Chest Medicine (all articles)
Study shows past COVID-19 infection doesn’t fully protect young people against reinfection
18 Apr, 2021 | 21:35h | UTCOriginal study: SARS-CoV-2 seropositivity and subsequent infection risk in healthy young adults: a prospective cohort study – The Lancet Respiratory Medicine
Commentary on Twitter
Risk of covid reinfection in a prospective study of >3,000 Marine recruits
Prior covid: 82% reduced compared w/ no prior covid (+ when reinfections occurred, much less viral loads)
Protection correlated w/ higher spike IgG antibody levels https://t.co/7Jl154lwDX @LancetRespirMed pic.twitter.com/xKVLKm8AA6— Eric Topol (@EricTopol) April 15, 2021
Study: Double masking improves protection from Covid-19 mostly by eliminating any gaps or poor-fitting areas of a mask
18 Apr, 2021 | 21:37h | UTCFitted Filtration Efficiency of Double Masking During the COVID-19 Pandemic – JAMA Internal Medicine
Commentaries: Fit matters most when double masking to protect yourself from COVID-19 – University of North Carolina Health Care AND Check your fit on that double mask if you want it to work against Covid, study says – CNN
Study Commentary | What if the EHR Age-Adjusts D-dimer for You?
18 Apr, 2021 | 21:04h | UTCWhat if the EHR Age-Adjusts D-dimer for You? – Journal Feed
Original study: Multi-center implementation of automated age-adjusted D-dimer results reduces unnecessary PE imaging – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Study shows antihistamines may impair response to exercise training
16 Apr, 2021 | 06:06h | UTCCommentary: Histamine-suppressing drugs found to reduce benefits of exercise – MedicalXpress
Commentary on Twitter (thread – click for more)
Extremely excited to finally share our newest paper: Histamine H1 and H2 receptors are essential transducers of the integrative exercise training response in humans. Published today in @ScienceAdvances. A thread: (1/12)https://t.co/R4FNiKWyG9 pic.twitter.com/U2HFHOY9eA
— Thibaux Van der Stede (@ThibauxV) April 14, 2021
[Preprint] Risk of rare blood clotting much higher for COVID-19 than for vaccines
16 Apr, 2021 | 06:37h | UTCNews release: Risk of rare blood clotting higher for COVID-19 than for vaccines – University of Oxford
Original study (preprint): Cerebral venous thrombosis: a retrospective cohort study of 513,284 confirmed COVID-19 cases and a comparison with 489,871 people receiving a COVID-19 mRNA vaccine
Commentaries: Brain clots ‘more likely’ with Covid infection than vaccine – BBC AND Risk for Cerebral Venous Thrombosis Elevated After COVID-19 Diagnosis – NEJM Journal Watch AND Study: COVID much more likely than vaccines to cause blood clots – CIDRAP
Commentary on Twitter
There is an interesting new preprint out that will probably generate a lot of coverage at least in the UK. Essentially it argues that the risk of CVST is much higher from #covid19 than from vaccines.
Quick thread on this:https://t.co/0MdDU2z9bp— Kai Kupferschmidt (@kakape) April 15, 2021
Evolving changes in mortality of 13,301 critically ill adult patients with COVID-19 over 8 months
16 Apr, 2021 | 06:35h | UTC
Commentary on Twitter
Our paper on covid-19 pandemic trends in the first 8 months in the pandemic at @yourICM. Patients are getting younger, less frail, and mortality decreased over time. Very poor outcomes for elder frail patients. https://t.co/DHJvr22zFl
— Fernando Zampieri (@f_g_zampieri) April 14, 2021
M-A: Treatment with hydroxychloroquine is associated with increased mortality in COVID-19 patients
16 Apr, 2021 | 06:30h | UTC
Commentaries on Twitter
The use of hydroxychloroquine in COVID19 will be remembered as one of the worst examples of medicine going against its core principle:
First Do No Harm. https://t.co/PGq4D5pJ1H— Maurizio Cecconi (@DrMCecconi) April 15, 2021
What collaboration can achieve
Just out in @NatureComms our meta-analysis of 14 unpublished & 14 published RCTs on Hydroxychloroquine/ Choloroquine
Thanks so much to the great team – and special thanks for rapidly sharing the data of unpublished trials!https://t.co/Dg1DmAx1Kq
— Lars G. Hemkens (@LGHemkens) April 15, 2021
Perspective | Ivermectin is the new Hydroxychorloquine
16 Apr, 2021 | 06:28h | UTCIvermectin is the new Hydroxychorloquine – Science-Based Medicine
Video | Coronavirus variants: What you need to know
16 Apr, 2021 | 06:32h | UTCCoronavirus variants: What you need to know – Nature Video
Editorial: Covid-19 has redefined airborne transmission
16 Apr, 2021 | 06:26h | UTCCovid-19 has redefined airborne transmission – The BMJ
Commentaries: Future attempts to reduce Covid-19 spread should focus on tackling airborne transmission – News Medical AND Open the windows to curb COVID spread: experts – MedicalXpress
Related: CDC Updated Guidance: “It is possible for people to be infected through contact with contaminated surfaces or objects, but the risk is generally considered to be low” (CDC Guidance and more) AND Deep Cleaning Isn’t a Victimless Crime – The Atlantic
Were pregnant women more affected by COVID-19 in the second wave of the pandemic?
16 Apr, 2021 | 06:24h | UTCWere pregnant women more affected by COVID-19 in the second wave of the pandemic? – The Lancet
Vaccines alone will not stop Covid spreading – here’s why (visual guide to the “Swiss cheese model”)
15 Apr, 2021 | 06:53h | UTCVaccines alone will not stop Covid spreading – here’s why – BBC
Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – “we estimate that P.1 may be 1.7–2.4-fold more transmissible”
15 Apr, 2021 | 07:09h | UTCGenomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science
Commentary: The P.1 coronavirus variant is twice as transmissible as earlier strains – ScienceNews
Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient
15 Apr, 2021 | 06:51h | UTCPandemic Boosts an Old Idea—Bringing Acute Care to the Patient – JAMA
Related studies: Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates AND Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences – JAMA Internal Medicine
Case Report: Thrombotic Thrombocytopenia after Johnson & Johnson Vaccine
15 Apr, 2021 | 07:02h | UTCThrombotic Thrombocytopenia after Ad26.COV2.S Vaccination – New England Journal of Medicine
Related: U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots AND 4 Things to Know About the J&J Covid Vaccine Pause – Kaiser Health News AND Why Johnson & Johnson shots were paused — and why that’s so confusing – Vox AND Is it the adenovirus vaccine technology, used by AstraZeneca and Johnson & Johnson, causing blood clots? There’s no evidence yet – The Conversation
Opinion | Deep Cleaning Isn’t a Victimless Crime
15 Apr, 2021 | 06:56h | UTCDeep Cleaning Isn’t a Victimless Crime – The Atlantic
Related: CDC Updated Guidance: “It is possible for people to be infected through contact with contaminated surfaces or objects, but the risk is generally considered to be low” (CDC Guidance and more)
Observational study: Impact of the influenza vaccine on COVID-19 infection rates and severity
15 Apr, 2021 | 06:47h | UTCCommentary: Flu shot associated with fewer, less severe COVID cases – University of Michigan
Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients
15 Apr, 2021 | 06:49h | UTCCommentaries: Exercise may strongly protect against poor COVID-19 outcomes – CIDRAP AND One Good Way to Help Beat COVID: Exercise – HealthDay
New studies suggest SARS-CoV-2 variant B.1.1.7 is not more deadly, just more transmissible
14 Apr, 2021 | 02:12h | UTCCommentaries: Expert reaction to two papers looking at the transmissibility and severity of the B.1.1.7 variant – Science Media Centre AND UK coronavirus variant not more deadly, just spreads more easily, studies find – LiveScience
Why would a Covid vaccine cause rare blood clots? Researchers have found clues
14 Apr, 2021 | 02:14h | UTCWhy would a Covid vaccine cause rare blood clots? Researchers have found clues – STAT
Related: How could a COVID vaccine cause blood clots? Scientists race to investigate – Nature
U.S. regulators pause Johnson & Johnson vaccine rollout over rare (1 in a million) cases of blood clots
14 Apr, 2021 | 02:16h | UTCJoint CDC and FDA Statement on Johnson & Johnson COVID-19 Vaccine – U.S. Food & Drug Administration
Commentaries: Covid-19: US suspends Johnson and Johnson vaccine rollout over blood clots – BMJ AND CDC and FDA recommend US pause use of Johnson & Johnson’s Covid-19 vaccine over blood clot concerns – CNN AND US halts J&J COVID vaccine after reports of blood clots – CIDRAP AND U.S. urges pause on use of Johnson & Johnson Covid-19 vaccine after rare blood clotting cases – CIDRAP
RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19
13 Apr, 2021 | 05:30h | UTCOriginal study (preprint): Inhaled budesonide for COVID-19 in people at higher risk of adverse outcomes in the community: interim analyses from the PRINCIPLE trial – medRxiv
Commentary: Covid: Asthma drug ‘speeds up recovery at home’ – BBC
Related study: Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19 (study and commentaries)
Tobacco Taxes Are Most Effective Yet Least Implemented Tactics, Says WHO
13 Apr, 2021 | 05:06h | UTCTobacco Taxes Are Most Effective Yet Least Implemented Tactics, Says WHO – Health Policy Watch
Guidance: WHO technical manual on tobacco tax administration – World Health Organization
Infectivity of severe acute respiratory syndrome coronavirus 2 in children compared with adults
13 Apr, 2021 | 05:27h | UTCCommentary: Children may be less infectious in spreading SARS-CoV-2 to others – News Medical
M-A: Post-extubation oxygenation strategies in acute respiratory failure – NPPV or HFNC may reduce the risk of endotracheal reintubation but not mortality
12 Apr, 2021 | 00:42h | UTC