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Critical Care & Emergencies (all articles)

RCT | Higher protein dosing did not improve outcomes in critically ill patients with high nutritional risk

27 Jan, 2023 | 12:24h | UTC

The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter (thread – click for more)

 

Perspective | Is it time to retire the diagnosis “hypertensive emergency”?

27 Jan, 2023 | 12:26h | UTC

Is it Time to Retire the Diagnosis “Hypertensive Emergency”? – Journal of the American Heart Association

 

CT imaging of the larynx for may be a tool for the diagnosis of vocal cord dysfunction

27 Jan, 2023 | 12:13h | UTC

Computed Tomography Imaging of the Larynx for Diagnosis of Vocal Cord Dysfunction – NEJM Evidence (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Review | The blood–brain barrier and optimization of antibiotics for the treatment of CNS infections in adults

27 Jan, 2023 | 11:55h | UTC

The Blood–Brain Barrier and Pharmacokinetic/Pharmacodynamic Optimization of Antibiotics for the Treatment of Central Nervous System Infections in Adults – Antibiotics

 

RCT | Continued enteral nutrition until extubation was noninferior to a 6-h fasting strategy before extubation in patients in the ICU

26 Jan, 2023 | 12:49h | UTC

Continued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial – The Lancet Respiratory Medicine (free registration required)

Invited Commentary: Continuation of enteral nutrition until extubation in critically ill patients – The Lancet Respiratory Medicine

 

Commentary on Twitter

 

Review | Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT)

26 Jan, 2023 | 12:46h | UTC

Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT) – Blood

 

Evidence-Based Guidance | Medical nutrition therapy in ECMO patients

26 Jan, 2023 | 12:28h | UTC

Medical Nutrition Therapy in ECMO Patients: Evidence-Based Guidance for Clinical Practice – Journal of Parenteral and Enteral Nutrition

 

Cohort study | Endovascular balloon occlusion of the aorta may be an alternative to resuscitative thoracotomy in traumatic hemorrhagic shock

26 Jan, 2023 | 12:18h | UTC

Zone 1 Endovascular Balloon Occlusion of the Aorta vs Resuscitative Thoracotomy for Patient Resuscitation After Severe Hemorrhagic Shock – JAMA Surgery (link to abstract – $ for full-text)

Related: Systematic review to evaluate algorithms for REBOA use in trauma and identify a consensus for patient selection – Trauma Surgery and Acute Care Open

 

Commentary on Twitter

 

Systematic review to evaluate algorithms for REBOA use in trauma and identify a consensus for patient selection

26 Jan, 2023 | 12:13h | UTC

Systematic review to evaluate algorithms for REBOA use in trauma and identify a consensus for patient selection – Trauma Surgery and Acute Care Open

Related: Zone 1 Endovascular Balloon Occlusion of the Aorta vs Resuscitative Thoracotomy for Patient Resuscitation After Severe Hemorrhagic Shock – JAMA Surgery (link to abstract – $ for full-text)

 

Delayed QT prolongation: derivation of a novel risk factor for adverse cardiovascular events from acute drug overdose

26 Jan, 2023 | 12:10h | UTC

Delayed QT Prolongation: Derivation of a Novel Risk Factor for Adverse Cardiovascular Events from Acute Drug Overdose – Journal of Medical Toxicology

Commentary: January 2023 Annals of Emergency Medicine Journal Club

 

Cardiogenic Shock | Emergency department-focused management

25 Jan, 2023 | 11:21h | UTC

Cardiogenic Shock: Emergency Department-Focused Management – emDocs

Related: The medical treatment of cardiogenic shock – Journal of Intensive Medicine

 

AHA Statement | Surgical management and mechanical circulatory support in high-risk pulmonary embolisms

24 Jan, 2023 | 14:40h | UTC

Surgical Management and Mechanical Circulatory Support in High-Risk Pulmonary Embolisms: Historical Context, Current Status, and Future Directions: A Scientific Statement From the American Heart Association – Journal of the American Heart Association

News Release: New statement suggests more patients may benefit from surgery for pulmonary embolism – American Heart Association

 

Commentary from one of the authors on Twitter (thread – click for more)

 

RCT | Outcomes not different with early restrictive vs. liberal fluid management in sepsis-induced hypotension

24 Jan, 2023 | 14:38h | UTC

Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Study comparing early interventions for sepsis shows patients have identical outcomes – Vanderbilt University Medical Center

 

Commentary on Twitter

 

Retrospective Study | Serial troponin-T and long-term outcomes in suspected acute coronary syndrome

24 Jan, 2023 | 14:09h | UTC

Serial troponin-T and long-term outcomes in suspected acute coronary syndrome – European Heart Journal

 

Commentary on Twitter

 

Perspective | The top 11 priorities to improve trauma outcomes, from system to patient level

24 Jan, 2023 | 14:06h | UTC

Perspective: the top 11 priorities to improve trauma outcomes, from system to patient level – Critical Care

 

M-A | Mean arterial pressure targets and patient-important outcomes in critically ill adults

23 Jan, 2023 | 13:41h | UTC

Mean Arterial Pressure Targets and Patient-Important Outcomes in Critically Ill Adults: A Systematic Review and Meta-Analysis of Randomized Trials – Critical Care Medicine (free for a limited period)

 

An updated “norepinephrine equivalent” score in intensive care as a marker of shock severity

23 Jan, 2023 | 13:34h | UTC

An updated “norepinephrine equivalent” score in intensive care as a marker of shock severity – Critical Care

 

SR | Mortality as a measure of treatment effect in clinical trials recruiting critically ill patients

23 Jan, 2023 | 13:27h | UTC

Mortality As a Measure of Treatment Effect in Clinical Trials Recruiting Critically Ill Patients – Critical Care Medicine (free for a limited period)

 

Review | Wellens syndrome: an important consideration in patients with chest pain

23 Jan, 2023 | 13:26h | UTC

Wellens syndrome: An important consideration in patients with chest pain – JAAPA

Commentary: Wellens Syndrome Important to Consider if Chest Pain: Key Points – American College of Cardiology

 

AHA Scientific Statement | Diagnosis, workup, risk reduction of transient ischemic attack in the ED setting

20 Jan, 2023 | 14:56h | UTC

Diagnosis, Workup, Risk Reduction of Transient Ischemic Attack in the Emergency Department Setting: A Scientific Statement From the American Heart Association – Stroke

News Release: Stroke symptoms, even if they disappear within an hour, need emergency assessment – American Heart Association

 

Guideline | Diagnosis and treatment of pleural effusion

20 Jan, 2023 | 14:55h | UTC

Diagnosis and Treatment of Pleural Effusion. Recommendations of the Spanish Society of Pulmonology and Thoracic Surgery. Update 2022 – Archivos de Bronconeumología

Related:

Update on Management of Pleural Disease – Current Pulmonology Reports

Pleural Effusion in Adults—Etiology, Diagnosis, and Treatment – Deutsches Ärzteblatt international

Evaluation of the patient with pleural effusion – Canadian Medical Association Journal

State-of-the-art: Radiological investigation of pleural disease – Respiratory Medicine

 

Recommendations for the diagnosis and management of COVID-19 associated bacterial and fungal infections

20 Jan, 2023 | 14:48h | UTC

Recommendations and guidelines for the diagnosis and management of Coronavirus Disease-19 (COVID-19) associated bacterial and fungal infections in Taiwan – Journal of Microbiology, Immunology and Infection

 

Case Report | Catheter-associated superior vena cava syndrome

20 Jan, 2023 | 14:36h | UTC

Catheter-associated superior vena cava syndrome – Canadian Medical Association Journal

 

RCT | Aspirin noninferior to low-molecular-weight heparin for thromboprophylaxis after a fracture

19 Jan, 2023 | 14:30h | UTC

Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Aspirin as effective as blood thinner injections to prevent deadly complications in patients hospitalized with bone fractures – University of Maryland School of Medicine

Commentary: PREVENT CLOT Supports Aspirin for VTE Prevention in Trauma Fractures – TCTMD

 

RCT | No difference in survival with Torsemide vs. Furosemide after discharge of patients hospitalized with heart failure

19 Jan, 2023 | 14:26h | UTC

Effect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart Failure: The TRANSFORM-HF Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: TRANSFORM-HF—Can We Close the Loop on Diuretics in Heart Failure? – JAMA (free for a limited period)

News Release: Comparison of diuretics shows no difference in heart failure survival – NIH/National Heart, Lung and Blood Institute

 

Commentary on Twitter

 

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