Critical Care & Emergencies (all articles)
Refeeding Syndrome in the Critically Ill: a Literature Review and Clinician’s Guide
27 Nov, 2019 | 08:03h | UTC
Meta-Analysis: Comparing the Effects of Giving Perioperative Oxygen Therapy of 30% FiO2 to 80% FiO2 on Surgical Site Infection and Mortality
27 Nov, 2019 | 08:04h | UTCRelated: WHO Guidelines for Peri-Operative Hyperoxia Questioned (free)
Source: EvidenceAlerts
KDIGO Controversies Conference: Potassium Homeostasis and Management of Dyskalemia in Kidney Diseases
24 Nov, 2019 | 21:07h | UTCRelated: Physiology and Pathophysiology of Potassium Homeostasis: Core Curriculum 2019 – American Journal of Kidney Diseases (free)
Perspective: Toward Increased Understanding of the Steroid Controversy in Septic Shock
22 Nov, 2019 | 08:35h | UTCToward Increased Understanding of the Steroid Controversy in Septic Shock – Critical Care Medicine (free)
See also: Why Understanding Sepsis Endotypes Is Important for Steroid Trials in Septic Shock (free) AND Why the Adjunctive Corticosteroid Treatment in Critically Ill Patients With Septic Shock (ADRENAL) Trial Did Not Show a Difference in Mortality (free) AND Why My Steroid Trials in Septic Shock Were “Positive” (free)
Related: Review: Adjunctive Corticosteroid Treatment in Septic Shock (free review, guideline, and meta-analysis on the subject)
Related Commentary on Twitter
Caught up in steroid controversy in septic shock? Read 3 viewpoints in #CritCareMed from investigators of ADRENAL, APROCCHSS & VANISH trials.
Russell et al: Toward Increased Understanding of Steroid Controversy in Septic Shock
Link: https://t.co/Is5laK5DXR@SCCM #Sepsis pic.twitter.com/v8TbxuAi93— Critical Care Medicine (@CritCareMed) November 21, 2019
Study: A Digital Sepsis Alert is Associated with Improved Outcomes, Including Timely Antibiotics
22 Nov, 2019 | 08:33h | UTCCommentary: Digital monitoring system helps improve hospital care of sepsis patients – OnMedica (free) AND Sepsis digital alert ‘led to faster treatment with antibiotics’ – BBC (free)
Related Commentary on Twitter
Such a simple intervention! A digital #sepsis alert system implemented across 3 london hospitals was associated with a 24% lower odds of death, shorter hospital stay & more timely #antibiotic administration. https://t.co/tvgR2cdZ7x
— Shamez Ladhani (@ShamezLadhani) November 21, 2019
Review: Nutrition Therapy and Critical Illness
22 Nov, 2019 | 08:31h | UTCRelated: ESPEN guideline on clinical nutrition in the intensive care unit – Clinical Nutrition (free) AND Special Issue: Nutrition in Critical Illness – ICU Management & Practice (free)
[Abstract Only] Meta-Analysis: Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure
22 Nov, 2019 | 08:23h | UTCBedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Bedside optic nerve ultrasonography may be useful for measuring intracranial pressure – ACP Hospitalist (free) AND Optic Nerve Ultrasound May ID Increased Intracranial Pressure – Physician’s Briefing (free)
Related Commentary on Twitter
Researchers from @McMasterU found bedside optic nerve ultrasound holds promise for diagnosing increased intracranial pressure in children and adults https://t.co/6Kx40JQuG1. pic.twitter.com/xECX6eyq1s
— Annals of Int Med (@AnnalsofIM) November 19, 2019
Meta-Analysis: Association of Nutritional Support with Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk
21 Nov, 2019 | 08:35h | UTCCommentaries: Nutritional Support Among Medical Inpatients—Feed the Cold (and Malnourished) and Starve the Febrile – JAMA Network Open (free) AND Nutritional Support Linked to Better Survival Among Inpatients – Medscape (free registration required)
[Abstract Only] Meta-Analysis: Return to Work After Critical Illness
21 Nov, 2019 | 08:02h | UTCReturn to work after critical illness: a systematic review and meta-analysis – Thorax (link to abstract – $ for full-text)
Commentary: ICU survivors commonly experience job loss after critical illness, study confirms – University of California San Diego School of Medicine (free)
Systematic Review: Safety of Peripheral Administration of Vasopressor Medications
21 Nov, 2019 | 08:08h | UTC
Review: Extra-cardiac Endovascular Infections in the Critically Ill
20 Nov, 2019 | 10:22h | UTCExtra-cardiac endovascular infections in the critically ill – Intensive Care Medicine (free)
Guidelines for Awake Tracheal Intubation in Adults
19 Nov, 2019 | 09:59h | UTCDifficult Airway Society guidelines for awake tracheal intubation (ATI) in adults – Anaesthesia (free)
Related Commentary on Twitter
🔐Published today and #FOAMed! The new @dasairway awake tracheal intubation guidelines are about to be presented at @WAMM_2019 ! @dr_imranahmad @elboghdadly @altgm @ravibhagrath @ProfEllenO @oldandbaffled @WAMM_2019 #DASATI
🔗https://t.co/uwqILqCfeD pic.twitter.com/1HBUoGntzj
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) November 15, 2019
#AHA19 – [Abstract Only] Practice Changing? – Randomized Trial: Low-Dose Colchicine Improves Outcomes after Myocardial Infarction
18 Nov, 2019 | 01:11h | UTCEfficacy and Safety of Low-Dose Colchicine after Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Colchicine Cardiovascular Outcomes Trial – COLCOT – American College of Cardiology (free) AND COLCOT Renews Hope for Anti-inflammatory in Secondary Prevention: Colchicine – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
In a randomized, placebo-controlled trial of 4745 patients with recent myocardial infarction, low-dose colchicine (0.5 mg once daily) prevented ischemic cardiovascular events. See the COLCOT trial. #AHA19 https://t.co/H2eubZ6HRD
— NEJM (@NEJM) November 16, 2019
AHA Updates on Advanced Cardiovascular Life Support (ACLS)
18 Nov, 2019 | 01:00h | UTC– 2019 American Heart Association and American Red Cross Focused Update for First Aid: Presyncope – Circulation (free PDF)
Summary of Recommendations: International Consensus on CPR and Emergency Cardiovascular Care for Children and Adults
18 Nov, 2019 | 00:52h | UTC
Intensivist Burnout: Running on Empty?
18 Nov, 2019 | 00:26h | UTCIntensivist Burnout: Running on Empty? – CHEST (free)
Review: Post-operative Abdominal Infections: Epidemiology, Operational Definitions, and Outcomes
15 Nov, 2019 | 10:14h | UTCRelated Guidelines: The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines – World Journal of Emergency Surgery (free) AND Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference – World Journal of Emergency Surgery (free) AND The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections (free) AND The 2018 Lebanese Society of Infectious Diseases and Clinical Microbiology Guidelines for the use of antimicrobial therapy in complicated intra-abdominal infections in the era of antimicrobial resistance – BMC Infectious Diseases (free)
Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache
13 Nov, 2019 | 10:47h | UTC
[Abstract Only] Small Randomized Trial Suggests an Initial Imaging-Guided Strategy May Reduce Invasive Coronary Angiograms in Patients with Non–ST-Segment Elevation Myocardial Infarction and Inconclusive ECGs
13 Nov, 2019 | 10:43h | UTCInitial Imaging-Guided Strategy Versus Routine Care in Patients with Non–ST-Segment Elevation Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Upfront Imaging Reduces Invasive Angiography in Patients With Unclear NSTEMI Diagnosis – TCTMD (free) AND Imaging-Guided Strategy vs. Routine Care for NSTEMI Patients – American College of Cardiology (free)
Randomized Trial: 0/1-hour High-sensitivity Cardiac Troponin T Protocol Enables Faster Discharge of Patients with Suspected Acute Coronary Syndrome
12 Nov, 2019 | 11:20h | UTCA Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes – Circulation (free for a limited period)
Commentaries: World-First Trial Cuts ED Wait Times and Admissions – Flinders University (free) AND Ruling Out MI Safe With 0/1-Hour High-Sensitivity Troponin: RAPID-TNT – TCTMD (free)
Related Studies/Commentaries Highlighting Problems with High-sensitivity Cardiac Troponin: Myths in Emergency Medicine: Is hs-cTnT Worth the Downstream Testing? – Emergency Medicine News (free) AND Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome – The Lancet (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival – Journal of the American College of Cardiology (free) AND Cohort Study: High Sensitivity Cardiac Troponin May Result in Misdiagnosis of Acute Myocardial Infarction – The BMJ (free)
FDA Safety Communication: Biotin Supplements May Result in Falsely Low Troponin Results
10 Nov, 2019 | 13:43h | UTCCommentary: FDA Updates Warning on Biotin Interfering with Lab Results – NEJM Journal Watch (free)
“…the FDA is particularly concerned about biotin interference causing a falsely low result for troponin, a clinically important biomarker to aid in the diagnosis of heart attacks, which may lead to a missed diagnosis and potentially serious clinical implications. The FDA continues to receive adverse events reports indicating biotin interference caused falsely low troponin results.”
Study Commentary: Can C-reactive Protein Improve Treatment for COPD Exacerbations?
10 Nov, 2019 | 13:25h | UTCCan C-reactive protein improve treatment for COPD exacerbations? – PulmCCM (free)
Original Study: Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations (link to abstract and commentaries)
Meta-Analysis: Effect of Lung Recruitment Maneuver on Oxygenation, Physiological Parameters and Mortality in ARDS Patients
8 Nov, 2019 | 08:00h | UTCRelated: Alveolar recruitment in acute respiratory distress syndrome: should we open the lung (no matter what) or may accept (part of) the lung closed? – Intensive Care Medicine (free) AND Recruitment maneuver does not provide any mortality benefit over lung protective strategy ventilation in adult patients with acute respiratory distress syndrome: a meta-analysis and systematic review of the randomized controlled trials – Journal of Intensive Care (free) AND Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial – JAMA (free study and editorial)
[Abstract Only] Randomized Trial Suggests Possible Harm from Perioperative Probiotics Among Patients Undergoing Major Abdominal Operation
8 Nov, 2019 | 07:49h | UTCRandomized Trial of Perioperative Probiotics Among Patients Undergoing Major Abdominal Operation – Journal of the American College of Surgeons (link to abstract – $ for full-text)
Source: EvidenceAlerts
“A significantly higher readmission rate was observed among those exposed to probiotics. Additional studies remain warranted.”
Systematic Review: Strategies to Reduce Non-ventilator-associated Hospital-acquired Pneumonia
8 Nov, 2019 | 08:14h | UTC