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Critical Care

Guideline | Acute mesenteric ischemia.

31 Oct, 2022 | 13:58h | UTC

Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery – World Journal of Emergency Surgery

Related: Pre-post study: The implementation of a pathway and care bundle for the management of acute occlusive arterial mesenteric ischemia reduced mortality.

 

M-A | Comparison of continuous versus intermittent enteral feeding in critically ill patients.

31 Oct, 2022 | 13:48h | UTC

Comparison of continuous versus intermittent enteral feeding in critically ill patients: a systematic review and meta-analysis – Critical Care

 

Review | Optimal perfusion targets in cardiogenic shock.

31 Oct, 2022 | 13:45h | UTC

Optimal Perfusion Targets in Cardiogenic Shock – JACC: Advances

 

Commentary on Twitter

 

Evolving presentation of cardiogenic shock: a review of the medical literature and current practices.

31 Oct, 2022 | 13:46h | UTC

Evolving Presentation of Cardiogenic Shock: A Review of the Medical Literature and Current Practices – Cardiology and Therapy

 

Commentary on Twitter

 

M-A of RCT | Combination of ulinastatin and somatostatin evaluated in acute pancreatitis.

31 Oct, 2022 | 13:44h | UTC

The combination of ulinastatin and somatostatin reduces complication rates in acute pancreatitis: a systematic review and meta-analysis of randomized controlled trials – Scientific Reports

 

RCT | Early active mobilization during mechanical ventilation in the ICU did not improve outcomes and increased adverse events.

28 Oct, 2022 | 13:28h | UTC

Early Active Mobilization during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

https://twitter.com/NEJM/status/1585246120963604481

 

RCT | Haloperidol for the treatment of delirium in ICU patients did not significantly improve outcomes.

28 Oct, 2022 | 13:29h | UTC

Haloperidol for the Treatment of Delirium in ICU Patients – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

RCT | Spontaneous-breathing trials performed with pressure-support ventilation are no better than trials using a T-piece.

28 Oct, 2022 | 13:25h | UTC

Spontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

RCT | Selective decontamination of the GI tract did not significantly reduce mortality in ICU patients on mechanical ventilation.

27 Oct, 2022 | 12:40h | UTC

Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)

See also: Visual Abstract

Related study: Association Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis – JAMA (free for a limited period)

 

M-A | Selective decontamination of the GI tract may reduce in-hospital mortality in ICU patients receiving mechanical ventilation.

27 Oct, 2022 | 12:39h | UTC

Association Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis – JAMA (free for a limited period)

Related Study: Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)

 

RCT | A lower oxygen saturation target did not improve outcomes after out-of-hospital cardiac arrest.

27 Oct, 2022 | 12:38h | UTC

Effect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Early Oxygen Supplementation After Resuscitation From Cardiac Arrest – JAMA (free for a limited period)

Related:

RCT | In critically ill patients receiving MV, there was no difference in outcomes between different O2 saturation targets.

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one)

Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’ – Respirology

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

Higher versus lower oxygenation strategies in the general intensive care unit population: A systematic review, meta-analysis and meta-regression of randomized controlled trials – Journal of Critical Care

 

Retrospective Cohort Study | Association of ECMO with new mental health diagnoses in adult survivors of critical illness.

27 Oct, 2022 | 12:37h | UTC

Association of Extracorporeal Membrane Oxygenation With New Mental Health Diagnoses in Adult Survivors of Critical Illness – JAMA (free for a limited period)

Editorial: Mental Health Outcomes Following Extracorporeal Membrane Oxygenation in Survivors of Critical Illness – JAMA (free for a limited period)

News Release: ECMO survivors have higher rate of new mental health diagnoses than other ICU survivors – Ottawa Hospital

 

Commentary from the author on Twitter (thread – click for more)

 

Study commentary | From the management of altitude sickness to congestion in acute HF: a new season for acetazolamide?

27 Oct, 2022 | 12:27h | UTC

From the management of altitude sickness to treatment of congestion in acute heart failure: a new season for acetazolamide? – European Heart Journal (free for a limited period)

Original study: RCT | Acetazolamide resulted in faster decongestion in patients with acute decompensated heart failure with volume overload.

 

New horizons in Type 2 myocardial infarction: pathogenesis, assessment and management of an emerging geriatric disease.

26 Oct, 2022 | 14:27h | UTC

New horizons in Type 2 myocardial infarction: pathogenesis, assessment and management of an emerging geriatric disease – Age and Ageing

 

RCT | In critically ill patients receiving MV, there was no difference in outcomes between different O2 saturation targets.

25 Oct, 2022 | 13:23h | UTC

Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Study finds that the most common oxygen saturation targets for hospitalized patients appear equally safe and effective – Vanderbilt University Medical Center

Related:

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one)

Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’ – Respirology

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

Higher versus lower oxygenation strategies in the general intensive care unit population: A systematic review, meta-analysis and meta-regression of randomized controlled trials – Journal of Critical Care

 

Commentary on Twitter

 

Diaphragmatic function in cardiovascular disease: JACC review topic of the week.

25 Oct, 2022 | 13:22h | UTC

Diaphragmatic Function in Cardiovascular Disease: JACC Review Topic of the Week – Journal of the American College of Cardiology

 

Post-trial follow-up | IV calcium does not improve long-term outcomes in patients with out-of-hospital cardiac arrest.

25 Oct, 2022 | 13:17h | UTC

Effect of calcium vs. placebo on long-term outcomes in patients with out-of-hospital cardiac arrest – Resuscitation

Original Study: RCT: Intravenous or intraosseous calcium does not improve the return of spontaneous circulation in adults with out-of-hospital cardiac arrest.

 

Commentary on Twitter

 

Systematic Review | Point-of-care ultrasound in dyspnea, nontraumatic hypotension, and shock.

25 Oct, 2022 | 13:16h | UTC

POCUS in dyspnea, nontraumatic hypotension, and shock; a systematic review of existing evidence – European Journal of Internal Medicine

 

Brief Review | Management of oliguria.

21 Oct, 2022 | 13:04h | UTC

Management of oliguria – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 

Consensus Paper | Advanced bleeding control in combat casualty care.

21 Oct, 2022 | 12:59h | UTC

Advanced bleeding control in combat casualty care: An international, expert-based Delphi consensus – Journal of Trauma and Acute Care Surgery

 

Clinical practice update for management of acute kidney injury associated with cardiac surgery.

20 Oct, 2022 | 12:31h | UTC

Society of Cardiovascular Anesthesiologists Clinical Practice Update for Management of Acute Kidney Injury Associated With Cardiac Surgery – Anesthesia & Analgesia (free for a limited period)

 

Commentary on Twitter

 

Review | Update on the management of upper gastrointestinal bleeding.

20 Oct, 2022 | 12:29h | UTC

Update on the management of upper gastrointestinal bleeding – BMJ Medicine

 

Cohort Study | Intravenous potassium and magnesium linked to spontaneous conversion of atrial fibrillation in the ED.

20 Oct, 2022 | 12:27h | UTC

Association of Intravenous Potassium and Magnesium Administration With Spontaneous Conversion of Atrial Fibrillation and Atrial Flutter in the Emergency Department – JAMA Network Open

 

Commentary on Twitter

 

Pneumonia update for emergency clinicians.

19 Oct, 2022 | 14:19h | UTC

Pneumonia Update for Emergency Clinicians – Current Emergency and Hospital Medicine Reports

 

M-A | Nasal protection strategy reduces the incidence of nasal pressure injuries during nasotracheal intubation.

19 Oct, 2022 | 14:13h | UTC

Nasal protection strategy reduces the incidence of nasal pressure injuries during nasotracheal intubation: Meta-analysis with trial sequential analysis – Medicine

 

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