Diabetes
Evidence-based recommendations for the dietary management of diabetes
8 May, 2023 | 12:56h | UTCEvidence-based European recommendations for the dietary management of diabetes – Diabetologia (if the link is paywalled, try this one)
SR | In people with prediabetes, Vitamin D may have a small benefit in decreasing the risk of diabetes
4 May, 2023 | 13:28h | UTCVitamin D and Risk for Type 2 Diabetes in People With Prediabetes: A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
How Helpful Is Vitamin D in Prediabetes? – ConscienHealth
RCT | Best endovascular treatment first strategy yields better outcomes for chronic limb ischemia vs. vein bypass first strategy
3 May, 2023 | 15:39h | UTCCommentary: BASIL-2 Supports Endo-First Strategy for CLTI With Infrapopliteal Disease – TCTMD
RCT | Intermittent fasting plus early time-restricted eating vs. calorie restriction and standard care in adults at risk of type 2 DM
24 Apr, 2023 | 13:07h | UTCIntermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial – Nature Medicine (if the link is paywalled, try this one)
News Release: Fasting diet reduces risk markers of type 2 diabetes – University of Adelaide
Related:
Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition
Commentary on Twitter
A study in @NatureMedicine comparing intermittent fasting plus early time-restricted eating (iTRE) to calorie restriction in adults at risk of type 2 diabetes shows that iTRE was associated with greater improvements in postprandial glucose metabolism. ? https://t.co/NsMn5xLvmE pic.twitter.com/gNbfGORhby
— Nature Portfolio (@NaturePortfolio) April 19, 2023
Study estimates poor diet causes 70% of diabetes cases globally
21 Apr, 2023 | 13:06h | UTCIncident type 2 diabetes attributable to suboptimal diet in 184 countries – Nature Medicine
News Release: Study links poor diet to 14 million cases of type 2 diabetes globally – Tufts University
Commentary on Twitter
An analysis in @NatureMedicine estimates that 70% of new global cases of type 2 diabetes are attributable to suboptimal intake of 11 dietary factors, with substantial differences in dietary risks across world regions and nations. https://t.co/MYoLRt3rhO pic.twitter.com/Pv7I6Mhvxu
— Nature Portfolio (@NaturePortfolio) April 19, 2023
M-A | Adverse events related to tirzepatide (a dual GIP/GLP-1 receptor agonist)
21 Apr, 2023 | 12:59h | UTCAdverse Events Related to Tirzepatide – Journal of the Endocrine Society
Related:
Tirzepatide Once Weekly for the Treatment of Obesity – New England Journal of Medicine
Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis – Nature Medicine
Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Review | Current practice in the perioperative management of patients with diabetes mellitus
18 Apr, 2023 | 13:19h | UTCRelated:
Guideline Summary: New guidance on the perioperative management of diabetes.
Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings
Review | Diagnosis and management of prediabetes
12 Apr, 2023 | 13:28h | UTCDiagnosis and Management of Prediabetes: A Review – JAMA (free for a limited period)
Editorial: Prediabetes Diagnosis and Management – JAMA (free for a limited period)
Video: Screening for Prediabetes – JAMA
Audio Clinical Review: Diagnosis and Management of Patients With Prediabetes – JAMA
Single arm trial | Safety of metformin continuation in diabetic patients undergoing invasive coronary angiography
12 Apr, 2023 | 13:06h | UTC
M-A | Benefits and harms of drug treatment for type 2 diabetes
10 Apr, 2023 | 14:03h | UTC
Swiss recommendations for the treatment of type 2 diabetes mellitus
10 Apr, 2023 | 13:50h | UTCRelated: Guideline | ADA 2023 Standards of Medical Care in Diabetes.
Cohort Study | Pregnancy glucose intolerance, even below diabetes criteria, linked to increased risk of type 2 diabetes
5 Apr, 2023 | 13:42h | UTCGlucose intolerance in pregnancy and risk of early-onset type 2 diabetes: a population-based cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
M-A | Efficacy of flash glucose monitoring in type 1 and type 2 diabetes
5 Apr, 2023 | 12:46h | UTC
Single-arm study | Transcatheter arterialization of deep veins may help avoid amputation in chronic limb-threatening ischemia
3 Apr, 2023 | 14:03h | UTCTranscatheter Arterialization of Deep Veins in Chronic Limb-Threatening Ischemia – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
New procedure helps patients avoid leg amputation – Vanderbilt University
PROMISE II: Flow-Diverting Procedure May Save Limbs in CLTI – TCTMD
Transcatheter Arterialization Could Revolutionize Treatment of Limb-Threatening Ischemia – HCP Live
Transcatheter Arterialization for Limb Ischemia – American College of Cardiology
Commentary on Twitter
Transcatheter arterialization of deep veins resulted in 6-month amputation-free survival in 66.1% of 105 patients with chronic limb-threatening ischemia and no conventional options for treatment. Full results of PROMISE II study: https://t.co/OJK0xmpwPF#cardiology pic.twitter.com/OrhP7YFu8u
— NEJM (@NEJM) March 29, 2023
M-A | Effects of statin therapy on glycemic control and insulin resistance
31 Mar, 2023 | 13:45h | UTCRelated:
Cohort study: Statin therapy initiation linked to increased risk of diabetes progression.
Meta-Analysis: Medications that Reduce or Increase the Risk of New Onset Diabetes
Observational Study Points to an Increased Risk of Diabetes Among Patients Using Statins
Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes
Phase 2 RCT | Safety and efficacy of once-weekly basal insulin Fc in people with type 2 diabetes
30 Mar, 2023 | 14:08h | UTCSafety and efficacy of once-weekly basal insulin Fc in people with type 2 diabetes previously treated with basal insulin: a multicentre, open-label, randomised, phase 2 study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
SR | Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy
29 Mar, 2023 | 13:15h | UTCAnti‐vascular endothelial growth factor for proliferative diabetic retinopathy – Cochrane Library
Podcast | Diabetes updates
29 Mar, 2023 | 13:09h | UTC#387: Diabetes Updates with Dr. Marie McDonnell: New Tools for the New Rules – The Curbsiders
A syndrome-specific antibiotic stewardship intervention reduced antipseudomonal antibiotic use in diabetic foot infections
29 Mar, 2023 | 13:10h | UTC
Practical guide to glucocorticoid induced hyperglycemia and diabetes
28 Mar, 2023 | 14:35h | UTCPractical Guide to Glucocorticoid Induced Hyperglycaemia and Diabetes – Diabetes Therapy
Exploratory analysis | Hypoglycemia incidence is lower with linagliptin vs. glimepiride in patients with early type 2 DM
22 Mar, 2023 | 13:15h | UTC
RCT | Closed-loop insulin delivery system enhances blood sugar control in young children with type 1 diabetes
20 Mar, 2023 | 13:54h | UTCSummary: The study enrolled 102 young children between ages 2 and 5, randomized in a 2:1 ratio to either a closed-loop control system of insulin delivery (“artificial pancreas”) or a standard care comparison group. During the 13 weeks of study follow-up, participants in the artificial pancreas group spent 12% more time within their target blood glucose range compared to the standard care group.
The closed-loop group experienced two cases of severe hypoglycemia, while the standard-care group had one case. In the closed-loop group, one case of diabetic ketoacidosis occurred due to a problem with the insulin pump.
Article: Trial of Hybrid Closed-Loop Control in Young Children with Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
News Releases:
Commentary on Twitter
In children 2 to younger than 6 years of age with type 1 diabetes, a closed-loop control system was associated with a greater percentage of time in the target glycemic range than standard care. https://t.co/rAOLXRNuub#pediatrics #T1D pic.twitter.com/Nzwl3aFr1w
— NEJM (@NEJM) March 17, 2023
M-A | Global prevalence of diabetic retinopathy in pediatric type 2 diabetes
20 Mar, 2023 | 13:12h | UTC
Post-hoc analysis | Could SGLT2 inhibitors have a beneficial effect on gout symptoms?
17 Mar, 2023 | 13:02h | UTCRelated: Post-hoc analysis | Can SGLT2 inhibitors reduce the risk of hyperuricemia and gout?
RCT | Insulin degludec is noninferior to insulin detemir for the treatment of pregnant women with type 1 diabetes
16 Mar, 2023 | 12:59h | UTCInsulin degludec versus insulin detemir, both in combination with insulin aspart, in the treatment of pregnant women with type 1 diabetes (EXPECT): an open‑label, multinational, randomised, controlled, non-inferiority trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)