Chest Medicine
Long Covid Implications for the workplace
6 Apr, 2021 | 01:15h | UTCLong Covid Implications for the workplace – Occupational Medicine
Probable airborne transmission of SARS-CoV-2 in a poorly ventilated restaurant
6 Apr, 2021 | 01:27h | UTCRelated: Why indoor spaces are still prime COVID hotspots – Nature
Commentary on Twitter (thread – click for more)
📍AIRBORNE RESTAURANT TRANSMISSION—3 families—“No close contact or fomite contact identified, aside from back-to-back sitting—Airflow dynamics indicates the infection distribution is consistent with a spread of **long-range transmission of exhaled virus-laden aerosols**”. 🧵 pic.twitter.com/kapgqumWnV
— Eric Feigl-Ding (@DrEricDing) April 5, 2021
Epidemiologic Evidence for Airborne Transmission of SARS-CoV-2 during Church Singing
6 Apr, 2021 | 01:26h | UTCRelated: Why indoor spaces are still prime COVID hotspots – Nature
Commentary on Twitter
Pretty interesting report of #Covid19 transmission during church services in Australia. Infected choir member appears to have transmitted to up to 12 church goers, some seated more than 15 meters from the choir loft. No masks. Yes, likely airborne. https://t.co/w5CKMsaKp9 pic.twitter.com/Wmi6jxOPox
— Helen Branswell 🇨🇦 (@HelenBranswell) April 5, 2021
Reactogenicity Following Receipt of mRNA-Based COVID-19 Vaccines
6 Apr, 2021 | 01:21h | UTCReactogenicity Following Receipt of mRNA-Based COVID-19 Vaccines – JAMA
Commentaries on Twitter
This @JAMA_current paper summarizes adverse reactions to mRNA #COVID19 vaccines through @CDCgov v-safe surveillance system, which collects near–real-time data via smartphone text message prompts and web-based health surveys. https://t.co/Xbdg0lxYfK pic.twitter.com/E4q13aJfkZ
— Muin J. Khoury (@MuinJKhoury) April 5, 2021
.@CDCgov's v-safe program collects near–realtime data from US #COVID19 vaccine recipients. V-safe participants self-enroll and receive smartphone text messages to initiate web-based health health surveys from the day of vaccination (day 0) through 12 mo https://t.co/utJNibTTd9
— JAMA (@JAMA_current) April 5, 2021
Cohort study: Association between pre-existing respiratory disease and its treatment, and severe COVID-19
6 Apr, 2021 | 01:17h | UTC
M-A: High versus low PEEP levels for mechanically ventilated adult patients with acute lung injury and ARDS
5 Apr, 2021 | 01:19h | UTC
U.S. Saw Over 520,000 Excess Deaths in 2020, Most from COVID-19
6 Apr, 2021 | 01:18h | UTCU.S. Saw Over 520,000 Excess Deaths in 2020, Most from COVID-19 – NEJM Journal Watch
Original study: Excess Deaths From COVID-19 and Other Causes in the US, March 1, 2020, to January 2, 2021 – JAMA
Editorial: Learning From Excess Pandemic Deaths – JAMA
Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates
5 Apr, 2021 | 01:52h | UTCVideo: Home Oxygen Instructions for Discharged Patients With COVID-19
Commentaries: Covid-19: Ambulatory Management with Home Oxygen Results in Low Mortality, Low Readmissions – Physician’s Weekly AND Mortality, readmission low with COVID-19 discharge on home oxygen – HealthDay
Commentaries on Twitter
Is “HOME O2” safe in #COVID19? @JAMANetworkOpen
N=621 #COVID Pts D/Ced on O2 instead of being kept in hosp. 20% BMI>30, 33% HTN/DM. Only 1.2% 30-d Mort rate & only 8.5% returned for hosp admission. Safe is done right!https://t.co/clZAzEqWwy#medtwitter #CriticalCare #Nurse pic.twitter.com/EInhCdcN6f— WesElyMD (@WesElyMD) April 3, 2021
Cohort study finds #COVID19 patients discharged with home oxygen from the LA safety net public hospital system using an innovative program had similar outcomes to patients not requiring home oxygen. @BradSpellberg @LACUSCMedCenter https://t.co/kZrxVKHB5F
— JAMA Network Open (@JAMANetworkOpen) April 1, 2021
Cohort study: High thrombotic risk in cancer patients receiving immunotherapy
5 Apr, 2021 | 01:08h | UTCHigh thrombotic risk in cancer patients receiving immunotherapy – Medical University of Vienna
Original study: Incidence, risk factors, and outcomes of venous and arterial thromboembolism in immune checkpoint inhibitor therapy – Blood
Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries
5 Apr, 2021 | 01:49h | UTCCommentary: Criteria for selecting COVID-19 patients for lung lung transplantation – Medical University of Vienna
Commentary on Twitter
NEW Research—Lung transplantation is the only option for survival in some patients with severe, unresolving #COVID19-associated #ARDS
From Ankit Bharat & colleagues https://t.co/7u52IJSOIn, including a fantastic video abstract https://t.co/2cjfTLXR8R
— The Lancet Respiratory Medicine (@LancetRespirMed) April 1, 2021
Perspective | Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination
5 Apr, 2021 | 01:39h | UTCConcerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination – Nature
Commentary on Twitter
A concern raised about delaying the 2nd vaccine dose is the potential to promote immune escape, new mutations. A new @NatRevImmunol essay argues against that possibility (may even be the opposite) https://t.co/XlCOP5DwTf by @sarahcobey @DanLarremore @yhgrad @mlipsitch pic.twitter.com/ehVOPX9sQv
— Eric Topol (@EricTopol) April 2, 2021
Exceedingly rare side effects reported with AstraZeneca vaccine in the UK – 22 cases of cerebral venous sinus thrombosis with low levels of platelets out of 18 million vaccinated individuals
5 Apr, 2021 | 01:45h | UTCCovid-19: Seven UK blood clot deaths after AstraZeneca vaccine – BBC
Original report: Coronavirus vaccine – weekly summary of Yellow Card reporting – Medicines and Healthcare products Regulatory Agency
Related opinion: Undermining the AstraZeneca jab is a dangerous act of political folly – The Guardian
“Based on current experience, the expected benefits of both COVID-19 vaccines in preventing COVID-19 and its serious complications far outweigh any known side effects”
Opinion | How to lose friends and alienate people? On the problems of vaccine passports
5 Apr, 2021 | 01:42h | UTCHow to lose friends and alienate people? On the problems of vaccine passports – The BMJ Opinion
Related: Resistance from health experts and business owners could doom ‘vaccine passports’ even before they launch – STAT AND How Vaccine Passports Will Worsen Inequities In Global Health – Microbiology AND Vaccine certificates: does the end justify the means? – The Lancet Microbe AND Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND “Vaccine Passport” Certification — Policy and Ethical Considerations – New England Journal of Medicine AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization
Commentary on Twitter
"All in all, there are reasons to conclude that vaccine passports for basic activities may actually undermine vaccine rollout by disincentivising the very populations who most need incentivising" @ReicherStephen @ProfJohnDrury https://t.co/UL9qfFiOcA
— The BMJ (@bmj_latest) April 2, 2021
Many hospitalized Covid-19 patients are given antibiotics. That’s a problem
5 Apr, 2021 | 01:33h | UTCMany hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT
Video: Why you can’t compare Covid-19 vaccines
2 Apr, 2021 | 09:33h | UTCWhy you can’t compare Covid-19 vaccines – Vox
Long Covid in the UK – More than a million affected in February, survey suggests
2 Apr, 2021 | 09:31h | UTCLong Covid: More than a million affected in February, survey suggests – BBC
Commentary on Twitter
YOUNG ADULTS MOST AFFECTED—Long-Covid symptoms are affecting about 1.1 million people in the U.K., with about half that number saying the disease is harming their day-to-day lives, government statistics show. Top #LongCovid age group? 25-34! Thread 🧵 https://t.co/Fwo8Opeqr6
— Eric Feigl-Ding (@DrEricDing) April 1, 2021
Why is it so hard to investigate the rare side effects of COVID vaccines?
2 Apr, 2021 | 09:28h | UTCWhy is it so hard to investigate the rare side effects of COVID vaccines? – Nature
[Press release – not published yet] Pfizer/BioNTech vaccine is 91% effective for at least 6 months
2 Apr, 2021 | 09:29h | UTCCommentaries: Ongoing trial shows Pfizer Covid-19 vaccine remains highly effective after six months – CNN AND Coronavirus: Pfizer jab ‘stopping 91% of cases in first six months’ – BBC AND Expert reaction to press release from Pfizer and BioNTech on efficacy and safety up to six months after second vaccine dose, including data from South Africa – Science Media Centre AND Pfizer’s COVID-19 vaccine effective after 6 months and works against problem variant – LiveScience
Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis
2 Apr, 2021 | 09:23h | UTCCommentaries: Covid-19 led to a global increase in stillbirths, maternal mortality, and depression, review finds – CNN AND COVID-19 pandemic and health-care disruptions: count the most vulnerable – The Lancet Global Health
Commentary on Twitter
NEW—Pregnancy outcomes worsened during the #COVID19 pandemic worldwide, with an increase in maternal deaths, stillbirth, ruptured ectopic pregnancies, and maternal depression.
New review of 40 studies from 17 countries in @LancetGH: https://t.co/GWBohu6b6k pic.twitter.com/4RzgtShYeH
— The Lancet (@TheLancet) April 1, 2021
Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
2 Apr, 2021 | 09:36h | UTCCommentary: If I’ve Had COVID-19, Do I Still Need Two Doses of Vaccine? – TIME AND The research is in: People who’ve already had COVID-19 need just one shot – Insider
Related: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary) AND Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2 – JAMA AND Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine – New England Journal of Medicine
Rapid point-of-care tests for diagnosing COVID-19 infection: the latest Cochrane evidence
2 Apr, 2021 | 09:21h | UTCOriginal review and commentaries: Systematic review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
Therapeutics and COVID-19 | WHO guideline update advises Ivermectin should only be used to treat COVID-19 within clinical trials
1 Apr, 2021 | 04:02h | UTCSummary and Infographic: Drug treatments for covid-19: living systematic review and network meta-analysis – The BMJ
Original guideline: Therapeutics and COVID-19: living guideline – World Health Organization
News release: WHO advises that ivermectin only be used to treat COVID-19 within clinical trials – World Health Organization
Commentary: WHO joins Europe, Merck in recommending against ivermectin for COVID-19 – Reuters
Commentary on Twitter
https://twitter.com/ThomasAgoritsas/status/1377372928451301384
M-A: Vitamin D supplementation to prevent acute respiratory infections
1 Apr, 2021 | 03:30h | UTCCommentaries: Vitamin D to prevent acute respiratory infections – The Lancet Diabetes & Endocrinology AND
Editorial | Vaccine certificates: does the end justify the means?
1 Apr, 2021 | 03:41h | UTCVaccine certificates: does the end justify the means? – The Lancet Microbe
Related: Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND “Vaccine Passport” Certification — Policy and Ethical Considerations – New England Journal of Medicine AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization
WHO: Sinopharm, Sinovac COVID-19 vaccine data show efficacy
1 Apr, 2021 | 03:58h | UTCSinopharm, Sinovac COVID-19 vaccine data show efficacy: WHO – Reuters
Commentary on Twitter
https://twitter.com/hildabast/status/1377377034180038659