Critical Care & Emergencies (all articles)
New WHO Guidance: Corticosteroids for COVID-19
3 Sep, 2020 | 11:20h | UTCCorticosteroids for COVID-19 – World Health Organization
News Release: WHO updates clinical care guidance with corticosteroid recommendations – World Health Organization
Commentaries: The WHO Now Recommends Cheap Steroids As a Life-Saving Treatment for Severe Covid-19 – Gizmodo AND Inexpensive steroids reduce deaths of hospitalized Covid-19 patients, WHO analysis confirms – STAT
Commentary on Twitter
🆕 guideline on use of dexamethasone & other corticosteroids advises:
✅ for oral or intravenous usage in treatment of patients with severe & critical #COVID19
❌ against usage in treatment of non-severe casesMore: https://t.co/eWHzRrYKvO
— World Health Organization (WHO) (@WHO) September 2, 2020
[Preprint] Randomized trial: Tocilizumab does not improve clinical status or mortality in hospitalized patients with COVID-19 pneumonia
3 Sep, 2020 | 11:19h | UTCTocilizumab in Hospitalized Patients With COVID-19 Pneumonia – medRxiv
Virus in the blood can predict severe COVID-19
3 Sep, 2020 | 11:11h | UTCVirus in the blood can predict severe COVID-19 – Karolinska Institutet
Original Study: SARS-CoV-2 RNA in serum as predictor of severe outcome in COVID-19: a retrospective cohort study – Clinical Infectious Diseases
Randomized trial: Similar outcomes with immediate angiography vs. delayed angiography after cardiac arrest
3 Sep, 2020 | 10:58h | UTCCoronary Angiography After Cardiac Arrest Without ST Segment Elevation: One-Year Outcomes of the COACT Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
Commentary: Angiography for Cardiac Arrest Survivors: No Need to Rush – MedPage Today (free registration required)
Commentary on Twitter
Coronary angiography after cardiac arrest without ST elevation. COACT Trial. Immediate angiography was not found to be superior to a strategy of delayed angiography with respect to outcomes at 1 year @JAMACardio @randreariba_rut https://t.co/07FIQjwTOQ
— Carles Falces (@CarlesFalces) September 3, 2020
Randomized trial: Effect of low tidal volume vs. conventional tidal volume on postoperative pulmonary complications in patients undergoing major surgery
3 Sep, 2020 | 10:57h | UTCEffect of Intraoperative Low Tidal Volume vs Conventional Tidal Volume on Postoperative Pulmonary Complications in Patients Undergoing Major Surgery: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
Normal lungs and the humans containing them don’t seem to mind how they’re ventilated (within reason). https://t.co/EdGVjm7esU
— Greg Bryson, MD, FRCPC (@glbryson) September 2, 2020
Study: Face shields, masks with valves ineffective against COVID-19 spread
2 Sep, 2020 | 09:55h | UTCFace Shields, Masks with Valves Ineffective Against COVID-19 Spread – American Institute of Physics
Original Study: Visualizing droplet dispersal for face shields and masks with exhalation valves – Physics of Fluids
Meta-analysis: Clinical manifestations, risk factors, and maternal and perinatal outcomes of Covid-19 in pregnancy
2 Sep, 2020 | 09:52h | UTC
#ESCCongress – [Not Published Yet] First randomized trial backs safety of ACE Inhibitors and ARBs in COVID-19 patients
2 Sep, 2020 | 09:48h | UTCNews Release: First randomised trial backs safety of common heart drugs in COVID-19 patients – European Society of Cardiology
Commentary on Twitter
Dr. Renato Lopes presents the BRACE CORONA trial: in patients hospitalized with COVID-19, suspending ACEI/ARB therapy for 30 days did not impact the number of days alive and out of hospital.
Full slide deck: https://t.co/avSK41bGSj#ESCCongress pic.twitter.com/2p0FH9U2RG
— C. Michael Gibson MD (@CMichaelGibson) September 1, 2020
#ESCCongress – [Not Published Yet] Randomized trial on transfusion thresholds in anemic heart attack patients
2 Sep, 2020 | 09:42h | UTCNews Release: Trial clarifies use of blood transfusion in anaemic heart attack patients – European Society of Cardiology
Position Paper: Diagnosis and treatment of pulmonary embolism during the COVID-19 pandemic
1 Sep, 2020 | 06:27h | UTC
Anticoagulation in COVID-19: A systematic review, meta-analysis and rapid guidance from the Mayo Clinic
1 Sep, 2020 | 06:26h | UTC
Practical guidance for tracheal intubation of patients with COVID-19
1 Sep, 2020 | 06:23h | UTCPractical Guidance for Tracheal Intubation of Patients With COVID-19 – Mayo Clinic Proceedings
A current review of COVID-19 for the cardiovascular specialist
1 Sep, 2020 | 06:06h | UTCA current review of COVID-19 for the cardiovascular specialist – American Heart Journal
A national strategy to diagnose COVID-19 associated invasive fungal disease in the ICU
31 Aug, 2020 | 01:44h | UTC
#ESCCongress – Randomized trial: Colchicine not beneficial for patients with acute coronary syndrome
31 Aug, 2020 | 01:26h | UTCCommentaries: Colchicine to Improve Cardiovascular Outcomes in ACS Patients – COPS – Circulation
Commentary on Twitter
Colchicine in Patients with Acute Coronary Syndrome: The Australian COPS RCT vs COLCOT RCT #ESCCongress 🔴 seemingly opposite results, dose start time patients? @almucastro01 @ValleAlfonso @JoseJuanatey @Dr_Manito @secardiologia @varrarte @sociedadSEEN 🤔🩺https://t.co/uagW2HRGPt pic.twitter.com/SQoVsbzG0m
— Oscar Moreno # (@moreno_perez_o) August 30, 2020
#ESCCongress – Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)
31 Aug, 2020 | 01:23h | UTCCommentary: Colchicine Cardiovascular Outcomes Trial – COLCOT – American College of Cardiology
Commentary on Twitter
#ESCCongress #COLCOT Study looking at TTI colchicine to assess if timing impacted outcomes
❤️ACS treatment with colchicine 🆚 placebo: 23%⤵️ in events
❤️Randomized w/in 30days postMI
🔺TTI (Time to Treat Initiation) 0-3d 🆚 4-7d 🆚 8-30d
🔺0-3 days had better outcomes pic.twitter.com/iQAkts1BG9— Dr. Martha Gulati ♥️🫀❤️🩹🇨🇦 (@DrMarthaGulati) August 30, 2020
#ESCCongress – 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
31 Aug, 2020 | 01:20h | UTCNews Release: How to treat the most common heart attacks – European Society of Cardiology
Commentary: 2020 ESC NSTE-ACS Guidelines: Key Points – American College of Cardiology
Commentary on Twitter
ESC 2020 Guidelines for non-ST elevation acute coronary syndrome just released https://t.co/dKIngRO59K#ESCCongress #ESCGuidelines #cardiotwitter #MedTwitter pic.twitter.com/ihcnxcCzBw
— European Society of Cardiology (@escardio) August 29, 2020
Updated Covid-19 Reviews: Hydroxychloroquine or Chloroquine / Masks / ACE Inhibitors or ARBs
28 Aug, 2020 | 08:54h | UTC- Update Alert 2: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19
- Update Alert 2: Masks for Prevention of Respiratory Virus Infections, Including SARS-CoV-2, in Health Care and Community Settings
- Update Alert 3: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults
Pathophysiology of COVID-19-associated acute respiratory distress syndrome: A multicenter prospective observational study
28 Aug, 2020 | 08:50h | UTC
Prevalence, risk factors, and outcomes of hospitalized patients with COVID-19 presenting as acute pancreatitis
28 Aug, 2020 | 08:41h | UTCCommentary: Covid-19 can present with pancreatitis – MedicalResearch.com
Too many COVID-19 patients get unneeded ‘just in case’ antibiotics
27 Aug, 2020 | 10:00h | UTCToo many COVID-19 patients get unneeded ‘just in case’ antibiotics – University of Michigan
[Abstract Only] Observational study: Therapeutic and prophylactic anticoagulation linked to lower in-hospital mortality in patients with Covid-19
27 Aug, 2020 | 09:51h | UTCCommentaries: Study provides more data on blood thinner efficacy for COVID-19 – The Mount Sinai Hospital AND Anticoagulants Associated With Better Survival, Lower Risk of Intubation in COVID-19 Patients
AHA Scientific Statement: Considerations for reduction of risk of perioperative stroke in adult patients undergoing cardiac and thoracic aortic operations
27 Aug, 2020 | 09:46h | UTCNews Release: Steps outlined to reduce the risk of stroke during, after heart surgery – American Heart Association
Top Things to Know: Considerations for Reduction of Risk of Perioperative Stroke in Adult Patients Undergoing Cardiac and Thoracic Aortic Operations
Commentary: Teamwork Needed to Reduce Stroke and Its Consequences in Cardiac Surgery: AHA – TCTMD
Lifting the mask on neurological manifestations of COVID-19
26 Aug, 2020 | 04:07h | UTCLifting the mask on neurological manifestations of COVID-19 – Nature Reviews Neurology
Systematic review: Effect of renin-angiotensin-aldosterone system inhibitors in patients with COVID-19
26 Aug, 2020 | 04:05h | UTCCommentaries: Expert reaction to study looking at blood pressure medicines and COVID-19 – Science Media Centre AND Coronavirus Treatment: Blood Pressure Medicines May Reduce COVID-19 Severity, Deaths: Study – International Business Times