Critical Care | Page 18 of 78 | Links Medicus Content Curation & Alerts in Medicine

Deconstructing the dogma: meta-analysis of adjunctive gentamicin and rifampin in staphylococcal prosthetic valve endocarditis

2 Feb, 2023 | 15:00h | UTC

Deconstructing the Dogma: Systematic Literature Review and Meta-analysis of Adjunctive Gentamicin and Rifampin in Staphylococcal Prosthetic Valve Endocarditis – Open Forum Infectious Diseases

Commentary on Twitter

So excited to share an #IDTwitter collaborative article!

Together with @Cortes_Penfield @DrToddLee @syctong @DrEmilyMcD @JGPharmD and Irani Thevarajan, we did a systematic review & meta-analysis on gent & rifampin in Staph prosthetic valve endocarditis!https://t.co/XocwPvut3x

— Jonathan Ryder, MD (@JonathanRyderMD) October 31, 2022

Guideline Update | Acute stroke management

2 Feb, 2023 | 14:56h | UTC

Canadian Stroke Best Practice Recommendations: Acute Stroke Management, 7th Edition Practice Guidelines Update, 2022

AHA/ASA Guideline: Prevention of stroke in patients with previous stroke and transient ischemic attack – prevention efforts should be based on the cause of the first ischemic event.

Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

2 recent meta-analysis highlight the benefits of short term (30 days) dual antiplatelet therapy with aspirin + clopidogrel in patients within 24 hours of high-risk transient ischemic attack or mild-moderate ischemic stroke.

Systematic review: Multiple vs. fewer antiplatelet agents for preventing early recurrence after ischemic stroke or transient ischemic attack

M-A | Diagnostic value of bronchoalveolar lavage fluid galactomannan assay for invasive pulmonary aspergillosis

2 Feb, 2023 | 14:50h | UTC

Diagnostic value of bronchoalveolar lavage fluid galactomannan assay for invasive pulmonary aspergillosis in adults: A meta-analysis – Journal of Clinical Pharmacy and Therapeutics

Review | Perioperative evaluation and management of patients on glucocorticoids

2 Feb, 2023 | 14:35h | UTC

Perioperative Evaluation and Management of Patients on Glucocorticoids – Journal of the Endocrine Society

RCT | Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery

1 Feb, 2023 | 12:58h | UTC

Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): A single-centre, parallel-arm, randomised, placebo-controlled superiority trial – eClinicalMedicine

Commentary: Short Dose of Intravenous Sedative May Help Prevent Postoperative Delirium After Heart Surgery – Massachusetts General Hospital

M-A | Mucolytics for acute exacerbations of COPD

31 Jan, 2023 | 13:56h | UTC

Mucolytics for acute exacerbations of chronic obstructive pulmonary disease: a meta-analysis – European Respiratory Review

Cohort Study | Severe lymphopenia may predict worse outcomes in hospitalized patients with pneumococcal CAP

31 Jan, 2023 | 13:52h | UTC

Impact of severe lymphopenia on the early prediction of clinical outcome in hospitalized patients with pneumococcal community-acquired pneumonia – Infection (if the link is paywalled, try this one in PMC)

Podcast | Acute exacerbations of COPD

31 Jan, 2023 | 13:48h | UTC

#378 Acute Exacerbations of COPD (AECOPD) – The Curbsiders

Perspective | ARDS: hidden perils of an overburdened diagnosis

31 Jan, 2023 | 13:36h | UTC

ARDS: hidden perils of an overburdened diagnosis – Critical Care

M-A | Vancomycin area under the curve vs. trough only guided dosing and the risk of acute kidney injury

31 Jan, 2023 | 13:32h | UTC

Vancomycin area under the curve versus trough only guided dosing and the risk of acute kidney injury: Systematic review and meta-analysis – Pharmacology

Guideline | Management of adult renal trauma

30 Jan, 2023 | 01:20h | UTC

Management of adult renal trauma: a practice management guideline from the eastern association for the surgery of trauma – BMC Surgery

Kidney and uro-trauma: WSES-AAST guidelines – World Journal of Emergency Surgery

Urotrauma: AUA Guideline – The Journal of Urology

Urological Trauma – European Association of Urology

Renal trauma: the current best practice – Therapeutic Advances in Urology

RCT | Early extracorporeal CPR did not improve outcomes in patients with refractory out-of-hospital cardiac arrest

30 Jan, 2023 | 01:18h | UTC

Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Early Extracorporeal CPR for Out-of-Hospital Cardiac Arrest – American College of Cardiology

Commentary on Twitter

In a randomized trial, patients with out-of-hospital cardiac arrest who received extracorporeal CPR and those who received conventional CPR had similar results for survival and favorable neurologic outcomes. https://t.co/Irw8nrV8AA pic.twitter.com/lOPsBzhP3O

— NEJM (@NEJM) January 27, 2023

Practice Guidance | Anticoagulation in adult patients supported with extracorporeal membrane oxygenation

30 Jan, 2023 | 00:56h | UTC

Anticoagulation in adult patients supported with extracorporeal membrane oxygenation: guidance from the Scientific and Standardization Committees on Perioperative and Critical Care Haemostasis and Thrombosis of the International Society on Thrombosis and Haemostasis – Journal of Thrombosis and Haemostasis

M-A | The optimal timing and intervention to reduce mortality for necrotizing pancreatitis

30 Jan, 2023 | 00:44h | UTC

The optimal timing and intervention to reduce mortality for necrotizing pancreatitis: a systematic review and network meta-analysis – World Journal of Emergency Surgery

Long-term follow-up of a RCT | Endoscopic versus surgical step-up approach for infected necrotizing pancreatitis.

RCT: Immediate drainage did not improve outcomes compared to postponed intervention in patients with infected necrotizing pancreatitis.

An Endoscopic Transluminal Approach, Compared With Minimally Invasive Surgery, Reduces Complications and Costs for Patients With Necrotizing Pancreatitis – Gastroenterology

Research: Endoscopic or Surgical Step-up Approach for Infected Necrotising Pancreatitis

Evidence-Based Approach to the Surgical Management of Acute Pancreatitis – The Surgery Journal

Intravenous fluid therapy in patients with severe acute pancreatitis admitted to the intensive care unit: a narrative review – Intensive Care Medicine

Aggressive or Moderate Fluid Resuscitation in Acute Pancreatitis – New England Journal of Medicine (link to abstract – $ for full-text)

Acute Pancreatitis: Diagnosis and Treatment – Drugs

Revised Clinical Practice Guidelines of the Korean Pancreatobiliary Association for Acute Pancreatitis – Gut and Liver

Guidelines for the management of patients with severe acute pancreatitis, 2021 – Anaesthesia Critical Care & Pain Medicine

Evidence-Based Disposition of Acute Pancreatitis – emDocs

2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

Pancreatitis – National Institute for Health and Care Excellence

Toward nutrition improving outcome of critically ill patients: how to interpret recent feeding RCTs?

30 Jan, 2023 | 00:42h | UTC

Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs? – Critical Care

RCT | Simple aspiration versus drainage for complete pneumothorax

30 Jan, 2023 | 00:40h | UTC

Simple Aspiration Versus Drainage for Complete Pneumothorax: A Randomized Non-Inferiority Trial – Am J Respir Crit Care Med (link to abstract – $ for full-text)

RCT | Higher protein dosing did not improve outcomes in critically ill patients with high nutritional risk

27 Jan, 2023 | 12:24h | UTC

The effect of higher protein dosing in critically ill patients with high nutritional risk (EFFORT Protein): an international, multicentre, pragmatic, registry-based randomised trial – The Lancet (link to abstract – $ for full-text)

Commentary on Twitter (thread – click for more)

Researchers aimed to test the hypothesis that a higher dose of protein provided to critically ill patients would improve clinical outcomes.

Here's what they found ? /4 https://t.co/C5JswTr82o

— The Lancet (@TheLancet) January 26, 2023

Perspective | Is it time to retire the diagnosis “hypertensive emergency”?

27 Jan, 2023 | 12:26h | UTC

Is it Time to Retire the Diagnosis “Hypertensive Emergency”? – Journal of the American Heart Association

Review | The blood–brain barrier and optimization of antibiotics for the treatment of CNS infections in adults

27 Jan, 2023 | 11:55h | UTC

The Blood–Brain Barrier and Pharmacokinetic/Pharmacodynamic Optimization of Antibiotics for the Treatment of Central Nervous System Infections in Adults – Antibiotics

RCT | Continued enteral nutrition until extubation was noninferior to a 6-h fasting strategy before extubation in patients in the ICU

26 Jan, 2023 | 12:49h | UTC

Continued enteral nutrition until extubation compared with fasting before extubation in patients in the intensive care unit: an open-label, cluster-randomised, parallel-group, non-inferiority trial – The Lancet Respiratory Medicine (free registration required)

Invited Commentary: Continuation of enteral nutrition until extubation in critically ill patients – The Lancet Respiratory Medicine

Commentary on Twitter

NEW Research—Continued enteral nutrition until extubation in critically ill patients in the ICU is a practice that could be safe to implement and be associated with potential benefits

Read the trial from Mickaël Landais & colleagues here: https://t.co/iAvet2DNjN #SCCM2023 pic.twitter.com/SBal9qkAyQ

— The Lancet Respiratory Medicine (@LancetRespirMed) January 21, 2023

Review | Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT)

26 Jan, 2023 | 12:46h | UTC

Spotlight on vaccine-induced thrombosis and thrombocytopenia (VITT) – Blood

Evidence-Based Guidance | Medical nutrition therapy in ECMO patients

26 Jan, 2023 | 12:28h | UTC

Medical Nutrition Therapy in ECMO Patients: Evidence-Based Guidance for Clinical Practice – Journal of Parenteral and Enteral Nutrition

Cohort study | Endovascular balloon occlusion of the aorta may be an alternative to resuscitative thoracotomy in traumatic hemorrhagic shock

26 Jan, 2023 | 12:18h | UTC

Zone 1 Endovascular Balloon Occlusion of the Aorta vs Resuscitative Thoracotomy for Patient Resuscitation After Severe Hemorrhagic Shock – JAMA Surgery (link to abstract – $ for full-text)

Commentary on Twitter

Cohort study using the @traumadoctors AORTA registry suggests that zone 1 endovascular balloon occlusion of the aorta is an effective alternative to resuscitative thoracotomy with similar or better survival rates. https://t.co/QqyXRlPtOb #Research #REBOA

— JAMA Surgery (@JAMASurgery) December 22, 2022