Editor's Choice
Top studies of 2021 relevant to primary care.
26 May, 2022 | 10:55h | UTCTop studies of 2021 relevant to primary care: From the PEER team – Canadian Family Physician
Study reports first use of antivirals in monkeypox patients.
26 May, 2022 | 11:27h | UTCNews Release: Study reports first use of antivirals in monkeypox patients – Lancet
Original Study: Clinical features and management of human monkeypox: a retrospective observational study in the UK – The Lancet Infectious Diseases
Commentary: Antiviral drug may limit monkeypox symptom duration, infectiousness – CIDRAP
Commentary from one of the author on Twitter (thread – click for more)
Clinical features and management of human monkeypox: a retrospective observational study in the UK https://t.co/0nUtw3lEDn
— Jake Dunning (@OutbreakJake) May 24, 2022
Cohort Study: Protection and waning of natural and hybrid immunity to SARS-CoV-2.
26 May, 2022 | 11:07h | UTCProtection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine
Editorial: Audio Interview: Waning Immunity against Covid-19
Commentary on Twitter
Protection against SARS-CoV-2 waned over time in both vaccinated and previously infected persons; an additional vaccine dose restored protection, find investigators from Israel. https://t.co/617uBmWu8l pic.twitter.com/yiDnBbCuQ5
— NEJM (@NEJM) May 25, 2022
Study Commentary: Long COVID risk falls only slightly after vaccination, huge study shows.
26 May, 2022 | 11:25h | UTCCommentary: Long COVID risk falls only slightly after vaccination, huge study shows – Nature
Original Study: Long COVID after breakthrough SARS-CoV-2 infection – Nature Medicine
Commentary from the author on Twitter (thread – click for more)
The latest from our team in @NatureMedicine
Does vaccination protect from #LongCovid?
Vaccines modestly reduce but do not eliminate risk of Long Covid @VAResearch @vahsrd @WUSTLmed @WUSTLnews @VREFSTL@Biostayan @BCBowe https://t.co/UEexmL8svS
A thread ?
— Ziyad Al-Aly, MD (@zalaly) May 25, 2022
Cohort Study: Trajectory of long covid symptoms after covid-19 vaccination.
26 May, 2022 | 11:23h | UTCTrajectory of long covid symptoms after covid-19 vaccination: community based cohort study – The BMJ
Editorial: Are vaccines a potential treatment for long covid? – The BMJ
News Release: Vaccination after SARS-CoV-2 infection linked to a decrease in long covid symptoms – BMJ Newsroom
Commentary on Twitter
LONG COVID: Number of well controlled studies (controls means comparison group of 1) unvaccinated and 2) those who have never had COVID) that show vaccination works to reduce or eliminate long COVID symptoms increasing. BMJ below + biggest from Israel herehttps://t.co/jtZ6aoDmFA https://t.co/n5oDs0Zxe9
— Monica Gandhi MD, MPH (@MonicaGandhi9) May 19, 2022
Test-negative, case–control study: effectiveness of homologous and heterologous Covid-19 boosters against Omicron.
26 May, 2022 | 10:59h | UTC
Navigating financial toxicity in patients with cancer: A multidisciplinary management approach.
26 May, 2022 | 10:57h | UTCRelated:
Not Just Nausea And Vomiting: Cancer Docs Now Worry About ‘Financial Toxicity’ – WBUR
Financial Toxicity and Cancer Treatment (PDQ®) – National Institute of Cancer
The Lancet Series: Urban design, transport, and health.
26 May, 2022 | 10:49h | UTCHomepage: Urban design, transport, and health – The Lancet Global Health
Series:
Commentaries:
Creating healthy and sustainable cities: what gets measured, gets done
Urban design is key to healthy environments for all
Measuring what matters: supporting cities in tackling climate and health challenges
The future is urban: integrated planning policies can enable healthy and sustainable cities
Commentary on Twitter
Delighted to announce the publication of our Series on urban design, transport, and health. Visit the hub page for the full Series, Comments, and added extras: https://t.co/dQrsK4jrGe pic.twitter.com/AAi9BeuRhy
— The Lancet Global Health (@LancetGH) May 11, 2022
Characterizing and quantifying low-value diagnostic imaging internationally: a scoping review.
26 May, 2022 | 10:48h | UTC
Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019.
25 May, 2022 | 11:51h | UTCNews Release: Worldwide shortage of health workers threatens effective health coverage – Institute for Health Metrics and Evaluation
Commentaries on Twitter
Considerable expansion of the world's health workforce is needed to reach targets for #UHC—new #GBDStudy estimates a shortage of 43 million health workers in 2019.
More: https://t.co/FknaY0Onzl @IHME_UW pic.twitter.com/sydiV2Ze1e
— The Lancet (@TheLancet) May 24, 2022
? IHME #GBDStudy reveals that more than 43 million additional health workers are needed globally and ensure all people worldwide have access to the health services they need. #HRH #UHC
Read study here »https://t.co/op3iTNZHtJ pic.twitter.com/LkU3V5tFFN— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) May 23, 2022
RCT: The addition of Metformin to standard therapy did not improve outcomes in patients with breast cancer.
25 May, 2022 | 11:49h | UTCEffect of Metformin vs Placebo on Invasive Disease–Free Survival in Patients With Breast Cancer: The MA.32 Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Who Will Benefit From Metformin? – JAMA Oncology
Retrospective Cohort Study: The incidence of ischemic stroke in patients with asymptomatic severe carotid stenosis (70% to 99%) without surgical intervention was 4.7% over 5 years.
25 May, 2022 | 11:48h | UTCIncidence of Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention – JAMA (free for a limited period)
News Release: Low stroke risk in patients with very narrowed neck arteries – Kaiser Permanente
USPSTF Recommendation Statement: The current evidence is insufficient to make a recommendation about screening for impaired visual acuity in older adults.
25 May, 2022 | 11:44h | UTCEditorials:
Visual Acuity Screening in Older Adults – JAMA Ophthalmology
Screening for Impaired Visual Acuity in Older Adults – JAMA
Evidence Report: Screening for Impaired Visual Acuity in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Patient Page: Screening for Impaired Visual Acuity in Older Adults – JAMA
Author Interview: USPSTF Recommendations: Screening for Primary Open-Angle Glaucoma and Screening for Impaired Visual Acuity in Older Adults – JAMA
USPSTF Recommendation Statement: The current evidence is insufficient to make a recommendation about screening for primary open-angle glaucoma in adults.
25 May, 2022 | 11:46h | UTCEditorials:
Identifying Glaucoma in Primary Care Offices – JAMA Ophthalmology
Evidence Report: Screening for Glaucoma in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Patient Page: Screening for Primary Open-Angle Glaucoma – JAMA
Author Interview: USPSTF Recommendations: Screening for Primary Open-Angle Glaucoma and Screening for Impaired Visual Acuity in Older Adults
Effectiveness of CoronaVac in children 3 to 5 years during the SARS-CoV-2 Omicron outbreak in Chile.
25 May, 2022 | 11:42h | UTC
RCT: Baricitinib vs. dexamethasone for adults hospitalized with COVID-19.
25 May, 2022 | 11:38h | UTC
Commentary on Twitter
?Just Out
ACTT-4 Trial?First Double Placebo-Controlled Double-Blind Randomized-Stratified Head-to-Head#DEXAMETHASONE vs #BARICITINIB for hospitalized pts w/#COVID19 Low/High-Flow/NIV
Relevant?Patient Care/Public Health/Guidelines
Our results
?https://t.co/4Tmue7HK7V
?1/4 pic.twitter.com/aF1Y7BAdu3— Andre Kalil, MD MPH (@DrAndreKalil) May 24, 2022
Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study.
25 May, 2022 | 11:34h | UTCRelated recommendations:
WHO Interim Guidance: Laboratory testing for the Monkeypox.
24 May, 2022 | 10:51h | UTCLaboratory testing for the monkeypox virus: Interim guidance – World Health Organization
Related:
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
Epidemiologist and health security expert says clinicians should prepare for Monkeypox.
24 May, 2022 | 10:49h | UTCNews Release: Epidemiologist and health security expert says clinicians should prepare for monkeypox – American College of Physicians
Original Article: A Novel International Monkeypox Outbreak – Annals of Internal Medicine
Related:
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
WHO Interim Guidance: Surveillance, case investigation and contact tracing for Monkeypox.
24 May, 2022 | 10:53h | UTCSurveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Related:
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
AHA Scientific Statement: Ambulatory blood pressure monitoring in children and adolescents.
24 May, 2022 | 10:47h | UTCNews Release: Statement updates ambulatory blood pressure classification in children and adolescents – American Heart Association
Top 100 most-cited articles on enhanced recovery after surgery.
24 May, 2022 | 10:38h | UTCSee also: Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines
Long-term follow up of RCT: Effects of long-term metformin and lifestyle interventions on cardiovascular events in the Diabetes Prevention Program and Its Outcome Study (DPPOS).
24 May, 2022 | 10:39h | UTCNews Release: Lifestyle changes, meds effective to prevent or delay Type 2 diabetes; no change in CVD – American Heart Association
Creating effective infographics and visual abstracts to disseminate research and facilitate medical education on social media.
24 May, 2022 | 10:46h | UTC
Commentary on Twitter
Creating Effective Infographics and Visual Abstracts to Disseminate Research and Facilitate Medical Education on Social Media
? Freely Available
? https://t.co/GpeoEQAWMP#IDTwitter
via @JenniferSpicer4 and @cg_coleman pic.twitter.com/DjiJbAyPVQ— Clinical Infectious Diseases (@CIDJournal) May 23, 2022
Cross-sectional study: assessment of perioperative outcomes among surgeons who operated the night before.
24 May, 2022 | 08:17h | UTCAssessment of Perioperative Outcomes Among Surgeons Who Operated the Night Before – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Are Surgeons Really More Resilient Than Athletes? The Trade-off Between Surgeon Outcomes and Surgeon Well-being – JAMA Internal Medicine (free for a limited period)
Author Interview: Assessment of Perioperative Outcomes Among Surgeons Who Operated the Night Before
Commentary on Twitter
This cross-sectional study found that operating overnight does not appear to be associated with worse outcomes when the attending surgeon continues to operate the next day. https://t.co/ahLoKav6HT
— JAMA Internal Medicine (@JAMAInternalMed) May 23, 2022