Editor's Choice
Study | The future risk of cervical precancer among HPV–negative women is increased with a history of HPV–positive results.
1 Nov, 2022 | 12:13h | UTC
Strategies for de-implementation of low-value care—a scoping review.
1 Nov, 2022 | 12:12h | UTCStrategies for de-implementation of low-value care—a scoping review – Implementation Science
RCT | In hypoxemic patients after extubation, high-flow vs. Venturi mask oxygen therapy resulted in similar re-intubation rates.
1 Nov, 2022 | 12:11h | UTC
Guideline | Acute mesenteric ischemia.
31 Oct, 2022 | 13:58h | UTC
ACC Expert consensus for integrating atherosclerotic cardiovascular disease and multimorbidity treatment.
31 Oct, 2022 | 13:59h | UTC
Commentary on Twitter
.@ACCinTouch's newest Expert Consensus Decision Pathway, just published in #JACC, offers a comprehensive and integrative framework for treating patients with #ASCVD and multimorbidity. https://t.co/NAa1aP4OEx#ACCClinicalDoc #CardioTwitter @kofi_larry @virani_md @tygluckman pic.twitter.com/XPePHSwuFL
— JACC Journals (@JACCJournals) October 25, 2022
Perioperative mortality in pediatric patients: a systematic review of risk assessment tools for use in the preoperative setting.
31 Oct, 2022 | 13:57h | UTC
Commentary on Twitter
In a new systemic review of preexisting literature on the prediction of #mortality in #pediatric populations, all chosen models exhibited good performance. However, many had high or unclear risks of bias, and most had not been externally validated. https://t.co/dfw95xgd4y pic.twitter.com/9GxCzrsAD2
— Anesthesiology (@_Anesthesiology) October 21, 2022
M-A of RCT | Comparison of low carbohydrate vs. low fat diets in Type 2 DM.
31 Oct, 2022 | 13:55h | UTC
SR | Immediate versus delayed postpartum insertion of contraceptive implant and IUD for contraception.
31 Oct, 2022 | 13:56h | UTC
RCT | Effects of a low-carbohydrate dietary intervention on hemoglobin A1c.
31 Oct, 2022 | 13:54h | UTCSee also: Visual Abstract
News Release: At risk for diabetes? Cut the carbs, says new study – Tulane University
Commentaries:
Low-Carb Diet Promising for Lowering Blood Sugar in Prediabetes – TCTMD
Dose-reduced direct oral anticoagulants: practical considerations.
31 Oct, 2022 | 13:52h | UTC
RCT | Photodynamic vs. white-light-guided resection of first-diagnosis non-muscle-invasive bladder cancer.
31 Oct, 2022 | 13:51h | UTC
WHO Report | Fungal priority pathogens list to guide research, development and public health action.
28 Oct, 2022 | 13:31h | UTCNews Release: WHO releases first-ever list of health-threatening fungi – World Health Organization
Commentary on Twitter (thread – click for more)
Fungal pathogens can cause illnesses and death.
They are becoming increasingly common and resistant to treatment.Yet, too little is known about them.
The 🆕 WHO fungal priority pathogens list is an important step to boost urgently needed research:
📌 https://t.co/cXgj2HPZIc pic.twitter.com/4LgdIqf4Lo— World Health Organization (WHO) (@WHO) October 25, 2022
WHO | Global status report on physical activity 2022.
28 Oct, 2022 | 13:30h | UTCGlobal status report on physical activity 2022 – World Health Organization
News Release: WHO highlights high cost of physical inactivity in first-ever global report – World Health Organization
Commentary on Twitter
The cost of physical inactivity will reach over USD300 billion in 10 years if governments don’t take urgent action to encourage more physical activity among their populations.
The first-ever WHO Global status report on physical activity 2022 explains 👉https://t.co/eLeRuwqlMb pic.twitter.com/7DBzMEJFIF
— World Health Organization (WHO) (@WHO) October 19, 2022
RCT | Early active mobilization during mechanical ventilation in the ICU did not improve outcomes and increased adverse events.
28 Oct, 2022 | 13:28h | UTCEarly Active Mobilization during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/NEJM/status/1585246120963604481
RCT | Haloperidol for the treatment of delirium in ICU patients did not significantly improve outcomes.
28 Oct, 2022 | 13:29h | UTCHaloperidol for the Treatment of Delirium in ICU Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In this randomized trial, treatment with haloperidol did not increase the number of days alive and out of the hospital among ICU patients with delirium. #LIVES2022 https://t.co/SCRUg3ff9X pic.twitter.com/0dInueHE76
— NEJM (@NEJM) October 26, 2022
RCT | Spontaneous-breathing trials performed with pressure-support ventilation are no better than trials using a T-piece.
28 Oct, 2022 | 13:25h | UTCSpontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Among patients with a high risk of reintubation, spontaneous-breathing trials performed with pressure-support ventilation did not result in significantly fewer ventilator-free days at day 28 than T-piece trials. #LIVES2022 https://t.co/kqSDe3X89v pic.twitter.com/dCcPxdCWmJ
— NEJM (@NEJM) October 26, 2022
Systematic Review | Support for healthy breastfeeding mothers with healthy term babies.
28 Oct, 2022 | 13:23h | UTCSupport for healthy breastfeeding mothers with healthy term babies – Cochrane Library
Summary: Support for breastfeeding mothers – Cochrane Library
CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox.
28 Oct, 2022 | 13:21h | UTCCommentaries:
Clinicians at Low Risk of Acquiring Monkeypox From Patients – JAMA
Low risk of monkeypox spread noted in health workers – CIDRAP
Risk of Monkeypox Transmission Low in Health Care Settings – HealthDay
RCT | Pulmonary vein isolation plus individualized substrate ablation of atrial low-voltage myocardium reduced A-fib recurrence.
28 Oct, 2022 | 13:24h | UTCLow-Voltage Myocardium-Guided Ablation Trial of Persistent Atrial Fibrillation – NEJM Evidence
Commentary on Twitter
Original Article: “Low-Voltage Myocardium-Guided Ablation Trial of Persistent Atrial Fibrillation,” by @YanHuo2022 et al. https://t.co/OYqzAt7ks0#CardioTwitter #AFib #MedTwitter @tudresden_de @ThomasGaspar16 @purerfellner @EPyoungstar @UKSH_KI_HL @MedUni_Wien @KardiologieWien pic.twitter.com/0ly3pjNiPa
— NEJM Evidence (@NEJMEvidence) October 24, 2022
RCT | Selective decontamination of the GI tract did not significantly reduce mortality in ICU patients on mechanical ventilation.
27 Oct, 2022 | 12:40h | UTCEffect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
Related study: Association Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
M-A | Selective decontamination of the GI tract may reduce in-hospital mortality in ICU patients receiving mechanical ventilation.
27 Oct, 2022 | 12:39h | UTCAssociation Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Related Study: Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)
RCT | A lower oxygen saturation target did not improve outcomes after out-of-hospital cardiac arrest.
27 Oct, 2022 | 12:38h | UTCEffect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Early Oxygen Supplementation After Resuscitation From Cardiac Arrest – JAMA (free for a limited period)
Related:
Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one)
Retrospective Cohort Study | Association of ECMO with new mental health diagnoses in adult survivors of critical illness.
27 Oct, 2022 | 12:37h | UTCAssociation of Extracorporeal Membrane Oxygenation With New Mental Health Diagnoses in Adult Survivors of Critical Illness – JAMA (free for a limited period)
Editorial: Mental Health Outcomes Following Extracorporeal Membrane Oxygenation in Survivors of Critical Illness – JAMA (free for a limited period)
News Release: ECMO survivors have higher rate of new mental health diagnoses than other ICU survivors – Ottawa Hospital
Commentary from the author on Twitter (thread – click for more)
🧵 Long-term outcomes after #ECMO are lacking in the literature.
A brief thread on our new paper in @JAMA_current, looking at mental health outcomes in survivors after ECMO (OPEN ACCESS).
Thrilled to have presented the results live @ESICM #LIVES2022 https://t.co/xaqKxCky67 pic.twitter.com/4zUomfNE7K
— Shannon Fernando (@shanfernands) October 26, 2022
Review | Monkeypox.
27 Oct, 2022 | 12:36h | UTCMonkeypox – New England Journal of Medicine
Related:
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Commentary on Twitter
Monkeypox cases reported in the United Kingdom, Portugal, and Italy in May 2022 led the WHO to declare a global health emergency. The authors review the virology, epidemiology, clinical features, and treatment of monkeypox. https://t.co/dk2ZxxPsN7 pic.twitter.com/u3gzD6V7Bo
— NEJM (@NEJM) October 26, 2022
Cohort Study | Racial and ethnic differences in bystander CPR for witnessed cardiac arrest.
27 Oct, 2022 | 12:35h | UTCCommentary: Blacks, Hispanics Less Likely Than Whites to Receive Bystander CPR – HealthDay