Critical Care & Emergencies (all articles)
COVID-19 and cardiovascular disease: From basic mechanisms to clinical perspectives
27 Jul, 2020 | 10:01h | UTC
Coalition Covid-19 Brazil – Randomized trial: hydroxychloroquine with or without azithromycin in mild-to-moderate Covid-19
24 Jul, 2020 | 09:37h | UTCCommentary: Another study finds hydroxychloroquine does not help Covid-19 patients – CNN
Meta-analysis: Bacterial co-infection and secondary infection in patients with COVID-19
24 Jul, 2020 | 09:26h | UTC
Audio interview: Dexamethasone and Covid-19
23 Jul, 2020 | 08:44h | UTCAudio Interview: Dexamethasone and Covid-19 – New England Journal of Medicine
Observational study: Glucocorticoid treatment linked to reduced mortality in patients with Covid-19 and initial C-reactive protein ≥20 mg/dL
23 Jul, 2020 | 08:49h | UTCCommentaries: A blood test may show which COVID-19 patients steroids will help — or harm – Science News AND Common blood test identifies benefits and risks of steroid treatment in COVID-19 patients – Albert Einstein College of Medicine
Fasting blood glucose at admission as a predictor for mortality in patients with COVID-19 without previous diagnosis of diabetes
23 Jul, 2020 | 08:28h | UTCCommentaries: Study links abnormally high blood sugar with higher risk of death in COVID-19 patients not previously diagnosed with diabetes – Diabetologia AND Expert reaction to study looking at blood sugar level and death in hospitalised COVID-19 patients in Wuhan – Science Media Centre
Chest CT in COVID-19 pneumonia: A review of current knowledge
23 Jul, 2020 | 08:27h | UTC
Management and prevention of anemia (acute bleeding excluded) in adult critical care patients
23 Jul, 2020 | 08:21h | UTC
[Press release-based medicine…] Synairgen announces positive results from trial of SNG001 in hospitalized COVID-19 patients
21 Jul, 2020 | 09:27h | UTCSynairgen announces positive results from trial of SNG001 in hospitalised COVID-19 patients
Commentaries: New Treatment for Covid-19 Shows Promise, but Scientists Urge Caution – The New York Times AND Expert reaction to announcement by Synairgen that their drug SNG001 has had positive results in initial trials on COVID-19 patients – Science Media Centre AND Trial of Covid-19 drug given via inhaler ‘very promising’, say scientists – The Guardian
Survivorship after COVID-19 ICU stay
21 Jul, 2020 | 09:23h | UTCSurvivorship after COVID-19 ICU stay – Nature Reviews
[Preprint] Covid-19: Six clusters of symptoms could be used as a clinical prediction tool
21 Jul, 2020 | 09:25h | UTCCommentaries: Covid-19: Study reveals six clusters of symptoms that could be used as a clinical prediction tool – The BMJ AND Six distinct ‘types’ of COVID-19 identified – King’s College London AND Coronavirus symptoms fall into six different groupings, study finds – The Guardian
[Abstract Only] Randomized trial: Dexmedetomidine does not decrease postoperative atrial arrhythmias or delirium in patients recovering from cardiac surgery
21 Jul, 2020 | 09:16h | UTC
Related Commentary on Twitter
DECADE: in 794 cardiac surgery patients, dexmedetomidine vs saline from surgical incision till 24h led to less atrial fibrillation (30% vs 34%, n.s.), but more delirium (17% vs 12%, n.s.), and more serious events (5% vs 1% ns).
Thanks to @CritCareReviews https://t.co/ZGs1ZSGMmP— Peter Nydahl (@NydahlPeter) July 20, 2020
Guideline: Diagnosing acute aortic syndrome
21 Jul, 2020 | 09:18h | UTCCommentary: New guideline can help clinicians identify hard-to-diagnose acute aortic syndrome – News Medical
Podcast on acute kidney injury: myths & musings
21 Jul, 2020 | 08:59h | UTC#226 Kidney Boy on Acute Kidney Injury: Myths & Musings – The Curbsiders Internal Medicine Podcast
Randomized trial: dexamethasone in hospitalized patients with Covid-19
20 Jul, 2020 | 08:18h | UTCCommentary: Trial data support dexamethasone, but not hydroxychloroquine, for COVID-19 – CIDRAP
Related Commentary on Twitter
A randomized controlled trial testing dexamethasone for Covid-19 (the RECOVERY trial) showed that, compared with usual care, this corticosteroid drug reduced 28-day mortality in hospitalized patients. #COVID19 #SARSCoV2
— NEJM (@NEJM) July 18, 2020
The role of chest radiography in confirming Covid-19 pneumonia
20 Jul, 2020 | 08:13h | UTCThe role of chest radiography in confirming covid-19 pneumonia – The BMJ
Related Commentary on Twitter
"No single feature of covid-19 pneumonia on a chest radiograph is specific or diagnostic, but a combination of multifocal peripheral lung changes of ground glass opacity and/or consolidation, which are most commonly bilateral, may be present."#BMJEducation https://t.co/22nRTBVxmj
— The BMJ (@bmj_latest) July 19, 2020
COVID-19 in people with diabetes: understanding the reasons for worse outcomes
20 Jul, 2020 | 08:06h | UTCRelated: New-Onset Diabetes in Covid-19 – New England Journal of Medicine
Related Commentary on Twitter
#New #COVID19 content: Stefano Del Prato & colleagues review: #COVID-19 in people with #diabetes: understanding the reasons for worse outcomes https://t.co/7eYPmdsgvE pic.twitter.com/y9EmhG8Rsv
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) July 18, 2020
Review: clinical presentation and management of COVID ‐19
20 Jul, 2020 | 07:51h | UTCClinical presentation and management of COVID ‐19 – Medical Journal of Australia
The Zentensivist manifesto. Defining the art of critical care
20 Jul, 2020 | 07:42h | UTCThe Zentensivist Manifesto. Defining the Art of Critical Care – ATS Scholar
Source: Grupo UTIclínica – HCFMUSP
[Abstract Only] Randomized trial: urgent endoscopic retrograde cholangiopancreatography with sphincterotomy vs. conservative treatment in predicted severe acute gallstone pancreatitis
20 Jul, 2020 | 07:44h | UTC
Related Commentary on Twitter
Routine or on-demand ERCP in pred severe biliary #pancreatitis? APEC trial today @TheLancet: major complications 38%/117 pts urgent ERCP incl sphincterotomy vs 44%/113 pts with ERCP on-demand. ERCP can be reserved for cholangitis/ persistent cholestasis. https://t.co/kz1jfTQIf8 pic.twitter.com/ZfkARKwvGv
— Marc Besselink (@MarcBesselink) July 17, 2020
Palliative care for patients with severe Covid-19
17 Jul, 2020 | 08:51h | UTCPalliative care for patients with severe covid-19 – The BMJ
RIP Hydroxychloroquine? 2 studies show no benefit in early/mild COVID-19
17 Jul, 2020 | 08:59h | UTCCommentaries: New Covid-19 study, despite flaws, adds to case against hydroxychloroquine – STAT AND Hydroxychloroquine also doesn’t help Covid-19 patients who aren’t hospitalized, new study finds – CNN
Review: Perioperative management of oral glucose-lowering drugs in the patient with Type 2 Diabetes
17 Jul, 2020 | 08:24h | UTC
[Preprint] RECOVERY trial: effect of hydroxychloroquine in hospitalized patients with COVID-19
16 Jul, 2020 | 08:39h | UTC
Related Commentary on Twitter (Thread – Click for more)
HYDROXYCHLOROQUINE – Recovery trial results finally out – and hopefully puts nail in coffin. Out of 4700 people randomized… HCQ did NOT lower #covid19 mortality. It anything it was trending in wrong direction. Thread ? https://t.co/6Iu0NEejON pic.twitter.com/6l85Nmz4id
— Eric Feigl-Ding (@DrEricDing) July 15, 2020
Covid-19: experts criticize claim that remdesivir cuts death rates
16 Jul, 2020 | 08:31h | UTCCovid-19: Experts criticise claim that remdesivir cuts death rates – The BMJ
Related Commentary on Twitter
Experts have criticised pharmaceutical firm Gilead Sciences after it released data suggesting that its antiviral drug remdesivir can reduce death rates for patients with covid-19. They say the research is intrinsically flawed @MartinLandray https://t.co/a1q2FxMa7C
— The BMJ (@bmj_latest) July 14, 2020