Chest Medicine (all articles)
Ten simple steps to improve ventilation in healthcare facilities
11 May, 2021 | 09:27h | UTCTen simple steps to improve ventilation in healthcare facilities – Essential Critical Care
Commentary on Twitter
I've written ten simple steps to improve ventilation in healthcare facilities… with no jargon and loads of photos.
With expert input from @akm5376 @vfmcneill & @kartc from @IndiaCOVIDSOS.
Download here: https://t.co/OzsDXfPavm#COVIDisAirborne pic.twitter.com/UtsRO0IgWr
— Bex Sierra (@Global_ICU) May 5, 2021
Just 2% of SARS-CoV-2−positive individuals carry 90% of the virus circulating in communities
11 May, 2021 | 09:31h | UTC
Commentary on Twitter
Covid-19 is a supercarrier story. (!)
90% of the virus load (circulating virions) is harbored by only 2% of individuals
[So much for the 80/20 Pareto principle]https://t.co/zidXh7DBjt@PNASNews by @Sara_Sawyer_ @CUBoulder @BioFrontiers and colleagues pic.twitter.com/xIPpgaGLTE— Eric Topol (@EricTopol) May 10, 2021
A global database of COVID-19 vaccinations
11 May, 2021 | 09:28h | UTCA global database of COVID-19 vaccinations – Nature Human Behaviour
See website: Statistics and Research: Coronavirus (COVID-19) Vaccinations – Our World in Data
Commentaries on Twitter
Since the beginning of the COVID vaccinations we brought together the global data.
It's the most cited resource that @OurWorldInData has ever produced. Thousands of citations every week.
Just now our vaccination dataset has been published in Nature!https://t.co/COmCMNSbw2
— Max Roser (@MaxCRoser) May 10, 2021
A stunner.
One of my favorite graphics from the pandemic: the story of the unprecedented #SARSCoV2 vaccines
Published today @NatureHumBehav @OurWorldInData https://t.co/raPq8H3DSq@redouad @MaxCRoser @_HannahRitchie @EOrtizOspina @lucasrodesg @lucasrodesg @JoeHasell @appel_cam pic.twitter.com/x1LYobAOkM— Eric Topol (@EricTopol) May 10, 2021
Mild COVID-19 infection is very unlikely to cause lasting heart damage
11 May, 2021 | 09:23h | UTCMild COVID-19 infection is very unlikely to cause lasting heart damage – Imperial College London
Commentary on Twitter
Mild Covid infection is unlikely to cause lasting heart damage, according to a study led by University College London. It's the largest & most detailed study to date into mild Covid infection and its longer-term impact on the heart https://t.co/pZ0Wgnf9zp pic.twitter.com/b1T9AClQeX
— delthia ricks ? (@DelthiaRicks) May 9, 2021
Cohort study: Non-steroidal anti-inflammatory drug use is not associated with higher mortality or increased severity of COVID-19
11 May, 2021 | 09:25h | UTCCommentaries: Largest study to date confirms non-steroidal anti-inflammatory medications do not result in worse COVID-19 outcomes – The Lancet AND Non-steroidal anti-inflammatory drug use in COVID-19 – The Lancet Rheumatology AND Ibuprofen, other NSAIDs not tied to worse COVID illness, death – CIDRAP
Related study with similar findings: Nonsteroidal Antiinflammatory Drugs and Susceptibility to COVID‐19 – Arthritis & Rheumatism
Commentary on Twitter
NEW Research—Non-steroidal anti-inflammatory drugs (NSAIDs) do not increase the mortality or severity of #COVID19: findings from more than 72,000 people in the ISARIC @CCPUKstudy https://t.co/NPJzuS1wAx #LancetRheumatology #OpenAccess pic.twitter.com/LjG6O7e3F8
— The Lancet Rheumatology (@TheLancetRheum) May 7, 2021
Researchers tie severe immunosuppression to chronic COVID-19 and virus variants
11 May, 2021 | 09:21h | UTCResearchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants – JAMA
A ‘more rapidly spreading virus’ (B.1.617 variant) is fueling India’s mega COVID-19 surge, WHO chief scientist says
11 May, 2021 | 09:16h | UTCSee also: WHO Upgrades Virus Mutation Driving India’s COVID Surge To ‘Variant of Concern’ – Global Cases Start To ‘Plateau’ – Health Policy Watch AND Why India needs oxygen more urgently than vaccines – Vox AND WHO names B1617 fourth COVID-19 variant of concern – CIDRAP
Mucormycosis: The ‘black fungus’ maiming Covid patients in India
11 May, 2021 | 09:14h | UTCMucormycosis: The ‘black fungus’ maiming Covid patients in India – BBC
See also: Potentially fatal ‘black fungus’ infections on the rise in India’s COVID-19 patients – LiveScience AND A potentially fatal fungal infection is cropping up among India’s Covid patients. – The New York Times AND WHO says virus strain in India a ‘variant of concern’ as Europe eases curbs – MedicalXpress
Commentary on Twitter (thread – click for more)
Doctors in India are concerned about an increase in a highly fatal fungal infection affecting cases & recently recovered from #COVID19. Mucormycosis, is a mold that attacks the respiratory tract, potentially eroding facial structures & harming the brain.?https://t.co/1rHU2nM346
— Eric Feigl-Ding (@DrEricDing) May 10, 2021
New WHO Online Course: Initial approach to the acutely ill patient with COVID-19.
10 May, 2021 | 01:21h | UTC
WHO Infographic | How to care COVID-19 patients with mild symptoms at home: information for health care workers.
10 May, 2021 | 01:17h | UTCCOVID-19 home care bundle for health care workers – World Health Organization
Commentary on Twitter
How to care #COVID19 patients with mild symptoms at home: information for health care workershttps://t.co/r09i9k0zGl pic.twitter.com/i5ihXQrhzg
— World Health Organization (WHO) (@WHO) May 8, 2021
Covid-19: Most people admitted to hospital after vaccination were infected before immunity could develop, research shows.
10 May, 2021 | 01:14h | UTC
Commentary on Twitter
"#Covid19: Most people admitted to hospital after vaccination were infected before immunity could develop, research" https://t.co/wi30LkafC7
"…highlighting the importance of maintaining social distancing & understanding that immunity develops over time…"#ScienceUpFirst!
— Timothy Caulfield (@CaulfieldTim) May 7, 2021
Opinion | Aerosol generating procedures: are they of relevance for transmission of SARS-CoV-2?
10 May, 2021 | 01:16h | UTC
Commentary on Twitter
"The term AGP has neither face validity nor construct validity. We should focus on the risk in plain sight: caring for patients with COVID-19 who are coughing."
New paper arguing to bury the term 'aerosol generating procedure'.
Great work from Bristol team. pic.twitter.com/fKTFRKcmy1
— Trisha Greenhalgh ? #CovidIsAirborne (@trishgreenhalgh) May 7, 2021
CDC website now emphasizes coronavirus spreads in the air.
10 May, 2021 | 01:11h | UTCCDC website now emphasizes coronavirus spreads in the air – CNN
Commentary on Twitter
1/ A radical shift today by @CDCgov, finally aligning itself with science on the modes of transmission, and throwing away the 1910 error of considering "close contact" a mode of transmission!https://t.co/5pP25OTY5d
— Jose-Luis Jimenez (@jljcolorado) May 8, 2021
Here’s what’s known about the coronavirus variants.
10 May, 2021 | 01:12h | UTCHere’s what’s known about the coronavirus variants – CNN
Viewpoint | Precision Medicine for COVID-19: Phenotype Anarchy or Promise Realized?
10 May, 2021 | 01:09h | UTCPrecision Medicine for COVID-19: Phenotype Anarchy or Promise Realized? – JAMA
Perspective | Flu Has Disappeared Worldwide during the COVID Pandemic: “The public health measures that slow the spread of the novel coronavirus work really well on influenza”.
10 May, 2021 | 01:08h | UTCFlu Has Disappeared Worldwide during the COVID Pandemic – Scientific American
One third of patients hospitalized with COVID-19 have lung changes after a year
7 May, 2021 | 08:37h | UTCCommentaries: One third of patients hospitalized with COVID-19 have lung changes after a year – University of Southampton AND An integrated understanding of long-term sequelae after acute COVID-19 – The Lancet Respiratory Medicine
Cohort study: Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S. 11 excess venous thromboembolic events per 100 000 vaccinations; 2.5 excess cerebral venous thrombosis per 100 000 vaccinations.
7 May, 2021 | 08:33h | UTCEditorial: Thromboembolism and the Oxford-AstraZeneca vaccine – The BMJ
Commentaries: Thrombosis and bleeding after the Oxford-AstraZeneca covid-19 vaccination – The BMJ Opinion AND Putting risks into context: covid-19 vaccines and blood clots – The BMJ Opinion AND Expert reaction to study from Denmark and Norway looking at rare blood clots after the Oxford-AstraZeneca vaccine – Science Media Centre
Commentary on Twitter
NEW research sheds more light on rate of rare blood clots after Oxford-AstraZeneca vaccine
Rate of adverse events low; benefits of the vaccine still outweigh risks in most situations, say researchershttps://t.co/LslgvzWlWi @Pottegard
— The BMJ (@bmj_latest) May 6, 2021
Opinion | Covid-19: Sputnik vaccine rockets, thanks to Lancet boost
7 May, 2021 | 08:31h | UTCCovid-19: Sputnik vaccine rockets, thanks to Lancet boost – The BMJ
Commentary on Twitter
Journals risk being used in place of regulators when they publish studies of novel vaccines that have not yet been authorised by a major regulator @DoctorChrisVT unpicks the story of the Sputnik V vaccine https://t.co/lYf7l0lXcy
— The BMJ (@bmj_latest) May 6, 2021
COVID-19 has caused 6.9 million deaths globally, more than double what official reports show
7 May, 2021 | 08:35h | UTCReport: Estimation of total mortality due to COVID-19 – Institute for Health Metrics and Evaluation
Commentaries: New analysis finds global Covid death toll is double official estimates – STAT AND Global COVID-19 death toll more than double official estimates – IHME – Reuters
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
7 May, 2021 | 08:30h | UTC
Commentary on Twitter
We forget that covid-19 is a new disease, never having been seen until late 2019, w/ different features than any prior illness. A truly outstanding review today on its pathophysiology https://t.co/8gx2w8r1xf @LancetRespirMed @osuchm and colleagues pic.twitter.com/WGIfI2nb9B
— Eric Topol (@EricTopol) May 6, 2021
In shock move, US backs waiving patents on COVID vaccines. “The development from the Biden administration draws cheers from public health researchers and ire from drugmakers.”
6 May, 2021 | 09:10h | UTCIn shock move, US backs waiving patents on COVID vaccines – Nature
See also: U.S. will back proposal to waive intellectual property rights and boost Covid-19 vaccine production – STAT AND Statement from the Executive Director of UNAIDS, Winnie Byanyima on the decision by the United States of America to support the TRIPS waiver for COVID-19 vaccines – UNAIDS AND WHO Director-General commends United States decision to support temporary waiver on intellectual property rights for COVID-19 vaccines – World Health Organization
Commentary on Twitter
These extraordinary times and circumstances of call for extraordinary measures.
The US supports the waiver of IP protections on COVID-19 vaccines to help end the pandemic and we’ll actively participate in @WTO negotiations to make that happen. pic.twitter.com/96ERlboZS8
— Ambassador Katherine Tai (@AmbassadorTai) May 5, 2021
Cohort study shows inadequate antibody response to mRNA SARS-CoV-2 vaccine among kidney transplant recipients.
6 May, 2021 | 09:01h | UTC
Commentary on Twitter
The studies of mRNA vax in people with transplants are getting bigger: still the same message. Some protection, but not enough. This time, 308 people with kidney transplants in Israel, BNT-Pfizer vaccine https://t.co/Otvt8F11my
— Hilda Bastian, PhD (@hildabast) May 6, 2021
Observational study in Israel: Pfizer-BioNTech is 95.3% effective against SARS-CoV-2 infection.
6 May, 2021 | 09:04h | UTCCommentaries: Expert reaction to Israel nation-wide study looking at Pfizer vaccine effectiveness – Science Media Centre AND Covid-19: Two doses of Pfizer vaccine are “highly effective” against infection, hospital admission, and death, study finds – The BMJ
Observational study in Qatar: Pfizer–BioNTech Covid vaccine is 89.5% effective against B.1.1.7 variant and 75.0% effective against B.1.351 variant. Vaccine effectiveness against severe, critical, or fatal disease with any SARS-CoV-2 variant was very high, at 97.4%.
6 May, 2021 | 09:06h | UTC
Commentary on Twitter
?GET BOTH DOSES! Great variants & #COVID19 vaccine news—Pfizer/BioNTech vaccine had great efficacy of 89.5% vs #B117 ?? variant & 75% vs #B1351 ?? variant for infection—but only with 2 doses. The 1 dose efficacy was just ~29% vs #B117 & ~17% vs #B1351. ?https://t.co/SprUfggnmh pic.twitter.com/VDWHiLsQLL
— Eric Feigl-Ding (@DrEricDing) May 6, 2021