Critical Care & Emergencies (all articles)
Hemolytic Uremic Syndrome: Diagnosis and Management
23 Oct, 2019 | 07:24h | UTCHaemolytic uremic syndrome: diagnosis and management – F1000Research (free)
Source: Critical Care Reviews Newsletter
Guideline: Management of Nonvariceal Upper Gastrointestinal Bleeding
22 Oct, 2019 | 08:13h | UTCCommentary: Guideline on Managing Acute Upper Gastrointestinal Bleeding Updated – NEJM Journal Watch (free)
Systematic Review: Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD
20 Oct, 2019 | 23:11h | UTCSee also: Full Report (free PDF)
Related: NICE Guideline: Acute Exacerbation of COPD (free)
Cognitive Deficits Following Intensive Care
22 Oct, 2019 | 07:28h | UTCCognitive Deficits Following Intensive Care – Deutsches Ärzteblatt international (free)
Source: Critical Care Reviews Newsletter
Short Review: Prone Positioning in Acute Respiratory Distress Syndrome
14 Oct, 2019 | 08:35h | UTCRelated: Meta-Analysis: Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients with Moderate to Severe Acute Respiratory Distress Syndrome (free meta-analysis and guidelines on the subject) AND Research: ECMO versus Prone Position in ARDS (link to abstract) AND Prone Positioning in Severe Acute Respiratory Distress Syndrome – New England Journal of Medicine (free)
Commentary on the New Pneumonia Guidelines Using GIFs & Some Mini-rants
20 Oct, 2019 | 23:03h | UTCPulmCrit- Commentary on the new pneumonia guidelines using GIFs & some mini-rants (free)
Original Article: ATS/IDSA Guideline: Diagnosis and Treatment of Adults with Community-acquired Pneumonia (free resources)
Review: Management of Blood Pressure in Stroke
18 Oct, 2019 | 08:21h | UTCManagement of blood pressure in stroke – International Journal of Cardiology Hypertension (free)
Related Guidelines: 2018 AHA/ASA Guidelines for the Early Management of Patients With Acute Ischemic Stroke (free) AND AHA/ASA Guidelines for the Management of Spontaneous Intracerebral Hemorrhage (free) AND Canadian Stroke Best Practice Recommendations for Acute Stroke Management (free) AND Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence (free)
Meta-analysis: Early Mobilization of Critically Ill Patients in the Intensive Care Unit
16 Oct, 2019 | 10:28h | UTCRelated: Early Mobilization of Patients in Intensive Care: Organization, Communication and Safety Factors that Influence Translation into Clinical Practice – Critical Care (free) AND Early intervention (mobilization or active exercise) for critically ill adults in the intensive care unit – Cochrane Library (free)
Review: Central Pontine Myelinosis and Osmotic Demyelination Syndrome
16 Oct, 2019 | 10:25h | UTCCentral Pontine Myelinosis and Osmotic Demyelination Syndrome – Deutsches Ärzteblatt international (free)
Source: Critical Care Reviews Newsletter
Case Report: Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock
16 Oct, 2019 | 08:38h | UTCRelated Reviews: Cardiotoxicity of immune checkpoint inhibitors – ESMO Open (free) AND Cardiotoxicity from immune checkpoint inhibitors – IJC Heart & Vasculature (free) AND Cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: A review when cardiology meets immuno-oncology – Journal of the Formosan Medical Association (free)
See also: Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)
Practice-Changing: Tranexamic Acid Reduces the Risk of Head Injury-related Death in Patients with Mild-to-moderate Head Injury
15 Oct, 2019 | 10:56h | UTCCommentaries: CRASH-3: a win for patients with traumatic brain injury – The Lancet (free) AND Global trial is first clear evidence that a widely available drug reduces head injury deaths – London School of Hygiene & Tropical Medicine (free) AND PulmCrit- Tranexamic acid for traumatic brain injury (CRASH3) (free) AND CRASH-3! – Emergency Medicine Literature of Note (free) AND Head injuries: Cheap drug ‘could save thousands of lives a year’ – BBC (free) AND Common drug could prevent thousands of head injury deaths – The Guardian (free)
Related: Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds? (free resources on the subject)
[Abstract Only] Randomized Trial: Similar Outcomes with Conservative Oxygen Therapy vs. Usual Oxygen Therapy During Mechanical Ventilation
15 Oct, 2019 | 10:55h | UTCConservative Oxygen Therapy during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: No clear benefit from conservative oxygen in mechanical ventilation – CHEST Physician (free) AND Trial: No Need for Intensive Oxygen in the ICU – MedPage Today (free registration required)
[Abstract Only] Randomized Trial: Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries
15 Oct, 2019 | 10:14h | UTCOral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: RCT – APAP Only vs APAP-Ibuprofen-Codeine Combo – Journal Feed (free)
“EVALI” (e-cigarette, or vaping, product use-associated lung injury): CDC Updates Guidance and Creates New Name
14 Oct, 2019 | 08:41h | UTCCommentaries: Vaping-related illness has a new name: EVALI – STAT (free) AND No Drop in Vaping Cases, C.D.C. Says – The New York Times (free) AND CDC Updates Guidance on Vaping-Linked Illness, Coins Term EVALI – Medscape (free registration required)
Related: Vaping Illness Update: FDA Warns Public to Stop Using Tetrahydrocannabinol (THC)-Containing Vaping Products and Any Vaping Products Obtained Off the Street – U.S. Food & Drug Administration (free) AND CDC Intensifies Warnings About Vaping Illness As Cases Top 1,000 – NPR (free) AND CDC Report: 76.9% of Patients with Vaping-related Lung Illnesses Used a THC-Containing Product (free) AND Preliminary Report: Pulmonary Illness Related to E-Cigarette Use (free)
Guideline: Management of Severe Asthma Exacerbation
11 Oct, 2019 | 09:47h | UTC
[Abstract Only] Randomized Trial: A Fluid Bolus Does Not Prevent Cardiovascular Collapse Among Critically Ill Adults Undergoing Tracheal Intubation
14 Oct, 2019 | 08:33h | UTCEffect of a fluid bolus on cardiovascular collapse among critically ill adults undergoing tracheal intubation (PrePARE): a randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Source: Critical Care Reviews Newsletter
Related Commentary on Twitter
The PrePARE trial: Fluid bolus
administration did not decrease the overall incidence of
cardiovascular collapse compared with no fluid bolus
administration. Read the article here https://t.co/hNSSsgi6s3 pic.twitter.com/d9iyhAAdUp— The Lancet Respiratory Medicine (@LancetRespirMed) October 3, 2019
Position Statement: Recommendations on the Use of Ultrasound Guidance for Adult Lumbar Puncture
11 Oct, 2019 | 09:35h | UTCEditorial: Ultrasound Guidance for Lumbar Puncture: A Consideration, Not an Obligation (free)
Oxygen Toxicity in Major Emergency Surgery—Anything New?
11 Oct, 2019 | 09:33h | UTCOxygen toxicity in major emergency surgery—anything new? – Intensive Care Medicine (free)
Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND WHO Guidelines for Peri-Operative Hyperoxia Questioned (free) AND The Association Between Supra-Physiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients: A Multi-Centre Observational Cohort Study – American Journal of Respiratory and Critical Care Medicine (free) AND Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit: The Oxygen-ICU Randomized Clinical Trial – JAMA (free)
Review: Ultrasonography of the Lung
10 Oct, 2019 | 09:07h | UTCUltrasonography of the Lung – Rofo (free)
Related: Thoracic Ultrasonography: A Narrative Review (free reviews on the subject)
Review on Transvenous Temporary Pacing Therapy
10 Oct, 2019 | 09:09h | UTCA comprehensive scoping review on transvenous temporary pacing therapy – Netherlands Heart Journal (free)
Source: Critical Care Reviews Newsletter
Consensus Recommendations: Lung-protective Ventilation for the Surgical Patient
8 Oct, 2019 | 10:15h | UTC
Expert Statement on the ICU Management of Thrombotic Thrombocytopenic Purpura
8 Oct, 2019 | 10:09h | UTCRelated Guidelines: Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies – British Journal of Haematology (free) AND Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan – International Journal of Hematology (free) AND Consensus opinion on diagnosis and management of thrombotic microangiopathy in Australia and New Zealand – Nephrology (free)
Podcast: In-Flight Emergencies
8 Oct, 2019 | 10:06h | UTCIn-Flight Emergencies REBOOT with Angelica Zen MD – The Curbsiders Internal Medicine Podcast (free)
Related: In-Flight Medical Emergencies: A Review – JAMA (free)
[Abstract Only] Randomized Trial: Low Dose Azithromycin During Acute COPD Exacerbations Requiring Hospitalization
7 Oct, 2019 | 05:57h | UTCAzithromycin during Acute Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization (BACE). A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentaries: Impact of Azithromycin Studied in Acute Exacerbation of COPD – Physician’s Briefing (free) AND Low-Dose Azithromycin May Improve COPD Exacerbation Outcomes – MedPage Today (free registration required)
Source: EvidenceAlerts
Meta-Analysis: Predictors of Gastrointestinal Bleeding in Adult ICU Patients
7 Oct, 2019 | 05:47h | UTCSource: Grupo UTIclínica – HCFMUSP


