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Critical Care & Emergencies (all articles)

Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup.

14 Jun, 2021 | 08:27h | UTC

Extracorporeal treatment for poisoning to beta-adrenergic antagonists: systematic review and recommendations from the EXTRIP workgroup – Critical Care

 

Non-invasive oxygenation strategies for respiratory failure with COVID-19: A concise narrative review of literature in pre and mid-COVID-19 era.

11 Jun, 2021 | 08:25h | UTC

Non-invasive Oxygenation Strategies for Respiratory Failure with COVID-19: A concise narrative review of literature in pre and mid-COVID-19 era – Anaesthesia Critical Care & Pain Medicine

 

CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare.

11 Jun, 2021 | 08:28h | UTC

CDC says heart inflammation cases were higher than expected in 16- to 24-year-olds after second Covid vaccine shot, but still rare – CNBC

See also: CDC plans “emergency meeting” on rare heart inflammation following COVID-19 vaccines – CBC News

Related: Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men.

 

RCT: In patients with atrial fibrillation or mechanical heart valves treated with warfarin undergoing surgery, postoperative bridging treatment with low molecular weight heparin did not prevent major thromboembolism.

11 Jun, 2021 | 08:19h | UTC

Postoperative low molecular weight heparin bridging treatment for patients at high risk of arterial thromboembolism (PERIOP2): double blind randomised controlled trial – The BMJ

 

Commentary on Twitter

 

M-A: Safety of thoracentesis and tube thoracostomy in patients with uncorrected coagulopathy.

11 Jun, 2021 | 08:15h | UTC

Safety of Thoracentesis and Tube Thoracostomy in Patients With Uncorrected Coagulopathy: A Systematic Review and Meta-analysis – CHEST

Commentary: Is Thoracentesis Safe in Coagulopathic Patients? – JournalFeed

 

M-A: Mental health interventions may improve psychological outcomes in informal caregivers of critically ill patients.

11 Jun, 2021 | 08:14h | UTC

Mental Health Interventions to Improve Psychological Outcomes in Informal Caregivers of Critically Ill Patients: A Systematic Review and Meta-Analysis – Critical Care Medicine

 

Commentary on Twitter

https://twitter.com/stephanajulia/status/1381591004776595458

 

The furosemide stress test: current use and future potential.

11 Jun, 2021 | 08:12h | UTC

The furosemide stress test: current use and future potential – Renal Failure

 

Case series: Adjunct immune globulin for vaccine-induced thrombotic thrombocytopenia.

10 Jun, 2021 | 09:46h | UTC

Adjunct Immune Globulin for Vaccine-Induced Thrombotic Thrombocytopenia – New England Journal of Medicine

 

[Preprint] RECOVERY trial finds aspirin does not improve survival for patients hospitalized with COVID-19.

9 Jun, 2021 | 08:28h | UTC

News Release: RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19 – University of Oxford

Original Study: Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial – medRxiv

 

Commentary on Twitter (thread – click for more)

 

COVID-19 Imaging: What we know now and what remains unknown.

9 Jun, 2021 | 08:27h | UTC

COVID-19 Imaging: What We Know Now and What Remains Unknown – Radiology

 

M-A: Hospital-at-home interventions for patients with chronic disease who present to the emergency department – similar mortality risk, lower risk for readmission, lower depression and anxiety scores, and a lower risk for long-term care admission vs. in-hospital stay.

9 Jun, 2021 | 08:20h | UTC

Hospital-at-Home Interventions vs In-Hospital Stay for Patients With Chronic Disease Who Present to the Emergency Department: A Systematic Review and Meta-analysis – JAMA Network Open

Invited commentary: Hospitalization at Home for Patients With Acute Exacerbation of Chronic Disease—Further Evidence to Inform Practice – JAMA Network Open

Related: Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient AND Randomized trial: Admission Avoidance Hospital at Home + Geriatric Assessment led to similar outcomes compared to hospital admission for older persons AND Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – Approximately 1 in 5 were admitted within 14 days. Higher oxygen saturation was associated with decreased odds of transfer, whereas higher comorbidity burden was associated with increased risk.

 

Short review: Neurological complications of COVID-19.

8 Jun, 2021 | 09:36h | UTC

Neurological complications of COVID-19 – Intensive Care Medicine

 

Commentary on Twitter

 

The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – careful use of antibiotics and corticosteroids and closely monitoring blood glucose levels are some of the strategies suggested by the authors.

8 Jun, 2021 | 09:34h | UTC

The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – Annals of Internal Medicine

 

Multicenter Epidemiologic Study of Coronavirus Disease–Associated Mucormycosis, India – Uncontrolled diabetes mellitus was the most common underlying disease; improper glucocorticoid use was independently associated with the disease.

8 Jun, 2021 | 09:33h | UTC

Multicenter Epidemiologic Study of Coronavirus Disease–Associated Mucormycosis, India – CDC Emerging Infectious Diseases

Commentary: COVID19: Secondary Infections Still a Big Challenge in India – News Click

 

Commentary on Twitter

 

Time-to-positivity in bloodstream infection is not a prognostic marker for mortality: analysis of a prospective multicenter randomized control trial.

8 Jun, 2021 | 09:21h | UTC

Time-to-positivity in bloodstream infection is not a prognostic marker for mortality: analysis of a prospective multicentre randomised control trial – Clinical Microbiology and Infections

 

Commentary on Twitter

 

RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk.

7 Jun, 2021 | 00:01h | UTC

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial – The Lancet

Related: #ACC21 – [Not published yet] RCT: Among hospitalized patients with Covid-19 and elevated D-Dimer, therapeutic anticoagulation with Rivaroxaban 20 mg was not associated with improved outcomes and resulted in increased major bleeding.

 

Commentary on Twitter

https://twitter.com/RenatoDLopes1/status/1400962037610582026

 

Case report: Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT).

6 Jun, 2021 | 23:55h | UTC

Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT) – Journal of Thrombosis and Haemostasis

Commentary: COVID-19 vaccination: Thrombosis can be prevented by prompt treatment, researchers report – Medical University of Vienna

 

RCT: Early, intensive mobilization poststroke may harm patients.

6 Jun, 2021 | 23:45h | UTC

Fatal and Nonfatal Events Within 14 days After Early, Intensive Mobilization Poststroke – Neurology

 

Moving from bytes to bedside: a systematic review on the use of artificial intelligence in the intensive care unit.

6 Jun, 2021 | 23:42h | UTC

Moving from bytes to bedside: a systematic review on the use of artificial intelligence in the intensive care unit – Intensive Care Medicine

 

Commentary on Twitter

 

M-A: The benefit of dysphagia screening in adult patients with stroke.

6 Jun, 2021 | 23:43h | UTC

The Benefit of Dysphagia Screening in Adult Patients With Stroke: A Meta‐Analysis – Journal of the American Heart Association

 

Another study shows a high frequency of antibiotic use among patients hospitalized with Covid-19 (85.2%), despite low rates of confirmed secondary bacterial infections.

4 Jun, 2021 | 10:43h | UTC

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study – The Lancet Microbe

Commentaries: Very high use of antibiotics in COVID-19 treatment could be reduced – University of Glasgow AND More evidence of frequent antibiotic use noted in COVID patients – CIDRAP AND Covid-19: Antimicrobial use was high during first wave despite bacterial co-infections being rare, study finds – The BMJ

Related: Many hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT

 

Commentary on Twitter (thread – click for more)

 

M-A: Prehospital Tranexamic Acid reduces mortality among bleeding trauma patients without increasing the risk of venous thromboembolism.

6 Jun, 2021 | 23:34h | UTC

The impact of prehospital TXA on mortality among bleeding trauma patients: A systematic review and meta-analysis – Journal of Trauma and Acute Care Surgery (link to abstract – $ for full-text)

Commentary: Prehospital TXA for Trauma – Meta-analysis – JournalFeed

 

In a Mendelian randomization study, researchers found no genetic evidence to support an association between Vitamin D levels and COVID-19 susceptibility, severity, or hospitalization.

4 Jun, 2021 | 10:35h | UTC

Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study – PLOS Medicine

Commentary: Vitamin D may not provide protection from COVID-19 susceptibility or disease severity, study suggests – PLOS

Related: Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19. AND RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19

 

Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients.

4 Jun, 2021 | 10:26h | UTC

Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients – Annals of Intensive Care

 

RCT: No benefit from passive leg raising during cardiopulmonary resuscitation in out-of-hospital cardiac arrest.

4 Jun, 2021 | 10:28h | UTC

Clinical outcomes and safety of passive leg raising in out-of-hospital cardiac arrest: a randomized controlled trial – Critical Care

 

Commentary on Twitter

 

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