Critical Care & Emergencies (all articles)
ICU-based renal replacement therapy
25 Feb, 2021 | 08:23h | UTCICU-Based Renal Replacement Therapy – Critical Care Medicine
Commentary on Twitter
Renal Replacement in #ICU
📌history/development
📌(fast) evolution of tech & machines
📌pivotal role of nursing
📌mode: CRRT vs IHD
📌CRRT & blood purification
📌peds & neonates #PedsICU
📌complications
📌anticoagulation@CritCareMed #FOAMcc #FOANed #CCC50 https://t.co/NxC88pbIB6 pic.twitter.com/OGVkwkrjLi— M Velia Antonini (@FOAMecmo) February 4, 2021
Sepsis treatment: Another trial shows no benefit from the combination of Vitamin C, Thiamine, and Hydrocortisone
24 Feb, 2021 | 02:25h | UTCEffect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Hydrocortisone, Vitamin C, and Thiamine for Treatment of Sepsis: Making Evidence Matter
Related: The VITAMINS Randomized Clinical Trial: Vitamin C, Hydrocortisone, and Thiamine Not beneficial for Patients with Sepsis (study and commentaries)
Commentary on Twitter
VICTAS trial now in @JAMA_current. Is this the final nail in the coffin for HAT in sepsis? https://t.co/kDdmnIdC6s
— UGAC3 (@ugac3) February 23, 2021
Diverticulitis: Observational study in outpatients suggests amoxicillin-clavulanate is a safe and effective option compared with metronidazole-fluoroquinolone
24 Feb, 2021 | 02:16h | UTCCommentaries: Amoxicillin-clavulanate safe and effective compared with metronidazole-with-fluoroquinolone for diverticulitis – American College of Physicians AND Study supports fluoroquinolone-sparing treatment for diverticulitis – CIDRAP
How the COVID-19 pandemic will change the future of critical care
24 Feb, 2021 | 02:49h | UTCHow the COVID-19 pandemic will change the future of critical care – Intensive Care Medicine
Commentary on Twitter
Will #COVID19 change critical care?
➡️approach to crises
➡️flexible #ICU capacity/staff & safer design
➡️efficient supply/use of PPE, devices, consumables, meds
➡️triage principles
➡️communication
➡️end‐of‐life
➡️#AI, registries, agile collaborative RCTshttps://t.co/0aWmhQxItm pic.twitter.com/qFZCi4eYwM— Intensive Care Medicine (@yourICM) February 23, 2021
M-A: The diagnostic accuracy of noninvasive methods to measure the intracranial pressure
23 Feb, 2021 | 01:14h | UTC
RCT: Topical intranasal tranexamic acid does not reduce the need for nasal packing in epistaxis
21 Feb, 2021 | 22:02h | UTCThe Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary on Twitter
TXA wasn't better than placebo in epistaxis in this well done RCT https://t.co/qA3yEXyvaM
Excellent work @adamreuben + team
Many of us (myself included) believed TXA a game changer in epistaxis
This trial must make us reexamine our practice pic.twitter.com/5QQsihlGC6
— Anand Swaminathan MD MPH 🏳️🌈🇺🇦 (@EMSwami) February 20, 2021
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias
23 Feb, 2021 | 02:03h | UTCFDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
FDA Safety Alert: Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Related: “Racial Bias in Pulse Oximetry Measurement”. In two large cohorts, Black patients had nearly three times the frequency of occult hypoxemia that was not detected by pulse oximetry as White patients – New England Journal of Medicine (study and commentaries)
Editorial: Prophylactic anticoagulation for patients in hospital with covid-19
23 Feb, 2021 | 01:59h | UTCProphylactic anticoagulation for patients in hospital with covid-19 – The BMJ
Related: Full-dose Heparin best for moderate COVID-19 regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials AND Cohort study: Early initiation of prophylactic anticoagulation linked to reduced mortality in patients admitted to hospital with Covid-19
Expert consensus of data elements for collection for enhanced recovery after cardiac surgery
21 Feb, 2021 | 21:53h | UTCRelated: Enhanced Recovery After Surgery (ERAS) Guidelines for Perioperative Care in Cardiac Surgery (guideline and commentary) AND Enhanced Recovery After Cardiac Surgery (ERAS Cardiac) Recommendations: An Important First Step—But There Is Much Work to Be Done – Cardiothoracic and Vascular Anesthesia (free)
See also: Enhanced Recovery After Surgery (ERAS) Society Guidelines
Commentary on Twitter
Just published in @WorldJSurg
"Expert Consensus of Data Elements for Collection for Enhanced Recovery After Cardiac Surgery"
Available for free download here https://t.co/7L4evdqg0G pic.twitter.com/3XyKt6P6wv
— ERAS® Society (@ErasSociety) February 21, 2021
RCT: Five oral analgesics (including opioids) are equally effective for the treatment of acute musculoskeletal extremity pain in the emergency department
21 Feb, 2021 | 21:39h | UTCA Randomized Trial Comparing the Efficacy of Five Oral Analgesics for Treatment of Acute Musculoskeletal Extremity Pain in the Emergency Department – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Hot off the Press: A Randomized Trial Comparing the Efficacy of
Five Oral Analgesics for Treatment of Acute
Musculoskeletal Extremity Pain in the Emergency
Department https://t.co/qfUNn2TgZM @benjaminbwf pic.twitter.com/BzVM3W5F0L— AnnalsofEM (@AnnalsofEM) December 30, 2020
Intensive care management of patients with COVID-19: a practical approach
21 Feb, 2021 | 22:34h | UTCRelated Guideline: Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update AND Infographic
Current use of inotropes in circulatory shock
21 Feb, 2021 | 21:34h | UTCCurrent use of inotropes in circulatory shock – Annals of Intensive Care
COVID‐19 convalescent plasma: Interim recommendations from the AABB
19 Feb, 2021 | 02:56h | UTCCOVID‐19 convalescent plasma: interim recommendations from the AABB – Transfusion
News release: AABB panel issues interim recommendations for Covid-19 convalescent plasma use
SOFA score is not accurate enough for mortality prediction in severely ill patients with COVID-19 pneumonia
19 Feb, 2021 | 02:44h | UTC
Commentary on Twitter
'The discriminant accuracy of the #SOFA score for
mortality prediction in patients prior to intubation for#COVID-19 pneumonia was poor and significantly inferior to simply using age.' Age, apparently can't be used because 'discrimination'. #bioethics https://t.co/QJIxqupoVx— udo schuklenk 🏳️🌈🇨🇦🇦🇺🇩🇪 (@schuklenk) February 17, 2021
Review: Oxygen administration for patients with ARDS
19 Feb, 2021 | 02:24h | UTCOxygen administration for patients with ARDS – Journal of Intensive Care
RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19
18 Feb, 2021 | 03:20h | UTCEditorial: Vitamin D3 to Treat COVID-19: Different Disease, Same Answer
In this RCT a single high dose of #vitaminD3 (100K IU) raised mean serum 25OH D levels but had no effect on hospital LOS (primary outcome), in-hospital mortality, ICU admission, or need for mechanical ventilation (secondary outcomes) https://t.co/eozVaYnb25
— JAMA (@JAMA_current) February 17, 2021
M-A: The effect of convalescent plasma therapy on COVID-19 patient mortality
18 Feb, 2021 | 03:07h | UTCRelated study (not published yet) with conflicting results: RECOVERY trial: No Benefit from convalescent plasma in hospitalized patients with Covid-19 (news release and commentary)
Video: Emergency intubation in Covid-19
18 Feb, 2021 | 03:16h | UTCEmergency Intubation in Covid-19 – New England Journal of Medicine
Patient characteristics and clinical outcomes of Type 1 vs. Type 2 myocardial infarction
18 Feb, 2021 | 02:54h | UTCPatient Characteristics and Clinical Outcomes of Type 1 Versus Type 2 Myocardial Infarction – Journal of the American Academy of Cardiology (link to abstract – $ for full-text)
Commentary on Twitter
What are the patient characteristics & clinical outcomes of type 1 vs type 2 #cvMI in the U.S.? Over 200K+ are analyzed. Find out in this week’s issue of #JACC: https://t.co/trgZtKgbOy @CianPMcCarthy @mvaduganathan @JJheart_doc #HFWeek2021 #HeartMonth #CardioTwitter pic.twitter.com/dCdinfeNwE
— JACC Journals (@JACCJournals) February 16, 2021
Short review: Acute CV complications of hematopoietic stem cell transplantation
18 Feb, 2021 | 02:40h | UTCAcute CV Complications of Hematopoietic Stem Cell Transplantation – American College of Cardiology
Ocular MRI findings in patients with severe COVID-19
17 Feb, 2021 | 01:42h | UTCCommentaries: New COVID-19 side effect: MRI links severe infection to dangerous eye problems – Health Imaging AND MRI illuminates COVID-19’s negative impact on the eyes – AuntMinnie AND Windows of Infection: MRI Reveals COVID-19-Linked Eye Abnormalities – Diagnostic Imaging
Cardiac arrest in COVID-19: characteristics and outcomes of in- and out-of-hospital cardiac arrest
17 Feb, 2021 | 01:32h | UTC
Commentary on Twitter
#COVID19 was involved in at least 10% of all out-of-hospital cardiac arrests (OHCA) and 16% of intra-hospital cardiac arrests (IHCA) and, among #COVID_19 cases, 30-day mortality was increased 3.4-fold in OHCA & 2.3-fold in IHCA https://t.co/uS6rzTXuew#EHJ #ESCYoung @ehj_ed pic.twitter.com/QisuU9rsLT
— European Society of Cardiology Journals (@ESC_Journals) February 5, 2021
Incidence rate and clinical impacts of arrhythmia following COVID-19: a systematic review and meta-analysis of 17,435 patients
17 Feb, 2021 | 01:31h | UTC
Study: Obesity and risk of catheter-related infections in the ICU
16 Feb, 2021 | 01:46h | UTC
Commentary on Twitter
Obesity & intravascular catheter‑related infections in #ICU, post hoc analysis of 4 multicentric RCTs, largest dataset ever collected:
BMI ≥ 40? ⬆️risk!!
Preventive strategies, notably catheter care/dressing disruption, should focus on this pt population.https://t.co/ZxBFAxz2Je pic.twitter.com/7GHov7ewkr— Intensive Care Medicine (@yourICM) February 1, 2021
How effective is magnesium in for the treatment of migraine?
16 Feb, 2021 | 01:48h | UTCHow Effective is Magnesium in your MAGraine Cocktail? – Journal Feed
Original study: MAGraine: Magnesium compared to conventional therapy for treatment of migraines – American Journal of Emergency Medicine