Editor's Choice
RCT | Routine use of endometrial receptivity testing to guide the timing of frozen embryo transfer did not improve the rates of live birth
20 Jan, 2023 | 14:45h | UTCEffect of Timing by Endometrial Receptivity Testing vs Standard Timing of Frozen Embryo Transfer on Live Birth in Patients Undergoing In Vitro Fertilization: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary on Twitter
Study findings do not support routine use of receptivity testing to guide the timing of embryo transfer during in vitro fertilization. https://t.co/p8jqTpRAfV #Research
— JAMA (@JAMA_current) December 6, 2022
Perspective | Eight glasses of water myth
20 Jan, 2023 | 14:43h | UTCEight Glasses of Water Myth – Science-Based Medicine
RCT | Safety, efficacy, and tolerability of modified Atkins diet in persons with drug-resistant epilepsy
20 Jan, 2023 | 14:42h | UTCSafety, Efficacy, and Tolerability of Modified Atkins Diet in Persons With Drug-Resistant Epilepsy: A Randomized Controlled Trial – Neurology (link to abstract – $ for full-text)
News Release: Can diet combined with drugs reduce seizures? – American Academy of Neurology
Commentary: Modified Atkins Diet Plus Drug Therapy Beneficial in Drug-Resistant Epilepsy – HealthDay
RCT | Aspirin noninferior to low-molecular-weight heparin for thromboprophylaxis after a fracture
19 Jan, 2023 | 14:30h | UTCAspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: PREVENT CLOT Supports Aspirin for VTE Prevention in Trauma Fractures – TCTMD
Consensus Recommendations | Sick day medication guidance for people with diabetes, kidney, or cardiovascular disease
19 Jan, 2023 | 14:31h | UTC
Commentary on Twitter
Consensus Recommendations for Sick Day Medication Guidance for People With Diabetes, Kidney, or Cardiovascular Diseasehttps://t.co/wqgzRNwAWt @disasterpharmy @VerdinNancy @kelsea_drall @MaoliosaDonald @Ross_Tsuyuki @nipannu @UCalgaryMed @UAlberta_DoM #VisualAbstract pic.twitter.com/j8ZMzLSmxQ
— AJKD (@AJKDonline) December 7, 2022
Gestational age at birth and cognitive outcomes in adolescence: population based full sibling cohort study
19 Jan, 2023 | 14:27h | UTCEditorial: Gestational age at birth and school performance – The BMJ
News Release: Premature birth linked to poorer school grades in adolescence – BMJ
RCT | No difference in survival with Torsemide vs. Furosemide after discharge of patients hospitalized with heart failure
19 Jan, 2023 | 14:26h | UTCEffect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart Failure: The TRANSFORM-HF Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: TRANSFORM-HF—Can We Close the Loop on Diuretics in Heart Failure? – JAMA (free for a limited period)
News Release: Comparison of diuretics shows no difference in heart failure survival – NIH/National Heart, Lung and Blood Institute
Commentary on Twitter
Among patients discharged after hospitalization for heart failure, torsemide compared with furosemide did not result in a significant difference in all-cause mortality over 12 months. https://t.co/EwoVzRigkS pic.twitter.com/5dvhJ1oVaf
— JAMA (@JAMA_current) January 17, 2023
Use of wastewater for Mpox outbreak surveillance in California
19 Jan, 2023 | 14:24h | UTCUse of Wastewater for Mpox Outbreak Surveillance in California – New England Journal of Medicine
Related:
Opinion: Wastewater analysis can be a powerful public health tool—if it’s done sensibly.
CDC unveils its latest weapon in Covid-19 detection: wastewater.
[Preprint] Wastewater genomic testing can effectively track COVID-19 variants of concern.
Human Waste Could Be The Next Big Weapon in Controlling COVID-19 – TIME
Next steps for wastewater testing to help end this pandemic — and prevent the next one – STAT
The myriad ways sewage surveillance is helping fight COVID around the world – Nature
It’s time to begin a national wastewater testing program for Covid-19 – STAT
Coronavirus: Testing sewage an ‘easy win’ – BBC
Commentary on Twitter
In this report, the use of wastewater to conduct surveillance for the presence and spread of mpox in California is described. https://t.co/PJm8fwekxr pic.twitter.com/klzC0mbC0w
— NEJM (@NEJM) January 18, 2023
Study shows low diagnostic sensitivities of SARS-CoV-2 rapid antigen self-tests in asymptomatic individuals in the omicron period
19 Jan, 2023 | 14:23h | UTCCommentary: Study: COVID-19 rapid home tests not highly sensitive for Omicron – CIDRAP
Cohort Study | Analysis of Rituximab use and COVID-19 hospitalization or death in patients with multiple sclerosis
19 Jan, 2023 | 14:22h | UTC
Commentary on Twitter
Patients with MS on rituximab vaccinated for #COVID19 6 months before or after their last infusion had a much lower risk of COVID hospitalization – 1.4 vs 3.6 per 100 among unvaccinated people. https://t.co/am6hdSidMT
— JAMA Network Open (@JAMANetworkOpen) December 28, 2022
M-A | The effect of early active mobilization at 6 months after critical illness
19 Jan, 2023 | 14:21h | UTCThe Effect of Mobilization at 6 Months after Critical Illness — Meta-Analysis – NEJM Evidence
Related:
Early Active Mobilization during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In this systemic review and meta-analysis on early mobilization in the ICU, Paton et al. find no significant effect on days alive and out of hospital. However, they find a possibility that it might increase mortality and adverse events. https://t.co/NrzDi7Y5KY#CriticalCare pic.twitter.com/mOW6BF44qx
— NEJM Evidence (@NEJMEvidence) December 20, 2022
Metomidate PET-CT vs. adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial
19 Jan, 2023 | 14:19h | UTCNews Release: Ten-minute scan enables detection and cure of the commonest cause of high blood pressure – Queen Mary University of London
Study shows patients with circulating tumor DNA are at increased risk of relapse after surgery for resectable colorectal cancer
19 Jan, 2023 | 14:18h | UTCCommentary: Data Support ctDNA as a Prognostic Marker for Recurrence/Benefit in Colorectal Cancer – Cancer Network
Commentary on Twitter
In the observational arm of the CIRCULATE-Japan study, among patients with stage II-IV #ColorectalCancer, those with the presence of circulating #tumorDNA post-tumor resection have a high recurrence risk & are likely to benefit from adjuvant #chemotherapyhttps://t.co/hKlRt1ZW6T
— Nature Medicine (@NatureMedicine) January 17, 2023
WHO Report | Close to one billion people globally are served by health-care facilities with no electricity access or with unreliable electricity
18 Jan, 2023 | 14:42h | UTCExecutive Summary: Energizing health: accelerating electricity access in health-care facilities: executive summary – World Health Organization
Commentary on Twitter (thread – click for more)
Only half of hospitals in Sub-Saharan Africa have energy access with rural health facilities suffering the most.
🔌 Reliable electricity in health-care facilities is essential to save lives https://t.co/LeIlWdmO31 pic.twitter.com/HulrvN6RPF
— World Health Organization (WHO) (@WHO) January 14, 2023
ACG Clinical Guideline | Diagnosis and management of gastrointestinal subepithelial lesions
18 Jan, 2023 | 14:39h | UTC
Recurrent venous thromboembolism and bleeding with extended anticoagulation: the VTE-PREDICT risk score
18 Jan, 2023 | 14:37h | UTCSee calculator: https://vtepredict.com/
Commentary on Twitter
The effect of extended anticoagulant treatment for individual patients with venous thromboembolism: the results from the VTE-PREDICT risk score! #venous #thromboembolism #anticoagulant #bleeding #score#EHJ #cardiotwitter @ESC_Journals @escardio
https://t.co/u3NHWyB9rv pic.twitter.com/ifOFxaXV1I— EHJ Editor-in-Chief (@ehj_ed) January 17, 2023
ACC Guidelines Update | Diagnosis and management of celiac disease
18 Jan, 2023 | 14:40h | UTCCommentaries:
ACG Updates Clinical Guidance on Diagnosing Celiac Disease – HCP Live
RCT | Early high-flow nasal oxygen did not improve outcomes in hospitalized children with acute hypoxemic respiratory failure
18 Jan, 2023 | 14:34h | UTCEffect of Early High-Flow Nasal Oxygen vs Standard Oxygen Therapy on Length of Hospital Stay in Hospitalized Children With Acute Hypoxemic Respiratory Failure: The PARIS-2 Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
Cohort Study | Brain cancer after radiation exposure from CT examinations of children and young adults
18 Jan, 2023 | 14:36h | UTCBrain cancer after radiation exposure from CT examinations of children and young adults: results from the EPI-CT cohort study – The Lancet Oncology (link to abstract – $ for full-text)
Commentaries:
CT brain cancer risk quantified for children and young adults – medwire News
Abstracts written by ChatGPT fool scientists
18 Jan, 2023 | 14:29h | UTCAbstracts written by ChatGPT fool scientists – Nature
Original Study (preprint): Comparing scientific abstracts generated by ChatGPT to original abstracts using an artificial intelligence output detector, plagiarism detector, and blinded human reviewers – bioRxiv
Review | Surgical site infection prevention
18 Jan, 2023 | 14:31h | UTCSurgical Site Infection Prevention: A Review – JAMA (free for a limited period)
Author interview: Surgical Site Infection Prevention – JAMA
Related:
Global guidelines on the prevention of surgical site infection – World Health Organization
AAOS Guideline: Prevention of surgical site infections after major extremity trauma.
Report | The COVID-19 pandemic and the future of telemedicine
18 Jan, 2023 | 14:28h | UTCNews Release: New report looks to the future of telemedicine – Imperial College London
M-A | Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection
18 Jan, 2023 | 14:27h | UTCNews Release: COVID-19 infection at any time during pregnancy boosts mother’s risk of death – BMJ
Commentary: Getting COVID in Pregnancy Greatly Raises a Woman’s Odds for Death – HealthDay
Implementing human factors for patient safety in anesthesia: guidance for clinicians, departments and hospitals
17 Jan, 2023 | 13:33h | UTCSee also: Human factors in anaesthesia: a narrative review – Anaesthesia
News Release: New guidance to reduce human error and improve safety as UK health service struggles – The Association of Anaesthetists
Commentary on Twitter
https://twitter.com/Anaes_Journal/status/1613461758332510208
AAP Clinical Report | Use of point-of-care ultrasonography in the NICU for diagnostic and procedural purposes
17 Jan, 2023 | 13:32h | UTCUse of Point-of-Care Ultrasonography in the NICU for Diagnostic and Procedural Purposes – Pediatrics
Technical Report: Use of Point-of-Care Ultrasonography in the NICU for Diagnostic and Procedural Purposes – Pediatrics
News Release: AAP Issues Reports on Point-of-care Ultrasonography Applications in the NICU – American Academy of Pediatrics
Commentary on Twitter
https://twitter.com/aap_peds/status/1597612750804598787