Critical Care & Emergencies (all articles)
Podcast: Managing acute pancreatitis
26 Aug, 2020 | 03:51h | UTCManaging Acute Pancreatitis – JAMA
First Covid-19 reinfection documented in Hong Kong
25 Aug, 2020 | 04:00h | UTCFirst Covid-19 reinfection documented in Hong Kong, researchers say – STAT
Commentaries: Some people can get the pandemic virus twice, a study suggests. That is no reason to panic – Science AND You can get reinfected with Covid-19 but still have immunity. Let’s explain – Vox AND Expert reaction to first reported case of COVID-19 re-infection in Hong Kong patient – Science Media Centre
Commentary on Twitter
In Hong Kong, researchers reported what appears to be the first confirmed case of Covid-19 reinfection in a 33-year-old man. The virus sequenced from his two infections didn't match, indicating the second one was not tied to the first. https://t.co/4GHd1lMRZ0
— STAT (@statnews) August 24, 2020
FDA issues emergency use authorization for convalescent plasma as potential COVID–19 treatment
25 Aug, 2020 | 03:58h | UTCCommentaries: Convalescent Plasma: The Science and the Politics – Science Translational Medicine AND Convalescent plasma: another controversial clash of politics & science – Health News Review AND Observational Study of Convalescent Plasma and FDA Response – datamethods AND FDA OKs use of convalescent plasma for COVID-1 – CIDRAP AND Is convalescent plasma safe and effective? We answer the major questions about the Covid-19 treatment – STAT
Anticipating and managing coagulopathy and thrombotic manifestations of severe COVID-19
25 Aug, 2020 | 03:53h | UTC
An inflammatory cytokine signature predicts COVID-19 severity and survival
25 Aug, 2020 | 03:57h | UTCAn inflammatory cytokine signature predicts COVID-19 severity and survival – Nature
Commentary: Researchers discover immune predictors of COVID-19 cases that fare the worst – The Mount Sinai Hospital
Commentary on Twitter
Elevated levels of serum IL-6 and TNF-α at the time of hospitalization are independent and significant predictors of clinical outcome in two cohorts of patients with #COVID19 #biomarker @IcahnMountSinai @SinaiImmunol @TischCancer @MiriamMerad https://t.co/syHWT6QaW0
— Nature Medicine (@NatureMedicine) August 24, 2020
Meta-analysis: Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients
25 Aug, 2020 | 03:40h | UTC
Podcast: Hypertension in the Hospital
25 Aug, 2020 | 03:38h | UTCAnnals On Call – Hypertension in the Hospital – Annals of Internal Medicine
Commentary on Twitter
Listen to the latest #AnnalsOnCall with @medrants, Dr Timothy Anderson, and @WrayCharles on #Hypertension in the Hospital https://t.co/OouHuYg0wt. pic.twitter.com/CbJyq7wyDq
— Annals of Int Med (@AnnalsofIM) August 24, 2020
Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients
25 Aug, 2020 | 03:45h | UTC
Observational study: Revascularization practices and outcomes in patients with multivessel coronary artery disease who presented with acute myocardial infarction and cardiogenic shock
25 Aug, 2020 | 03:42h | UTCRevascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018 – JAMA Internal Medicine (free for a limited period)
Editorial: Multivessel or Culprit Vessel–Only Percutaneous Coronary Intervention for Patients With Acute Myocardial Infarction and Cardiogenic Shock: Real-World Evidence in Support of CULPRIT-SHOCK (free for a limited period)
Commentaries: Multivessel PCI Associated With Higher In-Hospital Mortality Compared With Culprit-Vessel PCI, NCDR Study Finds – American College of Cardiology AND Less aggressive treatment better for heart patients who go into shock – Yale University
Related Research: PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock – New England Journal of Medicine AND One-Year Outcomes after PCI Strategies in Cardiogenic Shock – New England Journal of Medicine
Commentary on Twitter (Thread – Click for more)
In @JAMAInternalMed is our evaluation of revascularization practices in AMI w shock
In 2017, CULPRIT-SHOCK found harm w MV-PCI in MV-CAD – in the decade preceding it, MV-PCI was an increasingly popular strategy.
🧵below
w/ @rwyeh @ACCinTouch https://t.co/xz0HHnvhNU pic.twitter.com/DWaVXG8vcU
— Rohan Khera (@rohan_khera) August 24, 2020
The neuroleptic malignant syndrome—a systematic case series analysis focusing on therapy regimes and outcome
25 Aug, 2020 | 03:37h | UTCCommentary: Treating Neuroleptic Malignant Syndrome: A Case Series – NEJM Journal Watch
Randomized trial: Remdesivir vs. standard care in patients with moderate COVID-19
24 Aug, 2020 | 00:53h | UTCEditorial: Efficacy of Remdesivir in COVID-19
Commentaries: Study: Remdesivir doesn’t boost outcomes in moderate pneumonia from COVID-19 – UPI AND New Remdesivir Study Shows the Trouble With Bad Science – The Wire
Commentary on Twitter
Remdesivir….good editorial, concludes we don't know who to give it to, nor for how long, nor if it improves outcomes, nor whether, if it does, it does that beyond what dexamethasone or other corticosteroids do. https://t.co/Qi1dTSPcYi
— Dr. Tom Frieden (@DrTomFrieden) August 21, 2020
COVID-19: Interim guidance on rehabilitation in the hospital and post-hospital phase
24 Aug, 2020 | 00:54h | UTC
Review: The interpretation of SARS-CoV-2 diagnostic tests
24 Aug, 2020 | 00:40h | UTCThe Interpretation of SARS-CoV-2 Diagnostic Tests – Med
Recurrence or relapse of COVID‐19 in older patients: A description of three cases
24 Aug, 2020 | 00:42h | UTC
Neuroradiologic manifestations of COVID-19: What the emergency radiologist needs to know
24 Aug, 2020 | 00:32h | UTC
Dexamethasone and hydroxychloroquine: Why randomized controlled trials matter
21 Aug, 2020 | 02:37h | UTC
Evidence lags behind excitement over blood plasma as a coronavirus treatment
21 Aug, 2020 | 02:36h | UTCEvidence lags behind excitement over blood plasma as a coronavirus treatment – Nature
Histopathological findings and viral tropism in patients with severe fatal COVID-19: A post-mortem study
21 Aug, 2020 | 02:31h | UTCCommentary: Blood clots and lung injuries found in patients who have died of COVID-19 – Imperial College London
COVID-19 and cardiac arrhythmias
21 Aug, 2020 | 02:29h | UTCCOVID-19 Infection and Cardiac Arrhythmias – Trends in Cardiovascular Medicine
Management and outcomes of patients with STEMI during the COVID-19 pandemic in China
21 Aug, 2020 | 02:28h | UTC
Systematic review: Multiple vs. fewer antiplatelet agents for preventing early recurrence after ischemic stroke or transient ischemic attack
21 Aug, 2020 | 02:25h | UTC
Non-cardiac surgery in patients with coronary artery disease: Risk evaluation and periprocedural management
21 Aug, 2020 | 02:23h | UTC
Review: Effects of COVID-19 on the nervous system
20 Aug, 2020 | 09:39h | UTCEffects of COVID-19 on the nervous system – Cell
NICE Guideline: Perioperative care in adults
20 Aug, 2020 | 09:17h | UTCPerioperative care in adults – National Institute for Health and Care Excellence
Commentary on Twitter
https://t.co/1aHU3TroSp
NICE published its periop care guidelines today. Rather than being a compendium of periop medicine, it provides guidance on how the care can be improved, and should be welcomed by all periop HCPs pic.twitter.com/qlPifdUZll— Nicholas Levy (@nicholasalevy) August 19, 2020
Another randomized trial shows no benefit from ascorbic acid, corticosteroids, and thiamine in septic shock
19 Aug, 2020 | 09:28h | UTCEffect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
In this RCT, a combination of hydrocortisone, ascorbic acid, and thiamine (the HAT or Marik protocol) did not statistically significantly reduce SOFA score or mortality within 72 hours of enrollment among patients with septic shock https://t.co/cuB6X4fJhi
— JAMA (@JAMA_current) August 18, 2020