Editor's Choice | Page 56 of 113 | Links Medicus Content Curation & Alerts in Medicine

In an analysis of >20 million cardiovascular ED visits from 2016-2018, women presenting with ICH or aortic aneurysm/dissection had higher death risk than men, but lower risk when presenting with AF, acute MI, or cardiac arrest #AHAJournals https://t.co/MUmtG725FS

— JAHA (@JAHA_AHA) September 15, 2022

RCT | Cefepime/Enmetazobactam vs. Piperacillin/Tazobactam in patients with complicated urinary tract infections.

6 Oct, 2022 | 13:49h | UTC

Effect of Cefepime/Enmetazobactam vs Piperacillin/Tazobactam on Clinical Cure and Microbiological Eradication in Patients With Complicated Urinary Tract Infection or Acute Pyelonephritis: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Cefepime/Enmetazobactam for Complicated Urinary Tract Infections – JAMA (free for a limited period)

Commentary on Twitter

https://twitter.com/JAMA_current/status/1577372986188906522

RCT | Intravenous immune globulin reduces disease activity in dermatomyositis.

6 Oct, 2022 | 13:48h | UTC

Trial of Intravenous Immune Globulin in Dermatomyositis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

NEJM: trial of IVIG for autoimmune disorder dermatomyositis – MedicalResearch.com

IV Immune Globulin Bests Placebo for Dermatomyositis – Drugs.com

Cohort Study | Association of thoracic aortic aneurysm size with long-term patient outcomes.

6 Oct, 2022 | 13:47h | UTC

Association of Thoracic Aortic Aneurysm Size With Long-term Patient Outcomes: The KP-TAA Study – JAMA Cardiology (free for a limited period)

Commentary on Twitter

Risk of dissection is low for non-syndromic pts with ascending aortic aneurysm. Risk higher w larger size, but with a 6.0cm inflection point, early surgery for Pts <5.5 cm should be selective, as the risks from aortic surgery may outweigh the benefits. https://t.co/Mgf1TtHkzr

— JAMA Cardiology (@JAMACardio) October 5, 2022

ADA/KDIGO Consensus Report | Diabetes management in chronic kidney disease.

5 Oct, 2022 | 13:59h | UTC

Diabetes Management in Chronic Kidney Disease: A Consensus Report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO) – Kidney International

News Release: NEWS RELEASE: ADA & KDIGO Release Joint Consensus Report on Diabetes Management in CKD

World guidelines for falls prevention and management for older adults: a global initiative.

5 Oct, 2022 | 13:58h | UTC

World guidelines for falls prevention and management for older adults: a global initiative – Age and Ageing

RCT | A postoperative multimodal opioid-sparing protocol can reduce opioid consumption after knee or shoulder arthroscopy.

5 Oct, 2022 | 13:57h | UTC

Effect of a Postoperative Multimodal Opioid-Sparing Protocol vs Standard Opioid Prescribing on Postoperative Opioid Consumption After Knee or Shoulder Arthroscopy: A Randomized Clinical Trial – JAMA (free for a limited period)

News Release: Orthopedic surgery patients do fine without opioid painkillers – McMaster University

RCT | Topical antibiotics reduce the time to clinical cure in children with infective conjunctivitis.

5 Oct, 2022 | 13:55h | UTC

Effect of Topical Antibiotics on Duration of Acute Infective Conjunctivitis in Children: A Randomized Clinical Trial and a Systematic Review and Meta-analysis – JAMA Network Open

Commentaries:

Topical Antibiotics Linked With Reduced Duration of Acute Infective Conjunctivitis in Children – AJMC

Topical Antibiotics Shorten Duration of Conjunctival Symptoms – HealthDay

Commentary on Twitter

In this RCT and meta-analysis with 3 prior RCTs, children who received antibiotic eye drops had shorter duration of conjunctivitis vs. placebo. #OAResearch https://t.co/3mq5Fr8NDS

— JAMA Network Open (@JAMANetworkOpen) October 4, 2022

Cohort Study | Artificial intelligence-enabled retinal vasculometry for prediction of cardiovascular diseases.

5 Oct, 2022 | 13:53h | UTC

Artificial intelligence-enabled retinal vasculometry for prediction of circulatory mortality, myocardial infarction and stroke – British Journal of Ophthalmology

Editorial: The eyes as a window to the heart: looking beyond the horizon – British Journal of Ophthalmology

Commentary: AI eye checks can predict heart disease risk in less than minute, finds study – The Guardian

Retinal photograph-based deep learning predicts biological age, and stratifies morbidity and mortality risk.

An artificial intelligence system can help predict myocardial infarction through retinal scans and minimal personal information.

Study shows that the retinal age gap might be a potential biomarker of aging linked to increased mortality risk.

Expert consensus | Glycemic management of critically ill patients.

4 Oct, 2022 | 14:38h | UTC

Expert consensus on the glycemic management of critically ill patients – Journal of Intensive Medicine

The Lancet Commission | Traumatic brain injury: progress and challenges in prevention, clinical care, and research.

4 Oct, 2022 | 14:36h | UTC

Homepage: Traumatic brain injury: progress and challenges in prevention, clinical care, and research (free registration required for all articles)

Traumatic brain injury: progress and challenges in prevention, clinical care, and research – The Lancet Neurology

Traumatic brain injury advances since 2017: what has changed? – The Lancet Neurology

RCT | Intrapartum extended-release nifedipine to prevent severe intrapartum hypertension in patients with severe preeclampsia.

4 Oct, 2022 | 14:37h | UTC

Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hypertension Among Pregnant Individuals With Preeclampsia With Severe Features – Hypertension (link to abstract – $ for full-text)

News Release: Severe preeclampsia treated safely with nifedipine during labor and delivery – American Heart Association

AAP Clinical Report | Controlling and treating head lice in children and adolescents.

3 Oct, 2022 | 14:04h | UTC

Head Lice – Pediatrics

News Release: American Academy of Pediatrics Updates Report on Controlling and Treating Head Lice in Children, Adolescents – American Academy of Pediatrics

AAP Recommendations | Prevention of pediatric all-terrain vehicles related deaths and injuries.

3 Oct, 2022 | 14:05h | UTC

American Academy of Pediatrics Recommendations for the Prevention of Pediatric ATV-Related Deaths and Injuries – Pediatrics

Technical Report: A Comprehensive Report on All-Terrain Vehicles and Youth: Continuing Challenges for Injury Prevention – Pediatrics

Commentaries:

ATVs Are Not Safe for Children: AAP Policy Explained – Health Children

AAP Calls for Prevention of Pediatric ATV-Linked Deaths, Injuries – HealthDay

AAP Clinical Report | Evaluation for bleeding disorders in suspected child abuse.

3 Oct, 2022 | 14:03h | UTC

Evaluation for Bleeding Disorders in Suspected Child Abuse – Pediatrics’

Technical Report: Evaluating for Suspected Child Abuse: Conditions That Predispose to Bleeding – American Academy of Pediatrics

Commentary: AAP guidance helps distinguish bleeding disorders from abuse – MDedge

Consensus Recommendations | Priority activities to address acute kidney injury in children.

3 Oct, 2022 | 14:01h | UTC

Consensus-Based Recommendations on Priority Activities to Address Acute Kidney Injury in Children: A Modified Delphi Consensus Statement – JAMA Network Open

Invited Commentary: Highlights of Consensus-Based Recommendations for Acute Kidney Injury in Children – JAMA Network Open

Commentary on Twitter

https://twitter.com/JAMANetworkOpen/status/1575893237201600517

Cohort Study | Diabetes diagnosed at younger ages is associated with increased morbidity compared to diagnosis in older adults.

3 Oct, 2022 | 14:02h | UTC

Associations of Age at Diagnosis and Duration of Diabetes With Morbidity and Mortality Among Older Adults – JAMA Network Open

M-A of randomized trials | Colchicine and coronary heart disease risks.

3 Oct, 2022 | 14:00h | UTC

Colchicine and coronary heart disease risks: A meta-analysis of randomized controlled clinical trials – Frontiers in Cardiovascular Medicine

M-A: Colchicine after percutaneous coronary intervention significantly reduces the risk of major adverse cardiovascular events in patients with symptomatic coronary artery disease.

Expert Analysis | Colchicine in acute coronary syndrome: when to commence?

M-A: Colchicine in patients with coronary artery disease – “colchicine reduces the risk of myocardial infarction and stroke, but has a higher rate of gastrointestinal upset with no influence on all‐cause mortality”.

Review: Colchicine and the heart.

M-A: Colchicine administration for percutaneous coronary intervention

M-A: Efficacy and safety of low-dose colchicine in patients with coronary disease

Meta-analysis: Colchicine reduces new cardiovascular events in patients with coronary artery disease

Expert analysis: Efficacy and safety of colchicine in patients with chronic stable coronary disease

#ESCCongress – [Abstract Only] Randomized trial: Colchicine in patients with chronic coronary disease

#ESCCongress – Randomized trial: Colchicine not beneficial for patients with acute coronary syndrome

#ESCCongress – Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)

#AHA19 – [Abstract Only] Practice Changing? – Randomized Trial: Low-Dose Colchicine Improves Outcomes after Myocardial Infarction

Research: Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome

RCT | Induced hypothermia did not improve survival or functional outcomes after in-hospital cardiac arrest.

30 Sep, 2022 | 12:43h | UTC

Temperature Control After In-Hospital Cardiac Arrest: A Randomized Clinical Trial – Circulation (free for a limited period)

Hypothermic versus Normothermic Temperature Control after Cardiac Arrest – NEJM Evidence

ERC-ESICM guidelines on temperature control after cardiac arrest in adults – Intensive Care Medicine (if the link is paywalled, try this one)

Target temperature management following cardiac arrest: a systematic review and Bayesian meta-analysis – Critical Care

Targeted temperature management following out-of-hospital cardiac arrest: a systematic review and network meta-analysis of temperature targets – Intensive Care Medicine

Targeted Temperature Management for Cardiac Arrest Due to Non-shockable Rhythm: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Frontiers in Medicine

Effect of Moderate vs Mild Therapeutic Hypothermia on Mortality and Neurologic Outcomes in Comatose Survivors of Out-of-Hospital Cardiac Arrest: The CAPITAL CHILL Randomized Clinical Trial – JAMA

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine

Commentary on Twitter

New RCT of hypothermia (32-34°C) vs normothermia in IHCA 🧠❄️

👥 249 patients (25% shockable, 78% outside ICU/ED)
➡️ similar mortality at 180d (73% vs 71%)
➡️ similar favorable neuro outcome at 180d (23% vs 24%)

🔗 @CircAHA https://t.co/1Axq8a5Wrn #ResusTwitter @thiele_holger pic.twitter.com/Jh69CHuUWZ

— Tommaso Scquizzato, MD (@tscquizzato) September 29, 2022