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AHA Scientific Statement: Cardiopulmonary consequences of vaping in adolescents.

23 Jun, 2022 | 13:03h | UTC

Cardiopulmonary Consequences of Vaping in Adolescents: A Scientific Statement From the American Heart Association – Circulation Research

News Release: Action needed to reduce e-cigarette use among adolescents to lower lifetime CVD risk – American Heart Association

 

Sleep-Related Infant Deaths: Updated AAP 2022 recommendations for reducing infant deaths in the sleep environment.

23 Jun, 2022 | 13:05h | UTC

Sleep-Related Infant Deaths: Updated 2022 Recommendations for Reducing Infant Deaths in the Sleep Environment – Pediatrics

Commentaries:

New safe-sleep guidelines aim to reduce infant deaths – University of Virginia Health System

AAP Updates Recommendations for Safe Infant Sleep Practices – HealthDay

 

Commentary on Twitter

 

RCT: Effect of MRI-guided fibrosis ablation vs. conventional catheter ablation on atrial arrhythmia recurrence in patients with persistent atrial fibrillation.

23 Jun, 2022 | 12:57h | UTC

Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The DECAAF II Randomized Clinical Trial – JAMA (free for a limited period)

News Release: Global AFib study finds simple approach is best for ablation procedures – Tulane University

 

Commentary on Twitter

 

RCT: Effectiveness and safety of early initiation of poststernotomy cardiac rehabilitation exercise training.

23 Jun, 2022 | 12:59h | UTC

Effectiveness and Safety of Early Initiation of Poststernotomy Cardiac Rehabilitation Exercise Training: The SCAR Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

 

Commentary on Twitter

 

Ivermectin for COVID-19 Cochrane review update: 11 trials and no evidence of benefit shown.

23 Jun, 2022 | 10:38h | UTC

News Release: Ivermectin for COVID-19 review update: 11 trials and no evidence of benefit shown – Liverpool School of Tropical Medicine

Original Article: Ivermectin for preventing and treating COVID‐19 – Cochrane Library

Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library

 

We don’t know whether most medical treatments work, and we know even less about whether they cause harm – new study.

23 Jun, 2022 | 10:32h | UTC

We don’t know whether most medical treatments work, and we know even less about whether they cause harm – new study – The Conversation

Original Study: Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis – Journal of Clinical Epidemiology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Systematic Review: SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19.

23 Jun, 2022 | 10:37h | UTC

SARS‐CoV‐2‐neutralising monoclonal antibodies to prevent COVID‐19 – Cochrane Library

Summary: Are laboratory-made COVID-19-specific monoclonal antibodies effective to prevent COVID-19 in adults? – Cochrane Library

 

Risk factors for SARS-CoV-2 related severe Multisystem Inflammatory Syndrome in Children investigated in a Swedish population-based study.

23 Jun, 2022 | 10:36h | UTC

News Release: Risk factors for severe COVID-19 complication in children investigated in Swedish population-based study – Karolinska Institutet

Original Study: Risk factors for multisystem inflammatory syndrome in children – A population-based cohort study of over 2 million children – The Lancet Regional Health Europe

 

M-A: Incidence and etiology of infant Gram-negative bacteremia and meningitis in children.

23 Jun, 2022 | 10:27h | UTC

Incidence and aetiology of infant Gram-negative bacteraemia and meningitis: systematic review and meta-analysis – Archives of Disease in Childhood

 

RCTs: Once daily oral relugolix combination therapy vs. placebo in patients with endometriosis-associated pain.

23 Jun, 2022 | 10:30h | UTC

Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies (SPIRIT 1 and 2) – The Lancet

Commentaries:

Relugolix combination therapy for endometriosis pain – The Lancet (free registration required)

Relugolix demonstrates positive phase 3 data as combination therapy for endometriosis pain – Contemporary OB/GYN

 

Commentary on Twitter

 

USPSTF Statement: The current evidence is insufficient to recommend vitamins for the prevention of cardiovascular disease or cancer.

22 Jun, 2022 | 12:21h | UTC

Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement – JAMA

Evidence Report and Systematic Review: Vitamin and Mineral Supplements for the Primary Prevention of Cardiovascular Disease and Cancer – JAMA

Patient Page: Vitamins and Minerals to Prevent Cardiovascular Disease and Cancer – JAMA

Editorial: Why Too Many Vitamins Feels Just About Right – JAMA Internal Medicine

Author Interview: Why Too Many Vitamins Feels Just About Right – JAMA

Commentary: Vitamins, Supplements Useless for Most People: Expert Panel – HealthDay

 

ASA and APSF statement on perioperative testing for the COVID-19 virus.

22 Jun, 2022 | 12:19h | UTC

ASA and APSF Statement on Perioperative Testing for the COVID-19 Virus – American Society of Anesthesiologists

Commentary: ASA, APST Update Perioperative SARS-CoV-2 Testing Recommendations – HealthDay

Related:

Surgical Triage and Timing for Patients with COVID: A Guidance Statement from the Society of Thoracic Surgeons – Annals of Thoracic Surgery

When to operate after SARS-CoV-2 infection? A review on the recent consensus recommendation of the DGC/BDC and the DGAI/BDA – Langenbeck’s Archives of Surgery

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 

Computing for Audiology: Smartphone tympanometer for diagnosing middle ear disorders.

22 Jun, 2022 | 12:16h | UTC

Performing tympanometry using smartphones – Communications Medicine

News Release: Computing for Audiology: Smartphone tympanometer for diagnosing middle ear disorders – Bioengineering

 

Commentary on Twitter

 

RCT: Spinal anesthesia is associated with more pain and prescription analgesic use after hip surgery compared to general anesthesia.

22 Jun, 2022 | 12:11h | UTC

News Release: Spinal Anesthesia Associated with More Pain, Prescription Analgesic Use After Hip Surgery Compared with General Anesthesia – American College of Physicians

Study: Pain, Analgesic Use, and Patient Satisfaction With Spinal Versus General Anesthesia for Hip Fracture Surgery: A Randomized Clinical Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Original Publication: Spinal Anesthesia or General Anesthesia for Hip Surgery in Older Adults – New England Journal of Medicine

Commentary: Spinal Anesthesia Tied to More Severe Pain After Hip Fracture Surgery – HealthDay

Related:

Long-term Survival after Combined Epidural–General Anesthesia or General Anesthesia Alone: Follow-up of a Randomized Trial – Anesthesiology

Delirium in Older Patients after Combined Epidural–General Anesthesia or General Anesthesia for Major Surgery: A Randomized Trial – Anesthesiology

Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial – JAMA

 

Cohort Study: Successful 10-second one-legged stance performance predicts survival in middle-aged and older individuals.

22 Jun, 2022 | 12:18h | UTC

Successful 10-second one-legged stance performance predicts survival in middle-aged and older individuals – British Journal of Sports Medicine

News Release: Inability to stand on one leg in mid to later life linked to higher risk of death – University fo Bristol

 

Commentary on Twitter

 

Self-care management of bothersome symptoms as recommended by clinicians for patients with a chronic condition: A Delphi study.

22 Jun, 2022 | 12:13h | UTC

Self-care management of bothersome symptoms as recommended by clinicians for patients with a chronic condition: A Delphi study – Heart & Lung

 

Cohort Study: Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA.

22 Jun, 2022 | 12:07h | UTC

Risk of myocarditis and pericarditis after the COVID-19 mRNA vaccination in the USA: a cohort study in claims databases – The Lancet

Commentaries:

COVID-19 mRNA vaccination and myocarditis or pericarditis – The Lancet

Myocarditis and Pericarditis After the COVID-19 mRNA Vaccination – American College of Cardiology

Related:

SARS-CoV-2 Vaccination and Myocarditis in a Nordic Cohort Study of 23 Million Residents – JAMA Cardiology

Myocarditis and pericarditis after COVID-19 vaccination: clinical management guidance for healthcare professionals – UK Health Security Agency

Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

Review: SARS-CoV-2 infection and COVID-19 vaccination in pregnancy.

22 Jun, 2022 | 12:09h | UTC

SARS-CoV-2 infection and COVID-19 vaccination in pregnancy – Nature Reviews Immunology

 

Review: Sex differences in sequelae from COVID-19 infection and in long COVID syndrome.

22 Jun, 2022 | 12:06h | UTC

Sex differences in sequelae from COVID-19 infection and in long COVID syndrome: a review – Current Medical Research and Opinion

Commentary: Women more likely to have long COVID, different symptom profile – CIDRAP

 

Comparing the Pfizer and Moderna Covid vaccines for young children.

22 Jun, 2022 | 12:02h | UTC

Comparing the Pfizer and Moderna Covid vaccines for young children – STAT

Related: FDA advisers OK COVID-19 vaccines for youngest kids – CIDRAP

 

Review: Health and clinical impacts of air pollution and linkages with climate change.

21 Jun, 2022 | 11:13h | UTC

Health and Clinical Impacts of Air Pollution and Linkages with Climate Change – NEJM Evidence

Editorial: Fossil-Fuel Pollution and Climate Change — A New NEJM Group Series

 

Commentary on Twitter

 

RCT: In people with HIV, treating precancerous anal lesions cuts risk of anal cancer by more than half.

21 Jun, 2022 | 11:11h | UTC

News Release: In people with HIV, treating precancerous anal lesions cuts risk of anal cancer by more than half – National Institutes of Health

Original Study: Treatment of Anal High-Grade Squamous Intraepithelial Lesions to Prevent Anal Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

https://twitter.com/NEJM/status/1537185690961686528

 

Review: Climate change, fossil-fuel pollution, and children’s health.

21 Jun, 2022 | 11:14h | UTC

Climate Change, Fossil-Fuel Pollution, and Children’s Health – New England Journal of Medicine

Editorial: Fossil-Fuel Pollution and Climate Change — A New NEJM Group Series

Commentary: Extreme heat poses significant and growing health risk to babies and children, study shows – CNN

 

Commentary on Twitter

 

RCT: Low-dose methylprednisolone does not improve outcomes in critically ill patients with severe community-acquired pneumonia.

21 Jun, 2022 | 11:04h | UTC

Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia – Intensive Care Medicine

 

M-A: Opioid versus opioid-free analgesia after surgical discharge.

21 Jun, 2022 | 11:08h | UTC

Opioid versus opioid-free analgesia after surgical discharge: a systematic review and meta-analysis of randomised trials – The Lancet (link to abstract – $ for full-text)

News Release: Taking opioids at home after surgery: More harms than benefits – McGill University Health Center

 

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