Chest Medicine | Page 77 of 170 | Links Medicus Content Curation & Alerts in Medicine

Just out in @TheLancet what experts have said for a year

SARS-CoV2 spreads PRIMARILY via airborne route

Failure to act on this has hampered efforts to prevent spread of COVID

Thank you @trishgreenhalgh @linseymarr @kprather88 @j_g_allen, others who stuck to the evidence https://t.co/uuJcUIKWHE

— Ashish K. Jha, MD, MPH (@ashishkjha) April 16, 2021

China’s Sinovac COVID-19 vaccine 67% effective in preventing symptomatic infection, 85% effective in preventing hospitalizations and 80% effective in preventing deaths – Chile govt report

18 Apr, 2021 | 21:45h | UTC

China’s Sinovac COVID-19 vaccine 67% effective in preventing symptomatic infection – Chile govt report – Reuters

Commentary on Twitter (thread – click for more)

https://twitter.com/hildabast/status/1383183542495039490

A guideline to limit indoor airborne transmission of COVID-19

18 Apr, 2021 | 21:47h | UTC

A guideline to limit indoor airborne transmission of COVID-19 – Proceedings of the National Academy of Sciences

Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission

18 Apr, 2021 | 21:49h | UTC

Indoor Air Changes and Potential Implications for SARS-CoV-2 Transmission – JAMA

Commentary on Twitter (thread – click for more)

https://twitter.com/j_g_allen/status/1383073549380882438

Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination

18 Apr, 2021 | 21:43h | UTC

Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination – New England Journal of Medicine

Commentaries: Researchers Offer Algorithm for Managing Thrombosis and Thrombocytopenia After COVID-19 Vaccination – NEJM Journal Watch AND Blood Clots After COVID-19 Vaccination Linked to Immune Response: UK Report – TCTMD AND People with rare blood clots after a COVID-19 jab share an uncommon immune response – ScienceNews

Editorial: SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – “The very low prevalence of this complication of vaccination, however severe, relative to the benefits of preventing Covid-19 must be emphasized”

18 Apr, 2021 | 21:42h | UTC

SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia – New England Journal of Medicine

COVID vaccines and blood clots: five key questions

18 Apr, 2021 | 21:40h | UTC

COVID vaccines and blood clots: five key questions – Nature

Study shows past COVID-19 infection doesn’t fully protect young people against reinfection

18 Apr, 2021 | 21:35h | UTC

Study shows past COVID-19 infection doesn’t fully protect young people against reinfection – Mount Sinai School of Medicine

Original study: SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study – The Lancet Respiratory Medicine

Commentary on Twitter

Risk of covid reinfection in a prospective study of >3,000 Marine recruits
Prior covid: 82% reduced compared w/ no prior covid (+ when reinfections occurred, much less viral loads)
Protection correlated w/ higher spike IgG antibody levels https://t.co/7Jl154lwDX @LancetRespirMed pic.twitter.com/xKVLKm8AA6

— Eric Topol (@EricTopol) April 15, 2021

Study: Double masking improves protection from Covid-19 mostly by eliminating any gaps or poor-fitting areas of a mask

18 Apr, 2021 | 21:37h | UTC

Fitted Filtration Efficiency of Double Masking During the COVID-19 Pandemic – JAMA Internal Medicine

Commentaries: Fit matters most when double masking to protect yourself from COVID-19 – University of North Carolina Health Care AND Check your fit on that double mask if you want it to work against Covid, study says – CNN

Study Commentary | What if the EHR Age-Adjusts D-dimer for You?

18 Apr, 2021 | 21:04h | UTC

What if the EHR Age-Adjusts D-dimer for You? – Journal Feed

Original study: Multi-center implementation of automated age-adjusted D-dimer results reduces unnecessary PE imaging – The American Journal of Emergency Medicine (link to abstract – $ for full-text)

Study shows antihistamines may impair response to exercise training

16 Apr, 2021 | 06:06h | UTC

Histamine H₁ and H₂ receptors are essential transducers of the integrative exercise training response in humans – Science Advances

Commentary: Histamine-suppressing drugs found to reduce benefits of exercise – MedicalXpress

Commentary on Twitter (thread – click for more)

Extremely excited to finally share our newest paper: Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans. Published today in @ScienceAdvances. A thread: (1/12)https://t.co/R4FNiKWyG9 pic.twitter.com/U2HFHOY9eA

— Thibaux Van der Stede (@ThibauxV) April 14, 2021

[Preprint] Risk of rare blood clotting much higher for COVID-19 than for vaccines

16 Apr, 2021 | 06:37h | UTC

News release: Risk of rare blood clotting higher for COVID-19 than for vaccines – University of Oxford

Original study (preprint): Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine

Commentaries: Brain clots ‘more likely’ with Covid infection than vaccine – BBC AND Risk for Cerebral Venous Thrombosis Elevated After COVID-19 Diagnosis – NEJM Journal Watch AND Study: COVID much more likely than vaccines to cause blood clots – CIDRAP

Commentary on Twitter

There is an interesting new preprint out that will probably generate a lot of coverage at least in the UK. Essentially it argues that the risk of CVST is much higher from #covid19 than from vaccines.
Quick thread on this:https://t.co/0MdDU2z9bp

— Kai Kupferschmidt (@kakape) April 15, 2021

Evolving changes in mortality of 13,301 critically ill adult patients with COVID-19 over 8 months

16 Apr, 2021 | 06:35h | UTC

Evolving changes in mortality of 13,301 critically ill adult patients with COVID-19 over 8 months – Intensive Care Medicine

Commentary on Twitter

Our paper on covid-19 pandemic trends in the first 8 months in the pandemic at @yourICM. Patients are getting younger, less frail, and mortality decreased over time. Very poor outcomes for elder frail patients. https://t.co/DHJvr22zFl

— Fernando Zampieri (@f_g_zampieri) April 14, 2021

M-A: Treatment with hydroxychloroquine is associated with increased mortality in COVID-19 patients

16 Apr, 2021 | 06:30h | UTC

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials – Nature Communications

Commentaries on Twitter

The use of hydroxychloroquine in COVID19 will be remembered as one of the worst examples of medicine going against its core principle:
First Do No Harm. https://t.co/PGq4D5pJ1H

— Maurizio Cecconi (@DrMCecconi) April 15, 2021

What collaboration can achieve

Just out in @NatureComms our meta-analysis of 14 unpublished & 14 published RCTs on Hydroxychloroquine/ Choloroquine

Thanks so much to the great team – and special thanks for rapidly sharing the data of unpublished trials!https://t.co/Dg1DmAx1Kq

— Lars G. Hemkens (@LGHemkens) April 15, 2021