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Critical Care & Emergencies (all articles)

Hemolytic Uremic Syndrome: Diagnosis and Management

23 Oct, 2019 | 07:24h | UTC

Haemolytic uremic syndrome: diagnosis and management – F1000Research (free)

Source: Critical Care Reviews Newsletter

 


Guideline: Management of Nonvariceal Upper Gastrointestinal Bleeding

22 Oct, 2019 | 08:13h | UTC

Management of Nonvariceal Upper Gastrointestinal Bleeding: Guideline Recommendations from the International Consensus Group – Annals of Internal Medicine (free)

Commentary: Guideline on Managing Acute Upper Gastrointestinal Bleeding Updated – NEJM Journal Watch (free)

 


Systematic Review: Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD

20 Oct, 2019 | 23:11h | UTC

Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF)

Related: NICE Guideline: Acute Exacerbation of COPD (free)

 


Cognitive Deficits Following Intensive Care

22 Oct, 2019 | 07:28h | UTC

Cognitive Deficits Following Intensive Care – Deutsches Ärzteblatt international (free)

Source: Critical Care Reviews Newsletter

 


Short Review: Prone Positioning in Acute Respiratory Distress Syndrome

14 Oct, 2019 | 08:35h | UTC

Prone Positioning in Acute Respiratory Distress Syndrome – Seminars in Respiratory and Critical Care Medicine (free)

Related: Meta-Analysis: Assessment of Therapeutic Interventions and Lung Protective Ventilation in Patients with Moderate to Severe Acute Respiratory Distress Syndrome (free meta-analysis and guidelines on the subject) AND Research: ECMO versus Prone Position in ARDS (link to abstract) AND Prone Positioning in Severe Acute Respiratory Distress Syndrome – New England Journal of Medicine (free)

 


Commentary on the New Pneumonia Guidelines Using GIFs & Some Mini-rants

20 Oct, 2019 | 23:03h | UTC

PulmCrit- Commentary on the new pneumonia guidelines using GIFs & some mini-rants (free)

Original Article: ATS/IDSA Guideline: Diagnosis and Treatment of Adults with Community-acquired Pneumonia (free resources)

 


Review: Management of Blood Pressure in Stroke

18 Oct, 2019 | 08:21h | UTC

Management of blood pressure in stroke – International Journal of Cardiology Hypertension (free)

Related Guidelines: 2018 AHA/ASA Guidelines for the Early Management of Patients With Acute Ischemic Stroke (free) AND AHA/ASA Guidelines for the Management of Spontaneous Intracerebral Hemorrhage (free) AND Canadian Stroke Best Practice Recommendations for Acute Stroke Management (free) AND Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence (free)

 


Meta-analysis: Early Mobilization of Critically Ill Patients in the Intensive Care Unit

16 Oct, 2019 | 10:28h | UTC

Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis – PLOS One (free)

Related: Early Mobilization of Patients in Intensive Care: Organization, Communication and Safety Factors that Influence Translation into Clinical Practice – Critical Care (free) AND Early intervention (mobilization or active exercise) for critically ill adults in the intensive care unit – Cochrane Library (free)

 


Review: Central Pontine Myelinosis and Osmotic Demyelination Syndrome

16 Oct, 2019 | 10:25h | UTC

Central Pontine Myelinosis and Osmotic Demyelination Syndrome – Deutsches Ärzteblatt international (free)

Source: Critical Care Reviews Newsletter

 


Case Report: Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock

16 Oct, 2019 | 08:38h | UTC

Immune-Checkpoint Inhibitor-Induced Fulminant Myocarditis and Cardiogenic Shock – JACC: CardioOncology (free)

Related Reviews: Cardiotoxicity of immune checkpoint inhibitors – ESMO Open (free) AND Cardiotoxicity from immune checkpoint inhibitors – IJC Heart & Vasculature (free) AND Cardiovascular toxicity of immune checkpoint inhibitors in cancer patients: A review when cardiology meets immuno-oncology – Journal of the Formosan Medical Association (free)

See also: Related: Immune Checkpoint Inhibitor Toxicities (free guidelines and reviews on the subject)

 


Practice-Changing: Tranexamic Acid Reduces the Risk of Head Injury-related Death in Patients with Mild-to-moderate Head Injury

15 Oct, 2019 | 10:56h | UTC

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial – The Lancet (free)

Commentaries: CRASH-3: a win for patients with traumatic brain injury – The Lancet (free) AND Global trial is first clear evidence that a widely available drug reduces head injury deaths – London School of Hygiene & Tropical Medicine (free) AND PulmCrit- Tranexamic acid for traumatic brain injury (CRASH3) (free) AND CRASH-3! – Emergency Medicine Literature of Note (free) AND Head injuries: Cheap drug ‘could save thousands of lives a year’ – BBC (free) AND Common drug could prevent thousands of head injury deaths – The Guardian (free)

Related: Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds? (free resources on the subject)

 


[Abstract Only] Randomized Trial: Similar Outcomes with Conservative Oxygen Therapy vs. Usual Oxygen Therapy During Mechanical Ventilation

15 Oct, 2019 | 10:55h | UTC

Conservative Oxygen Therapy during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: No clear benefit from conservative oxygen in mechanical ventilation – CHEST Physician (free) AND Trial: No Need for Intensive Oxygen in the ICU – MedPage Today (free registration required)

 


[Abstract Only] Randomized Trial: Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries

15 Oct, 2019 | 10:14h | UTC

Oral Paracetamol Versus Combination Oral Analgesics for Acute Musculoskeletal Injuries – Annals of Emergency Medicine (link to abstract – $ for full-text)

Commentary: RCT – APAP Only vs APAP-Ibuprofen-Codeine Combo – Journal Feed (free)

 


“EVALI” (e-cigarette, or vaping, product use-associated lung injury): CDC Updates Guidance and Creates New Name

14 Oct, 2019 | 08:41h | UTC

Update: Interim Guidance for Health Care Providers Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use Associated Lung Injury — United States, October 2019 – Centers for Disease Control and Prevention (free)

Commentaries: Vaping-related illness has a new name: EVALI – STAT (free) AND No Drop in Vaping Cases, C.D.C. Says – The New York Times (free) AND CDC Updates Guidance on Vaping-Linked Illness, Coins Term EVALI – Medscape (free registration required)

Related: Vaping Illness Update: FDA Warns Public to Stop Using Tetrahydrocannabinol (THC)-Containing Vaping Products and Any Vaping Products Obtained Off the Street – U.S. Food & Drug Administration (free) AND CDC Intensifies Warnings About Vaping Illness As Cases Top 1,000 – NPR (free) AND CDC Report: 76.9% of Patients with Vaping-related Lung Illnesses Used a THC-Containing Product (free) AND Preliminary Report: Pulmonary Illness Related to E-Cigarette Use (free)

 


Guideline: Management of Severe Asthma Exacerbation

11 Oct, 2019 | 09:47h | UTC

Management of severe asthma exacerbation: guidelines from the Société Française de Médecine d’Urgence, the Société de Réanimation de Langue Française and the French Group for Pediatric Intensive Care and Emergencies – Annals of Intensive Care (free)

 


[Abstract Only] Randomized Trial: A Fluid Bolus Does Not Prevent Cardiovascular Collapse Among Critically Ill Adults Undergoing Tracheal Intubation

14 Oct, 2019 | 08:33h | UTC

Effect of a fluid bolus on cardiovascular collapse among critically ill adults undergoing tracheal intubation (PrePARE): a randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Source: Critical Care Reviews Newsletter

 

Related Commentary on Twitter

 


Position Statement: Recommendations on the Use of Ultrasound Guidance for Adult Lumbar Puncture

11 Oct, 2019 | 09:35h | UTC

Recommendations on the Use of Ultrasound Guidance for Adult Lumbar Puncture: A Position Statement of the Society of Hospital Medicine – Journal of Hospital Medicine (free)

Editorial: Ultrasound Guidance for Lumbar Puncture: A Consideration, Not an Obligation (free)

 


Oxygen Toxicity in Major Emergency Surgery—Anything New?

11 Oct, 2019 | 09:33h | UTC

Oxygen toxicity in major emergency surgery—anything new? – Intensive Care Medicine (free)

Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND WHO Guidelines for Peri-Operative Hyperoxia Questioned (free) AND The Association Between Supra-Physiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients: A Multi-Centre Observational Cohort Study – American Journal of Respiratory and Critical Care Medicine (free) AND Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit: The Oxygen-ICU Randomized Clinical Trial – JAMA (free)

 


Review: Ultrasonography of the Lung

10 Oct, 2019 | 09:07h | UTC

Ultrasonography of the Lung – Rofo (free)

Related: Thoracic Ultrasonography: A Narrative Review (free reviews on the subject)

 


Review on Transvenous Temporary Pacing Therapy

10 Oct, 2019 | 09:09h | UTC

A comprehensive scoping review on transvenous temporary pacing therapy – Netherlands Heart Journal (free)

Source: Critical Care Reviews Newsletter

 


Consensus Recommendations: Lung-protective Ventilation for the Surgical Patient

8 Oct, 2019 | 10:15h | UTC

Lung-protective ventilation for the surgical patient: international expert panel-based consensus recommendations – British Journal of Anaesthesia (free)

 


Expert Statement on the ICU Management of Thrombotic Thrombocytopenic Purpura

8 Oct, 2019 | 10:09h | UTC

Expert statement on the ICU management of patients with thrombotic thrombocytopenic purpura – Intensive Care Medicine (free)

Related Guidelines: Guidelines on the diagnosis and management of thrombotic thrombocytopenic purpura and other thrombotic microangiopathies – British Journal of Haematology (free) AND Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan – International Journal of Hematology (free) AND Consensus opinion on diagnosis and management of thrombotic microangiopathy in Australia and New Zealand – Nephrology (free)

 


Podcast: In-Flight Emergencies

8 Oct, 2019 | 10:06h | UTC

In-Flight Emergencies REBOOT with Angelica Zen MD – The Curbsiders Internal Medicine Podcast (free)

Related: In-Flight Medical Emergencies: A Review – JAMA (free)

 


[Abstract Only] Randomized Trial: Low Dose Azithromycin During Acute COPD Exacerbations Requiring Hospitalization

7 Oct, 2019 | 05:57h | UTC

Azithromycin during Acute Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization (BACE). A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)

Commentaries: Impact of Azithromycin Studied in Acute Exacerbation of COPD – Physician’s Briefing (free) AND Low-Dose Azithromycin May Improve COPD Exacerbation Outcomes – MedPage Today (free registration required)

Source: EvidenceAlerts

 


Meta-Analysis: Predictors of Gastrointestinal Bleeding in Adult ICU Patients

7 Oct, 2019 | 05:47h | UTC

Predictors of gastrointestinal bleeding in adult ICU patients: a systematic review and meta-analysis – Intensive Care Medicine (free)

Related: Stress ulcer prophylaxis with proton pump inhibitors or histamin-2 receptor antagonists in adult intensive care patients: a systematic review with meta-analysis and trial sequential analysis – Intensive Care Medicine (free)

Source: Grupo UTIclínica – HCFMUSP

 


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