Critical Care & Emergencies (all articles)
SAEM Guidelines for reasonable and appropriate care in the emergency department (GRACE): Recurrent, low-risk chest pain in the emergency department.
7 Jul, 2021 | 08:48h | UTCNews release: SAEM publishes GRACE guidelines for recurrent, low-risk chest pain care in the ED – Society for Academic Emergency Medicine
Invited commentaries: GRACE-recurrent low-risk chest pain: A user’s guide AND Navigating uncertainty with GRACE: Society for Academic Emergency Medicine’s guidelines for reasonable and appropriate care in the emergency department
M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.
7 Jul, 2021 | 08:52h | UTC
RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19.
6 Jul, 2021 | 10:16h | UTCCommentary: Ivermectin: balance of evidence shows no significant benefit against Covid-19 – MSN News
Related: Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – “IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease”. AND Ivermectin is the new hydroxychloroquine, take 2 – “Ivermectin shouldn’t be used to treat COVID-19 outside of the context of a well-designed clinical trial”. AND Therapeutics and COVID-19 | WHO guideline update advises Ivermectin should only be used to treat COVID-19 within clinical trials AND RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19
Choosing Wisely for COVID-19: ten evidence-based recommendations for patients and physicians.
6 Jul, 2021 | 10:21h | UTC
Editorial | Do not just sit there, do something … but do no harm: the worrying aspects of COVID-19 experimental interventions.
6 Jul, 2021 | 10:14h | UTC
Commentary on Twitter
Shortcutting science perpetuates ineffective/unsafe treatments: with #COVID19 plethora of interventions (most next-to-no basis/inconsistent effects) trialled or given on compassionate grounds regardless risks. Will mistakes be acknowledged & lessons learnt?https://t.co/p53WyeMLEC pic.twitter.com/zUwlML8Pft
— Intens Care Med (@yourICM) July 5, 2021
WSES position paper: Diagnosis and management of small bowel obstruction in virgin abdomen.
6 Jul, 2021 | 10:07h | UTC
Energetic dysfunction in sepsis: a narrative review.
6 Jul, 2021 | 10:06h | UTCEnergetic dysfunction in sepsis: a narrative review – Annals of Intensive Care
M-A of observational studies: the association between surgical fixation of hip fractures within 24 hours and mortality.
6 Jul, 2021 | 10:01h | UTCThe association between surgical fixation of hip fractures within 24 hours and mortality: a systematic review and meta-analysis – The Bone & Joint Journal (link to abstract – $ for full-text)
CDC Report: Underlying medical conditions and severe illness among 540,667 adults hospitalized with COVID-19, March 2020–March 2021.
5 Jul, 2021 | 02:40h | UTC
Commentary on Twitter
A new report finds that obesity, diabetes with complication, and the presence of multiple chronic conditions were the strongest chronic risk factors for death from #COVID19 among hospitalized adults. Learn more: https://t.co/KzsarYhHYA. pic.twitter.com/c0vd8ANqa0
— CDC (@CDCgov) July 1, 2021
RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.
5 Jul, 2021 | 02:24h | UTC
Seminar | Acute respiratory distress syndrome.
5 Jul, 2021 | 01:57h | UTCAcute respiratory distress syndrome – The Lancet
Review | Perioperative cardiac risk reduction in noncardiac surgery.
5 Jul, 2021 | 01:45h | UTCPerioperative Cardiac Risk Reduction in Noncardiac Surgery – Mayo Clinic Proceedings
Acute kidney injury in the critically ill: an updated review on pathophysiology and management.
5 Jul, 2021 | 01:49h | UTC
Commentary on Twitter
#AKI in #ICU
➡️phenotypes
➡️pathophysiology
➡️impact on acute & long-term prognosis
➡️update on nephrotoxicity
➡️organ cross‑talk
➡️prevention: fluids/vasopressors management & kidney perfusion pressure
➡️prediction from biomarkers to #AI
➡️approach
➡️#RRThttps://t.co/Qyb7BQPTUn pic.twitter.com/ClDaBZLPa4— Intens Care Med (@yourICM) July 2, 2021
M-A: Decision-making authority during Tele-ICU care reduces mortality and length of stay.
5 Jul, 2021 | 01:18h | UTCDecision-Making Authority During Tele-ICU Care Reduces Mortality and Length of Stay—A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Vaccine-induced immune thrombotic thrombocytopenia (VITT) – a novel clinico-pathological entity with heterogeneous clinical presentations.
2 Jul, 2021 | 11:39h | UTCCommentary: Blood clots related to AstraZeneca/Oxford vaccine can be mitigated with early detection – MedicalXpress
Delirium in COVID-19: can we make the unknowns knowns?
2 Jul, 2021 | 11:17h | UTCDelirium in COVID-19: can we make the unknowns knowns? – Intensive Care Medicine
Commentary on Twitter
Delirium in #COVID19 critical illness?
➡️high incidence likely due to microvascular disease & inflammatory mechanisms
⬇️standards of care ie strained resources
➡️key predictor of cognitive impairment/dementia post ?
➡️long-term post #ICU follow-up pivotal https://t.co/dC339XrfGm pic.twitter.com/nzyPCu16ap— Intens Care Med (@yourICM) June 30, 2021
Perspective | Why no one is sure if Delta is deadlier – “The variants are spreading faster, but they don’t necessarily have incentive to kill more often”.
1 Jul, 2021 | 09:52h | UTCWhy No One Is Sure If Delta Is Deadlier – The Atlantic
AHA Scientific Statement: Managing atrial fibrillation in patients with heart failure and reduced ejection fraction.
1 Jul, 2021 | 09:46h | UTCTop Things to Know: Managing Atrial Fibrillation in Patients With Heart Failure and Reduced Ejection Fraction
Commentary on Twitter
Pleased to share AHA Scientific statement on ‘Managing AF in pts with HFrEF’ just published @CirculationEP. https://t.co/WRx3QnrxHF Many thanks to the writing group and reviewers for making this excellent guidance document possible @AHAScience @American_Heart @CircAHA #Epeeps pic.twitter.com/PoqqlyA0iA
— Rakesh Gopinath (@drrakeshg1) June 23, 2021
M-A: Simultaneous use of hypertonic saline and IV furosemide for fluid overload – “Benefits of the HSS+Fx over Fx were observed across all examined outcomes in acute decompensated heart failure patients with fluid overload”.
1 Jul, 2021 | 09:41h | UTCSimultaneous Use of Hypertonic Saline and IV Furosemide for Fluid Overload: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Case Series: Myocarditis following immunization with mRNA COVID-19 vaccines.
30 Jun, 2021 | 10:22h | UTCSee also: Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination – JAMA Cardiology
Editorials: Myocarditis Occurring After Immunization With mRNA-Based COVID-19 Vaccines AND Temporal Associations Between Immunization With the COVID-19 mRNA Vaccines and Myocarditis: The Vaccine Safety Surveillance System Is Working
Commentary: More Evidence Links Myocarditis to mRNA COVID-19 Vaccines – TCTMD
Commentary on Twitter
2 new reports of myocarditis after mRNA vaccination documenting its rare occurrence
23 males serving in the military among 2.8 million doses givenhttps://t.co/yPbYxkuSHi
4 cases in North Carolina, including a 70-year-old womanhttps://t.co/Iwj2Hx6O2U@JAMACardio pic.twitter.com/fv2JoOFAyt— Eric Topol (@EricTopol) June 29, 2021
Covid: Masks upgrade cuts infection risk, research finds.
30 Jun, 2021 | 10:16h | UTCCovid: Masks upgrade cuts infection risk, research finds – BBC
Pulmonary embolism in patients with COVID-19: incidence, risk factors, clinical characteristics, and outcome.
30 Jun, 2021 | 10:13h | UTC
Consensus Statement: The role of lung ultrasound in COVID-19 disease.
30 Jun, 2021 | 10:12h | UTCThe role of lung ultrasound in COVID-19 disease – Insights into Imaging
M-A: The utility of the rapid shallow breathing index in predicting successful extubation – “As a stand-alone test, the RSBI has moderate sensitivity and poor specificity for predicting extubation success”.
30 Jun, 2021 | 10:07h | UTCThe Utility of the Rapid Shallow Breathing Index in Predicting Successful Extubation: A Systematic Review and Meta-analysis – CHEST (link to abstract – $ for full-text)
Case report: Thrombosis with Thrombocytopenia After the Messenger RNA–1273 Vaccine.
29 Jun, 2021 | 10:07h | UTCThrombosis With Thrombocytopenia After the Messenger RNA–1273 Vaccine – Annals of Internal Medicine