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Endocrinology (all articles)

Cohort Study | Associations of hypertriglyceridemia onset age with cardiovascular disease and all‐cause mortality in adults.

20 Oct, 2022 | 12:25h | UTC

Associations of Hypertriglyceridemia Onset Age With Cardiovascular Disease and All‐Cause Mortality in Adults: A Cohort Study – Journal of the American Heart Association

 


Cross-sectional study | Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease.

20 Oct, 2022 | 12:22h | UTC

Lipoprotein(a) levels in a global population with established atherosclerotic cardiovascular disease – openheart

 

Commentary on Twitter

Under a http://creativecommons.org/licenses/by-nc/4.0/ license

 


RCT | Combination of pitavastatin and ezetimibe vs. monotherapy of pitavastatin in patients with primary hypercholesterolemia.

19 Oct, 2022 | 14:15h | UTC

A Multicenter, Randomized, Double-Blind, Active-Controlled, Factorial Design, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of Pitavastatin and Ezetimibe Versus Monotherapy of Pitavastatin in Patients With Primary Hypercholesterolemia – Clinical Therapeutics

 


M-A | Safety of sotagliflozin in diabetes mellitus type 1 and type 2.

19 Oct, 2022 | 14:12h | UTC

The safety of sotagliflozin in the therapy of diabetes mellitus type 1 and type 2: A meta-analysis of randomized trials – Frontiers in Endocrinology

 


M-A | Cardiovascular and renal efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients without diabetes.

19 Oct, 2022 | 14:11h | UTC

Cardiovascular and renal efficacy and safety of sodium-glucose cotransporter-2 inhibitors in patients without diabetes: a systematic review and meta-analysis of randomised placebo-controlled trials – BMJ Open

 


Retrospective Cohort Study | Trends in the association between diabetes and cardiovascular events, 1994-2019.

18 Oct, 2022 | 12:58h | UTC

Trends in the Association Between Diabetes and Cardiovascular Events, 1994-2019 – JAMA (free for a limited period)

Related Study: Study shows that the leading causes of hospitalization of adults with diabetes are changing.

 


RCT | Two-year effects of Semaglutide in adults with overweight or obesity.

18 Oct, 2022 | 12:53h | UTC

Two-year effects of semaglutide in adults with overweight or obesity: the STEP 5 trial – Nature Medicine

Commentary: STEP 5: Sustained semaglutide treatment maintains weight loss – medwire News

Related:

RCT: Effect of continued weekly subcutaneous Semaglutide vs. placebo on weight loss maintenance in adults with overweight or obesity

RCT: High dose once a week Semaglutide (2.4 mg) in adults with overweight or obesity, and type 2 diabetes

RCT: Effect of high-dose subcutaneous Semaglutide vs. placebo in adults with overweight or obesity

RCT: Once-weekly, high-dose semaglutide is effective for improving overweight or obesity among non-diabetic adults

 

Commentary on Twitter

 


Perspective | The polypill: from concept and evidence to implementation.

18 Oct, 2022 | 12:55h | UTC

The polypill: from concept and evidence to implementation – The Lancet (free registration required)

News Release: The polypill could avoid millions of premature deaths, heart attacks and strokes every year, say leading cardiology experts – McMaster University

Related:

#ESCCongress | In patients within 6 months of a myocardial infarction, a polypill containing aspirin, ramipril, and atorvastatin resulted in a lower risk of major adverse cardiovascular events compared to usual care.

#ESCCongress – M-A: Polypills with and without aspirin substantially reduce cardiovascular disease, myocardial infarction, stroke, revascularization, and cardiovascular death in primary cardiovascular disease prevention.

Opinion: A new important study supports wider use of the polypill

#AHA20 – Randomized trial: A polypill comprising statins, multiple blood pressure lowering drugs, and aspirin prevents cardiovascular events among patients at intermediate cardiovascular risk

Perspective: Are Polypills and Population-based Treatment the Next Big Things?

The Polypill Revisited: Why We Still Need Population-Based Approaches in the Precision Medicine Era

Randomized Trial: Polypill for Cardiovascular Disease Prevention in an Underserved Population

Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases

Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart

Perspective: The Polypill and the Long Journey to Major Impact

Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care

 


Position Statement | Changing the name of diabetes insipidus.

18 Oct, 2022 | 12:50h | UTC

Changing the name of diabetes insipidus: a position statement of The Working Group for Renaming Diabetes Insipidus – Endocrine Connections

 


M-A | Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome.

18 Oct, 2022 | 12:37h | UTC

Impact of metformin on the clinical and metabolic parameters of women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trials – Therapeutic Advances in Endocrinology and Metabolism

 


Cluster RCT | Culturally sensitive vs. standard behavioral approach for promoting weight-loss maintenance in black women.

14 Oct, 2022 | 14:04h | UTC

Promoting weight-loss maintenance among Black women primary care patients: A cluster RCT of a culturally sensitive versus standard behavioural approach – Clinical Obesity

 


Cohort Study | Duration of diabetes and use of insulin are the most important predictors of diabetic retinopathy.

13 Oct, 2022 | 13:44h | UTC

Presence and development of diabetic retinopathy in 153 238 patients with type 2 diabetes in the Danish Registry of Diabetic Retinopathy – Acta Ophthalmologica

Commentary: Insulin Use May Predict the Development of Diabetic Retinopathy – HCP Live

 


Systematic Review | Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency.

13 Oct, 2022 | 13:39h | UTC

Hormone therapy for uterine and endometrial development in women with premature ovarian insufficiency – Cochrane Library

Summary: Which hormonal therapy works better for women with early failure of the ovaries? – Cochrane Library

 

Commentary on Twitter

 


Cohort Study | Effect of diabetes on morbidity and mortality in patients with acromegaly.

13 Oct, 2022 | 13:37h | UTC

Effect of Diabetes on Morbidity and Mortality in Patients With Acromegaly – The Journal of Clinical Endocrinology & Metabolism

 

Commentary on Twitter

 


Calculator | Estimating individual lifetime risk of cardiovascular events in adults with type 2 diabetes.

11 Oct, 2022 | 13:29h | UTC

Estimating individual lifetime risk of incident cardiovascular events in adults with type 2 diabetes: an update and geographical calibration of the DIAbetes Lifetime perspective model (DIAL2) – European Journal of Preventive Cardiology

See also: DIAL Model Calculator

 


Diabetic kidney disease back in focus: management field guide for health care professionals in the 21st century.

7 Oct, 2022 | 14:08h | UTC

Diabetic Kidney Disease Back in Focus: Management Field Guide for Health Care Professionals in the 21st Century – Mayo Clinic Proceedings

Related: ADA/KDIGO Consensus Report | Diabetes management in chronic kidney disease.

 


EASD/ADA Consensus Report | Automated insulin delivery: benefits, challenges, and recommendations.

6 Oct, 2022 | 13:46h | UTC

Automated insulin delivery: benefits, challenges, and recommendations. A Consensus Report of the Joint Diabetes Technology Working Group of the European Association for the Study of Diabetes and the American Diabetes Association – Diabetologia (if the link is paywalled, try this one)

Related: Consensus Recommendations for the Use of Automated Insulin Delivery (AID) Technologies in Clinical Practice – Endocrine Reviews

 


Systematic Review | There is little evidence on pharmacological interventions to prevent weight gain in people with schizophrenia.

6 Oct, 2022 | 13:39h | UTC

Pharmacological interventions for prevention of weight gain in people with schizophrenia – Cochrane Library

Summary: How effective are medications given alongside antipsychotics at preventing weight gain in people with schizophrenia? – Cochrane Library

 


ADA/KDIGO Consensus Report | Diabetes management in chronic kidney disease.

5 Oct, 2022 | 13:59h | UTC

Diabetes Management in Chronic Kidney Disease: A Consensus Report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO) – Kidney International

News Release: NEWS RELEASE: ADA & KDIGO Release Joint Consensus Report on Diabetes Management in CKD

 


Expert consensus | Glycemic management of critically ill patients.

4 Oct, 2022 | 14:38h | UTC

Expert consensus on the glycemic management of critically ill patients – Journal of Intensive Medicine

Related: Review | Glycemic control in the critically ill: Less is more.

 


Cohort Study | Diabetes diagnosed at younger ages is associated with increased morbidity compared to diagnosis in older adults.

3 Oct, 2022 | 14:02h | UTC

Associations of Age at Diagnosis and Duration of Diabetes With Morbidity and Mortality Among Older Adults – JAMA Network Open

 


Guideline | Operative management of acute abdomen after bariatric surgery in the emergency setting.

3 Oct, 2022 | 13:59h | UTC

Operative management of acute abdomen after bariatric surgery in the emergency setting: the OBA guidelines – World Journal of Emergency Surgery

Related: AGA clinical practice update on evaluation and management of early complications after bariatric/metabolic surgery.

 


RCT | Doxycycline vs. placebo in patients with mild thyroid-associated ophthalmopathy.

30 Sep, 2022 | 12:35h | UTC

Doxycycline vs Placebo at 12 Weeks in Patients With Mild Thyroid-Associated Ophthalmopathy: A Randomized Clinical Trial – JAMA Ophthalmology (free for a limited period)

Invited commentary: Oral Doxycycline for Mild Thyroid Eye Disease – JAMA Opthalmology (free for a limited period)

 


RCT | In patients with Type 1 Diabetes, the use of a “bionic pancreas” reduced HbA1c without increasing hypoglycemia.

29 Sep, 2022 | 13:35h | UTC

Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Bionic pancreas improves type 1 diabetes management compared to standard insulin delivery methods – National Institutes of Health

 


Cohort Study | Association between dairy intake and risk of CV disease and mortality in patients with stable angina pectoris.

28 Sep, 2022 | 13:38h | UTC

The association between dairy intake and risk of cardiovascular disease and mortality in patients with stable angina pectoris – European Journal of Preventive Cardiology

 


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