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RCT | Colistin monotherapy vs. combination therapy for carbapenem-resistant organisms

13 Jan, 2023 | 13:36h | UTC

Colistin Monotherapy versus Combination Therapy for Carbapenem-Resistant Organisms – NEJM Evidence

Commentary: Colistin Alone or with Meropenem: Is More Better? – NEJM Journal Watch

Related: Colistin alone versus colistin plus meropenem for treatment of severe infections caused by carbapenem-resistant Gram-negative bacteria: an open-label, randomised controlled trial – The Lancet

 

Retrospective Study | Clinical features and management of individuals admitted to hospital with monkeypox

13 Jan, 2023 | 13:33h | UTC

Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study – The Lancet Infectious Diseases

 

Rapid review on monkeypox policies among the G20 nations: relevance to policy and practitioner

13 Jan, 2023 | 13:34h | UTC

Rapid review on monkeypox policies among the G20 nations: relevance to policy and practitioner – F1000 Research

 

RCT | A 24-week, all-oral regimen for rifampin-resistant tuberculosis

12 Jan, 2023 | 13:27h | UTC

A 24-Week, All-Oral Regimen for Rifampin-Resistant Tuberculosis – New England Journal of Medicine

Commentary: Trial results show superiority of shorter, all-oral treatment for drug-resistant TB – CIDRAP

 

WHO consolidated guidelines on tuberculosis | Drug-resistant tuberculosis treatment, 2022 update

12 Jan, 2023 | 13:30h | UTC

WHO consolidated guidelines on tuberculosis. Module 4: treatment – drug-resistant tuberculosis treatment, 2022 update – World Health Organization

See also:

– WHO consolidated guidelines on tuberculosis: module 1: prevention: tuberculosis preventive treatment

– WHO consolidated guidelines on tuberculosis: module 2: screening: systematic screening for tuberculosis disease

– WHO consolidated guidelines on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 2021 update

– WHO consolidated guidelines on tuberculosis: module 5: management of tuberculosis in children and adolescents

 

RCT | Early treatment with Molnupiravir did not reduce hospitalizations in high-risk adults with COVID-19

12 Jan, 2023 | 13:24h | UTC

Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial – The Lancet

Commentaries: 

Molnupiravir does not reduce COVID-19 hospitalisations or deaths in vaccinated, high risk people – National Institute for Health and Care Research

Molnupiravir doesn’t cut Omicron hospitalization, death but can speed recovery – CIDRAP

 

The dangers of non-randomized, observational studies: experience from the COVID-19 epidemic

12 Jan, 2023 | 13:26h | UTC

The dangers of non-randomized, observational studies: experience from the COVID-19 epidemic – Journal of Antimicrobial Chemotherapy

 

An evidence and consensus-based definition of “Second Victim”

12 Jan, 2023 | 13:21h | UTC

An Evidence and Consensus-Based Definition of Second Victim: A Strategic Topic in Healthcare Quality, Patient Safety, Person-Centeredness and Human Resource Management – International Journal of Environmental Research and Public Health

 

Cohort Study | Risk factors for suffocation and unexplained causes of infant deaths

12 Jan, 2023 | 13:18h | UTC

Risk Factors for Suffocation and Unexplained Causes of Infant Deaths – Pediatrics

Commentary: Risk Factors for Sleep-Related Suffocation, Infant Death Identified – HealthDay

Related: Sleep-Related Infant Deaths: Updated AAP 2022 recommendations for reducing infant deaths in the sleep environment.

 

Commentary on Twitter

 

RCT | Planned delivery for pre-eclampsia between 34 and 37 weeks of gestation

12 Jan, 2023 | 13:20h | UTC

Planned delivery for pre-eclampsia between 34 and 37 weeks of gestation: the PHOENIX RCT – Health Technology Assessment

Original Publication: Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial – The Lancet

 

RCT | Effect of pessary vs. surgery in patients with symptomatic pelvic organ prolapse

12 Jan, 2023 | 13:16h | UTC

Effect of Pessary vs Surgery on Patient-Reported Improvement in Patients With Symptomatic Pelvic Organ Prolapse: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentary: Findings question value of pessary for pelvic organ prolapse – MDedge

 

Commentary on Twitter

 

SR | Diagnostic errors in the emergency department

12 Jan, 2023 | 13:19h | UTC

Diagnostic Errors in the Emergency Department: A Systematic Review – Agency for Healthcare Research and Quality

 

RCT | Effect of a biopsychosocial intervention vs. postural therapy in patients with acute and subacute spine pain

12 Jan, 2023 | 13:15h | UTC

Effect of a Biopsychosocial Intervention or Postural Therapy on Disability and Health Care Spending Among Patients With Acute and Subacute Spine Pain: The SPINE CARE Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

See also: Visual Abstract

News Release: Randomized Trial Finds Therapies for Spine Pain Improved Disability and Quality of Life But Did Not Decrease Healthcare Spending – Brigham and Women’s Hospital

Commentary: Noninvasive Interventions Can Reduce Spine Pain Versus Usual Care – HealthDay

 

Commentary on Twitter

 

Statement | Pre-procedure and pre-admission COVID-19 testing no longer recommended for asymptomatic patients

11 Jan, 2023 | 14:36h | UTC

News Release: Pre-Procedure and Pre-Admission COVID-19 Testing No Longer Recommended for Asymptomatic Patients – Infection Control & Hospital Epidemiology

Recommendation Statement: Asymptomatic screening for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) as an infection prevention measure in healthcare facilities: Challenges and considerations – Infection Control & Hospital Epidemiology

Commentary: Infectious disease board recommends hospitals stop screening asymptomatic patients for Covid-19 – STAT

Related: Routine pre-operative Covid testing in elective surgeries: Is it worth it? – American Journal of Surgery

 

NICE Guideline | Thyroid cancer: assessment and management

11 Jan, 2023 | 14:34h | UTC

Thyroid cancer: assessment and management – National Institute for Health and Care Excellence

 

RCT | In patients with AF undergoing ablation, the addition of posterior wall isolation to pulmonary vein isolation (PVI) was not better than PVI alone

11 Jan, 2023 | 14:33h | UTC

Effect of Catheter Ablation Using Pulmonary Vein Isolation With vs Without Posterior Left Atrial Wall Isolation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The CAPLA Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Catheter Ablation for Persistent Atrial Fibrillation – JAMA (free for a limited period)

See also: Visual abstract

 

Review | Autism spectrum disorder

11 Jan, 2023 | 14:31h | UTC

Autism Spectrum Disorder: A Review – JAMA (free for a limited period)

 

Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis

11 Jan, 2023 | 14:30h | UTC

Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis – Circulation

News Release: Researchers study immune response, proteins in blood of young adults who develop rare complication after COVID vaccination – Mass General Brigham

Commentary: Free spike proteins in the blood appear to play a role in myocarditis post-COVID mRNA vaccine – News Medical

 

Review | Durability of vaccine-induced and natural immunity against COVID-19

11 Jan, 2023 | 14:29h | UTC

Durability of Vaccine-Induced and Natural Immunity Against COVID-19: A Narrative Review – Infectious Diseases and Therapy

 

Perspective | The limits of shared decision making

11 Jan, 2023 | 14:28h | UTC

The limits of shared decision making – BMJ Evidence-Based Medicine

 

RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis

11 Jan, 2023 | 14:27h | UTC

Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Weekly Dupilumab Beneficial in Eosinophilic Esophagitis – HealthDay

 

Monkeypox (hMPXV infection): a practical review

11 Jan, 2023 | 14:25h | UTC

Monkeypox (hMPXV infection): A practical review – American Journal of Medicine

 

SR | Efficacy of presurgical interventions to promote smoking cessation

11 Jan, 2023 | 14:24h | UTC

Efficacy of Presurgical Interventions to Promote Smoking Cessation: A Systematic Review – Anesthesia & Analgesia

 

Guideline Synopsis | Diabetes management in chronic kidney disease

10 Jan, 2023 | 14:52h | UTC

Diabetes Management in Chronic Kidney Disease: Synopsis of the KDIGO 2022 Clinical Practice Guideline Update – Annals of Internal Medicine

News Release: Group summarizes new guidelines for treating patients with diabetes and chronic kidney disease – American College of Physicians

Commentary: Layered Approach Recommended for Patients With Diabetes, CKD – HealthDay

Original Guideline: KDIGO 2022 Clinical practice guideline for diabetes management in chronic kidney disease.

 

AAP Guideline | Evaluation and treatment of children and adolescents with obesity

10 Jan, 2023 | 14:54h | UTC

Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity – Pediatrics

Executive Summary: Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity – Pediatrics

News Release: American Academy of Pediatrics Issues Its First Comprehensive Guideline on Evaluating, Treating Children and Adolescents With Obesity – American Academy of Pediatrics

Commentaries:

Childhood obesity requires early, aggressive treatment, new guidelines say – NPR

New guidance: Use drugs, surgery early for obesity in kids – Associated Press

 

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