Chest Medicine (all articles)
Long Covid in the UK – More than a million affected in February, survey suggests
2 Apr, 2021 | 09:31h | UTCLong Covid: More than a million affected in February, survey suggests – BBC
Commentary on Twitter
YOUNG ADULTS MOST AFFECTED—Long-Covid symptoms are affecting about 1.1 million people in the U.K., with about half that number saying the disease is harming their day-to-day lives, government statistics show. Top #LongCovid age group? 25-34! Thread ? https://t.co/Fwo8Opeqr6
— Eric Feigl-Ding (@DrEricDing) April 1, 2021
Why is it so hard to investigate the rare side effects of COVID vaccines?
2 Apr, 2021 | 09:28h | UTCWhy is it so hard to investigate the rare side effects of COVID vaccines? – Nature
[Press release – not published yet] Pfizer/BioNTech vaccine is 91% effective for at least 6 months
2 Apr, 2021 | 09:29h | UTCCommentaries: Ongoing trial shows Pfizer Covid-19 vaccine remains highly effective after six months – CNN AND Coronavirus: Pfizer jab ‘stopping 91% of cases in first six months’ – BBC AND Expert reaction to press release from Pfizer and BioNTech on efficacy and safety up to six months after second vaccine dose, including data from South Africa – Science Media Centre AND Pfizer’s COVID-19 vaccine effective after 6 months and works against problem variant – LiveScience
Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis
2 Apr, 2021 | 09:23h | UTCCommentaries: Covid-19 led to a global increase in stillbirths, maternal mortality, and depression, review finds – CNN AND COVID-19 pandemic and health-care disruptions: count the most vulnerable – The Lancet Global Health
Commentary on Twitter
NEW—Pregnancy outcomes worsened during the #COVID19 pandemic worldwide, with an increase in maternal deaths, stillbirth, ruptured ectopic pregnancies, and maternal depression.
New review of 40 studies from 17 countries in @LancetGH: https://t.co/GWBohu6b6k pic.twitter.com/4RzgtShYeH
— The Lancet (@TheLancet) April 1, 2021
Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19
2 Apr, 2021 | 09:36h | UTCCommentary: If I’ve Had COVID-19, Do I Still Need Two Doses of Vaccine? – TIME AND The research is in: People who’ve already had COVID-19 need just one shot – Insider
Related: Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection (studies and commentary) AND Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2 – JAMA AND Antibody Responses in Seropositive Persons after a Single Dose of SARS-CoV-2 mRNA Vaccine – New England Journal of Medicine
Rapid point-of-care tests for diagnosing COVID-19 infection: the latest Cochrane evidence
2 Apr, 2021 | 09:21h | UTCOriginal review and commentaries: Systematic review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
Therapeutics and COVID-19 | WHO guideline update advises Ivermectin should only be used to treat COVID-19 within clinical trials
1 Apr, 2021 | 04:02h | UTCSummary and Infographic: Drug treatments for covid-19: living systematic review and network meta-analysis – The BMJ
Original guideline: Therapeutics and COVID-19: living guideline – World Health Organization
News release: WHO advises that ivermectin only be used to treat COVID-19 within clinical trials – World Health Organization
Commentary: WHO joins Europe, Merck in recommending against ivermectin for COVID-19 – Reuters
Commentary on Twitter
?Our updated @WHO #LivingGuidance on #COVID19 now adding recommandation on #ivermectin to previous recs on #steroids #remdesivir #lopinavir #Hydroxychloroquine
?https://t.co/eV7BtVrvAf
?https://t.co/G3Eu18Vg0s#MichaelJacobs @Bram_Rochwerg @PerVandvik @diazjv @bmj_latest https://t.co/qdrBQIZK8e pic.twitter.com/s9TkO1afYs— Thomas Agoritsas, MD PhD (@ThomasAgoritsas) March 31, 2021
M-A: Vitamin D supplementation to prevent acute respiratory infections
1 Apr, 2021 | 03:30h | UTCCommentaries: Vitamin D to prevent acute respiratory infections – The Lancet Diabetes & Endocrinology AND
Editorial | Vaccine certificates: does the end justify the means?
1 Apr, 2021 | 03:41h | UTCVaccine certificates: does the end justify the means? – The Lancet Microbe
Related: Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND “Vaccine Passport” Certification — Policy and Ethical Considerations – New England Journal of Medicine AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization
WHO: Sinopharm, Sinovac COVID-19 vaccine data show efficacy
1 Apr, 2021 | 03:58h | UTCSinopharm, Sinovac COVID-19 vaccine data show efficacy: WHO – Reuters
Commentary on Twitter
WHO decision on Sinopharm & Sinovac vaccines coming in the next few weeks: signal from WHO at a press briefing that the decision may be positive https://t.co/HcbZnJ7WDE
— Hilda Bastian, PhD (@hildabast) March 31, 2021
AstraZeneca COVID vaccine 70% effective vs. B117 variant
1 Apr, 2021 | 03:55h | UTCAstraZeneca COVID vaccine 70% effective vs B117 variant – CIDRAP
Commentary on Twitter (thread – Click for more)
ASYMPTOMATIC & SYMPTOMATIC Efficacy of Oxford-AstraZeneca #COVID19 vaccine versus #B117 & non-B117 variants via 200k swabs in ~8500:?
Symptomatic #B117➡️ 70%
Asymptomatic #B117➡️ 29%
Other variants symptomatic➡️ 81.5%
Other variants asymptomatic➡️ 70%https://t.co/qSWYlHKP0g pic.twitter.com/gS7P9MCpyz
— Eric Feigl-Ding (@DrEricDing) March 31, 2021
[Press release – not published yet] Pfizer-BioNTech vaccine 100% effective against Covid-19 in adolescents
1 Apr, 2021 | 03:52h | UTCPress release: Pfizer-BioNTech Announce Positive Topline Results Of Pivotal Covid-19 Vaccine Study In Adolescents
Commentaries: The Pfizer-BioNTech Vaccine Is Said to Be Powerfully Protective in Adolescents – The New York Times AND Covid: Children ‘well protected by Pfizer vaccine’ – BBC AND Pfizer Says COVID-19 Vaccine Shows ‘100% Efficacy’ In Adolescents – NPR AND Pfizer says its COVID-19 vaccine protects younger teens – Associated Press AND Pfizer and BioNTech say vaccine prevents Covid-19 in adolescents – STAT
Commentaries on Twitter
Press release for BNT-Pfizer vaccine efficacy in 2,260 adolescents aged 12 to 15: 0 Covid-19 among vaccinated, 18 in placebo group. Adverse reactions similar to those in 16 to 25 year-olds (no extra data: could be quite high, so eyes on that) https://t.co/mCoLmCtpgv
— Hilda Bastian, PhD (@hildabast) March 31, 2021
This is really terrific
In trial of 2260 adolescents 12-15 year of age, Pfizer vaccine highly effective at preventing infections
18 infections in placebo group
0 infections in vaccine group
Robust antibody response
No serious side-effects
Looking forward to @US_FDA review https://t.co/VymGXOVb5E
— Ashish K. Jha, MD, MPH (@ashishkjha) March 31, 2021
Post-covid syndrome in individuals admitted to hospital with covid-19: retrospective cohort study
1 Apr, 2021 | 03:43h | UTC
Commentary on Twitter
Follow-up of nearly 48,000 hospitalized patients with covid-19 shows a high rate of readmission, death, and multi-organ disease (heart, diabetes, kidney, lung) compared with matched controls https://t.co/dzxVYdugz2 @bmj_latest pic.twitter.com/hWBn5w2XQf
— Eric Topol (@EricTopol) April 1, 2021
Bill Gates: 5 things you should know about variants
1 Apr, 2021 | 03:49h | UTC5 things you should know about variants – GatesNotes
Commentary on Twitter
Here are five things you should know if you want to understand how variants are (and aren’t) complicating the pandemic. https://t.co/rANiDcZynJ
— Bill Gates (@BillGates) March 31, 2021
Opinion | “Vaccine Passport” Certification — Policy and Ethical Considerations
1 Apr, 2021 | 03:40h | UTCRelated: Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND Vaccine certificates: does the end justify the means? – The Lancet Microbe AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization
Antibody evasion by the P.1 strain of SARS-CoV-2
31 Mar, 2021 | 03:36h | UTCAntibody evasion by the P.1 strain of SARS-CoV-2 – Cell
Commentary on Twitter (thread – Click for more)
An in-depth assessment of the P.1 (Brazil) variant
—less immune evasion than B.1.351 (South Africa) variant despite similar receptor binding domain mutations
—very good neutralization by mRNA vaccine via sera from vaccineshttps://t.co/2m0A1Pjs9O @CellCellPress today pic.twitter.com/uyV2eZdLQ9— Eric Topol (@EricTopol) March 30, 2021
Why indoor spaces are still prime COVID hotspots
31 Mar, 2021 | 03:35h | UTCWhy indoor spaces are still prime COVID hotspots – Nature
[Preprint] Single dose of AstraZeneca and Pfizer vaccines shows 62% efficacy for preventing disease and reduces viral load/transmissibility of SARS-CoV-2 in residents of Long-Term Care Facilities
31 Mar, 2021 | 03:38h | UTCCommentaries: Single dose of Pfizer and Oxford vaccines shows 60% efficacy in elderly care home residents – NewsMedical AND Care home residents gain 62% protection from single dose of COVID-19 vaccine – University College London
Commentary on Twitter (thread – click for more)
Good news! An updated study has found that ONE dose of either Pfizer’s OR AstraZeneca’s vaccine led to a 62% reduction in the risk of ANY infection and lower viral loads in those that were infected after 28 days. Long-Term Care Facility/High-Risk Setting.https://t.co/ajgoSOA4fj
— Mac n’ Chise ??? (@sailorrooscout) March 29, 2021
Transmissibility and transmission of respiratory viruses
31 Mar, 2021 | 03:33h | UTCTransmissibility and transmission of respiratory viruses – Nature Reviews Microbiology
Opinion | Covid-19 vaccine passports will harm sustainable development
31 Mar, 2021 | 03:31h | UTCCovid-19 vaccine passports will harm sustainable development – The BMJ Opinion
“Where you are born can predict how freely you will be able to travel for opportunity, education, and leisure. Being a citizen of certain countries grants people access to nearly the entire globe, whereas others face challenges just to legally leave the borders of the country they live in”
Opinion | Covid-19 vaccine passports and vaccine hesitancy: freedom or control?
31 Mar, 2021 | 03:29h | UTCCovid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion
“Recent debates around “vaccine passports,” or formal/mandatory certification of vaccination, point towards a potential widening societal divide between those who are vaccinated and those who are not.”
The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis
31 Mar, 2021 | 03:27h | UTC
M-A: Decreased mortality in acute respiratory distress syndrome patients treated with corticosteroids
30 Mar, 2021 | 03:01h | UTC
‘Real world’ study by CDC shows Pfizer and Moderna vaccines were 90% effective
30 Mar, 2021 | 03:27h | UTC‘Real world’ study by CDC shows Pfizer and Moderna vaccines were 90% effective – STAT
Commentary on Twitter (thread – Click for more)
Prospective study in the US finds mRNA vaccine efficacy against SARS-CoV-2 infection (symptomatic or not) of 90% (CI: 68–97) after 2 doses, & 80% (CI: 59–90) after 1 dose. (Wide CI because few people got infected)…1/2 https://t.co/RSf3xFtL29 HT @HelenBranswell
— Hilda Bastian, PhD (@hildabast) March 29, 2021
COVID-19, Personal Protective Equipment, and Human Performance
30 Mar, 2021 | 03:14h | UTCCOVID-19, Personal Protective Equipment, and Human Performance – Anesthesiology