Editor's Choice
At least 5 million children have lost a parent or caregiver due to COVID-19 since March 2020, updated figures suggest.
25 Feb, 2022 | 11:32h | UTCCommentaries:
Related:
More than 1.5 million children lost a primary or secondary caregiver due to the COVID-19 pandemic.
Covid-19 Has Created Thousands Of Newly Single Parents And Orphans
Commentary on Twitter (thread – click for more)
At least 5 million children have lost a parent or caregiver due to #COVID19 since March 2020, updated figures suggest.
Authors urge actions to prioritise affected children, incl. economic strengthening, enhanced community & family support, & education. https://t.co/1slpFhjDJd pic.twitter.com/AvEncg4Yx1
— The Lancet (@TheLancet) February 24, 2022
Meta-analysis of randomized trials: Effectiveness of physical activity interventions delivered or prompted by health professionals in primary care settings.
25 Feb, 2022 | 11:27h | UTCEditorial: Lack of physical activity is a global problem
News Release: Primary care exercise interventions help boost physical activity levels and reduce weight in adults – BMJ
Risk of cancer in regular and low meat-eaters, fish-eaters, and vegetarians: a prospective analysis of UK Biobank participants.
25 Feb, 2022 | 11:24h | UTCCommentaries:
Expert reaction to study looking at eating meat and risk of cancer – Science Media Centre
Low-meat and meat-free diets associated with lower overall cancer risk – Biomed Central
Commentary on Twitter
Study suggests being #vegetarian may be associated w/lower risk of #cancer
⬇️risk of #colorectalcancer in low meat 🥩 eaters consistent w/evidence of impact of meat
⬇️risk of postmenopausal #breastcancer in #vegetarian 🌱women may be explained by🔽BMIhttps://t.co/1uQfEFgoRT pic.twitter.com/VHhh9NbFSL
— Gil Morgan, MD (@weoncologists) February 25, 2022
Study suggests multisystem inflammatory syndrome in children (MIS-C) is rare among vaccinated teens.
25 Feb, 2022 | 11:29h | UTCCommentaries:
When vaccine adverse event reporting generates hope, not fear – The Lancet Child & Adolescent Health
MIS-C rare in COVID-vaccinated teens, study finds – CIDRAP
Vaccination Greatly Reduces Odds of MIS-C in Teens Who Get COVID – HealthDay
Commentary on Twitter
New study from @CDCgov finds that multi-system inflammatory syndrome in children (#MISC) is rare among 12 to 20-year-olds who have received #COVID19 vaccination (1.0 case per million individuals receiving one or more doses)https://t.co/BpsXSpMMcH
— The Lancet Child & Adolescent Health (@LancetChildAdol) February 23, 2022
Perspective: David Oliver: Has covid killed the medical conference?
25 Feb, 2022 | 11:26h | UTCDavid Oliver: Has covid killed the medical conference? – The BMJ
RCT: In comatose survivors of cardiac arrest, a strategy of suppressing rhythmic and periodic EEG activity with the use of antiseizure medication did not improve neurologic outcomes.
24 Feb, 2022 | 10:45h | UTCTreating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In trial of comatose patients after cardiac arrest, intensive antiseizure treatment adapted from protocols for status epilepticus did not result in fewer poor outcomes at 3 mos than standard treatment. https://t.co/dpH5cgwhvW pic.twitter.com/zVBHBYMRK9
— NEJM (@NEJM) February 23, 2022
Editorial: Addressing vaccine inequity — Covid-19 vaccines as a global public good.
24 Feb, 2022 | 10:41h | UTC
Previous population immunity and Covid-19 severity with Omicron variant in South Africa.
24 Feb, 2022 | 10:43h | UTCAudio Interview: Understanding the Omicron Variant of SARS-CoV-2
Commentary on Twitter
In Gauteng, South Africa, where the omicron variant was first identified, two thirds of unvaccinated residents were seropositive for SARS-CoV-2, which indicates past infection. Omicron peaked just 1 month after being detected. #COVID19 https://t.co/Z8qTI1DNkv pic.twitter.com/ZZv2xevacG
— NEJM (@NEJM) February 23, 2022
RCT: Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine.
24 Feb, 2022 | 10:20h | UTCCommentary: Suspend Methotrexate for RA Patients Getting COVID Vax?— It’s not a simple choice, Brazilian study suggests (free registration required)
[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.
24 Feb, 2022 | 10:30h | UTCFourth dose of COVID vaccine offers only slight boost against Omicron infection – Nature
Original Study: 4th Dose COVID mRNA Vaccines’ Immunogenicity & Efficacy Against Omicron VOC – medRxiv
Two large populational-based studies find a slightly increased risk of thrombotic events following AstraZeneca COVID-19 vaccination.
24 Feb, 2022 | 10:23h | UTCCommentaries:
Two Large Studies Affirm Rare Thrombosis Risk With ChAdOx1 COVID-19 Vax – TCTMD
Mortality from congenital Zika Syndrome — nationwide cohort study in Brazil.
24 Feb, 2022 | 10:18h | UTC
Ramadan fasting: recommendations for patients with cardiovascular disease.
24 Feb, 2022 | 10:17h | UTCRamadan fasting: recommendations for patients with cardiovascular disease – Heart
Related:
WHO Interim Guidance: Safe Ramadan Practices in the Context of the COVID-19
Position Statement: Guidance for People with Types 1 and 2 Diabetes Who Fast During Ramadan
Diabetes and Ramadan: Practical guidelines
Commentary on Twitter
Ramadan fasting: recommendations for patients with cardiovascular diseasehttps://t.co/genOJm0Vu4 pic.twitter.com/9E3awbPcvB
— Heart_BMJ (@Heart_BMJ) July 26, 2021
USPSTF Draft Statement: Statin use for the primary prevention of cardiovascular disease in adults.
23 Feb, 2022 | 10:45h | UTCCommentary: USPSTF Updates Guidance on Statins for Primary Prevention of CVD – HealthDay
WHO/UNICEF: More than half of parents and pregnant women exposed to aggressive formula milk marketing.
23 Feb, 2022 | 10:42h | UTCCommentary: Aggressive’ marketing of formula milk flouts code, warns WHO as it urges curbs – The Guardian
Commentary on Twitter
"We have been targeted with marketing from formula milk companies."
Over half of parents & pregnant women exposed to formula milk marketing, violating international standards and harming child health
-🆕 WHO, @UNICEF survey➡️ https://t.co/86Bf69PSeK#EndExploitativeMarketing pic.twitter.com/BuhQPgM3OX
— World Health Organization (WHO) (@WHO) February 22, 2022
AHA Scientific Statement: Strategies to reduce low-value cardiovascular care.
23 Feb, 2022 | 10:43h | UTCNews Release: Do you really need that test? New statement highlights need to reduce “low-value” heart care – American Heart Association
WHO: Here are the 16 ‘best buys’ to tackle non-communicable diseases.
23 Feb, 2022 | 10:19h | UTCWHO: Here Are The 16 ‘Best Buys’ To Tackle Non-Communicable Diseases – Forbes
Original Report: WHO Report | Saving lives, spending less: the case for investing in noncommunicable diseases.
RCT: Sublingual dexmedetomidine reduces mild to moderate acute agitation in patients with bipolar disorder.
23 Feb, 2022 | 10:18h | UTCEffect of Sublingual Dexmedetomidine vs Placebo on Acute Agitation Associated With Bipolar Disorder: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Sublingual Dexmedetomidine as a Potential New Treatment for Agitation – JAMA (free for a limited period)
Commentary on Twitter
Randomized clinical trial found sublingual #dexmedetomidine at a dose of 180 μg or 120 μg reduced mild to moderate agitation in patients with #bipolar disorder. https://t.co/1VK2e15F7s pic.twitter.com/0oHw6eVMIP
— JAMA (@JAMA_current) February 22, 2022
Large registry-based study in the U.S. suggests infertility treatments are associated with increased risks for pregnancy and vascular complications.
23 Feb, 2022 | 10:16h | UTCNews Release: Common infertility treatments may increase risks for pregnancy, vascular complications – American Heart Association
Commentary: Infertility treatments raise risk of heart and pregnancy complications, study finds – CNN
AGA clinical practice update on de-prescribing of proton pump inhibitors.
22 Feb, 2022 | 10:12h | UTCRelated:
Deprescribing proton pump inhibitors guideline
Review: Deprescribing Proton Pump Inhibitors
RCT: Full endoscopic discectomy non-inferior to open discectomy in patients with sciatica.
22 Feb, 2022 | 10:11h | UTC
Meta-analysis finds low risk of a second allergic reaction to SARS-CoV-2 mRNA vaccines in patients with an allergic reaction with the first dose.
22 Feb, 2022 | 10:05h | UTC
Commentary on Twitter
Systematic review and meta-analysis of 22 studies and 1366 patients found that there was a low risk of repeat allergic reaction to a second #COVID19 mRNA vaccine dose in people who had immediate allergic reaction with the first dose. https://t.co/NQSXBJwa6r
— JAMA Internal Medicine (@JAMAInternalMed) February 21, 2022
UK unveils game plan for ‘living with COVID’.
22 Feb, 2022 | 09:56h | UTCUK unveils game plan for ‘living with COVID’ – CIDRAP
See also:
All you need to know about the end of Covid rules in England – The Guardian
‘Living with Covid’ strategy could do more harm than good, say businesses and unions – The Guardian
Opinion by Dr. Eric Topol | Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed.
22 Feb, 2022 | 10:07h | UTCWhy one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed – The Guardian
Commentary from the author on Twitter (thread – click for more)
My new essay @guardian
"Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed"https://t.co/RaBUpET2CZ
Summarizes extensive new evidence that confirmed Prior Covid ("Natural Immunity" or NI) + 1-shot is as protective as 3-shots /1— Eric Topol (@EricTopol) February 20, 2022
Why does the Omicron sub-variant spread faster than the original?
22 Feb, 2022 | 09:55h | UTCWhy does the Omicron sub-variant spread faster than the original? – Nature
Related:
Covid-19: What do we know about omicron sublineages?
We regret to inform you that we are now discussing subvariants – Vox
Sudden rise of more transmissible form of Omicron catches scientists by surprise.
Omicron’s sister variant spreads faster. So why did the one we call Omicron hit first?
BA.2 is like Omicron’s sister. Here’s what we know about it so far – The Conversation