RCT: Topical intranasal tranexamic acid does not reduce the need for nasal packing in epistaxis

The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary on Twitter

TXA wasn't better than placebo in epistaxis in this well done RCT https://t.co/qA3yEXyvaM

Excellent work @adamreuben + team

Many of us (myself included) believed TXA a game changer in epistaxis

This trial must make us reexamine our practice pic.twitter.com/5QQsihlGC6

— Anand Swaminathan (@EMSwami) February 20, 2021