Chest Medicine
Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review
28 Mar, 2021 | 22:40h | UTCInterleukin‐6 blocking agents for treating COVID‐19: a living systematic review – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1375456773486874628
Opinion | COVID-19 Is Different Now: The coronavirus is changing. So is the disease it causes.
28 Mar, 2021 | 22:44h | UTCCOVID-19 Is Different Now – The Atlantic
Pushing back against U.S. health officials, AstraZeneca says new analysis confirms efficacy of its Covid-19 vaccine
26 Mar, 2021 | 09:01h | UTCNews release: AZD1222 US Phase III primary analysis confirms safety and efficacy – AstraZeneca
See also: Latest results put Oxford–AstraZeneca COVID vaccine back on track – Nature AND AstraZeneca’s absurd and unprecedented dispute with regulators, explained – Vox AND Expert reaction to press release from AstraZeneca announcing primary data on safety and efficacy from the US trial of the Oxford-AstraZeneca COVID-19 vaccine – Science Media Centre AND AstraZeneca says COVID-19 vaccine 76% effective in new analysis, to seek U.S. approval – Reuters AND AstraZeneca’s new data showing Covid vaccine slightly less effective than suggested doesn’t worry experts – The Guardian AND Latest AstraZeneca Report Supports Effectiveness Of COVID Vaccine – NPR
Practice Pointer: Remote management of Covid-19 using home pulse oximetry and virtual ward support
26 Mar, 2021 | 09:05h | UTCRemote management of covid-19 using home pulse oximetry and virtual ward support – The BMJ
Related: Virtual clinics are reassuring but sometimes daunting – The BMJ
Commentary on Twitter
https://twitter.com/trishgreenhalgh/status/1375110854094520322
RCT: Similar number of days free of respiratory support with helmet noninvasive ventilation vs. high-flow nasal oxygen in patients with COVID-19 and moderate to severe hypoxemic respiratory failure
26 Mar, 2021 | 09:02h | UTCEffect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure: The HENIVOT Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Respiratory Support During the COVID-19 Pandemic: Is It Time to Consider Using a Helmet?
Video: Helmet Noninvasive Ventilation of COVID-19 Patients
Another study shows increased transmissibility of SARS-CoV-2 lineage B.1.1.7 with a 50% to 100% higher reproduction number
26 Mar, 2021 | 08:57h | UTCAssessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England – Nature
Related: Study confirms higher transmissibility of SARS-CoV-2 lineage B.1.1.7 (study and commentary)
Commentary on Twitter
Just published @nature: Transmissibility of the B.1.1.7 (UK) variant https://t.co/dsMge8bB83 "A substantial transmission advantage with a 50 to 100% higher reproduction number"
Secondary attack rates were 30-40% higher than ancestral strain (non-VOC); no age gradient by modeling pic.twitter.com/870A3PojyF— Eric Topol (@EricTopol) March 25, 2021
Covid: The London bus trip that saved maybe a million lives (about the creation of the RECOVERY Trial)
26 Mar, 2021 | 08:53h | UTCCovid: The London bus trip that saved maybe a million lives – BBC
Related: Covid-19: The Inside Story of the RECOVERY Trial
Commentary on Twitter
Very cool story by @JamesTGallagher about a convo on a London bus that led to the creation of the RECOVERY trial, which has been a shining (& too rare) example of how to do critical research in a pandemic. Bravo @PeterHorby & @MartinLandray h/t @hildabast https://t.co/BRSJLSFXdc
— Helen Branswell 🇨🇦 (@HelenBranswell) March 25, 2021
[Press release – not published yet] Trial of multi drug-resistant TB treatment ends enrolment early after independent board indicates new regimen is superior
25 Mar, 2021 | 08:10h | UTC
Commentary on Twitter
Promising news improving treatment #MDR #TB https://t.co/Lxjb7LBofy Translating findings to available drugs & diagnostics back it up will be key pic.twitter.com/YGp8d9ixww
— Michael Marks (@dr_michaelmarks) March 24, 2021
WHO Campaign | World Tuberculosis Day 2021: The Clock Is Ticking
24 Mar, 2021 | 08:16h | UTCWorld Tuberculosis Day 2021: The Clock Is Ticking – World Health Organization
Perspective | New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications
25 Mar, 2021 | 08:34h | UTC
Systematic review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
25 Mar, 2021 | 08:38h | UTCCommentaries: Updated Cochrane review assesses how accurate rapid tests are for detecting COVID-19 – Wiley AND Expert reaction to updated Cochrane review of studies on accuracy of rapid tests (including lateral flow and molecular tests) to detect SARS-CoV-2 – Science Media Centre
NICE publishes single guideline for managing COVID-19
24 Mar, 2021 | 08:42h | UTCNews release: COVID-19 rapid guideline: managing COVID-19 – National Institute for Health and Care Excellence
Commentary on Twitter
Today NICE has published a single guideline for managing COVID-19, which brings together content from previous rapid COVID-19 guidance and evidence summaries. Read more: https://t.co/3O5yzpHK9e pic.twitter.com/DyD7lcLX8v
— NICE (@NICEComms) March 23, 2021
WHO Guideline: Screening for Tuberculosis Disease
24 Mar, 2021 | 08:13h | UTCSee also: WHO Operational Handbook on Systematic Screening for Tuberculosis – World Health Organization
Fully vaccinated people can visit unvaccinated family and friends, but one household at a time, CDC official says
24 Mar, 2021 | 08:26h | UTCUpdated Guidance: When You’ve Been Fully Vaccinated – Centers for Disease Control and Prevention
Pfizer coronavirus vaccine found to be moderately less effective against B.1.351 variant
24 Mar, 2021 | 08:35h | UTCNews release: Pfizer vaccine less effective against South African variant, study finds – Ben-Gurion University of the Negev
Commentary on Twitter
SARS-CoV-2 variants & neutralization: @RanTaube &Co assess #SARSCoV2 neutralization activity of convalescent or Pfizer-vaccinee sera. While vaccinee sera comparably neutralizes WT& B.1.1.7 pseudoviruses, B.1.351 moderately resists vaccine neutralization https://t.co/wucbeLY075 pic.twitter.com/B1y7vFsMDL
— Cell Host & Microbe (@cellhostmicrobe) March 22, 2021
Editorial | Covid-19: variants and vaccination
24 Mar, 2021 | 08:32h | UTCCovid-19: variants and vaccination – The BMJ
World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis
24 Mar, 2021 | 08:19h | UTCSee also: 1.4 million with tuberculosis, lost out on treatment during first year of COVID-19 – United Nations
Perspective | Don’t Be Surprised When Vaccinated People Get Infected
24 Mar, 2021 | 08:28h | UTCDon’t Be Surprised When Vaccinated People Get Infected – The Atlantic
Opinion | Perfect as the enemy of good: tracing transmissions with low-sensitivity tests to mitigate SARS-CoV-2 outbreaks
24 Mar, 2021 | 08:22h | UTC
Commentary on Twitter
Editor's Pick—How do different contact tracing & testing methods work? What resources are needed for each? How do features of #COVID19 transmission influence their effectiveness?
Read the Personal View by @LeeKShaffer et al. in @LancetMicrobe. https://t.co/ruHV0RW6aY pic.twitter.com/19f7vCrt0I
— The Lancet (@TheLancet) March 18, 2021
[Press release – not published yet] AstraZeneca vaccine 79% effective for preventing symptomatic COVID-19
23 Mar, 2021 | 02:36h | UTCCommentaries: AstraZeneca vaccine is 79% effective against symptomatic Covid-19, company says – CNN AND AstraZeneca’s Covid-19 vaccine shows better-than-expected efficacy in U.S. trial – STAT AND Expert reaction to press release from AstraZeneca announcing interim data on safety and efficacy from the US trial of the Oxford-AstraZeneca COVID-19 vaccine – Science Media Centre AND AstraZeneca Publishes Reassuring Trial Data, But Vaccine Hesitancy Remains Widespread In European Union – Health Policy Watch
Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery
23 Mar, 2021 | 02:33h | UTCSARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery – Anaesthesia
Commentary on Twitter
Our research has underpinned key recommendations in new guidance on SARS-CoV-2 infection & elective surgery from @Assoc_Anaes & @RCoANews & @RCSnews.
This guideline can act as a template for policy makers in other countries!
🆓https://t.co/kKgJXFf0vd pic.twitter.com/mJRasJTJws
— COVIDSurg (@CovidSurg) March 20, 2021
EMA advises against use of ivermectin for the prevention or treatment of COVID-19 outside randomized clinical trials
23 Mar, 2021 | 02:30h | UTCRelated: FDA: Why you should not use Ivermectin to treat or prevent COVID-19 (statement, commentary, and RCT)
Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review
23 Mar, 2021 | 02:31h | UTC
Opinion | We need to start thinking more critically — and speaking more cautiously — about long Covid
23 Mar, 2021 | 02:28h | UTCWe need to start thinking more critically — and speaking more cautiously — about long Covid – STAT
Review | Post-acute COVID-19 syndrome
23 Mar, 2021 | 02:26h | UTCPost-acute COVID-19 syndrome – Nature Medicine
News Release: Study underscores need for multidisciplinary care for COVID-19 long-haulers – Dana-Farber Cancer Institute