Critical Care & Emergencies (all articles)
Randomized Trial: Antipsychotics Ineffective for Delirium in Intensive Care Patients
26 Oct, 2018 | 02:01h | UTCHaloperidol and Ziprasidone for Treatment of Delirium in Critical Illness – New England Journal of Medicine (free for a limited period)
Editorial: Dopamine Antagonists in ICU Delirium (free for a limited period)
Commentaries: Common use of antipsychotics shown ineffective for delirium in intensive care patients – NIH News Releases (free) AND Antipsychotic Drugs Don’t Ease ICU Delirium Or Dementia – NPR (free) AND Antipsychotics ineffective for treating ICU delirium – Vanderbilt University Medical Center (free)
Related Research: Effect of Haloperidol on Survival Among Critically Ill Adults With a High Risk of Delirium (free)
Randomized Trial: Decontamination Strategies and Bloodstream Infections with Antibiotic-Resistant Microorganisms in Ventilated Patients
26 Oct, 2018 | 01:57h | UTCDecontamination Strategies and Bloodstream Infections With Antibiotic-Resistant Microorganisms in Ventilated Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Decontamination of Oral or Digestive Tract for Patients in the Intensive Care Unit (free for a limited period)
“Among patients receiving mechanical ventilation in ICUs with moderate to high ABX resistance prevalence, use of chlorhexidine mouthwash, selective oropharyngeal decontamination, or selective digestive tract decontamination was not associated with reductions in ICU-acquired bloodstream infections caused by MDRGNB vs standard care” (via @JAMA_current see Tweet with visual abstract)
Study: The AI Clinician Learns Optimal Treatment Strategies for Sepsis in Intensive Care
26 Oct, 2018 | 01:56h | UTCThe Artificial Intelligence Clinician learns optimal treatment strategies for sepsis in intensive care – Nature Medicine (free link via Critical Care Reviews)
Commentaries: AI doctor could boost chance of survival for sepsis patients – Imperial College London (free) AND Artificial intelligence system could improve survival for sepsis patients – NHS National Institute for Health Research (free)
Randomized Trial: Protocolized Weaning with Early Extubation to Noninvasive Ventilation vs Invasive Weaning Among Patients Receiving Mechanical Ventilation
26 Oct, 2018 | 01:56h | UTCEffect of Protocolized Weaning with Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure: The Breathe Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Weaning From Mechanical Ventilation: What Should Be Done When a Patient’s Spontaneous Breathing Trial Fails? (free for a limited period)
“Among patients requiring mechanical ventilation in whom a spontaneous breathing trial had failed, early extubation to noninvasive ventilation did not shorten time to liberation from any ventilation.”
Meta-Analysis: Enteral Nutrition Provided Within 48 hours After Admission in Severe Acute Pancreatitis
26 Oct, 2018 | 01:43h | UTC
Review: Enhanced Recovery in Surgical Intensive Care
19 Oct, 2018 | 00:12h | UTCEnhanced Recovery in Surgical Intensive Care: A Review – Frontiers in Medicine (free)
Randomized Trial: Cricoid Pressure vs. Sham Procedure in Elective Intubation
19 Oct, 2018 | 00:11h | UTCEffect of Cricoid Pressure Compared With a Sham Procedure in the Rapid Sequence Induction of Anesthesia: The IRIS Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Commentaries: Is 30 Newtons of Prevention Worth a Pound of a Cure?—Cricoid Pressure – JAMA Surgery (free for a limited period) AND The Case of the Inferior Superiority – EMNerd (free)
Study: Deep Learning Algorithms for Detection of Critical Findings in Head CT Scans
19 Oct, 2018 | 00:08h | UTCDeep learning algorithms for detection of critical findings in head CT scans: a retrospective study – The Lancet (link to abstract – $ for full-text)
Commentary: AI: Deep Learning Algorithms Can Detect Critical Head CT Findings – MedicalResearch.com (free)
Review: Disseminated Intravascular Coagulation
16 Oct, 2018 | 23:37h | UTCSource: Critical Care Reviews Newsletter
Perspective: What Should we Stop Doing in the ICU?
16 Oct, 2018 | 23:36h | UTCWhat should we stop doing in the ICU? – ICU Management & Practice (free)
Review: Treatments Targeting Inotropy
16 Oct, 2018 | 23:37h | UTCTreatments targeting inotropy – European Heart Journal (free)
Current Aspects in Sepsis Approach. Turning Things Around
16 Oct, 2018 | 23:33h | UTCCurrent aspects in sepsis approach. Turning things around – Revista Espanola de Quimioterapia (free)
Source: Critical Care Reviews Newsletter
Review: Demystifying Serotonin Syndrome
16 Oct, 2018 | 23:23h | UTCDemystifying serotonin syndrome (or serotonin toxicity) – Canadian Family Physician (free)
Review: Approach to Oliguria in Critically Ill Patients
16 Oct, 2018 | 23:22h | UTCOliguria in critically ill patients: a narrative review – Journal of Nephrology (free)
Source: Critical Care Reviews Newsletter
How to Prevent Brain-Sapping Delirium in the ICU
12 Oct, 2018 | 01:50h | UTCHow To Prevent Brain-Sapping Delirium In The ICU – NPR (free text and podcast)
Related: ABCDEF Bundle – Society of Critical Care Medicine (free resource) AND The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families – Critical Care Medicine (free)
Evidence-Based Analysis: Venous Thromboembolism Prophylaxis May Cause More Harm than Benefit
12 Oct, 2018 | 01:45h | UTCVenous thromboembolism prophylaxis may cause more harm than benefit: an evidence-based analysis of Canadian and international guidelines – Thrombosis Journal (free) (via @amtejani)
Early vs. Delayed Dialysis in Acute Kidney Injury
11 Oct, 2018 | 21:57h | UTCTiming of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis – New England Journal of Medicine (link to abstract – $ for full-text)
Video Summary: Renal-Replacement Therapy for AKI (free)
Commentary: Is Kidney Dialysis Always Needed When Septic Shock Strikes? – HealthDay (free)
“Trial comparing early vs. delayed strategies of renal-replacement therapy in patients with early-stage septic shock who had severe acute kidney injury finds no significant between-group difference in overall mortality at 90 days.” (via @NEJM see Tweet)
Review: Management of Severe Acute Exacerbations of COPD
11 Oct, 2018 | 21:56h | UTC
Review: Managing the Patient with Heart Failure in the ED
11 Oct, 2018 | 21:45h | UTCManaging the Patient with Heart Failure in the Emergency Department – European Heart Journal (free) (via @gonzaeperez)
Updated German Polytrauma Guideline
11 Oct, 2018 | 21:38h | UTCLevel 3 guideline on the treatment of patients with severe/multiple injuries – German Trauma Society (free)
News Release: The updated German “Polytrauma – Guideline”: an extensive literature evaluation and treatment recommendation for the care of the critically injured patient (free)
Source: Critical Care Reviews Newsletter
ESPEN Guideline on Clinical Nutrition in the Intensive Care Unit
11 Oct, 2018 | 21:37h | UTCESPEN guideline on clinical nutrition in the intensive care unit – Clinical Nutrition (free)
Source: Critical Care Reviews Newsletter
Randomized Trial: Laparoscopic Cholecystectomy vs. Percutaneous Catheter Drainage for Acute Cholecystitis in High Risk Patients
11 Oct, 2018 | 21:32h | UTC“Laparoscopic cholecystectomy compared with percutaneous catheter drainage reduced the rate of major complications in high risk patients with acute cholecystitis.”
COPD Guidelines: A Review of the 2018 GOLD Report
11 Oct, 2018 | 20:07h | UTCCOPD Guidelines: A Review of the 2018 GOLD Report – Mayo Clinic Proceedings (free)
Related: Highlights from the New GOLD COPD Guidelines (free guideline and commentaries)
Two Antiplatelet Drugs may Prevent Further Strokes but Increase Major Bleeds
5 Oct, 2018 | 02:24h | UTCTwo antiplatelet drugs may prevent further strokes but increase major bleeds – NIHR Signal (free)
Original Article: Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA – New England Journal of Medicine (link to abstract – $ for full-text)
Standards for Neurologic Critical Care Units
5 Oct, 2018 | 01:42h | UTC