Critical Care & Emergencies (all articles)
[Abstract Only] Study: Evidence of Bacterial Transmission from Probiotic Capsule to Blood in ICU Patients
8 Nov, 2019 | 07:36h | UTCGenomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients – Nature Medicine (link to abstract – $ for full-text)
Related: Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries) AND The Problem With Probiotics – The New York Times (free)
Related Commentary on Twitter
The use of #probiotics in hospitals is increasing. Now the first proof via genomic sequencing that these pills can induce sepsis https://t.co/mY0gxPXFQ1 @NatureMedicine by @TechnionLive's @idanyelin @harvardmed and collaborators pic.twitter.com/GZ6HgwxWyR
— Eric Topol (@EricTopol) November 7, 2019
Guidelines for the Prevention and Treatment of Acute Altitude Illness
6 Nov, 2019 | 08:41h | UTCRelated: Interventions for treating acute high altitude illness – Cochrane Library (free) AND Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs – Cochrane Library (free) AND Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs – Cochrane Library (free) AND Interventions for preventing high altitude illness: Part 3. Miscellaneous and non‐pharmacological interventions – Cochrane Library (free) AND Acute high-altitude sickness – European Respiratory Review (free) AND High-altitude illness: Management approach – Turkish Journal of Emergency Medicine (free)
[Abstract Only] Randomized Trial: Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest
7 Nov, 2019 | 08:24h | UTCPrevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Routine Antibiotics Help Ventilated Patients After Cardiac Arrest – MedPage Today (free registration required)
Ten Things ICU Specialists Need to Know About New Valvular Procedures in Interventional Cardiology
7 Nov, 2019 | 08:11h | UTC
State of the Art Review: Vasopressor Therapy in Critically Ill Patients with Shock
7 Nov, 2019 | 08:09h | UTCVasopressor therapy in critically ill patients with shock – Intensive Care Medicine (free)
Related: Editorial: Focus on Blood Pressure Targets and Vasopressors in Critically Ill Patients (free editorial and reviews)
[Abstract Only] Another Study Questions the Association of Contrast Use and Acute Kidney Injury
7 Nov, 2019 | 08:03h | UTCAssociation of contrast and acute kidney injury in the critically ill: A propensity matched study – CHEST (link to abstract – $ for full-text)
Commentary: No association between contrast use and AKI seen in critically ill patients with normal kidney function – ACP Hospitalist (free)
Related: Does contrast cause kidney injury? The evidence – First10EM (free) AND Are the Risks Of Drugs That Enhance Imaging Tests Overblown? – NPR (free) AND Acute Kidney Injury After Computed Tomography: A Meta-analysis – Annals of Emergency Medicine (link to abstract – $ for full-text) AND Risk of Acute Kidney Injury After Intravenous Contrast Media Administration – Annals of Emergency Medicine (link to abstract – $ for full-text) AND
Guidelines for the Treatment and Prevention of Drowning
6 Nov, 2019 | 08:43h | UTCRelated Guidelines: Prevention of Drowning – American Academy of Pediatrics (free) AND Preventing drowning: an implementation guide – World Health Organization (free PDF) AND Global report on drowning: preventing a leading killer – World Health Organization (free PDF) Report: Open Water Drowning and Risks for Children (free)
Guidelines for the Prevention and Treatment of Heat Illness
6 Nov, 2019 | 08:39h | UTCRelated: National Athletic Trainers’ Association Position Statement: Exertional Heat Illnesses (free) AND Heat stroke – Journal of Intensive Care (free)
[Abstract Only] Study: Early Palliative Care Consultation May Positively Impact the Care of High Risk, Critically Ill Patients
6 Nov, 2019 | 08:31h | UTCEarly Palliative Care Consultation in the Medical ICU: A Cluster Randomized Crossover Trial – Critical Care Medicine (link to abstract – $ for full-text)
Source: EvidenceAlerts
Related Commentary on Twitter
Breaking @CritCareMed: High-quality RCT in 2 MICUs. Early triggered palliative consult -> more DNRs, more hospice use, fewer MV days & lower ICU cost, all w/o compromising LOS/mortality. https://t.co/kQpTcEgwwM
— Jonathan Yeh MD (@JonathanYehMD) October 15, 2019
Podcast: Random Pearls in Pulmonary Medicine and Critical Care from #CHEST2019 in New Orleans
5 Nov, 2019 | 08:39h | UTC#179 CHEST 2019 Recap Part 1 – The Curbsiders Internal Medicine Podcast (free audio)
#180 CHEST 2019 Recap Part 2 from New Orleans – The Curbsiders Internal Medicine Podcast (free audio)
Systematic Review: Intra‐pleural Fibrinolytic Therapy for the Treatment of Parapneumonic Effusions and Empyema
31 Oct, 2019 | 08:18h | UTCIntra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult parapneumonic effusions and empyema – Cochrane Library (free)
Summary: Clot-busting drugs for infections of the lining of the lung – Cochrane Library (free)
[Abstract Only] Randomized Trial: Therapeutic-induced Hypertension May Improve Outcomes in Selected Patients with Noncardioembolic Acute Stroke
4 Nov, 2019 | 01:10h | UTCTherapeutic-induced hypertension in patients with noncardioembolic acute stroke – Neurology (link to abstract – $ for full-text)
Related Commentary on Twitter
Provocative paper in @GreenJournal providing class III evidence for therapeutic-induced hypertension in patients with noncardioembolic acute stroke. Those randomized to phenylephrine-induced SBP of 200mmHg had early neurologic improvement and a higher rate of mRS 0-2 at 90days. https://t.co/LH6NyqTDYe
— Neurohospitalist Society (@Neurohosp) October 24, 2019
Podcast: Emerging Applications for Ketamine
4 Nov, 2019 | 00:50h | UTCEmerging Applications for Ketamine – JAMA (free audio)
Related Resources:
Ketamine for Depression: Ketamine and depression: a narrative review – Drug Design, Development and Therapy (free)
Meta-Analysis: Short- vs. Long-term Dual Antiplatelet Therapy in Secondary Prevention for Ischemic Stroke
1 Nov, 2019 | 10:24h | UTCRelated Study: Dual Antiplatelet Therapy Should be Used for 21 Days After Minor Ischemic Stroke or High-risk Transient Ischemic Attack (link to abstract)
Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)
Related Commentary on Twitter
Short-term DAPT had better risk-benefit profile than long-term DAPT in secondary prevention of ischaemic stroke – a network meta-analysis https://t.co/suoThL5GLK@escardio #EHJQCCO @adamtimmis @cpgale3 #cardiotwitter pic.twitter.com/ppzyv37Oou
— European Society of Cardiology Journals (@ESC_Journals) October 27, 2019
Systematic Review: Early Enteral Nutrition vs. Delayed Enteral Nutrition, With or Without Supplemental Parenteral Nutrition in Critically Ill Adults
1 Nov, 2019 | 07:45h | UTCEarly enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without supplemental parenteral nutrition in critically ill adults – Cochrane Library (free)
AHA/ASA Guideline Update: Early Management of Acute Ischemic Stroke
31 Oct, 2019 | 08:49h | UTCTop Things to Know: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke (free)
Consensus Statement: A Management Algorithm for Patients with Intracranial Pressure Monitoring
31 Oct, 2019 | 08:48h | UTC
Related Commentary on Twitter
A management algorithm for patients with intracranial pressure monitoring.
A useful resource for everyone interested in traumatic brain injury worldwide…free access at https://t.co/PHjX73Rto9
A "must read" pic.twitter.com/vMoq1ZZgaO— Intensive Care Medicine (@yourICM) October 29, 2019
Together We Stand, Divided We Fall: A Multidisciplinary Approach in Complicated Acute Pancreatitis
30 Oct, 2019 | 07:46h | UTCRelated Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
Opinion – “Sepsis Hysteria: Excess Hype and Unrealistic Expectations”
27 Oct, 2019 | 23:49h | UTCSepsis hysteria: excess hype and unrealistic expectations – The Lancet (free)
Commentary: Sepsis myths create ‘unhealthy climate of fear’, say experts – The Guardian (free)
Source: Grupo UTIclínica – HCFMUSP
Related Commentary on Twitter
"It is crucial to expose the fictions surrounding #sepsis…to create realistic expectations about outcomes"
Sepsis hysteria: NEW Correspondence from M Singer, M Inada-Kim & M Shankar-Hari https://t.co/3oVYkE1BQS pic.twitter.com/gMvdVyCicc
— The Lancet (@TheLancet) October 25, 2019
Diagnosis and Management of Disorders of Body Tonicity—Hyponatremia and Hypernatremia
28 Oct, 2019 | 00:46h | UTCSource: Grupo UTIclínica – HCFMUSP
Things We Do for No Reason: Supplemental Oxygen for Patients without Hypoxemia
27 Oct, 2019 | 23:40h | UTCSee other articles in the series: Choosing Wisely: Things We Do For No Reason (free)
Related: Oxygen therapy for acutely ill medical patients: a clinical practice guideline – The BMJ (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free)
Hospital Medicine Update: High-Impact Literature from March 2018 to April 2019
27 Oct, 2019 | 23:42h | UTC
Study Suggests Methicillin-Resistant Staphylococcus Aureus (MRSA) Acquisition and Infections are Not Impacted by use of Active Surveillance and Contact Precautions
24 Oct, 2019 | 08:14h | UTCThe effectiveness of Contact Precautions on methicillin-resistant Staphylococcus aureus (MRSA) in long-term care across the United States – Clinical Infectious Diseases (free for a limited period)
Commentary: VA study finds contact precautions don’t affect MRSA in long-term care – CIDRAP (free)
[Abstract Only] Cardiogenic Shock Classification Predicts Mortality in the Cardiac Intensive Care Unit
23 Oct, 2019 | 08:21h | UTCCardiogenic Shock Classification to Predict Mortality in the Cardiac Intensive Care Unit – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: SCAI Shock Definition Tracks Well With Mortality in Cardiac ICU – TCTMD (free) AND Shock Classification Stratifies Mortality Risk – American College of Cardiology (free) AND SCAI’s new shock classification scheme used to analyze patients in cardiac intensive care unit – News Medical (free)
Commentary: Do Fluid Boluses Before Intubation Help? (PREPARE trial)
23 Oct, 2019 | 08:15h | UTCDo fluid boluses before intubation help? (PREPARE trial) – PulmCrit (free)
Original Study: Randomized Trial: A Fluid Bolus Does Not Prevent Cardiovascular Collapse Among Critically Ill Adults Undergoing Tracheal Intubation (link to abstract – $ for full-text)