Endocrinology (all articles) | Page 18 of 89 | Links Medicus Content Curation & Alerts in Medicine

#ESCCongress – RCT | A large study with 46.611 individuals between 65 and 74 years of age found that a comprehensive cardiovascular screening program did not significantly reduce the incidence of death from any cause.

29 Aug, 2022 | 12:24h | UTC

Five-Year Outcomes of the Danish Cardiovascular Screening (DANCAVAS) Trial – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Cardiovascular screening may reduce risk of death and cardiovascular disease – European Society of Cardiology

Commentary on Twitter

DANCANVAS: In men age 65-74 years in Denmark, those randomized to invitation to comprehensive screening for subclinical CVD did not have signif reduced all-cause mortality at median 5.6 yrs of follow-up. #ESCCongress https://t.co/YZL87aTVHR pic.twitter.com/HfdiNuU9sK

— NEJM (@NEJM) August 27, 2022

[News release – not published yet] #ESCCongress – RCT | Allopurinol does not improve cardiovascular outcomes in ischemic heart disease patients.

29 Aug, 2022 | 12:15h | UTC

Allopurinol does not improve cardiovascular outcomes in ischaemic heart disease patients – European Society of Cardiology

Commentary:

ALL-HEART: Gout Drug Allopurinol No Help in CV Prevention – TCTMD

No improvement with allopurinol for patients with ischemic heart disease: ALL-HEART – Cardiology Now

Update on the management of diabetes in long-term care facilities.

26 Aug, 2022 | 13:23h | UTC

Update on the management of diabetes in long-term care facilities – BMJ Open Diabetes Research & Care

Randomized Crossover Trial | In patients with diabetic neuropathic pain, amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin were similarly effective.

25 Aug, 2022 | 12:14h | UTC

Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial – The Lancet

Study Commentary | Is the evidence strong for spinal cord stimulation for diabetic neuropathy? Not all experts agree.

25 Aug, 2022 | 11:52h | UTC

Is the Evidence Strong for Spinal Cord Stimulation for Diabetic Neuropathy? Not All Experts Agree – Neurology Today

Original Study: RCT: Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy

USPSTF Recommendation Statement | Statin use for the primary prevention of cardiovascular disease in adults.

24 Aug, 2022 | 14:21h | UTC

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement – JAMA

Editorials:

Statins for Primary Cardiovascular Disease Prevention: Time to Curb Our Enthusiasm – JAMA Internal Medicine

Statins and Primary Atherosclerotic Cardiovascular Disease Prevention—What We Know, Where We Need to Go, and Why Are We Not There Already? – JAMA Network Open

Evidence Report: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author Interview: USPSTF Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults – JAMA

Patient Page: Statins for the Prevention of Cardiovascular Disease – JAMA

Commentary: Latest statins guidance keeps more conservative approach to preventing first stroke or heart attack – CNN

Non-nutritive sweeteners affect human microbiomes and can alter glycemic responses.

24 Aug, 2022 | 14:17h | UTC

News Release: Non-nutritive sweeteners affect human microbiomes and can alter glycemic responses – Cell Press

Original Study: Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance – Cell

Commentary: Expert reaction to study looking at the effect of non-nutritive sweeteners on human microbiomes and glycaemic levels – Science Media Centre

Commentary on Twitter

The skinny on non-nutritive sweeteners (they are not inert) via a randomized trial & gut #microbiome assessment: impact is individualized and can impair glycemic responsehttps://t.co/B7CUPy7tMf @CellCellPress @SuezLab @EranElinav @segal_eran @WeizmannScience @Yot_Coh @Elinav_Lab pic.twitter.com/Jz7lUkWlNr

— Eric Topol (@EricTopol) August 19, 2022

Podcast | USPSTF Update: aspirin for primary prevention of cardiovascular disease.

24 Aug, 2022 | 14:05h | UTC

#347 USPSTF Update: Aspirin for Primary Prevention of CVD – The Curbsiders

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

Guideline | Management of adults with diabetes on dialysis.

23 Aug, 2022 | 13:16h | UTC

Management of adults with diabetes on dialysis – Joint British Diabetes Societies for Inpatient Care (PDF)

News Release: Latest JBDS dialysis guideline published – Diabetes Times

RCT | Effectiveness of an intervention for reducing sitting time and improving health in office workers.

22 Aug, 2022 | 12:19h | UTC

Effectiveness of an intervention for reducing sitting time and improving health in office workers: three arm cluster randomised controlled trial – The BMJ

Editorial: The importance of sitting less and moving more – The BMJ

News Release: Standing desks alongside other measures cut office workers’ sitting time by an hour a day – BMJ Newsroom

Commentary: SMART Work and Life Intervention Reduces Sitting Time for Office Workers – HealthDay

Commentary on Twitter

Using a standing desk alongside a package of other measures to encourage office workers to sit less and move more, reduced sitting time by about an hour a day over one year, finds a trial published in @bmj_latest today https://t.co/uxaDWnp5WB

— The BMJ (@bmj_latest) August 18, 2022

Guideline | Management of eating disorders for people with higher weight.

22 Aug, 2022 | 12:11h | UTC

Management of eating disorders for people with higher weight: clinical practice guideline – Journal of Eating Disorders

Review | Treatments targeting neuroendocrine dysfunction in polycystic ovary syndrome.

22 Aug, 2022 | 11:59h | UTC

Treatments targeting neuroendocrine dysfunction in polycystic ovary syndrome (PCOS) – Clinical Endocrinology

RCT | A lower glycemic criteria in not better than higher glycemic criteria for the diagnosis of gestational diabetes.

18 Aug, 2022 | 13:04h | UTC

Lower versus Higher Glycemic Criteria for Diagnosis of Gestational Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Pros and cons with lower vs higher threshold for gestational diabetes diagnosis – medwire News

Commentary on Twitter (thread – click for more)

1/ Overdiagnosis of Gestational Diabetes (GDM): New large randomized trial compared broader/narrower criteria -> NO improvement in mother/baby outcomes BUT x2 increase in % pregnant women labelled as GDM. Time to reconsider GDM testing – https://t.co/xrr0XrdhaZ

— Paul Glasziou (@PaulGlasziou) August 18, 2022

Executive Summary | Guidelines for adrenalectomy.

18 Aug, 2022 | 12:58h | UTC

American Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary – JAMA Surgery (free for a limited period)

Author interview: American Association of Endocrine Surgeons Guidelines for Adrenalectomy – JAMA

M-A | Performance of confirmatory tests for diagnosing primary aldosteronism.

18 Aug, 2022 | 12:54h | UTC

Performance of Confirmatory Tests for Diagnosing Primary Aldosteronism: a Systematic Review and Meta-Analysis – Hypertension

Commentary on Twitter

Less than 1% of patients suffering from PA are treated. Current strategies for diagnosing PA don't work well. Simplify testing for better diagnosis and treatment #hypertension #PrimaryAldosteronism @dr_alexleung @JanicePasieka @IAESurgeons https://t.co/AKkyUfSLoG pic.twitter.com/HcLQTdB2ao

— Hypertension (@HyperAHA) August 16, 2022

Perspective | Is there an optimal diet for primordial prevention of atherosclerosis?

17 Aug, 2022 | 14:23h | UTC

Is there an optimal diet for primordial prevention of atherosclerosis? – European Journal of Cardiology

Pre-post study | Junk food advertising restrictions linked to reductions in high fat, salt and sugar product purchases.

17 Aug, 2022 | 14:21h | UTC

Changes in household food and drink purchases following restrictions on the advertisement of high fat, salt, and sugar products across the Transport for London network: A controlled interrupted time series analysis – PLOS Medicine

News Release: Transport for London’s junk food advertising restrictions linked to reductions in high fat, salt and sugar product purchases – London School of Hygiene & Tropical Medicine

Commentaries:

Advertising ban was linked to lower purchases of unhealthy food and drink – National Institute for Health and Care Research

TfL junk food advert ban: Has the policy cut obesity? – BBC

Commentary from the author on Twitter (thread – click for more)

In our exciting new paper ? published today in @PLOSMedicine we find the @MayorofLondon @TfL ban on #junkfood advertising reduces average household purchases of energy from HFSS grocery products by 1,001 kcal per week ?1/12 https://t.co/pRh0BlkKJU

— Steven Cummins (@stevencjcummins) February 17, 2022