | UTCSalt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial – Nature Medicine (if the link is paywalled, try this one)
Commentary: Exploring effectiveness of salt substitutes in elderly care facilities – Medical Xpress
Related:
Salt substitutes vs. regular salt: a quick look.
Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
Commentary on Twitter
In a cluster-randomized trial in 48 residential elderly care facilities in China, a low-sodium salt substitute instead of regular salt decreased blood pressure and cardiovascular events, while restricting salt consumption did not show beneficial effects https://t.co/Zp0fWH0aA2
— Nature Medicine (@NatureMedicine) April 13, 2023
Review | Current practice in the perioperative management of patients with diabetes mellitus
18 Apr, 2023 | 13:19h | UTCRelated:
Guideline Summary: New guidance on the perioperative management of diabetes.
Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings
M-A | Positive end-expiratory pressure and postoperative complications in patients with obesity
18 Apr, 2023 | 13:11h | UTC
Report | The implications of defining obesity as a disease
18 Apr, 2023 | 12:55h | UTC
Commentary on Twitter
The implications of defining #obesity as a disease: a report from the ASO 2021 annual conference
"the goal is common: to provide a healthcare system that supports and protects the patients…and policies that reduce stigma and promote health equity"https://t.co/Iftxra5i2g pic.twitter.com/8luPJchn3x
— eClinicalMedicine – The Lancet Discovery Science (@eClinicalMed) April 11, 2023
RCT | Safety of Fezolinetant for vasomotor symptoms associated with menopause
17 Apr, 2023 | 12:54h | UTCRelated:
RCT | Fezolinetant for treatment of moderate-to-severe vasomotor symptoms associated with menopause
RCT | Efficacy of Fezolinetant in moderate-to-severe vasomotor symptoms associated with menopause
SR | Blood pressure control for diabetic retinopathy
17 Apr, 2023 | 12:45h | UTCBlood pressure control for diabetic retinopathy – Cochrane Library
Summary: Blood pressure control for diabetic retinopathy – Cochrane Library
Review | Diagnosis and management of prediabetes
12 Apr, 2023 | 13:28h | UTCDiagnosis and Management of Prediabetes: A Review – JAMA (free for a limited period)
Editorial: Prediabetes Diagnosis and Management – JAMA (free for a limited period)
Video: Screening for Prediabetes – JAMA
Audio Clinical Review: Diagnosis and Management of Patients With Prediabetes – JAMA
Single arm trial | Safety of metformin continuation in diabetic patients undergoing invasive coronary angiography
12 Apr, 2023 | 13:06h | UTC
M-A | The risk of long-term cardiometabolic disease in women with premature or early menopause
11 Apr, 2023 | 13:59h | UTC
M-A | Benefits and harms of drug treatment for type 2 diabetes
10 Apr, 2023 | 14:03h | UTC
Umbrella review unveils benefits of cutting free sugars to 6 teaspoons/day
10 Apr, 2023 | 14:00h | UTCDietary sugar consumption and health: umbrella review – The BMJ
News Release: Limit added sugar to six teaspoons a day to improve health, urge experts – BMJ Newsroom
Swiss recommendations for the treatment of type 2 diabetes mellitus
10 Apr, 2023 | 13:50h | UTCRelated: Guideline | ADA 2023 Standards of Medical Care in Diabetes.
Cohort Study | Pregnancy glucose intolerance, even below diabetes criteria, linked to increased risk of type 2 diabetes
5 Apr, 2023 | 13:42h | UTCGlucose intolerance in pregnancy and risk of early-onset type 2 diabetes: a population-based cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Pharmacotherapy of obesity: an update on the available medications and drugs under investigation
5 Apr, 2023 | 12:50h | UTC
M-A | Efficacy of flash glucose monitoring in type 1 and type 2 diabetes
5 Apr, 2023 | 12:46h | UTC
RCT | No significant fracture reduction from monthly 60,000 IU vitamin D3 supplementation
4 Apr, 2023 | 13:58h | UTCThe effect of monthly vitamin D supplementation on fractures: a tertiary outcome from the population-based, double-blind, randomised, placebo-controlled D-Health trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Related:
RCT | Supplemental Vitamin D does not reduce incident fractures in midlife and older adults.
RCT | Vitamin D supplementation shows no significant impact on psoriasis severity
4 Apr, 2023 | 13:51h | UTCSummary: In a randomized, double-blind, placebo-controlled clinical trial involving 122 participants with plaque psoriasis, researchers investigated the effects of vitamin D supplementation on psoriasis severity during winter. Participants received either vitamin D (cholecalciferol, 100,000 IU loading dose followed by 20,000 IU/week) or a placebo for four months. The primary outcome was Psoriasis Area Severity Index (PASI) scores, with secondary outcomes including Physician Global Assessment, self-administered PASI, and Dermatology Life Quality Index scores.
The study found no significant difference in PASI scores or secondary outcomes between the two groups. The results suggest that vitamin D supplementation does not affect psoriasis severity. However, low baseline severity scores and a lower than expected increase in 25-hydroxyvitamin D levels in the intervention group may have influenced the findings, indicating that further research may be needed to account for these factors.
Article: Effect of Vitamin D Supplementation on Psoriasis Severity in Patients With Lower-Range Serum 25-Hydroxyvitamin D Levels: A Randomized Clinical Trial – JAMA Dermatology (free for a limited period)
Commentary on Twitter
This RCT, performed in North-Norway, found no measurable effect of vitamin D supplementation on psoriasis severity during winter. Low baseline severity, & lower-than-expected rise in 25(OH)D levels in intervention group, may have affected the results. https://t.co/ip17uFQsgM
— JAMA Dermatology (@JAMADerm) March 29, 2023
Cohort Study | Preoperative depression has minimal impact on 5-year bariatric surgery outcomes
4 Apr, 2023 | 13:23h | UTC
Single-arm study | Transcatheter arterialization of deep veins may help avoid amputation in chronic limb-threatening ischemia
3 Apr, 2023 | 14:03h | UTCTranscatheter Arterialization of Deep Veins in Chronic Limb-Threatening Ischemia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
New procedure helps patients avoid leg amputation – Vanderbilt University
PROMISE II: Flow-Diverting Procedure May Save Limbs in CLTI – TCTMD
Transcatheter Arterialization Could Revolutionize Treatment of Limb-Threatening Ischemia – HCP Live
Transcatheter Arterialization for Limb Ischemia – American College of Cardiology
Commentary on Twitter
Transcatheter arterialization of deep veins resulted in 6-month amputation-free survival in 66.1% of 105 patients with chronic limb-threatening ischemia and no conventional options for treatment. Full results of PROMISE II study: https://t.co/OJK0xmpwPF#cardiology pic.twitter.com/OrhP7YFu8u
— NEJM (@NEJM) March 29, 2023
M-A | Mediterranean & low-fat diets may reduce mortality and non-fatal MI in patients with high cardiovascular risk
3 Apr, 2023 | 13:59h | UTCSummary: This systematic review and network meta-analysis aimed to determine the relative efficacy of different diets for preventing mortality and major cardiovascular events in patients at increased risk of cardiovascular disease. The study identified 40 randomized trials with 35,548 participants across seven dietary programs.
Moderate certainty evidence showed that Mediterranean and low-fat diets, with or without physical activity or other interventions, reduced all-cause mortality and non-fatal myocardial infarction in patients with increased cardiovascular risk. Mediterranean diet programs were also likely to reduce stroke risk.
Other dietary programs generally were not superior to minimal intervention. When compared with one another, no convincing evidence was found that the Mediterranean diet was superior to the low-fat diets in preventing mortality or non-fatal myocardial infarction.
News Release: Benefits of Mediterranean and low fat diet programmes in patients at risk of cardiovascular disease – BMJ Newsroom
Commentary: Mediterranean, Low-Fat Diets Both Good for Health: Network Meta-analysis – TCTMD
Assessment of childhood short stature: a GP guide
3 Apr, 2023 | 13:28h | UTCAssessment of childhood short stature: a GP guide – British Journal of General Practice (free for a limited period)
Assessing heart failure risk: waist-to-height ratio outperforms BMI in HFrEF patients
31 Mar, 2023 | 13:49h | UTCCommentary: Study Debunks Obesity Paradox in HF, Encourages BMI Alternatives – TCTMD
M-A | Effects of statin therapy on glycemic control and insulin resistance
31 Mar, 2023 | 13:45h | UTCRelated:
Cohort study: Statin therapy initiation linked to increased risk of diabetes progression.
Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes
Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins
Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes
Review | Management of immune related endocrinopathies following immune checkpoint inhibitor therapy for cancer
31 Mar, 2023 | 13:23h | UTCRelated: