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Critical Care

[Not published yet] Dual blood thinners under prescribed after minor or warning stroke, especially in women

9 Feb, 2023 | 14:01h | UTC

Dual blood thinners under prescribed after minor or warning stroke, especially in women – American Heart Association

Related:

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials – Stroke

Efficacy and Safety of Using Dual Versus Monotherapy Antiplatelet Agents in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials – Circulation

Multiple versus fewer antiplatelet agents for preventing early recurrence after ischaemic stroke or transient ischaemic attack – Cochrane Library

 


How to use biomarkers of infection or sepsis at the bedside: guide to clinicians

9 Feb, 2023 | 13:26h | UTC

How to use biomarkers of infection or sepsis at the bedside: guide to clinicians – Intensive Care Medicine

 

Commentary on Twitter

 


Brief Review | Acute kidney injury

9 Feb, 2023 | 13:25h | UTC

Acute kidney injury – Intensive Care Medicine

 

Commentary on Twitter

 


Review | Liberation from mechanical ventilation in the cardiac intensive care unit

8 Feb, 2023 | 12:45h | UTC

Liberation From Mechanical Ventilation in the Cardiac Intensive Care Unit – JACC: Advances

 


A decision guide for assessing the recently extubated patient’s readiness for safe oral intake

8 Feb, 2023 | 12:28h | UTC

A Decision Guide for Assessing the Recently Extubated Patient’s Readiness for Safe Oral Intake – Critical Care Nurse

News Release: Decision guide provides specific guidelines for swallowing care after extubation – American Association of Critical-Care Nurses (AACN)/News Medical

 


Guideline | Assessment and management of complex fractures

7 Feb, 2023 | 14:19h | UTC

Fractures (complex): assessment and management – National Institute for Health and Care Excellence

 


Guideline | Delirium: prevention, diagnosis and management in hospital and long-term care

7 Feb, 2023 | 14:21h | UTC

Delirium: prevention, diagnosis and management in hospital and long-term care – National Institute for Health and Care Excellence

 


RCT | Paxlovid did not improve outcomes in hospitalized patients with Covid-19

7 Feb, 2023 | 14:08h | UTC

Efficacy and safety of Paxlovid in severe adult patients with SARS-Cov-2 infection: a multicenter randomized controlled study – The Lancet Regional Health Western Pacific

 


M-A | Heparin full-dose anticoagulation is beneficial for non-critically ill COVID-19 patients

7 Feb, 2023 | 14:06h | UTC

The Effect of Heparin Full-Dose Anticoagulation on Survival of Hospitalized, Non-critically Ill COVID-19 Patients: A Meta-analysis of High Quality Studies – Lung

Related:

#ESCCongress | In critically ill patients with COVID-19, full-dose anticoagulation reduced thrombotic events but increased the risk of bleeding.

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Efficacy and safety of heparin full-dose anticoagulation in hospitalized non-critically ill COVID-19 patients: a meta-analysis of multicenter randomized controlled trials – Journal of Thrombosis and Thrombolysis

Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19: a systematic review and meta-analysis – Open Forum Infectious Diseases

Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

 


Review | Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury

7 Feb, 2023 | 13:32h | UTC

Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: A narrative review – Frontiers in Physiology

 


Can the future of ID escape the inertial dogma of its past? The exemplars of shorter is better and oral is the new IV

7 Feb, 2023 | 13:34h | UTC

Can the Future of ID Escape the Inertial Dogma of Its Past? The Exemplars of Shorter Is Better and Oral Is the New IV – Open Forum Infectious Diseases

 


Review | Dead space ventilation-related indices: bedside tools to evaluate the ventilation and perfusion relationship in patients with ARDS

6 Feb, 2023 | 13:18h | UTC

Dead space ventilation-related indices: bedside tools to evaluate the ventilation and perfusion relationship in patients with acute respiratory distress syndrome – Critical Care

 


Cohort Study | Predictors of acute coronary occlusion in patients with out-of-hospital cardiac arrest without ST-segment elevation

3 Feb, 2023 | 14:20h | UTC

Acute Coronary Occlusion in Patients With Non-ST-Segment Elevation Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)

JACC Podcast: Acute Coronary Occlusion in Patients with Non-ST-segment Elevation Out-of-hospital Cardiac Arrest

Commentary: Coronary Occlusion in Patients With Non-ST Elevation Cardiac Arrest – American College of Cardiology

Related:

#ESCCongress – RCT: Immediate coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation did not improve outcomes compared to delayed/selective angiography – New England Journal of Medicine

Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial – JAMA Cardiology (link to abstract – $ for full-text)

 


M-A | Cardiovascular and renal effects of SGLT2 inhibitor initiation in acute heart failure

3 Feb, 2023 | 14:23h | UTC

Cardiovascular and renal effects of SGLT2 inhibitor initiation in acute heart failure: a meta-analysis of randomized controlled trials – Clinical Research in Cardiology

 


Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit

3 Feb, 2023 | 14:15h | UTC

Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit – Intensive Care Medicine

 

Commentary on Twitter

 


Review | How to optimize extubation?

3 Feb, 2023 | 14:13h | UTC

How to optimize extubation? – Intensive Care Medicine

 

Commentary on Twitter

 


Ten recommendations for child-friendly visiting policies in critical care

3 Feb, 2023 | 14:14h | UTC

Ten recommendations for child-friendly visiting policies in critical care – Intensive Care Medicine

 

Commentary on Twitter

 


Transfusion thresholds for acute coronary syndromes — insights from the TRICS‐III trial and meta‐analysis

3 Feb, 2023 | 13:58h | UTC

Transfusion Thresholds for Acute Coronary Syndromes—Insights From the TRICS‐III Randomized Controlled Trial, Systematic Review, and Meta‐Analysis – Journal of the American Heart Association

 


RCT | Remifentanil vs. neuromuscular blockers during rapid sequence intubation in patients at risk of aspiration

2 Feb, 2023 | 15:01h | UTC

Effect of Remifentanil vs Neuromuscular Blockers During Rapid Sequence Intubation on Successful Intubation Without Major Complications Among Patients at Risk of Aspiration: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Deconstructing the dogma: meta-analysis of adjunctive gentamicin and rifampin in staphylococcal prosthetic valve endocarditis

2 Feb, 2023 | 15:00h | UTC

Deconstructing the Dogma: Systematic Literature Review and Meta-analysis of Adjunctive Gentamicin and Rifampin in Staphylococcal Prosthetic Valve Endocarditis – Open Forum Infectious Diseases

 

Commentary on Twitter

 


Guideline Update | Acute stroke management

2 Feb, 2023 | 14:56h | UTC

Canadian Stroke Best Practice Recommendations: Acute Stroke Management, 7th Edition Practice Guidelines Update, 2022

Related:

AHA/ASA Guideline: Prevention of stroke in patients with previous stroke and transient ischemic attack – prevention efforts should be based on the cause of the first ischemic event.

Stroke and transient ischaemic attack in over 16s: diagnosis and initial management – National Institute for Health and Care Excellence

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

2 recent meta-analysis highlight the benefits of short term (30 days) dual antiplatelet therapy with aspirin + clopidogrel in patients within 24 hours of high-risk transient ischemic attack or mild-moderate ischemic stroke.

Systematic review: Multiple vs. fewer antiplatelet agents for preventing early recurrence after ischemic stroke or transient ischemic attack

 


M-A | Diagnostic value of bronchoalveolar lavage fluid galactomannan assay for invasive pulmonary aspergillosis

2 Feb, 2023 | 14:50h | UTC

Diagnostic value of bronchoalveolar lavage fluid galactomannan assay for invasive pulmonary aspergillosis in adults: A meta-analysis – Journal of Clinical Pharmacy and Therapeutics

 


Review | Perioperative evaluation and management of patients on glucocorticoids

2 Feb, 2023 | 14:35h | UTC

Perioperative Evaluation and Management of Patients on Glucocorticoids – Journal of the Endocrine Society

Related: Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings

 


RCT | Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery

1 Feb, 2023 | 12:58h | UTC

Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): A single-centre, parallel-arm, randomised, placebo-controlled superiority trial – eClinicalMedicine

Commentary: Short Dose of Intravenous Sedative May Help Prevent Postoperative Delirium After Heart Surgery – Massachusetts General Hospital

 


M-A | Mucolytics for acute exacerbations of COPD

31 Jan, 2023 | 13:56h | UTC

Mucolytics for acute exacerbations of chronic obstructive pulmonary disease: a meta-analysis – European Respiratory Review

 


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