Critical Care & Emergencies (all articles)
CDC Report: Allergic reactions including anaphylaxis after receipt of the first dose of Moderna COVID-19 vaccine
25 Jan, 2021 | 01:29h | UTCCommentary: CDC reports rare allergic reactions to Moderna’s Covid-19 vaccine – STAT
Systematic Review: Topical antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving mechanical ventilation
25 Jan, 2021 | 01:05h | UTC
5 Important Things To Know About Extended Spectrum Beta-Lactamases (ESBL): Insights From A Clinical Microbiologist
25 Jan, 2021 | 00:58h | UTC
[News release – Not published yet] Lilly’s neutralizing antibody prevented COVID-19 at nursing homes, reducing risk by up to 80 percent for residents
22 Jan, 2021 | 08:40h | UTCCommentaries: Eli Lilly says its monoclonal antibody prevented Covid-19 infections in clinical trial – STAT AND Expert reaction to press release from Lilly about their neutralising antibody bamlanivimab and results from the BLAZE-2 trial looking at prevention of COVID-19 in nursing homes in the US – Science Media Centre
Clinical update: Allergic reactions including anaphylaxis after receipt of the first dose of Pfizer-BioNTech COVID-19 vaccine
22 Jan, 2021 | 08:35h | UTCAuthor interview: COVID-19 Vaccine Safety–Anaphylaxis and Allergic Reactions
Large cohort study identifies the most common hospital complications associated with COVID-19
22 Jan, 2021 | 08:36h | UTCCommentaries: Analysis of patient data reveals most common complications of COVID-19 – Medical News Today AND Study confirms most common complications associated with COVID-19 – New Medical
Commentary on Twitter
Large study of patients in the US who contracted #COVID19 confirms complications. Most common: pneumonia, respiratory failure, kidney failure, and sepsis or systemic inflammation. Read the research: https://t.co/GUUO1pgU9E @FralickMike pic.twitter.com/ZeMWEl3fi7
— CMAJ (@CMAJ) December 8, 2020
Twenty articles that critical care clinicians should read about COVID-19
22 Jan, 2021 | 08:28h | UTCTwenty articles that critical care clinicians should read about COVID-19 – Intensive Care Medicine
Commentary on Twitter
Main early papers on #COVID19 & their findings, an overview:
➡️ manifestations of severe disease
➡️ pharmacological therapy
➡️ ventilatory support in pts with #SARSCoV2 related #ARDS
➡️ healthcare organization & healthcare worker stress#FOAMcc #COVIDFOAM https://t.co/PvwsKhHn9v pic.twitter.com/QVg4zXU5TT— Intens Care Med (@yourICM) January 4, 2021
Multi-organ point-of-care ultrasound for COVID-19 (PoCUS4COVID): international expert consensus
21 Jan, 2021 | 01:19h | UTC
Cohort study: Recipients of hematopoietic stem-cell transplantation who develop COVID-19 have poor overall survival
21 Jan, 2021 | 01:18h | UTC
Randomized trial: Similar outcomes with lower vs. higher oxygenation targets for acute hypoxemic respiratory failure
21 Jan, 2021 | 01:16h | UTCLower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Even though supplemental oxygen is used for the treatment of patients with hypoxemic respiratory failure, the most effective oxygenation targets are not known. In this randomized trial, a lower oxygenation target did not result in lower mortality than a higher target.
— NEJM (@NEJM) January 21, 2021
Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks
21 Jan, 2021 | 01:22h | UTC
Thrombolytic strategies versus standard anticoagulation for acute deep vein thrombosis of the lower limb
21 Jan, 2021 | 01:10h | UTCSummary: Thrombolysis for treatment of acute deep vein thrombosis – Cochrane Library
Randomized trial: In pediatric acute CNS infections, 3% Hypertonic saline is superior to 20% Mannitol for reducing intracranial pressure
21 Jan, 2021 | 01:08h | UTCRandomized Clinical Trial of 20% Mannitol Versus 3% Hypertonic Saline in Children With Raised Intracranial Pressure Due to Acute CNS Infections – Pediatric Critical Care Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Feature w/#VisualAbstract
RCT of 20% mannitol vs. 3% hypertonic saline in children w/raised ICP due to acute CNS infections: Which is superior?
Rameshkumar, @drarunbansal, Jayashree ??: https://t.co/ZGWaPMhPvr
Editorial by Argent ??: https://t.co/BsbZKsEG03#PedsICU @WFPICCS pic.twitter.com/5asM9HNQaN
— Pediatric Critical Care Medicine (@PedCritCareMed) December 21, 2020
Managing code status conversations for seriously ill older adults in respiratory failure
21 Jan, 2021 | 00:55h | UTC
Case series: Portable Magnetic Resonance Imaging for ICU Patients
21 Jan, 2021 | 00:54h | UTCPortable Magnetic Resonance Imaging for ICU Patients – Critical Explorations
Critical analysis of a randomized controlled trial
21 Jan, 2021 | 00:52h | UTCCritical Analysis of a Randomized Controlled Trial – Indian Journal of Critical Care Medicine
Randomized trial: No benefit from discontinuing ACE Inhibitors and ARBs in patients admitted with COVID-19
20 Jan, 2021 | 01:55h | UTCCommentary: Discontinuing vs. Continuing ACEIs, ARBs in Patients Admitted With COVID-19 – American College of Cardiology
Related study (study and commentary): Randomized trial: Renin–angiotensin system inhibitors can be safely continued in patients admitted to hospital with COVID-19
Study: Crowded ICUs linked to increased mortality from COVID-19
20 Jan, 2021 | 01:53h | UTCCommentaries: Intensive Care Unit Strain and Mortality Risk Among Critically Ill Patients With COVID-19—There Is No “Me” in COVID – JAMA Network Open AND Crowded ICUs tied to higher risk of COVID-19 death – CIDRAP
Randomized trial: Endovascular treatment alone noninferior to intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke
20 Jan, 2021 | 01:35h | UTCEffect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke: The DEVT Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke – JAMA (free for a limited period)
Video: Thrombolysis Before Thrombectomy for Stroke
Meta-analysis: Early initiation of renal replacement therapy is not associated with survival benefit in critically ill patients with acute kidney injury
20 Jan, 2021 | 01:25h | UTC
Meta-analysis: Inconclusive evidence regarding a benefit of systematic early mobilization in mechanically ventilated adult ICU patients
20 Jan, 2021 | 01:24h | UTC
Post-resuscitation shock: Recent advances in pathophysiology and treatment
20 Jan, 2021 | 01:18h | UTC
Meta-analysis: Corticosteroid use in COVID-19 patients
19 Jan, 2021 | 01:56h | UTCRelated meta-analysis: Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials – Journal of Cardiothoracic and Vascular Anesthesia
Evidence summary and clinical decision algorithm to guide clinicians in the care of the hypoxemic, non-intubated patients with suspected Covid-19
19 Jan, 2021 | 01:57h | UTC
After return of spontaneous circulation in patients with out-of-hospital cardiac arrest, too early ECG acquisition (7 minutes or less) is associated with false-positive findings for STEMI
19 Jan, 2021 | 01:44h | UTCCommentary: Delaying Electrocardiography in Cardiac Arrest: A Pause for the Cause – JAMA Network Open